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| | PRIM1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (418 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa) |
| | PSMD12 | Proteasome 26S subunit, non-ATPase 12. (456 aa) |
| | A0A4W2HXK5 | Uncharacterized protein. (129 aa) |
| | RCBTB1 | RCC1 and BTB domain containing protein 1. (531 aa) |
| | UBE2S | Ubiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (223 aa) |
| | A0A4W2I5C3 | Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (70 aa) |
| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | A0A4W2I9K4 | Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (58 aa) |
| | PSME1 | Proteasome activator subunit 1. (249 aa) |
| | RBX1 | RING-type domain-containing protein. (128 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (607 aa) |
| | PSMC1 | Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (462 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | A0A4W2ESI7 | Proteasome endopeptidase complex. (157 aa) |
| | PSMA3 | Proteasome subunit alpha type. (266 aa) |
| | RPA3 | Replication protein A3. (121 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (320 aa) |
| | RFC1 | Replication factor C subunit 1. (1146 aa) |
| | KXD1 | KxDL domain-containing protein. (212 aa) |
| | TM7SF3 | Transmembrane 7 superfamily member 3. (570 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | CDC27 | Cell division cycle 27. (831 aa) |
| | PSMA6 | Proteasome subunit alpha type. (246 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (194 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2289 aa) |
| | LIG1 | DNA ligase. (1303 aa) |
| | PSME4 | Proteasome activator subunit 4. (1843 aa) |
| | ANAPC15 | Uncharacterized protein. (121 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (836 aa) |
| | POLD1 | DNA polymerase. (1106 aa) |
| | A0A4W2CNN4 | Uncharacterized protein. (207 aa) |
| | PSMA1 | Proteasome subunit alpha type. (269 aa) |
| | A0A4W2CQU3 | Proteasome endopeptidase complex. (239 aa) |
| | ORC6 | Origin recognition complex subunit 6. (203 aa) |
| | PSMB6 | Proteasome subunit beta. (239 aa) |
| | A0A4W2CR66 | PROTEASOME_ALPHA_1 domain-containing protein. (200 aa) |
| | A0A4W2F2V9 | Uncharacterized protein. (63 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa) |
| | PSMB3 | Proteasome subunit beta. (236 aa) |
| | SKP2 | F-box domain-containing protein. (436 aa) |
| | SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa) |
| | A0A4W2DY12 | RPA_C domain-containing protein. (270 aa) |
| | GMNN | Geminin DNA replication inhibitor. (186 aa) |
| | CDC23 | Cell division cycle 23. (607 aa) |
| | PRIM2 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (510 aa) |
| | RFC2 | Replication factor C subunit 2. (352 aa) |
| | ANAPC2 | Anaphase promoting complex subunit 2; Belongs to the cullin family. (888 aa) |
| | POLE3 | DNA polymerase epsilon 3, accessory subunit. (147 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | A0A4W2FLF9 | RING-type domain-containing protein. (108 aa) |
| | PSMA4 | Proteasome subunit alpha type. (261 aa) |
| | ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (809 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | PSMA8 | Proteasome subunit alpha type. (250 aa) |
| | POLD2 | DNA polymerase delta 2, accessory subunit. (580 aa) |
| | PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1061 aa) |
| | PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (440 aa) |
| | A0A4W2DPH7 | Ubiquitin-like domain-containing protein. (120 aa) |
| | A0A4W2DNY5 | Uncharacterized protein. (286 aa) |
| | ATAD5 | ATPase family AAA domain containing 5. (1893 aa) |
| | MEIOB | Meiosis specific with OB-fold. (472 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | PSMD5 | Proteasome 26S subunit, non-ATPase 5. (554 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (859 aa) |
| | POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa) |
| | PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (326 aa) |
| | A0A4W2D801 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (274 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (385 aa) |
| | RFC4 | Replication factor C subunit 4. (364 aa) |
| | UBE2C | Ubiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa) |
| | PSMB11 | Proteasome subunit beta. (289 aa) |
| | CDC26 | Cell division cycle 26. (85 aa) |
| | A0A4W2D3W4 | Ubiquitin-like domain-containing protein. (160 aa) |
| | ANAPC1 | Anaphase promoting complex subunit 1. (1958 aa) |
| | PSME2 | Proteasome activator subunit 2. (239 aa) |
| | FZR1 | Fizzy and cell division cycle 20 related 1. (523 aa) |
| | ORC3 | Origin recognition complex subunit 3. (713 aa) |
| | ORC2 | Origin recognition complex subunit 2. (577 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | A0A4W2CWK4 | Skp1_POZ domain-containing protein. (65 aa) |
| | UBC | Ubiquitin C. (1146 aa) |
| | RPA2 | RPA_C domain-containing protein. (270 aa) |
| | CDC16 | Cell division cycle 16. (620 aa) |
| | A0A4W2GF22 | DOC domain-containing protein. (83 aa) |
| | PSMD9 | PDZ domain-containing protein. (221 aa) |
| | PSMD2 | Proteasome 26S subunit, non-ATPase 2. (1688 aa) |
| | PSMA7 | Proteasome subunit alpha type. (248 aa) |
| | A0A4W2GSS9 | Uncharacterized protein. (47 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (892 aa) |
| | FAM89A | Family with sequence similarity 89 member A. (178 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (322 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) |
| | ANAPC7 | Anaphase promoting complex subunit 7. (598 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (270 aa) |
| | PSME3 | Proteasome activator subunit 3. (231 aa) |
| | RFC5 | Replication factor C subunit 5. (527 aa) |
| | RFC3 | Replication factor C subunit 3. (356 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (421 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (902 aa) |
| | A0A4W2BS58 | RING-type domain-containing protein. (81 aa) |
| | A0A4W2BX47 | Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (79 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (534 aa) |
| | POLD4 | Uncharacterized protein. (315 aa) |
| | GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (808 aa) |
| | PSMB8 | Proteasome subunit beta. (276 aa) |
| | UBE2E1 | Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa) |
| | ANAPC10 | DOC domain-containing protein. (327 aa) |
| | UBE2D1 | Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (437 aa) |
| | A0A4W2C7C3 | KxDL domain-containing protein. (179 aa) |
| | ANAPC5 | Anaphase promoting complex subunit 5. (755 aa) |
| | POLA2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (600 aa) |
| | ANAPC11 | RING-type domain-containing protein. (84 aa) |
| | ANAPC16 | Anaphase promoting complex subunit 16. (110 aa) |
| | A0A4W2E0Q1 | Ubiquitin-like domain-containing protein. (77 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (350 aa) |
| | GINS3 | GINS complex subunit 3. (216 aa) |
| | RCBTB2 | RCC1 and BTB domain containing protein 2. (554 aa) |
| | MCM9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1139 aa) |
| | POLD3 | Uncharacterized protein. (425 aa) |
| | GINS1 | GINS complex subunit 1. (196 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (411 aa) |
| | A0A4W2EBR9 | Uncharacterized protein. (221 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | POLE4 | DNA polymerase epsilon 4, accessory subunit. (120 aa) |
| | CDT1 | Chromatin licensing and DNA replication factor 1. (600 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) |
| | A0A4W2EMD5 | Proteasome endopeptidase complex. (296 aa) |
| | ORC5 | Origin recognition complex subunit 5. (446 aa) |
| | TM4SF19 | Uncharacterized protein. (209 aa) |
| | CCNA2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (430 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (376 aa) |
| | GINS2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (214 aa) |
| | FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | MCM8 | MCM domain-containing protein; Belongs to the MCM family. (832 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
