STRINGSTRING
A0A4W2DPM7 A0A4W2DPM7 WASF3 WASF3 GIT1 GIT1 RAB7A RAB7A DIAPH3 DIAPH3 ARHGAP17 ARHGAP17 RNFT1 RNFT1 DLC1 DLC1 AMIGO3 AMIGO3 OPHN1 OPHN1 DEF6 DEF6 ARHGAP20 ARHGAP20 ARHGAP45 ARHGAP45 ARHGAP10 ARHGAP10 WIPF2 WIPF2 LRRC24 LRRC24 DOCK1 DOCK1 FAM13C FAM13C ARHGAP23 ARHGAP23 SPATA13 SPATA13 A0A4W2C3B4 A0A4W2C3B4 ARHGEF10 ARHGEF10 SGSM3 SGSM3 CDC42EP1 CDC42EP1 IQGAP1 IQGAP1 CYBA CYBA RAC3 RAC3 PIK3R1 PIK3R1 ERBIN ERBIN FGD5 FGD5 NCF2 NCF2 RAC1 RAC1 ABL2 ABL2 PARD6A PARD6A PLD2 PLD2 BAIAP2L1 BAIAP2L1 LRFN5 LRFN5 A0A4W2CE36 A0A4W2CE36 ANKRD33B ANKRD33B KIAA0355 KIAA0355 PLEKHG2 PLEKHG2 A0A4W2CHM1 A0A4W2CHM1 ARHGAP39 ARHGAP39 PREX2 PREX2 CAV1 CAV1 BCAM BCAM ALS2 ALS2 MPP7 MPP7 JPH1 JPH1 SWAP70 SWAP70 PLEKHG6 PLEKHG6 BCR BCR GIT2 GIT2 A0A4W2CR10 A0A4W2CR10 SRGAP1 SRGAP1 FERMT2 FERMT2 BHLHE23 BHLHE23 DOCK2 DOCK2 ARHGEF25 ARHGEF25 MCF2L MCF2L ARHGAP27 ARHGAP27 PAK5 PAK5 LBR LBR A0A4W2CXT7 A0A4W2CXT7 AMIGO2 AMIGO2 ARHGAP21 ARHGAP21 ARHGAP31 ARHGAP31 RACGAP1 RACGAP1 LOC113897870 LOC113897870 PLEKHG3 PLEKHG3 NCKAP1L NCKAP1L SESTD1 SESTD1 IQGAP2 IQGAP2 AMIGO1 AMIGO1 ARHGEF7 ARHGEF7 ECT2 ECT2 KTN1 KTN1 DOCK9 DOCK9 MYO9B MYO9B ARHGAP15 ARHGAP15 ARHGEF11 ARHGEF11 CDC42 CDC42 ARHGAP30 ARHGAP30 ARHGEF18 ARHGEF18 ARHGEF19 ARHGEF19 DOCK6 DOCK6 ARAP3 ARAP3 PAK2 PAK2 WAS WAS RASGRF2 RASGRF2 MCF2L2 MCF2L2 LOC113888476 LOC113888476 RALBP1 RALBP1 PIK3CA PIK3CA MCAM MCAM NCF1 NCF1 DOCK5 DOCK5 WIPF1 WIPF1 FMN2 FMN2 A0A4W2DUQ2 A0A4W2DUQ2 WASHC1 WASHC1 VAV2 VAV2 TIAM1 TIAM1 IQGAP3 IQGAP3 BAIAP2 BAIAP2 NCF4 NCF4 CLRN3 CLRN3 A0A4W2E385 A0A4W2E385 PAK4 PAK4 NISCH NISCH SH3BP1 SH3BP1 ABI2 ABI2 ABR ABR ARHGAP32 ARHGAP32 CDC42EP4 CDC42EP4 JPH3 JPH3 ARHGAP12 ARHGAP12 FMNL1 FMNL1 ARHGAP33 ARHGAP33 MPP3 MPP3 ARHGEF39 ARHGEF39 LEMD3 LEMD3 SOS2 SOS2 FARP1 FARP1 ABI1 ABI1 DOCK8 DOCK8 DOCK4 DOCK4 RBM39 RBM39 NOX3 NOX3 SLC1A5 SLC1A5 CHN2 CHN2 ARHGAP44 ARHGAP44 YKT6 YKT6 ARHGEF15 ARHGEF15 ECT2L ECT2L DOCK10 DOCK10 ARHGDIA ARHGDIA CIT CIT PLEKHG1 PLEKHG1 DEPDC1B DEPDC1B PAK6 PAK6 CDC42BPA CDC42BPA SNAP23 SNAP23 VRK2 VRK2 ARAP1 ARAP1 FERMT1 FERMT1 TIAM2 TIAM2 FMN1 FMN1 SYDE2 SYDE2 TAGAP TAGAP JPH2 JPH2 ARHGAP29 ARHGAP29 ARHGAP25 ARHGAP25 ARHGAP22 ARHGAP22 JPH4 JPH4 FGD6 FGD6 VAV3 VAV3 ARHGEF5 ARHGEF5 NCKAP1 NCKAP1 PLD1 PLD1 A0A4W2EU02 A0A4W2EU02 CHN1 CHN1 BNIPL BNIPL A0A4W2EUW4 A0A4W2EUW4 FARP2 FARP2 NGEF NGEF GMIP GMIP PIK3R3 PIK3R3 OLIG2 OLIG2 ARAP2 ARAP2 EPHA2 EPHA2 FAM13A FAM13A PKN1 PKN1 RSPH1 RSPH1 CYFIP2 CYFIP2 DOCK7 DOCK7 ARHGEF4 ARHGEF4 CYFIP1 CYFIP1 WASF1 WASF1 MORN4 MORN4 WASF2 WASF2 KALRN KALRN VAV1 VAV1 JAG1 JAG1 CLRN2 CLRN2 MAPK1IP1L MAPK1IP1L ARHGAP9 ARHGAP9 PIK3R2 PIK3R2 ESYT1 ESYT1 ARHGAP42 ARHGAP42 ANKRD33 ANKRD33 ARHGAP24 ARHGAP24 CYBB CYBB PREX1 PREX1 VANGL1 VANGL1 ITGB1 ITGB1 GNA13 GNA13 PLEKHG4 PLEKHG4 TAOK3 TAOK3 ARHGAP35 ARHGAP35 RNFT2 RNFT2 LAMTOR1 LAMTOR1 OLIG3 OLIG3 BRK1 BRK1 ARHGAP5 ARHGAP5 PKN2 PKN2 DOCK3 DOCK3 ABI3 ABI3 SRGAP2 SRGAP2 FAM13B FAM13B ARHGAP26 ARHGAP26 ARHGAP1 ARHGAP1 PAK1 PAK1 MORN3 MORN3 SOS1 SOS1 RBM23 RBM23 SRGAP3 SRGAP3 OLIG1 OLIG1 TFRC TFRC A0A4W2BME5 A0A4W2BME5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A4W2DPM7TPR_REGION domain-containing protein. (325 aa)
