STRINGSTRING
BUB1 BUB1 CDC25C CDC25C MAD2L1 MAD2L1 GNAI1 GNAI1 KIF22 KIF22 ANAPC2 ANAPC2 PIK3CA PIK3CA MAPK13 MAPK13 CDC23 CDC23 A0A4W2DXK0 A0A4W2DXK0 KRAS KRAS PIK3CB PIK3CB MAD1L1 MAD1L1 A0A4W2DYS6 A0A4W2DYS6 ADCY7 ADCY7 PGR PGR CPEB4 CPEB4 CPEB3 CPEB3 ADCY8 ADCY8 AURKB AURKB CCNB1 CCNB1 ADCY1 ADCY1 MAD2L2 MAD2L2 CDC25B CDC25B AKT3 AKT3 TMEM82 TMEM82 PDE3B PDE3B CCNB2 CCNB2 REM1 REM1 STK10 STK10 ADCY3 ADCY3 RPS6KA2 RPS6KA2 ADCY5 ADCY5 BRAF BRAF GNAI3 GNAI3 CPEB2 CPEB2 PIK3R3 PIK3R3 A0A4W2F1Y8 A0A4W2F1Y8 MAPK9 MAPK9 PKMYT1 PKMYT1 RPS6KA1 RPS6KA1 GNAI2 GNAI2 LOC113875854 LOC113875854 AKT1 AKT1 PIK3R2 PIK3R2 ANAPC4 ANAPC4 CNTD2 CNTD2 SPDYC SPDYC MAPK10 MAPK10 PRKACA PRKACA A0A4W2GF22 A0A4W2GF22 AURKC AURKC A0A4W2GYG4 A0A4W2GYG4 PRKACB PRKACB CCNA2 CCNA2 CDK2 CDK2 A0A4W2HUR1 A0A4W2HUR1 IGF1 IGF1 CDK1 CDK1 MAPK3 MAPK3 MOS MOS IGF1R IGF1R CCNA1 CCNA1 A0A4W2BND6 A0A4W2BND6 ADCY9 ADCY9 PLK1 PLK1 A0A4W2BS58 A0A4W2BS58 RAF1 RAF1 A0A4W2BSK9 A0A4W2BSK9 A0A4W2BTG3 A0A4W2BTG3 MAPK11 MAPK11 ANAPC10 ANAPC10 A0A4W2C5I5 A0A4W2C5I5 A0A4W2C5N1 A0A4W2C5N1 CDK3 CDK3 HSP90AA1 HSP90AA1 PIK3R1 PIK3R1 ANAPC5 ANAPC5 ANAPC11 ANAPC11 CDC25A CDC25A GEM GEM CDC27 CDC27 MAPK12 MAPK12 AKT2 AKT2 MAPK1 MAPK1 PIK3CD PIK3CD ANAPC7 ANAPC7 CDC16 CDC16 RRAD RRAD SPDYA SPDYA ADCY2 ADCY2 A0A4W2CZ95 A0A4W2CZ95 PTRHD1 PTRHD1 ADCY6 ADCY6 FZR1 FZR1 ANAPC1 ANAPC1 MAP2K1 MAP2K1 MAPK8 MAPK8 CDC26 CDC26 ADCY4 ADCY4 A0A4W2D801 A0A4W2D801 AP5S1 AP5S1 AURKA AURKA ANAPC13 ANAPC13
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1081 aa)
CDC25CCell division cycle 25C. (477 aa)
MAD2L1HORMA domain-containing protein. (215 aa)
GNAI1G protein subunit alpha i1. (417 aa)
KIF22Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (792 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (888 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
MAPK13Mitogen-activated protein kinase. (455 aa)
CDC23Cell division cycle 23. (607 aa)
A0A4W2DXK0HORMA domain-containing protein. (258 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (768 aa)
A0A4W2DYS6Uncharacterized protein. (227 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1096 aa)
PGRProgesterone receptor. (921 aa)
CPEB4Cytoplasmic polyadenylation element binding protein 4. (729 aa)
CPEB3Cytoplasmic polyadenylation element binding protein 3. (714 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1253 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (406 aa)
CCNB1Cyclin B1; Belongs to the cyclin family. (427 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1197 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (211 aa)
CDC25BCell division cycle 25B. (574 aa)
AKT3AKT serine/threonine kinase 3. (564 aa)
TMEM82Transmembrane protein 82. (372 aa)
PDE3BPhosphodiesterase. (1115 aa)
CCNB2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (398 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
STK10Serine/threonine kinase 10. (967 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
RPS6KA2Ribosomal protein S6 kinase. (759 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1259 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (805 aa)
GNAI3G protein subunit alpha i3. (354 aa)
CPEB2Cytoplasmic polyadenylation element binding protein 2. (1039 aa)
PIK3R3Uncharacterized protein. (461 aa)
A0A4W2F1Y8CYCLIN domain-containing protein; Belongs to the cyclin family. (250 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
PKMYT1Protein kinase, membrane associated tyrosine/threonine 1; Belongs to the protein kinase superfamily. (497 aa)
RPS6KA1Ribosomal protein S6 kinase. (844 aa)
GNAI2G protein subunit alpha i2. (436 aa)
LOC113875854Protein kinase domain-containing protein. (258 aa)
AKT1Non-specific serine/threonine protein kinase. (747 aa)
PIK3R2Uncharacterized protein. (724 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (809 aa)
CNTD2Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (332 aa)
SPDYCSpeedy/RINGO cell cycle regulator family member C. (282 aa)
MAPK10Mitogen-activated protein kinase. (425 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
A0A4W2GF22DOC domain-containing protein. (83 aa)
AURKCProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (326 aa)
A0A4W2GYG4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (379 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (367 aa)
CCNA2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (430 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
A0A4W2HUR1HORMA domain-containing protein. (197 aa)
IGF1Insulin like growth factor 1. (188 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (456 aa)
MOSMOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (340 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (421 aa)
A0A4W2BND6IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (100 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1117 aa)
PLK1Serine/threonine-protein kinase PLK. (602 aa)
A0A4W2BS58RING-type domain-containing protein. (81 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
A0A4W2BSK9Uncharacterized protein. (784 aa)
A0A4W2BTG3Uncharacterized protein. (65 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
ANAPC10DOC domain-containing protein. (327 aa)
A0A4W2C5I5Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (104 aa)
A0A4W2C5N1Uncharacterized protein. (603 aa)
CDK3Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (774 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ANAPC5Anaphase promoting complex subunit 5. (755 aa)
ANAPC11RING-type domain-containing protein. (84 aa)
CDC25ACell division cycle 25A. (525 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (311 aa)
CDC27Cell division cycle 27. (831 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
AKT2AKT serine/threonine kinase 2. (603 aa)
MAPK1Mitogen-activated protein kinase. (634 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
ANAPC7Anaphase promoting complex subunit 7. (598 aa)
CDC16Cell division cycle 16. (620 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
SPDYASpeedy/RINGO cell cycle regulator family member A. (312 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1096 aa)
A0A4W2CZ95Uncharacterized protein. (506 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
FZR1Fizzy and cell division cycle 20 related 1. (523 aa)
ANAPC1Anaphase promoting complex subunit 1. (1958 aa)
MAP2K1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
CDC26Cell division cycle 26. (85 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
A0A4W2D801Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (274 aa)
AP5S1Adaptor related protein complex 5 subunit sigma 1. (198 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (402 aa)
ANAPC13Anaphase promoting complex subunit 13. (74 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
Server load: low (32%) [HD]