(45 nodes) SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain network (Bos indicus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PRDM11	PR/SET domain 11. (1177 aa)
	SETD6	N-lysine methyltransferase SETD6; Protein-lysine N-methyltransferase. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily. (450 aa)
	PRDM6	PR/SET domain 6. (597 aa)
	EHMT1	Euchromatic histone lysine methyltransferase 1. (1293 aa)
	SUV39H2	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (430 aa)
	PRDM5	Zinc finger protein. (630 aa)
	PRDM1	PR/SET domain 1. (842 aa)
	NSD3	Nuclear receptor binding SET domain protein 3. (1439 aa)
	SETD7	Histone-lysine N-methyltransferase SETD7; Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes. (366 aa)
	SETD1A	SET domain containing 1A, histone lysine methyltransferase. (1708 aa)
	SETDB2	SET domain bifurcated histone lysine methyltransferase 2. (700 aa)
	SMYD4	SET and MYND domain containing 4. (802 aa)
	LOC113880535	Uncharacterized protein. (306 aa)
	SMYD3	SET and MYND domain containing 3. (428 aa)
	PRDM14	PR/SET domain 14. (571 aa)
	SMYD5	SMYD family member 5. (447 aa)
	SMYD1	SET and MYND domain containing 1. (490 aa)
	KMT2B	Lysine methyltransferase 2B. (2703 aa)
	KMT5A	Lysine methyltransferase 5A. (352 aa)
	SETD1B	SET domain containing 1B, histone lysine methyltransferase. (1966 aa)
	SMYD2	SET and MYND domain containing 2. (490 aa)
	EHMT2	Euchromatic histone lysine methyltransferase 2. (1389 aa)
	KMT5B	Lysine methyltransferase 5B. (911 aa)
	KMT2A	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3710 aa)
	SETD5	SET domain containing 5. (1478 aa)
	SUV39H1	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (411 aa)
	EZH1	Enhancer of zeste 1 polycomb repressive complex 2 subunit. (747 aa)
	NSD2	Nuclear receptor binding SET domain protein 2. (1365 aa)
	EZH2	Enhancer of zeste 2 polycomb repressive complex 2 subunit. (779 aa)
	A0A4W2D682	Uncharacterized protein. (639 aa)
	PRDM16	PR/SET domain 16. (1282 aa)
	KMT2C	Lysine methyltransferase 2C. (4969 aa)
	PRDM8	PR/SET domain 8. (685 aa)
	SETDB1	SET domain bifurcated histone lysine methyltransferase 1. (1290 aa)
	KMT2E	Lysine methyltransferase 2E. (1859 aa)
	SETD2	SET domain containing 2, histone lysine methyltransferase. (2563 aa)
	PRDM15	PR/SET domain 15. (1243 aa)
	KMT5C	Lysine methyltransferase 5C. (438 aa)
	PRDM2	PR/SET domain 2. (1705 aa)
	A0A4W2EEA8	Uncharacterized protein. (724 aa)
	KMT2D	Lysine methyltransferase 2D. (5579 aa)
	NSD1	Nuclear receptor binding SET domain protein 1. (2698 aa)
	MECOM	MDS1 and EVI1 complex locus. (1230 aa)
	ASH1L	ASH1 like histone lysine methyltransferase. (2905 aa)
	PRDM12	PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; Belongs to the class V-like SAM-binding methyltransferase superfamily. (361 aa)

Your Current Organism:

Bos indicus

NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A4W2D682	EHMT1	A0A4W2D682	A0A4W2GVS1	Uncharacterized protein.	Euchromatic histone lysine methyltransferase 1.	0.457
A0A4W2D682	EHMT2	A0A4W2D682	A0A4W2C3K6	Uncharacterized protein.	Euchromatic histone lysine methyltransferase 2.	0.449
A0A4W2D682	EZH1	A0A4W2D682	A0A4W2CXJ9	Uncharacterized protein.	Enhancer of zeste 1 polycomb repressive complex 2 subunit.	0.442
A0A4W2D682	EZH2	A0A4W2D682	A0A4W2D3W3	Uncharacterized protein.	Enhancer of zeste 2 polycomb repressive complex 2 subunit.	0.404
A0A4W2D682	KMT5A	A0A4W2D682	A0A4W2CD55	Uncharacterized protein.	Lysine methyltransferase 5A.	0.488
A0A4W2D682	KMT5B	A0A4W2D682	A0A4W2BXW0	Uncharacterized protein.	Lysine methyltransferase 5B.	0.460
A0A4W2D682	KMT5C	A0A4W2D682	A0A4W2ECD8	Uncharacterized protein.	Lysine methyltransferase 5C.	0.408
A0A4W2D682	LOC113880535	A0A4W2D682	A0A4W2BNB2	Uncharacterized protein.	Uncharacterized protein.	0.456
A0A4W2D682	NSD1	A0A4W2D682	A0A4W2ETM8	Uncharacterized protein.	Nuclear receptor binding SET domain protein 1.	0.460
A0A4W2D682	NSD2	A0A4W2D682	A0A4W2D164	Uncharacterized protein.	Nuclear receptor binding SET domain protein 2.	0.435
A0A4W2D682	NSD3	A0A4W2D682	A0A4W2HB52	Uncharacterized protein.	Nuclear receptor binding SET domain protein 3.	0.450
A0A4W2D682	SETD1A	A0A4W2D682	A0A4W2IIB7	Uncharacterized protein.	SET domain containing 1A, histone lysine methyltransferase.	0.434
A0A4W2D682	SETD1B	A0A4W2D682	A0A4W2CD22	Uncharacterized protein.	SET domain containing 1B, histone lysine methyltransferase.	0.431
A0A4W2D682	SETD2	A0A4W2D682	A0A4W2DQL4	Uncharacterized protein.	SET domain containing 2, histone lysine methyltransferase.	0.450
A0A4W2D682	SETD7	A0A4W2D682	A0A4W2HIQ9	Uncharacterized protein.	Histone-lysine N-methyltransferase SETD7; Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes.	0.471
A0A4W2D682	SETDB1	A0A4W2D682	A0A4W2DC75	Uncharacterized protein.	SET domain bifurcated histone lysine methyltransferase 1.	0.537
A0A4W2D682	SETDB2	A0A4W2D682	A0A4W2BP80	Uncharacterized protein.	SET domain bifurcated histone lysine methyltransferase 2.	0.465
A0A4W2D682	SMYD1	A0A4W2D682	A0A4W2CFJ2	Uncharacterized protein.	SET and MYND domain containing 1.	0.409
A0A4W2D682	SMYD3	A0A4W2D682	A0A4W2IKL4	Uncharacterized protein.	SET and MYND domain containing 3.	0.532
A0A4W2D682	SMYD4	A0A4W2D682	A0A4W2BP17	Uncharacterized protein.	SET and MYND domain containing 4.	0.436

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