WASF3WASP family member 3. (501 aa)
GIT1GIT ArfGAP 1. (770 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
DIAPH3Diaphanous related formin 3. (1184 aa)
ARHGAP17Rho GTPase activating protein 17. (871 aa)
RNFT1Ring finger protein, transmembrane 1. (433 aa)
DLC1DLC1 Rho GTPase activating protein. (1169 aa)
AMIGO3Adhesion molecule with Ig like domain 3. (519 aa)
OPHN1Oligophrenin 1. (685 aa)
DEF6DEF6 guanine nucleotide exchange factor. (701 aa)
ARHGAP20Rho GTPase activating protein 20. (1185 aa)
ARHGAP45Rho GTPase activating protein 45. (1158 aa)
ARHGAP10Rho GTPase activating protein 10. (1037 aa)
WIPF2WAS/WASL interacting protein family member 2. (511 aa)
LRRC24Leucine rich repeat containing 24. (497 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1888 aa)
FAM13CFamily with sequence similarity 13 member C. (582 aa)
ARHGAP23Rho GTPase activating protein 23. (1728 aa)
SPATA13Uncharacterized protein. (1260 aa)
A0A4W2C3B4Uncharacterized protein. (423 aa)
ARHGEF10Rho guanine nucleotide exchange factor 10. (1366 aa)
SGSM3Small G protein signaling modulator 3. (763 aa)
CDC42EP1CDC42 effector protein 1. (361 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1710 aa)
CYBACytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (191 aa)
RAC3Rac family small GTPase 3. (258 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ERBINErbb2 interacting protein. (1460 aa)
FGD5FYVE, RhoGEF and PH domain containing 5. (1517 aa)
NCF2Neutrophil cytosolic factor 2. (575 aa)
RAC1Rac family small GTPase 1. (257 aa)
ABL2Tyrosine-protein kinase. (1182 aa)
PARD6APar-6 family cell polarity regulator alpha. (344 aa)
PLD2Phospholipase. (1088 aa)
BAIAP2L1BAI1 associated protein 2 like 1. (536 aa)
LRFN5Leucine rich repeat and fibronectin type III domain containing 5. (717 aa)
A0A4W2CE36Uncharacterized protein. (1403 aa)
ANKRD33BAnkyrin repeat domain 33B. (488 aa)
KIAA0355KIAA0355. (1071 aa)
PLEKHG2Pleckstrin homology and RhoGEF domain containing G2. (1394 aa)
A0A4W2CHM1Uncharacterized protein. (1509 aa)
ARHGAP39Rho GTPase activating protein 39. (1151 aa)
PREX2Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2. (1605 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (211 aa)
BCAMBasal cell adhesion molecule (Lutheran blood group). (628 aa)
ALS2Alsin Rho guanine nucleotide exchange factor ALS2. (1656 aa)
MPP7Membrane palmitoylated protein 7; Belongs to the MAGUK family. (576 aa)
JPH1Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (658 aa)
SWAP70Switching B cell complex subunit SWAP70. (585 aa)
PLEKHG6Pleckstrin homology and RhoGEF domain containing G6. (791 aa)
