STRINGSTRING
RUVBL1 RUVBL1 A0A4W2DWM1 A0A4W2DWM1 RAD51 RAD51 ABCA4 ABCA4 MDN1 MDN1 A0A4W2CZ23 A0A4W2CZ23 A0A4W2CYB4 A0A4W2CYB4 A0A4W2CXT3 A0A4W2CXT3 A0A4W2CXL9 A0A4W2CXL9 A0A4W2CXI7 A0A4W2CXI7 A0A4W2CXI3 A0A4W2CXI3 A0A4W2CX70 A0A4W2CX70 ATAD2B ATAD2B DNAH6 DNAH6 A0A4W2CUZ4 A0A4W2CUZ4 A0A4W2CTZ2 A0A4W2CTZ2 NVL NVL SPAST SPAST A0A4W2CPH3 A0A4W2CPH3 A0A4W2CP07 A0A4W2CP07 SPATA5L1 SPATA5L1 NLRP5 NLRP5 ABCG5 ABCG5 LOC113876112 LOC113876112 DNAH9 DNAH9 ABCF1 ABCF1 DHX37 DHX37 DNAH10 DNAH10 PEX6 PEX6 ABCC2 ABCC2 A0A4W2E0D4 A0A4W2E0D4 LOC113896243 LOC113896243 SPATA5 SPATA5 ABCA12 ABCA12 ABCC10 ABCC10 MCM4 MCM4 CFTR CFTR ABCB10 ABCB10 TRIP13 TRIP13 ABCA5 ABCA5 DNAH5 DNAH5 ABCA6 ABCA6 ABCA9 ABCA9 PSMC4 PSMC4 YME1L1 YME1L1 IGHMBP2 IGHMBP2 ABCC6 ABCC6 NAIP NAIP LONP2 LONP2 LOC113875392 LOC113875392 CLPB CLPB VPS4A VPS4A A0A4W2DDA1 A0A4W2DDA1 A0A4W2DDE7 A0A4W2DDE7 A0A4W2DDV8 A0A4W2DDV8 LOC113902481 LOC113902481 A0A4W2DG11 A0A4W2DG11 ABCB4 ABCB4 DHX15 DHX15 ORC1 ORC1 KATNAL1 KATNAL1 MCM7 MCM7 ABCA3 ABCA3 ATAD5 ATAD5 A0A4W2DPR4 A0A4W2DPR4 RFC2 RFC2 ABCC1 ABCC1 VPS4B VPS4B RAD51D RAD51D MMAA MMAA DNAH8 DNAH8 CDC6 CDC6 DMC1 DMC1 RUVBL2 RUVBL2 ABCD4 ABCD4 BCS1L BCS1L MCM8 MCM8 AFG3L2 AFG3L2 RAD51B RAD51B ABCG4 ABCG4 FIGN FIGN ATG9A ATG9A KATNA1 KATNA1 ABCC5 ABCC5 PSMC3 PSMC3 PSMC5 PSMC5 ABCB9 ABCB9 FIGNL2 FIGNL2 ABCC3 ABCC3 ABCE1 ABCE1 DNAH7 DNAH7 PSMC2 PSMC2 A0A4W2EJE7 A0A4W2EJE7 A0A4W2EJI6 A0A4W2EJI6 ABCC8 ABCC8 NLRC5 NLRC5 TOR3A TOR3A ABCC11 ABCC11 SPG7 SPG7 DNAH2 DNAH2 TAP1 TAP1 MCM3 MCM3 LOC113881324 LOC113881324 A0A4W2BUQ1 A0A4W2BUQ1 KATNAL2 KATNAL2 DNAH3 DNAH3 VWA8 VWA8 A0A4W2EZ96 A0A4W2EZ96 ABCC9 ABCC9 ABCG2 ABCG2 LOC113902483 LOC113902483 ATAD2 ATAD2 ABCA10 ABCA10 NLRP2 NLRP2 ATP5F1B ATP5F1B TOR2A TOR2A GPN1 GPN1 SNRNP200 SNRNP200 PSMC1 PSMC1 ABCA1 ABCA1 ABCB8 ABCB8 A0A4W2ETK4 A0A4W2ETK4 FIGNL1 FIGNL1 ABCB11 ABCB11 RFC1 RFC1 ABCG1 ABCG1 ABCB5 ABCB5 ABCA7 ABCA7 DYNC1H1 DYNC1H1 RFC5 RFC5 MCM9 MCM9 NSF NSF VCP VCP A0A4W2EC47 A0A4W2EC47 AK9 AK9 ASCC3 ASCC3 A0A4W2EDB4 A0A4W2EDB4 DYNC2H1 DYNC2H1 LOC113888438 LOC113888438 NAV1 NAV1 ATAD1 ATAD1 ABCC12 ABCC12 RAD17 RAD17 ABCD2 ABCD2 NUBP1 NUBP1 A0A4W2BKC3 A0A4W2BKC3 RFC3 RFC3 DNAH1 DNAH1 A0A4W2BPB6 A0A4W2BPB6 CHTF18 CHTF18 NAV2 NAV2 WRNIP1 WRNIP1 A0A4W2DCI8 A0A4W2DCI8 ABCA13 ABCA13 DNAH11 DNAH11 PSMC6 PSMC6 ABCF3 ABCF3 PEX1 PEX1 RFC4 RFC4 NAV3 NAV3 ATAD3A ATAD3A LONP1 LONP1 ABCD3 ABCD3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
A0A4W2DWM1Uncharacterized protein. (1655 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
ABCA4ATP binding cassette subfamily A member 4. (2281 aa)
MDN1Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5577 aa)
A0A4W2CZ23Uncharacterized protein. (934 aa)
A0A4W2CYB4Uncharacterized protein. (1285 aa)
A0A4W2CXT3Uncharacterized protein. (882 aa)
A0A4W2CXL9Uncharacterized protein. (895 aa)
A0A4W2CXI7Uncharacterized protein. (1289 aa)
A0A4W2CXI3Uncharacterized protein. (873 aa)
A0A4W2CX70Uncharacterized protein. (1279 aa)
ATAD2BATPase family AAA domain containing 2B. (1472 aa)
DNAH6Dynein axonemal heavy chain 6. (4154 aa)
A0A4W2CUZ4Uncharacterized protein. (1230 aa)
A0A4W2CTZ2Uncharacterized protein. (1104 aa)
NVLNuclear VCP like. (855 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (613 aa)
A0A4W2CPH3RING-type domain-containing protein. (5204 aa)
A0A4W2CP07RING-type domain-containing protein. (5131 aa)
SPATA5L1Spermatogenesis associated 5 like 1. (767 aa)
NLRP5NLR family pyrin domain containing 5. (1098 aa)
ABCG5ABC transporter domain-containing protein. (648 aa)
LOC113876112NACHT domain-containing protein. (937 aa)
DNAH9Dynein axonemal heavy chain 9. (4486 aa)
ABCF1ATP binding cassette subfamily F member 1. (845 aa)
DHX37DEAH-box helicase 37. (1155 aa)
