Your Input: | |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa) |
| | A0A4W2HUR1 | HORMA domain-containing protein. (197 aa) |
| | CDK7 | Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa) |
| | WEE1 | Wee1-like protein kinase. (646 aa) |
| | RB1 | RB transcriptional corepressor 1. (928 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (499 aa) |
| | A0A4W2I5C3 | Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (70 aa) |
| | CDK1 | Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa) |
| | A0A4W2I9K4 | Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (58 aa) |
| | CDKN2D | Cyclin dependent kinase inhibitor 2D. (166 aa) |
| | RBX1 | RING-type domain-containing protein. (128 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (607 aa) |
| | FAM126B | Family with sequence similarity 126 member B. (586 aa) |
| | A0A4W2GSS9 | Uncharacterized protein. (47 aa) |
| | YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (268 aa) |
| | E2F3 | E2F transcription factor 3. (465 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (421 aa) |
| | YWHAG | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa) |
| | ZBTB47 | Zinc finger and BTB domain containing 47. (770 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (902 aa) |
| | PLK1 | Serine/threonine-protein kinase PLK. (602 aa) |
| | A0A4W2BS58 | RING-type domain-containing protein. (81 aa) |
| | A0A4W2BSK9 | Uncharacterized protein. (784 aa) |
| | A0A4W2BTG3 | Uncharacterized protein. (65 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (626 aa) |
| | A0A4W2BX47 | Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (79 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (808 aa) |
| | EP300 | E1A binding protein p300. (2411 aa) |
| | ANAPC10 | DOC domain-containing protein. (327 aa) |
| | ZNF652 | Zinc finger protein 652. (608 aa) |
| | A0A4W2C2N7 | E2F_CC-MB domain-containing protein. (178 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa) |
| | ANAPC5 | Anaphase promoting complex subunit 5. (755 aa) |
| | ANAPC11 | RING-type domain-containing protein. (84 aa) |
| | E2F4 | E2F transcription factor 4. (498 aa) |
| | RBL2 | RB transcriptional corepressor like 2. (1140 aa) |
| | E2F5 | E2F_TDP domain-containing protein. (313 aa) |
| | CDC25A | Cell division cycle 25A. (525 aa) |
| | TTK | TTK protein kinase. (924 aa) |
| | CDC27 | Cell division cycle 27. (831 aa) |
| | PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4122 aa) |
| | A0A4W2CFU1 | Protein kinase domain-containing protein. (79 aa) |
| | SMC1B | Structural maintenance of chromosomes protein. (1235 aa) |
| | A0A4W2CGD5 | 14_3_3 domain-containing protein. (110 aa) |
| | TGFB1 | Transforming growth factor beta 1. (443 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (836 aa) |
| | A0A4W2CNN4 | Uncharacterized protein. (207 aa) |
| | ZBTB10 | Zinc finger and BTB domain containing 10. (870 aa) |
| | YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa) |
| | ORC6 | Origin recognition complex subunit 6. (203 aa) |
| | YWHAZ | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (245 aa) |
| | MDM2 | MDM2 proto-oncogene. (689 aa) |
| | ANAPC7 | Anaphase promoting complex subunit 7. (598 aa) |
| | ABL1 | Tyrosine-protein kinase. (1151 aa) |
| | CDC16 | Cell division cycle 16. (620 aa) |
| | SFN | Stratifin; Belongs to the 14-3-3 family. (248 aa) |
| | A0A4W2CWK4 | Skp1_POZ domain-containing protein. (65 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (432 aa) |
| | WEE2 | Wee1-like protein kinase. (566 aa) |
| | ORC2 | Origin recognition complex subunit 2. (577 aa) |
| | ORC3 | Origin recognition complex subunit 3. (713 aa) |
| | FZR1 | Fizzy and cell division cycle 20 related 1. (523 aa) |
| | ANAPC1 | Anaphase promoting complex subunit 1. (1958 aa) |
| | ESPL1 | Extra spindle pole bodies like 1, separase. (2100 aa) |
| | CDC14B | Uncharacterized protein. (552 aa) |
| | CDC26 | Cell division cycle 26. (85 aa) |
| | CDC14A | Cell division cycle 14A. (705 aa) |
| | CDC45 | Cell division cycle 45. (616 aa) |
| | A0A4W2D801 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (274 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (326 aa) |
| | AP5S1 | Adaptor related protein complex 5 subunit sigma 1. (198 aa) |
| | LOC113896623 | Uncharacterized protein. (202 aa) |
| | MYNN | Myoneurin. (609 aa) |
| | A0A4W2DCT4 | Uncharacterized protein. (194 aa) |
| | ANAPC13 | Anaphase promoting complex subunit 13. (74 aa) |
| | CDKN2A | Cyclin dependent kinase inhibitor 2A. (160 aa) |
| | PTTG1 | Uncharacterized protein. (202 aa) |
| | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase. (1081 aa) |
| | CDC25C | Cell division cycle 25C. (477 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa) |
| | DBF4 | DBF4 zinc finger. (674 aa) |
| | MAD2L1 | HORMA domain-containing protein. (215 aa) |
| | CCNH | Cyclin H; Belongs to the cyclin family. (329 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (859 aa) |
| | CREBBP | CREB binding protein. (2435 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | A0A4W2DLG1 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (243 aa) |
| | GADD45B | Growth arrest and DNA damage inducible beta. (160 aa) |
| | ANAPC2 | Anaphase promoting complex subunit 2; Belongs to the cullin family. (888 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (553 aa) |
| | CHEK1 | Checkpoint kinase 1. (677 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3054 aa) |
| | BUB3 | BUB3 mitotic checkpoint protein. (343 aa) |
| | CDC23 | Cell division cycle 23. (607 aa) |
| | A0A4W2DXK0 | HORMA domain-containing protein. (258 aa) |
| | A0A4W2DXS4 | RING-type domain-containing protein. (131 aa) |
| | MAD1L1 | Mitotic arrest deficient 1 like 1. (768 aa) |
| | CHEK2 | Checkpoint kinase 2. (534 aa) |
| | CCNB1 | Cyclin B1; Belongs to the cyclin family. (427 aa) |
| | CDC20B | Cell division cycle 20B. (514 aa) |
| | ZBTB17 | Zinc finger and BTB domain containing 17. (947 aa) |
| | MAD2L2 | Mitotic arrest deficient 2 like 2. (211 aa) |
| | CDC25B | Cell division cycle 25B. (574 aa) |
| | TFDP1 | Transcription factor. (410 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (428 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (411 aa) |
| | HDAC1 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (513 aa) |
| | TMEM82 | Transmembrane protein 82. (372 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (161 aa) |
| | CCND3 | Cyclin D3; Belongs to the cyclin family. (292 aa) |
| | CCNB2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (398 aa) |
| | A0A4W2EHH7 | Uncharacterized protein. (91 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) |
| | CDK4 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (303 aa) |
| | ZBTB46 | Zinc finger and BTB domain containing 46. (614 aa) |
| | BUB1B | Uncharacterized protein. (1062 aa) |
| | CDC7 | Cell division cycle 7. (576 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (452 aa) |
| | CDK20 | Uncharacterized protein. (718 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | A0A4W2F1Y8 | CYCLIN domain-containing protein; Belongs to the cyclin family. (250 aa) |
| | A0A4W2F2V9 | Uncharacterized protein. (63 aa) |
| | GADD45A | Growth arrest and DNA damage inducible alpha. (165 aa) |
| | TFDP2 | Transcription factor Dp-2. (451 aa) |
| | SKP2 | F-box domain-containing protein. (436 aa) |
| | PKMYT1 | Protein kinase, membrane associated tyrosine/threonine 1; Belongs to the protein kinase superfamily. (497 aa) |
| | SNAPIN | SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa) |
| | SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | A0A4W2FLF9 | RING-type domain-containing protein. (108 aa) |
| | RBL1 | RB transcriptional corepressor like 1. (1068 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (809 aa) |
| | CNTD2 | Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (332 aa) |
| | SMC3 | Structural maintenance of chromosomes protein. (1217 aa) |
| | RAD21 | RAD21 cohesin complex component. (630 aa) |
| | A0A4W2G5Q0 | Protein kinase domain-containing protein. (79 aa) |
| | A0A4W2GF22 | DOC domain-containing protein. (83 aa) |
| | YWHAQ | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (421 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) |
| | LOC113899187 | Uncharacterized protein. (202 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (892 aa) |
| | RAD21L1 | RAD21 cohesin complex component like 1. (555 aa) |
| | CDKN1C | Uncharacterized protein. (438 aa) |
| | CDKN2B | Cyclin dependent kinase inhibitor 2B. (138 aa) |
| | STAG1 | Stromal antigen 1. (1324 aa) |
| | ORC5 | Origin recognition complex subunit 5. (446 aa) |
| | CCNA2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (430 aa) |
| | E2F1 | E2F transcription factor 1. (437 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | E2F2 | E2F transcription factor 2. (437 aa) |
| | YWHAH | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | CDC20 | Cell division cycle 20. (499 aa) |
| | HDAC2 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | SMC1A | Structural maintenance of chromosomes protein. (1233 aa) |
| | CDKN2C | Cyclin dependent kinase inhibitor 2C. (168 aa) |
