STRINGSTRING
TAT TAT COQ2 COQ2 ZNF410 ZNF410 UBIAD1 UBIAD1 NQO1 NQO1 ITPRIP ITPRIP CCAR2 CCAR2 COQ6 COQ6 PRSS53 PRSS53 COQ3 COQ3 A0A4W2CXF2 A0A4W2CXF2 GGCX GGCX HPD HPD COQ7 COQ7 COQ5 COQ5 HPS4 HPS4 VKORC1 VKORC1 TMEM94 TMEM94 GINS4 GINS4 CCAR1 CCAR1 VKORC1L1 VKORC1L1 NQO2 NQO2 ITPRIPL2 ITPRIPL2 ABHD11 ABHD11 ACOT13 ACOT13 ABHD8 ABHD8 HPDL HPDL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TATTyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (507 aa)
COQ24-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (371 aa)
ZNF410Zinc finger protein 410. (478 aa)
UBIAD1UbiA prenyltransferase domain containing 1. (332 aa)
NQO1NAD(P)H quinone dehydrogenase 1. (274 aa)
ITPRIPInositol 1,4,5-trisphosphate receptor interacting protein. (556 aa)
CCAR2Cell cycle and apoptosis regulator 2. (892 aa)
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (485 aa)
PRSS53Serine protease 53; Belongs to the peptidase S1 family. (553 aa)
COQ3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (383 aa)
A0A4W2CXF24HBT domain-containing protein. (200 aa)
GGCXGamma-glutamyl carboxylase. (809 aa)
HPD4-hydroxyphenylpyruvate dioxygenase. (396 aa)
COQ75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (262 aa)
COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (345 aa)
HPS4HPS4 biogenesis of lysosomal organelles complex 3 subunit 2. (681 aa)
VKORC1VKc domain-containing protein. (92 aa)
TMEM94Transmembrane protein 94. (1539 aa)
GINS4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa)
CCAR1Cell division cycle and apoptosis regulator 1. (1149 aa)
VKORC1L1VKc domain-containing protein. (301 aa)
NQO2N-ribosyldihydronicotinamide:quinone reductase 2. (231 aa)
ITPRIPL2ITPRIP like 2. (532 aa)
ABHD11Abhydrolase domain containing 11. (335 aa)
ACOT13Acyl-CoA thioesterase 13. (155 aa)
ABHD8Abhydrolase domain containing 8. (432 aa)
HPDL4-hydroxyphenylpyruvate dioxygenase like. (404 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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