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| | GMPR | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (345 aa) |
| | ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1117 aa) |
| | A0A4W2BP39 | Uncharacterized protein. (554 aa) |
| | NME3 | Nucleoside diphosphate kinase. (169 aa) |
| | SLC37A2 | Solute carrier family 37 member 2. (505 aa) |
| | AK4 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (223 aa) |
| | FBXL2 | F-box and leucine rich repeat protein 2. (436 aa) |
| | ENTPD8 | Ectonucleoside triphosphate diphosphohydrolase 8; Belongs to the GDA1/CD39 NTPase family. (495 aa) |
| | AK8 | Adenylate kinase 8; Belongs to the adenylate kinase family. (498 aa) |
| | NME6 | Nucleoside diphosphate kinase. (186 aa) |
| | ENPP5 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 5. (477 aa) |
| | ADSL | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (490 aa) |
| | NME1 | Nucleoside diphosphate kinase. (152 aa) |
| | NT5M | 5',3'-nucleotidase, mitochondrial. (223 aa) |
| | A0A4W2C2E5 | Uncharacterized protein. (453 aa) |
| | ENTPD1 | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (564 aa) |
| | ADA2 | Adenosine deaminase 2. (579 aa) |
| | MRPS34 | Mitochondrial ribosomal protein S34. (218 aa) |
| | HELLS | Helicase, lymphoid specific. (837 aa) |
| | ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese dependent. (337 aa) |
| | A0A4W2C435 | AAA_16 domain-containing protein. (1196 aa) |
| | ADSSL1 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (457 aa) |
| | INF2 | Inverted formin, FH2 and WH2 domain containing. (1302 aa) |
| | NUDT11 | Nudix hydrolase 11. (164 aa) |
| | CANT1 | Calcium activated nucleotidase 1. (457 aa) |
| | CC2D2B | Coiled-coil and C2 domain containing 2B. (401 aa) |
| | TAF1C | TATA-box binding protein associated factor, RNA polymerase I subunit C. (1037 aa) |
| | A0A4W2C5U2 | Uncharacterized protein. (85 aa) |
| | SPSB2 | SplA/ryanodine receptor domain and SOCS box containing 2. (263 aa) |
| | HDDC3 | HD domain containing 3. (179 aa) |
| | PRPSAP1 | Phosphoribosyl pyrophosphate synthetase associated protein 1. (385 aa) |
| | PDE6C | Phosphodiesterase. (855 aa) |
| | PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2. (620 aa) |
| | PDE4D | Phosphodiesterase. (806 aa) |
| | AK7 | Adenylate kinase 7. (751 aa) |
| | PDE6G | Phosphodiesterase 6G. (87 aa) |
| | KIAA1614 | KIAA1614. (1405 aa) |
| | PUS1 | Pseudouridine synthase 1. (399 aa) |
| | DALRD3 | DALR anticodon binding domain containing 3. (541 aa) |
| | NT5DC1 | 5'-nucleotidase domain containing 1. (452 aa) |
| | ADK | Adenosine kinase. (362 aa) |
| | ANKRD33B | Ankyrin repeat domain 33B. (488 aa) |
| | CALB2 | Calbindin 2. (279 aa) |
| | TTLL8 | Tubulin tyrosine ligase like 8. (799 aa) |
| | A0A4W2CFG6 | AIRC domain-containing protein. (136 aa) |
| | GUCY1A1 | Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (691 aa) |
| | NPR3 | Natriuretic peptide receptor 3. (537 aa) |
| | NT5E | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (574 aa) |
| | A0A4W2CJ06 | Guanylate cyclase domain-containing protein. (325 aa) |
| | ENTPD7 | Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (604 aa) |
| | PRTFDC1 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (222 aa) |
| | PDE1C | Phosphodiesterase. (769 aa) |
| | A0A4W2CP97 | Uncharacterized protein. (823 aa) |
| | AMPD3 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (784 aa) |
