STRINGSTRING
CNPY3 CNPY3 TLE1 TLE1 JAG1 JAG1 RBPJ RBPJ RBPJL RBPJL APH1B APH1B HDAC2 HDAC2 DTX2 DTX2 HEY1 HEY1 PTPRA PTPRA ADAM17 ADAM17 DTX1 DTX1 PSEN2 PSEN2 TLE3 TLE3 EP300 EP300 PTPRE PTPRE A0A4W2C4K4 A0A4W2C4K4 CTBP2 CTBP2 ATXN1 ATXN1 JAG2 JAG2 RFNG RFNG DVL2 DVL2 HEY2 HEY2 NCOA7 NCOA7 PSENEN PSENEN DLL3 DLL3 DTX4 DTX4 DVL1 DVL1 HES5 HES5 BPTF BPTF DLL4 DLL4 ATXN1L ATXN1L DLL1 DLL1 MUC4 MUC4 TLE2 TLE2 TLE6 TLE6 NUMB NUMB TLE5 TLE5 HEYL HEYL APH1A APH1A NOTCH3 NOTCH3 MFNG MFNG NCSTN NCSTN CREBBP CREBBP HES1 HES1 MAML2 MAML2 NOTCH1 NOTCH1 MAML3 MAML3 KAT2B KAT2B MAML1 MAML1 CIR1 CIR1 NOTCH2 NOTCH2 DVL3 DVL3 PSEN1 PSEN1 SNW1 SNW1 CTBP1 CTBP1 DTX3L DTX3L OXR1 OXR1 MINDY3 MINDY3 NUMBL NUMBL HDAC1 HDAC1 TLE4 TLE4 DTX3 DTX3 NCOR2 NCOR2 LFNG LFNG KAT2A KAT2A NOTCH4 NOTCH4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CNPY3Canopy FGF signaling regulator 3. (276 aa)
TLE1TLE family member 1, transcriptional corepressor. (770 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (500 aa)
RBPJLRecombination signal binding protein for immunoglobulin kappa J region like. (517 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
HDAC2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa)
DTX2Deltex E3 ubiquitin ligase 2. (619 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (308 aa)
PTPRAReceptor-type tyrosine-protein phosphatase alpha. (813 aa)
ADAM17ADAM metallopeptidase domain 17. (825 aa)
DTX1Deltex E3 ubiquitin ligase 1. (619 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (449 aa)
TLE3TLE family member 3, transcriptional corepressor. (772 aa)
EP300E1A binding protein p300. (2411 aa)
PTPREProtein tyrosine phosphatase receptor type E. (724 aa)
A0A4W2C4K4Uncharacterized protein. (336 aa)
CTBP2C-terminal binding protein 2. (972 aa)
ATXN1Ataxin 1. (846 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1239 aa)
RFNGBeta-1,3-N-acetylglucosaminyltransferase. (336 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
NCOA7Nuclear receptor coactivator 7. (952 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
DLL3Delta like canonical Notch ligand 3. (645 aa)
DTX4Deltex E3 ubiquitin ligase 4. (671 aa)
DVL1Dishevelled segment polarity protein 1. (708 aa)
HES5Hes family bHLH transcription factor 5. (227 aa)
BPTFBromodomain PHD finger transcription factor. (3194 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
ATXN1LAtaxin 1 like. (687 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (722 aa)
MUC4Uncharacterized protein. (1175 aa)
TLE2TLE family member 2, transcriptional corepressor. (883 aa)
TLE6TLE family member 6, subcortical maternal complex member. (575 aa)
NUMBNUMB endocytic adaptor protein. (642 aa)
TLE5TLE family member 5, transcriptional modulator. (379 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (329 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
NOTCH3Notch receptor 3. (2313 aa)
MFNGBeta-1,3-N-acetylglucosaminyltransferase. (320 aa)
NCSTNNicastrin. (773 aa)
CREBBPCREB binding protein. (2435 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
MAML2Mastermind like transcriptional coactivator 2. (1127 aa)
NOTCH1Notch receptor 1. (2533 aa)
MAML3Mastermind like transcriptional coactivator 3. (1113 aa)
KAT2BLysine acetyltransferase 2B. (990 aa)
MAML1Mastermind like transcriptional coactivator 1. (1013 aa)
CIR1Corepressor interacting with RBPJ, 1. (412 aa)
NOTCH2Notch receptor 2. (2471 aa)
DVL3Dishevelled segment polarity protein 3. (718 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (478 aa)
SNW1SNW domain containing 1. (536 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (441 aa)
DTX3LDeltex E3 ubiquitin ligase 3L. (739 aa)
OXR1Oxidation resistance 1. (925 aa)
MINDY3MINDY lysine 48 deubiquitinase 3. (445 aa)
NUMBLNUMB like endocytic adaptor protein. (596 aa)
HDAC1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (513 aa)
TLE4TLE family member 4, transcriptional corepressor. (772 aa)
DTX3Deltex E3 ubiquitin ligase 3. (383 aa)
NCOR2Nuclear receptor corepressor 2. (2101 aa)
LFNGBeta-1,3-N-acetylglucosaminyltransferase. (380 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
NOTCH4Notch receptor 4. (1992 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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