BCRBCR activator of RhoGEF and GTPase. (1283 aa)
GIT2GIT ArfGAP 2. (759 aa)
A0A4W2CR10Uncharacterized protein. (866 aa)
SRGAP1SLIT-ROBO Rho GTPase activating protein 1. (1085 aa)
FERMT2Fermitin family member 2. (706 aa)
BHLHE23Basic helix-loop-helix family member e23. (222 aa)
DOCK2Dedicator of cytokinesis 2; Belongs to the DOCK family. (1830 aa)
ARHGEF25Uncharacterized protein. (625 aa)
MCF2LMCF.2 cell line derived transforming sequence like. (982 aa)
ARHGAP27Rho GTPase activating protein 27. (871 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
LBRLamin B receptor. (621 aa)
A0A4W2CXT7Uncharacterized protein. (347 aa)
AMIGO2Adhesion molecule with Ig like domain 2. (591 aa)
ARHGAP21Rho GTPase activating protein 21. (1980 aa)
ARHGAP31Rho GTPase activating protein 31. (1451 aa)
RACGAP1Rac GTPase activating protein 1. (651 aa)
LOC113897870Phorbol-ester/DAG-type domain-containing protein. (360 aa)
PLEKHG3Pleckstrin homology and RhoGEF domain containing G3. (1208 aa)
NCKAP1LNCK associated protein 1 like. (1134 aa)
SESTD1SEC14 and spectrin domain containing 1. (696 aa)
IQGAP2IQ motif containing GTPase activating protein 2. (1575 aa)
AMIGO1Adhesion molecule with Ig like domain 1. (493 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (862 aa)
ECT2Epithelial cell transforming 2. (944 aa)
KTN1Kinectin 1. (1357 aa)
DOCK9Dedicator of cytokinesis 9; Belongs to the DOCK family. (2170 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2150 aa)
ARHGAP15Rho GTPase activating protein 15. (472 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1590 aa)
CDC42Cell division cycle 42. (191 aa)
ARHGAP30Rho GTPase activating protein 30. (1096 aa)
ARHGEF18Uncharacterized protein. (1345 aa)
ARHGEF19Rho guanine nucleotide exchange factor 19. (807 aa)
DOCK6Dedicator of cytokinesis 6; Belongs to the DOCK family. (2047 aa)
ARAP3ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3. (1548 aa)
PAK2Non-specific serine/threonine protein kinase. (600 aa)
WASWASP actin nucleation promoting factor. (559 aa)
RASGRF2Ras protein specific guanine nucleotide releasing factor 2. (1240 aa)
MCF2L2MCF.2 cell line derived transforming sequence-like 2. (1089 aa)
LOC113888476Rho-GAP domain-containing protein. (166 aa)
RALBP1RalA binding protein 1. (635 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
MCAMMelanoma cell adhesion molecule. (645 aa)
NCF1Neutrophil cytosolic factor 1. (392 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1864 aa)
WIPF1WH2 domain-containing protein. (509 aa)
FMN2Formin 2. (1611 aa)
A0A4W2DUQ2FH2 domain-containing protein. (248 aa)
WASHC1WASH complex subunit 1. (491 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1591 aa)
IQGAP3IQ motif containing GTPase activating protein 3. (1635 aa)
BAIAP2BAI1 associated protein 2. (568 aa)
NCF4Neutrophil cytosolic factor 4. (339 aa)
CLRN3Clarin 3. (227 aa)
A0A4W2E385Uncharacterized protein. (613 aa)