| | NPR2 | Guanylate cyclase. (1041 aa) |
| | PUSL1 | tRNA pseudouridine synthase. (291 aa) |
| | XDH | Xanthine dehydrogenase. (1332 aa) |
| | ENTPD6 | Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. (456 aa) |
| | TET3 | Tet methylcytosine dioxygenase 3. (1792 aa) |
| | DGUOK | Deoxyguanosine kinase. (277 aa) |
| | PDE6D | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...] (150 aa) |
| | AK1 | Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. (230 aa) |
| | PDE7B | Phosphodiesterase. (501 aa) |
| | A0A4W2CSE6 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (216 aa) |
| | HINT2 | Histidine triad nucleotide binding protein 2. (163 aa) |
| | AK3 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (227 aa) |
| | AK6 | Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (270 aa) |
| | ENPP1 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. (940 aa) |
| | AK2 | Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. (234 aa) |
| | DPH6 | Diphthine--ammonia ligase; Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP. (267 aa) |
| | NUDT5 | Nudix hydrolase 5; Belongs to the Nudix hydrolase family. (218 aa) |
| | IMPDH1 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (604 aa) |
| | LOC113900013 | RNAse_Pc domain-containing protein. (471 aa) |
| | LOC113900017 | PNP_UDP_1 domain-containing protein. (96 aa) |
| | ADCY2 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1096 aa) |
| | SLC37A3 | Solute carrier family 37 member 3. (495 aa) |
| | PTRHD1 | Peptidyl-tRNA hydrolase domain containing 1. (140 aa) |
| | ADCY6 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa) |
| | A0A4W2D168 | Uncharacterized protein. (117 aa) |
| | TTLL5 | Tubulin tyrosine ligase like 5. (1331 aa) |
| | GMPR2 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (348 aa) |
| | PDE10A | Phosphodiesterase. (1068 aa) |
| | AMPD2 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (826 aa) |
| | NUDT4 | Nudix hydrolase domain-containing protein. (181 aa) |
| | PDE6B | Phosphodiesterase. (853 aa) |
| | ADA | Adenosine deaminase. (391 aa) |
| | ADCY4 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa) |
| | OLA1 | Obg like ATPase 1. (278 aa) |
| | PPAT | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (539 aa) |
| | ITPA | Uncharacterized protein. (304 aa) |
| | IQCJ | IQ motif containing J. (157 aa) |
| | ZSCAN20 | Zinc finger and SCAN domain containing 20. (1105 aa) |
| | NUDT9 | Nudix hydrolase 9. (349 aa) |
| | GMPS | Guanine monophosphate synthase. (714 aa) |
| | IPO13 | Importin 13. (963 aa) |
| | PRPS1L1 | Phosphoribosyl pyrophosphate synthetase 1 like 1. (318 aa) |
| | PDE4C | Phosphodiesterase. (727 aa) |
| | PGM2 | Phosphoglucomutase 2. (612 aa) |
| | LOC113892965 | SCHIP-1 domain-containing protein. (554 aa) |
| | PGM1 | Phosphoglucomutase 1; Belongs to the phosphohexose mutase family. (580 aa) |
| | MANEAL | Mannosidase endo-alpha like. (455 aa) |
| | PDE9A | Phosphodiesterase. (533 aa) |
| | ADCY10 | Adenylate cyclase 10. (1614 aa) |
| | AK5 | Adenylate kinase 5; Belongs to the adenylate kinase family. (562 aa) |
| | ENTPD5 | Ectonucleoside triphosphate diphosphohydrolase 5 (inactive); Belongs to the GDA1/CD39 NTPase family. (428 aa) |
| | A0A4W2DN71 | Uncharacterized protein. (86 aa) |
| | PDE4A | Phosphodiesterase. (848 aa) |
| | PDE5A | Phosphodiesterase. (865 aa) |
| | ENTPD2 | Ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family. (495 aa) |