DNAH10Dynein axonemal heavy chain 10. (4532 aa)
PEX6Peroxisomal biogenesis factor 6. (980 aa)
ABCC2ATP binding cassette subfamily C member 2. (1543 aa)
A0A4W2E0D4ABC transporter domain-containing protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (488 aa)
LOC113896243Uncharacterized protein. (1293 aa)
SPATA5Spermatogenesis associated 5. (868 aa)
ABCA12ATP binding cassette subfamily A member 12. (2596 aa)
ABCC10ATP binding cassette subfamily C member 10. (1492 aa)
MCM4DNA helicase; Belongs to the MCM family. (836 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1481 aa)
ABCB10ATP binding cassette subfamily B member 10. (727 aa)
TRIP13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (436 aa)
ABCA5ATP binding cassette subfamily A member 5. (1642 aa)
DNAH5Dynein axonemal heavy chain 5. (4622 aa)
ABCA6ATP binding cassette subfamily A member 6. (1598 aa)
ABCA9ATP binding cassette subfamily A member 9. (1585 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
YME1L1YME1 like 1 ATPase. (715 aa)
IGHMBP2Immunoglobulin mu DNA binding protein 2. (981 aa)
ABCC6ATP binding cassette subfamily C member 6. (1504 aa)
NAIPNLR family apoptosis inhibitory protein. (1406 aa)
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (852 aa)
LOC113875392AAA domain-containing protein. (775 aa)
CLPBClpB homolog, mitochondrial AAA ATPase chaperonin. (707 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
A0A4W2DDA1Uncharacterized protein. (998 aa)
A0A4W2DDE7Uncharacterized protein. (1243 aa)
A0A4W2DDV8Uncharacterized protein. (781 aa)
LOC113902481Uncharacterized protein. (1250 aa)
A0A4W2DG11Uncharacterized protein. (1289 aa)
ABCB4Uncharacterized protein. (1275 aa)
DHX15DEAH-box helicase 15. (795 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (859 aa)
KATNAL1Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...] (489 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
ABCA3ATP binding cassette subfamily A member 3. (1704 aa)
ATAD5ATPase family AAA domain containing 5. (1893 aa)
A0A4W2DPR4Uncharacterized protein. (1641 aa)
RFC2Replication factor C subunit 2. (352 aa)
ABCC1ATP binding cassette subfamily C member 1. (1544 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (530 aa)
RAD51DRAD51 paralog D. (418 aa)
MMAAMetabolism of cobalamin associated A. (421 aa)
DNAH8Dynein axonemal heavy chain 8. (4492 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (607 aa)
DMC1DNA meiotic recombinase 1; Belongs to the RecA family. (340 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
ABCD4ATP binding cassette subfamily D member 4. (606 aa)
BCS1LBCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family. (419 aa)
MCM8MCM domain-containing protein; Belongs to the MCM family. (832 aa)
AFG3L2AFG3 like matrix AAA peptidase subunit 2. (805 aa)
RAD51BRAD51 paralog B. (350 aa)
ABCG4ATP binding cassette subfamily G member 4. (646 aa)
FIGNFidgetin, microtubule severing factor; Belongs to the AAA ATPase family. (785 aa)
ATG9AUncharacterized protein. (1498 aa)
KATNA1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (491 aa)
ABCC5ATP binding cassette subfamily C member 5. (1437 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (440 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
ABCB9ATP binding cassette subfamily B member 9. (770 aa)
FIGNL2Fidgetin like 2. (656 aa)
ABCC3ATP binding cassette subfamily C member 3. (1529 aa)
ABCE1ATP binding cassette subfamily E member 1. (599 aa)
DNAH7Dynein axonemal heavy chain 7. (4023 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
A0A4W2EJE7Uncharacterized protein. (1058 aa)
A0A4W2EJI6Uncharacterized protein. (1304 aa)
ABCC8ATP binding cassette subfamily C member 8. (1529 aa)
NLRC5NLR family CARD domain containing 5. (1862 aa)