PAK4Non-specific serine/threonine protein kinase. (593 aa)
NISCHNischarin. (1508 aa)
SH3BP1Uncharacterized protein. (693 aa)
ABI2Abl interactor 2. (542 aa)
ABRABR activator of RhoGEF and GTPase. (1349 aa)
ARHGAP32Rho GTPase activating protein 32. (2137 aa)
CDC42EP4CDC42 effector protein 4. (351 aa)
JPH3Junctophilin 3. (793 aa)
ARHGAP12Rho GTPase activating protein 12. (868 aa)
FMNL1Formin like 1. (1169 aa)
ARHGAP33Rho GTPase activating protein 33. (1127 aa)
MPP3Membrane palmitoylated protein 3; Belongs to the MAGUK family. (585 aa)
ARHGEF39Rho guanine nucleotide exchange factor 39. (335 aa)
LEMD3LEM domain containing 3. (913 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
FARP1FERM, ARH/RhoGEF and pleckstrin domain protein 1. (1046 aa)
ABI1Abl interactor 1. (508 aa)
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2110 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (1973 aa)
RBM39RNA binding motif protein 39. (530 aa)
NOX3NADPH oxidase 3. (566 aa)
SLC1A5Amino acid transporter. (539 aa)
CHN2Chimaerin; GTPase-activating protein for p21-rac. (468 aa)
ARHGAP44Rho GTPase activating protein 44. (804 aa)
YKT6YKT6 v-SNARE homolog; Belongs to the synaptobrevin family. (198 aa)
ARHGEF15Rho guanine nucleotide exchange factor 15. (847 aa)
ECT2LEpithelial cell transforming 2 like. (959 aa)
DOCK10Dedicator of cytokinesis 10; Belongs to the DOCK family. (2199 aa)
ARHGDIARho GDP dissociation inhibitor alpha. (204 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2068 aa)
PLEKHG1Pleckstrin homology and RhoGEF domain containing G1. (1380 aa)
DEPDC1BDEP domain containing 1B. (529 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
CDC42BPANon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1810 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
VRK2VRK serine/threonine kinase 2. (509 aa)
ARAP1ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1. (1740 aa)
FERMT1Fermitin family member 1. (711 aa)
TIAM2T cell lymphoma invasion and metastasis 2. (1568 aa)
FMN1Formin 1. (1419 aa)
SYDE2Synapse defective Rho GTPase homolog 2. (1446 aa)
TAGAPT cell activation RhoGTPase activating protein. (911 aa)
JPH2Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (695 aa)
ARHGAP29Rho GTPase activating protein 29. (1269 aa)
ARHGAP25Rho GTPase activating protein 25. (644 aa)
ARHGAP22Rho GTPase activating protein 22. (722 aa)
JPH4Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (628 aa)
FGD6FYVE, RhoGEF and PH domain containing 6. (1432 aa)
VAV3Vav guanine nucleotide exchange factor 3. (977 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5. (1655 aa)
NCKAP1NCK associated protein 1. (1139 aa)
PLD1Phospholipase. (1126 aa)
A0A4W2EU02t-SNARE coiled-coil homology domain-containing protein. (161 aa)
CHN1Chimaerin; GTPase-activating protein for p21-rac. (459 aa)
BNIPLBCL2 interacting protein like. (356 aa)