| | C25H16orf71 | Uncharacterized protein. (488 aa) |
| | A0A4W2DQF1 | TR_THY domain-containing protein. (128 aa) |
| | PDE8B | Phosphodiesterase. (885 aa) |
| | A0A4W2DRM3 | Uncharacterized protein. (77 aa) |
| | A0A4W2DSL7 | Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (627 aa) |
| | ENPP4 | Ectonucleotide pyrophosphatase/phosphodiesterase 4. (453 aa) |
| | A0A4W2DTS9 | Uncharacterized protein. (104 aa) |
| | ENTPD3 | Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. (529 aa) |
| | GUK1 | Guanylate kinase-like domain-containing protein. (339 aa) |
| | CUTC | CutC copper transporter. (273 aa) |
| | SVOP | SV2 related protein. (548 aa) |
| | ADCY7 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1096 aa) |
| | NUDT16 | Nudix hydrolase 16. (204 aa) |
| | PARP8 | Poly [ADP-ribose] polymerase. (923 aa) |
| | SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1051 aa) |
| | NT5C | 5', 3'-nucleotidase, cytosolic. (208 aa) |
| | ADCY8 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1253 aa) |
| | A0A4W2E3Z8 | Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. (155 aa) |
| | URAD | OHCU_decarbox domain-containing protein. (170 aa) |
| | PFAS | Phosphoribosylformylglycinamidine synthase. (1367 aa) |
| | PUS3 | Pseudouridine synthase 3. (481 aa) |
| | LOC113875399 | TR_THY domain-containing protein. (363 aa) |
| | MPP6 | Membrane palmitoylated protein 6; Belongs to the MAGUK family. (623 aa) |
| | FBXO41 | F-box protein 41. (863 aa) |
| | ADCY1 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1197 aa) |
| | A0A4W2EBF7 | Uncharacterized protein. (1452 aa) |
| | ENPP3 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. (874 aa) |
| | CHML | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. (651 aa) |
| | AK9 | Adenylate kinase 9. (1902 aa) |
| | LRGUK | Leucine rich repeats and guanylate kinase domain containing. (830 aa) |
| | PDE2A | Phosphodiesterase. (943 aa) |
| | RRM2 | Ribonucleotide reductase regulatory subunit M2. (429 aa) |
| | NTPCR | Uncharacterized protein. (271 aa) |
| | LOC113901538 | Uncharacterized protein. (537 aa) |
| | CNNM1 | Cyclin and CBS domain divalent metal cation transport mediator 1. (960 aa) |
| | PDE7A | Phosphodiesterase. (552 aa) |
| | A0A4W2EFU9 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (211 aa) |
| | PDE3B | Phosphodiesterase. (1115 aa) |
| | GUCY2D | Guanylate cyclase. (1108 aa) |
| | A0A4W2EHX5 | HIT domain-containing protein. (99 aa) |
| | PRUNE2 | Prune homolog 2 with BCH domain. (3079 aa) |
| | ADSS | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (456 aa) |
| | TTL | Tubulin tyrosine ligase. (377 aa) |
| | NT5C3B | 5'-nucleotidase, cytosolic IIIB. (200 aa) |
| | PPP1R8 | Protein phosphatase 1 regulatory subunit 8. (351 aa) |
| | ADCY3 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa) |
| | ADCY5 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1259 aa) |
| | PDE1B | Phosphodiesterase. (584 aa) |
| | ALLC | Allantoicase. (412 aa) |
| | PKM | Multifunctional fusion protein; Belongs to the pyruvate kinase family. (926 aa) |
| | CC2D2A | Coiled-coil and C2 domain containing 2A. (1620 aa) |
| | AMPD1 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (773 aa) |
| | CHD1L | Chromodomain helicase DNA binding protein 1 like. (897 aa) |
| | LOC113894312 | Uncharacterized protein. (864 aa) |
| | A0A4W2EW27 | Uncharacterized protein. (63 aa) |
| | DCK | Deoxycytidine kinase. (260 aa) |
