STRINGSTRING
PSMD1 PSMD1 PSMA4 PSMA4 CUL1 CUL1 SKP1 SKP1 MNAT1 MNAT1 SKP2 SKP2 PSMB6 PSMB6 A0A4W2CQU3 A0A4W2CQU3 PSMA1 PSMA1 A0A4W2CNN4 A0A4W2CNN4 A0A4W2CFU1 A0A4W2CFU1 RPS27A RPS27A PSMC4 PSMC4 PSMA6 PSMA6 CDC25A CDC25A A0A4W2C7C3 A0A4W2C7C3 PSMD11 PSMD11 CDK3 CDK3 PSMB8 PSMB8 PSMD3 PSMD3 A0A4W2BX47 A0A4W2BX47 CCNA1 CCNA1 PSMB3 PSMB3 PSMC2 PSMC2 A0A4W2F2V9 A0A4W2F2V9 KXD1 KXD1 PSMD14 PSMD14 PSMA3 PSMA3 A0A4W2ESI7 A0A4W2ESI7 PSMB5 PSMB5 PSMC1 PSMC1 A0A4W2EMD5 A0A4W2EMD5 PTK6 PTK6 CDK4 CDK4 CCNE2 CCNE2 CDKN1A CDKN1A A0A4W2ED36 A0A4W2ED36 PSMB9 PSMB9 A0A4W2EBR9 A0A4W2EBR9 CCNE1 CCNE1 CCND1 CCND1 CDC25B CDC25B KIAA2012 KIAA2012 PSMD8 PSMD8 A0A4W2E0Q1 A0A4W2E0Q1 CABLES1 CABLES1 A0A4W2DPH7 A0A4W2DPH7 WEE2 WEE2 PSMB2 PSMB2 PSMC6 PSMC6 A0A4W2CR66 A0A4W2CR66 CKS1B CKS1B CCNH CCNH PSMD5 PSMD5 A0A4W2DNY5 A0A4W2DNY5 FZR1 FZR1 PSME2 PSME2 CKS2 CKS2 A0A4W2D3W4 A0A4W2D3W4 A0A4W2D7W0 A0A4W2D7W0 PSMD4 PSMD4 A0A4W2D801 A0A4W2D801 PSMF1 PSMF1 UBC UBC A0A4W2CWK4 A0A4W2CWK4 PSMB7 PSMB7 PSMB1 PSMB1 PSME1 PSME1 A0A4W2I9K4 A0A4W2I9K4 PSMB10 PSMB10 A0A4W2I5C3 A0A4W2I5C3 RB1 RB1 WEE1 WEE1 CDK7 CDK7 PSMD12 PSMD12 CDK2 CDK2 PSMA5 PSMA5 CDKN1B CDKN1B PSMD13 PSMD13 CCNA2 CCNA2 PSME3 PSME3 PSMB4 PSMB4 PSMD7 PSMD7 CDKN1C CDKN1C A0A4W2GSS9 A0A4W2GSS9 PSMA7 PSMA7 PSMD2 PSMD2 PSMD9 PSMD9 PSMC3 PSMC3 PSMC5 PSMC5 A0A4W2G5Q0 A0A4W2G5Q0
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
SKP2F-box domain-containing protein. (436 aa)
PSMB6Proteasome subunit beta. (239 aa)
A0A4W2CQU3Proteasome endopeptidase complex. (239 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
A0A4W2CNN4Uncharacterized protein. (207 aa)
A0A4W2CFU1Protein kinase domain-containing protein. (79 aa)
RPS27AUbiquitin-like domain-containing protein. (194 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
CDC25ACell division cycle 25A. (525 aa)
A0A4W2C7C3KxDL domain-containing protein. (179 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (437 aa)
CDK3Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa)
PSMB8Proteasome subunit beta. (276 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
A0A4W2BX47Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (79 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (421 aa)
PSMB3Proteasome subunit beta. (236 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
A0A4W2F2V9Uncharacterized protein. (63 aa)
KXD1KxDL domain-containing protein. (212 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (320 aa)
PSMA3Proteasome subunit alpha type. (266 aa)
A0A4W2ESI7Proteasome endopeptidase complex. (157 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (462 aa)
A0A4W2EMD5Proteasome endopeptidase complex. (296 aa)
PTK6Tyrosine-protein kinase. (450 aa)
CDK4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (303 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (404 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (161 aa)
A0A4W2ED36Uncharacterized protein. (295 aa)
PSMB9Proteasome subunit beta. (219 aa)
A0A4W2EBR9Uncharacterized protein. (221 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (411 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (428 aa)
CDC25BCell division cycle 25B. (574 aa)
KIAA2012KIAA2012. (1163 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
A0A4W2E0Q1Ubiquitin-like domain-containing protein. (77 aa)
CABLES1Cdk5 and Abl enzyme substrate 1. (678 aa)
A0A4W2DPH7Ubiquitin-like domain-containing protein. (120 aa)
WEE2Wee1-like protein kinase. (566 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
A0A4W2CR66PROTEASOME_ALPHA_1 domain-containing protein. (200 aa)
CKS1BCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
CCNHCyclin H; Belongs to the cyclin family. (329 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (554 aa)
A0A4W2DNY5Uncharacterized protein. (286 aa)
FZR1Fizzy and cell division cycle 20 related 1. (523 aa)
PSME2Proteasome activator subunit 2. (239 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
A0A4W2D3W4Ubiquitin-like domain-containing protein. (160 aa)
A0A4W2D7W0Uncharacterized protein. (96 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (385 aa)
A0A4W2D801Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (274 aa)
PSMF1Proteasome inhibitor subunit 1. (270 aa)
UBCUbiquitin C. (1146 aa)
A0A4W2CWK4Skp1_POZ domain-containing protein. (65 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSME1Proteasome activator subunit 1. (249 aa)
A0A4W2I9K4Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (58 aa)
PSMB10Proteasome subunit beta. (273 aa)
A0A4W2I5C3Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (70 aa)
RB1RB transcriptional corepressor 1. (928 aa)
WEE1Wee1-like protein kinase. (646 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
CCNA2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (430 aa)
PSME3Proteasome activator subunit 3. (231 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (322 aa)
CDKN1CUncharacterized protein. (438 aa)
A0A4W2GSS9Uncharacterized protein. (47 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
PSMD2Proteasome 26S subunit, non-ATPase 2. (1688 aa)
PSMD9PDZ domain-containing protein. (221 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (440 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
A0A4W2G5Q0Protein kinase domain-containing protein. (79 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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