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| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (456 aa) |
| | BCL2 | BCL2 apoptosis regulator. (229 aa) |
| | LOC113882304 | Glutathione S-transferase. (291 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | GSTO2 | Glutathione S-transferase omega 2; Belongs to the GST superfamily. (244 aa) |
| | A0A4W2C102 | Glutathione S-transferase. (222 aa) |
| | MGST2 | Microsomal glutathione S-transferase 2. (155 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) |
| | FAS | Fas cell surface death receptor. (323 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | BAD | BCL2 associated agonist of cell death. (168 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (209 aa) |
| | PMAIP1 | Phorbol-12-myristate-13-acetate-induced protein 1. (54 aa) |
| | A0A4W2CGI4 | Uncharacterized protein. (222 aa) |
| | ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (351 aa) |
| | BIRC3 | Baculoviral IAP repeat containing 3. (604 aa) |
| | GSTO1 | Glutathione S-transferase omega 1; Belongs to the GST superfamily. (344 aa) |
| | A0A4W2CHX7 | BH4_2 domain-containing protein. (233 aa) |
| | AKT2 | AKT serine/threonine kinase 2. (603 aa) |
| | TOP2B | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1619 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (193 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (634 aa) |
| | LOC113907256 | Uncharacterized protein; Belongs to the GST superfamily. (239 aa) |
| | A0A4W2CR94 | Uncharacterized protein; Belongs to the GST superfamily. (322 aa) |
| | C7orf31 | Chromosome 7 open reading frame 31. (584 aa) |
| | XPA | XPA, DNA damage recognition and repair factor. (273 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa) |
| | MDM2 | MDM2 proto-oncogene. (689 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1366 aa) |
| | A0A4W2IDQ2 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (485 aa) |
| | A0A4W2CYF2 | PWWP domain-containing protein. (159 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (452 aa) |
| | A0A4W2D4T7 | Uncharacterized protein. (356 aa) |
| | A0A4W2D608 | BH4_2 domain-containing protein. (238 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (747 aa) |
| | MGST3 | Microsomal glutathione S-transferase 3. (209 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | POLH | DNA polymerase eta. (711 aa) |
| | ATP7B | ATPase copper transporting beta. (1505 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3054 aa) |
| | LOC113888945 | Uncharacterized protein. (623 aa) |
| | A0A4W2DXS4 | RING-type domain-containing protein. (131 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | TOP2A | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1532 aa) |
| | ERBB2 | Erb-b2 receptor tyrosine kinase 2. (1710 aa) |
| | ABCC2 | ATP binding cassette subfamily C member 2. (1543 aa) |
| | MSH3 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1118 aa) |
| | BIRC5 | Baculoviral IAP repeat containing 5. (142 aa) |
| | MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1361 aa) |
| | A0A4W2E8M1 | BH4_2 domain-containing protein. (173 aa) |
| | A0A4W2E9P7 | Uncharacterized protein. (244 aa) |
| | FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (277 aa) |
| | LOC113886404 | GST C-terminal domain-containing protein. (274 aa) |
| | A0A4W2BS34 | Uncharacterized protein. (147 aa) |
| | MLH1 | MutL homolog 1. (758 aa) |
| | AKT3 | AKT serine/threonine kinase 3. (564 aa) |
| | BRCA1 | BRCA1 DNA repair associated. (1941 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (161 aa) |
| | A0A4W2EHH7 | Uncharacterized protein. (91 aa) |
| | REV3L | REV3 like, DNA directed polymerase zeta catalytic subunit. (3133 aa) |
| | GSTM4 | Glutathione S-transferase mu 4. (264 aa) |
| | GSTM3 | Glutathione S-transferase. (257 aa) |
| | LOC113901903 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | PIK3R3 | Uncharacterized protein. (461 aa) |
| | MGST1 | Microsomal glutathione S-transferase 1. (155 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1249 aa) |
| | SLC31A1 | Solute carrier family 31 member 1. (189 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase. (747 aa) |
| | PIK3R2 | Uncharacterized protein. (724 aa) |
| | LOC113891379 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | A0A4W2G4L9 | Uncharacterized protein. (148 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa) |
| | BCL2L1 | BH4_2 domain-containing protein. (233 aa) |
| | BBC3 | Uncharacterized protein. (193 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | A0A4W2H7Y7 | BH4_2 domain-containing protein. (195 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (499 aa) |
