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IDH3B IDH3B PDHB PDHB TSR1 TSR1 SUCLG2 SUCLG2 SDHD SDHD DLAT DLAT URB2 URB2 ZMIZ1 ZMIZ1 KIFC3 KIFC3 SUCLG1 SUCLG1 MDH1B MDH1B A0A4W2CSI7 A0A4W2CSI7 OGDH OGDH ACO1 ACO1 A0A4W2D359 A0A4W2D359 OGDHL OGDHL ZMIZ2 ZMIZ2 FH FH SUCLA2 SUCLA2 PPP1R32 PPP1R32 PC PC SDHAF2 SDHAF2 KIFC2 KIFC2 IDH2 IDH2 ACLY ACLY BBS1 BBS1 PCK1 PCK1 KIFC1 KIFC1 ACO2 ACO2 IDH3A IDH3A A0A4W2EPI9 A0A4W2EPI9 PCK2 PCK2 PDHA2 PDHA2 SDHC SDHC MDH1 MDH1 MDH2 MDH2 DLST DLST SDHA SDHA DLD DLD IDH1 IDH1 CS CS SDHB SDHB A0A4W2HUZ1 A0A4W2HUZ1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (385 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (361 aa)
TSR1TSR1 ribosome maturation factor. (804 aa)
SUCLG2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (546 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (184 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (647 aa)
URB2URB2 ribosome biogenesis homolog. (1521 aa)
ZMIZ1Zinc finger MIZ-type containing 1. (1112 aa)
KIFC3Kinesin family member C3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1020 aa)
SUCLG1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (346 aa)
MDH1BMalate dehydrogenase 1B. (527 aa)
A0A4W2CSI7Uncharacterized protein. (147 aa)
OGDHOxoglutarate dehydrogenase. (1045 aa)
ACO1Aconitase 1; Belongs to the aconitase/IPM isomerase family. (897 aa)
A0A4W2D359Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (529 aa)
OGDHLOxoglutarate dehydrogenase like. (1121 aa)
ZMIZ2Zinc finger MIZ-type containing 2. (934 aa)
FHFumarate hydratase. (503 aa)
SUCLA2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (463 aa)
PPP1R32Protein phosphatase 1 regulatory subunit 32. (428 aa)
PCPyruvate carboxylase. (1266 aa)
SDHAF2Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (216 aa)
KIFC2Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (772 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (477 aa)
ACLYATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1101 aa)
BBS1BBS1 domain-containing protein. (667 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (694 aa)
KIFC1Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (670 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (780 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (458 aa)
A0A4W2EPI9Uncharacterized protein. (166 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (820 aa)
PDHA2Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (325 aa)
SDHCUncharacterized protein. (169 aa)
MDH1Malate dehydrogenase. (334 aa)
MDH2Malate dehydrogenase. (338 aa)
DLSTDihydrolipoamide S-succinyltransferase. (529 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
DLDDihydrolipoyl dehydrogenase. (509 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
CSCitrate synthase; Belongs to the citrate synthase family. (466 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (285 aa)
A0A4W2HUZ1Uncharacterized protein. (83 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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