TOR3ATorsin family 3 member A. (317 aa)
ABCC11ATP binding cassette subfamily C member 11. (1379 aa)
SPG7SPG7 matrix AAA peptidase subunit, paraplegin. (831 aa)
DNAH2Dynein axonemal heavy chain 2. (4376 aa)
TAP1Transporter 1, ATP binding cassette subfamily B member. (838 aa)
MCM3DNA helicase; Belongs to the MCM family. (808 aa)
LOC113881324Uncharacterized protein. (719 aa)
A0A4W2BUQ1ABC transporter domain-containing protein. (619 aa)
KATNAL2Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (628 aa)
DNAH3Dynein axonemal heavy chain 3. (4069 aa)
VWA8Von Willebrand factor A domain containing 8. (1897 aa)
A0A4W2EZ96Uncharacterized protein. (1258 aa)
ABCC9ATP binding cassette subfamily C member 9. (1549 aa)
ABCG2ATP binding cassette subfamily G member 2 (Junior blood group). (658 aa)
LOC113902483Uncharacterized protein. (1304 aa)
ATAD2ATPase family AAA domain containing 2. (1373 aa)
ABCA10ATP binding cassette subfamily A member 10. (1540 aa)
NLRP2NLR family pyrin domain containing 2. (974 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa)
TOR2ATorsin. (321 aa)
GPN1GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. (385 aa)
SNRNP200Small nuclear ribonucleoprotein U5 subunit 200. (2136 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (462 aa)
ABCA1ATP binding cassette subfamily A member 1. (2261 aa)
ABCB8ATP binding cassette subfamily B member 8. (788 aa)
A0A4W2ETK4Uncharacterized protein. (632 aa)
FIGNL1Fidgetin like 1; Belongs to the AAA ATPase family. (677 aa)
ABCB11ATP binding cassette subfamily B member 11. (1323 aa)
RFC1Replication factor C subunit 1. (1146 aa)
ABCG1ATP binding cassette subfamily G member 1. (679 aa)
ABCB5ATP binding cassette subfamily B member 5. (1256 aa)
ABCA7ATP binding cassette subfamily A member 7. (2152 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4645 aa)
RFC5Replication factor C subunit 5. (527 aa)
MCM9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1139 aa)
NSFN-ethylmaleimide sensitive factor, vesicle fusing ATPase. (797 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (816 aa)
A0A4W2EC47Uncharacterized protein. (1293 aa)
AK9Adenylate kinase 9. (1902 aa)
ASCC3Activating signal cointegrator 1 complex subunit 3. (2201 aa)
A0A4W2EDB4Uncharacterized protein. (1293 aa)
DYNC2H1Dynein cytoplasmic 2 heavy chain 1. (4313 aa)
LOC113888438Uncharacterized protein. (1343 aa)
NAV1Neuron navigator 1. (2221 aa)
ATAD1ATPase family AAA domain containing 1; Belongs to the AAA ATPase family. (361 aa)
ABCC12ATP binding cassette subfamily C member 12. (1360 aa)
RAD17RAD17 checkpoint clamp loader component. (708 aa)
ABCD2ATP binding cassette subfamily D member 2. (741 aa)
NUBP1Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (385 aa)
A0A4W2BKC3Uncharacterized protein. (3952 aa)
RFC3Replication factor C subunit 3. (356 aa)
DNAH1Dynein axonemal heavy chain 1. (4265 aa)
A0A4W2BPB6Uncharacterized protein. (1333 aa)
CHTF18Chromosome transmission fidelity factor 18. (978 aa)
NAV2Neuron navigator 2. (2451 aa)
WRNIP1WRN helicase interacting protein 1. (638 aa)
A0A4W2DCI8Uncharacterized protein. (1318 aa)
ABCA13ATP binding cassette subfamily A member 13. (4916 aa)
DNAH11Dynein axonemal heavy chain 11. (4512 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
ABCF3ATP binding cassette subfamily F member 3. (709 aa)
PEX1Peroxisomal biogenesis factor 1. (1281 aa)
RFC4Replication factor C subunit 4. (364 aa)
NAV3Neuron navigator 3. (2385 aa)
ATAD3AATPase family AAA domain containing 3A. (586 aa)
LONP1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (1027 aa)
ABCD3ATP binding cassette subfamily D member 3. (659 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
Server load: medium (42%) [HD]