A0A4W2EUW4Uncharacterized protein. (691 aa)
FARP2FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1039 aa)
NGEFNeuronal guanine nucleotide exchange factor. (667 aa)
GMIPGEM interacting protein. (1024 aa)
PIK3R3Uncharacterized protein. (461 aa)
OLIG2Oligodendrocyte transcription factor 2. (327 aa)
ARAP2ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2. (1726 aa)
EPHA2EPH receptor A2. (1007 aa)
FAM13AFamily with sequence similarity 13 member A. (1046 aa)
PKN1Protein kinase N1. (956 aa)
RSPH1Radial spoke head component 1. (308 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
DOCK7Dedicator of cytokinesis 7; Belongs to the DOCK family. (2147 aa)
ARHGEF4Rho guanine nucleotide exchange factor 4. (688 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
WASF1WASP family member 1. (570 aa)
MORN4MORN repeat containing 4. (146 aa)
WASF2WASP family member 2. (493 aa)
KALRNKalirin RhoGEF kinase. (2987 aa)
VAV1Vav guanine nucleotide exchange factor 1. (872 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
CLRN2Clarin 2. (232 aa)
MAPK1IP1LMitogen-activated protein kinase 1 interacting protein 1 like. (240 aa)
ARHGAP9Rho GTPase activating protein 9. (740 aa)
PIK3R2Uncharacterized protein. (724 aa)
ESYT1Extended synaptotagmin 1. (1116 aa)
ARHGAP42Rho GTPase activating protein 42. (874 aa)
ANKRD33ANK_REP_REGION domain-containing protein. (267 aa)
ARHGAP24Rho GTPase activating protein 24. (749 aa)
CYBBCytochrome b-245 beta chain. (570 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1653 aa)
VANGL1Vang-like protein. (537 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
GNA13G protein subunit alpha 13. (377 aa)
PLEKHG4Pleckstrin homology and RhoGEF domain containing G4. (1196 aa)
TAOK3TAO kinase 3. (898 aa)
ARHGAP35Rho GTPase activating protein 35. (1500 aa)
RNFT2Ring finger protein, transmembrane 2. (449 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa)
OLIG3Oligodendrocyte transcription factor 3. (272 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)
ARHGAP5Rho GTPase activating protein 5. (1503 aa)
PKN2Protein kinase N2. (981 aa)
DOCK3Dedicator of cytokinesis 3; Belongs to the DOCK family. (2025 aa)
ABI3ABI family member 3. (359 aa)
SRGAP2Uncharacterized protein. (1084 aa)
FAM13BFamily with sequence similarity 13 member B. (938 aa)
ARHGAP26Rho GTPase activating protein 26. (815 aa)
ARHGAP1Rho GTPase activating protein 1. (439 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
MORN3MORN repeat containing 3. (241 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1598 aa)
RBM23RNA binding motif protein 23. (463 aa)
SRGAP3SLIT-ROBO Rho GTPase activating protein 3. (1099 aa)
OLIG1Oligodendrocyte transcription factor 1. (266 aa)
TFRCTransferrin receptor. (842 aa)
A0A4W2BME5Rho-GAP domain-containing protein. (152 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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