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| | CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (373 aa) |
| | A0A4W2DGZ7 | BPI1 domain-containing protein. (286 aa) |
| | CD86 | CD86 molecule. (338 aa) |
| | IFNAR2 | Uncharacterized protein. (530 aa) |
| | IFNAR1 | Interferon alpha and beta receptor subunit 1. (561 aa) |
| | SPP1 | Secreted phosphoprotein 1. (338 aa) |
| | A0A4W2DJH4 | Uncharacterized protein. (189 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | CCL5 | C-C motif chemokine. (91 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | A0A4W2DQY6 | C-X-C motif chemokine. (138 aa) |
| | IRF7 | Interferon regulatory factor 7. (480 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (455 aa) |
| | A0A4W2DUT8 | TIR domain-containing protein. (408 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | BPIFC | BPI fold containing family C. (560 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (505 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (327 aa) |
| | STAT1 | Signal transducer and activator of transcription. (821 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | A0A4W2E7C9 | TNF receptor-associated factor. (411 aa) |
| | A0A4W2E842 | C-C motif chemokine. (93 aa) |
| | CD40 | CD40 molecule. (280 aa) |
| | AKT3 | AKT serine/threonine kinase 3. (564 aa) |
| | MAP2K3 | Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (333 aa) |
| | LY96 | Lymphocyte antigen 96. (160 aa) |
| | TLR5 | Toll like receptor 5; Belongs to the Toll-like receptor family. (858 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (266 aa) |
| | LOC113897812 | Uncharacterized protein. (186 aa) |
| | A0A4W2EML2 | Uncharacterized protein. (186 aa) |
| | A0A4W2EML3 | Uncharacterized protein. (189 aa) |
| | A0A4W2EMM2 | Uncharacterized protein. (187 aa) |
| | CD80 | CD80 molecule. (296 aa) |
| | A0A4W2EMW3 | Uncharacterized protein. (194 aa) |
| | BPI | Bactericidal permeability increasing protein. (522 aa) |
| | TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (759 aa) |
| | CXCL10 | C-X-C motif chemokine. (102 aa) |
| | CXCL11 | C-X-C motif chemokine. (100 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (240 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | TLR6 | Toll-like receptor. (796 aa) |
| | PIK3R3 | Uncharacterized protein. (461 aa) |
| | IL6 | Interleukin 6. (208 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | A0A4W2FDM7 | TIR domain-containing protein. (1029 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (774 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase. (747 aa) |
| | PIK3R2 | Uncharacterized protein. (724 aa) |
| | MAP2K2 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (447 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (425 aa) |
| | LOC113899224 | Toll like receptor adaptor molecule 2. (232 aa) |
| | LOC113899224-2 | GOLD domain-containing protein. (225 aa) |
| | LOC113878185 | C-C motif chemokine. (92 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | CXCL9 | C-X-C motif chemokine. (125 aa) |
| | LOC113897811 | Uncharacterized protein. (186 aa) |
| | LOC113897795 | Uncharacterized protein. (189 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (669 aa) |
| | A0A4W2GYG4 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (379 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (658 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (335 aa) |
| | LOC113878239 | C-C motif chemokine. (89 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (974 aa) |
| | MYD88 | MYD88 innate immune signal transduction adaptor. (384 aa) |
| | IRF6 | Interferon regulatory factor 6. (589 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (456 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (461 aa) |
| | LOC113896989 | Uncharacterized protein. (186 aa) |
| | NFKBIA | NFKB inhibitor alpha. (314 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (485 aa) |
| | LOC113888607 | Uncharacterized protein. (189 aa) |
| | A0A4W2BK72 | Uncharacterized protein. (172 aa) |
| | TOLLIP | Toll interacting protein. (424 aa) |
| | A0A4W2BQS2 | C-C motif chemokine. (87 aa) |
| | A0A4W2BQT6 | SCY domain-containing protein. (170 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (918 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | TLR2 | Toll like receptor 2; Belongs to the Toll-like receptor family. (861 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (412 aa) |
| | TIRAP | TIR domain containing adaptor protein. (327 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | TMED3 | Transmembrane p24 trafficking protein 3. (254 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (209 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (367 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | AKT2 | AKT serine/threonine kinase 2. (603 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (718 aa) |
| | MAP3K8 | Mitogen-activated protein kinase kinase kinase 8. (477 aa) |
| | IRF3 | Interferon regulatory factor 3. (417 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (634 aa) |
| | A0A4W2CR26 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | A0A4W2CWS2 | Uncharacterized protein. (154 aa) |
| | A0A4W2CWV7 | Uncharacterized protein. (189 aa) |
| | A0A4W2CX00 | Uncharacterized protein. (189 aa) |
| | IRF5 | Interferon regulatory factor 5. (499 aa) |
| | A0A4W2D155 | Uncharacterized protein. (153 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (841 aa) |
| | MAP2K1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | CTSK | Cathepsin K; Belongs to the peptidase C1 family. (334 aa) |
| | TLR10 | Toll like receptor 10; Belongs to the Toll-like receptor family. (761 aa) |
| | A0A4W2DGC7 | Uncharacterized protein. (186 aa) |