| | NT5C1A | 5'-nucleotidase, cytosolic IA. (365 aa) |
| | GUCY2C | Guanylate cyclase. (1072 aa) |
| | PDE3A | Phosphodiesterase. (1126 aa) |
| | NME5 | NME/NM23 family member 5; Belongs to the NDK family. (211 aa) |
| | GART | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1010 aa) |
| | NPR1 | Guanylate cyclase. (1064 aa) |
| | PDE6A | Phosphodiesterase. (859 aa) |
| | SLC37A1 | Solute carrier family 37 member 1. (569 aa) |
| | PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1. (668 aa) |
| | NIT1 | Nitrilase 1. (328 aa) |
| | TET2 | Tet methylcytosine dioxygenase 2. (2007 aa) |
| | FBXL13 | F-box and leucine rich repeat protein 13. (734 aa) |
| | PDE11A | Phosphodiesterase. (926 aa) |
| | TTLL1 | Tubulin tyrosine ligase like 1. (423 aa) |
| | PDE1A | Phosphodiesterase. (544 aa) |
| | A0A4W2FAP4 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa) |
| | GLOD5 | Glyoxalase domain containing 5. (159 aa) |
| | KDM1B | Lysine demethylase 1B. (921 aa) |
| | PDE6H | Phosphodiesterase 6H. (83 aa) |
| | PKLR | Pyruvate kinase; Belongs to the pyruvate kinase family. (574 aa) |
| | RRM2B | Ribonucleotide reductase regulatory TP53 inducible subunit M2B. (351 aa) |
| | HINT3 | Histidine triad nucleotide binding protein 3. (182 aa) |
| | NT5C3A | 5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (331 aa) |
| | PRPSAP2 | Phosphoribosyl pyrophosphate synthetase associated protein 2. (386 aa) |
| | GUCY1B1 | Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa) |
| | GDA | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (454 aa) |
| | ANKRD33 | ANK_REP_REGION domain-containing protein. (267 aa) |
| | PGM5 | Phosphoglucomutase 5; Belongs to the phosphohexose mutase family. (567 aa) |
| | IMPDH2 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (514 aa) |
| | QRICH1 | Glutamine rich 1. (779 aa) |
| | PDE8A | Phosphodiesterase. (832 aa) |
| | TET1 | Tet methylcytosine dioxygenase 1. (2137 aa) |
| | AK4-2 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (223 aa) |
| | ADAL | Adenosine deaminase like. (351 aa) |
| | PDE4B | Phosphodiesterase. (736 aa) |
| | RRM1 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (791 aa) |
| | MPP2 | Membrane palmitoylated protein 2; Belongs to the MAGUK family. (569 aa) |
| | PRUNE1 | Prune exopolyphosphatase 1. (453 aa) |
| | SVOPL | SVOP like. (492 aa) |
| | LOC113889694 | Uncharacterized protein. (360 aa) |
| | FHIT | Bis(5'-adenosyl)-triphosphatase. (149 aa) |
| | SPSB3 | SplA/ryanodine receptor domain and SOCS box containing 3. (373 aa) |
| | NRSN1 | Neurensin 1. (195 aa) |
| | CNNM2 | Cyclin and CBS domain divalent metal cation transport mediator 2. (875 aa) |
| | NT5C2 | 5'-nucleotidase, cytosolic II. (568 aa) |
| | CNNM4 | Cyclin and CBS domain divalent metal cation transport mediator 4. (795 aa) |
| | GUCY1A2 | Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (730 aa) |
| | HINT1 | Histidine triad nucleotide binding protein 1. (126 aa) |
| | NUDT2 | Nudix hydrolase 2; Belongs to the Nudix hydrolase family. (147 aa) |
| | ATIC | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. (592 aa) |
| | ENKUR | Enkurin, TRPC channel interacting protein. (259 aa) |
| | FBXL20 | F-box and leucine rich repeat protein 20. (438 aa) |
| | FBXO45 | F-box protein 45. (281 aa) |
| | SPSB4 | SplA/ryanodine receptor domain and SOCS box containing 4. (273 aa) |
| | A0A4W2IQ09 | Uncharacterized protein. (178 aa) |
