64 items (Bos indicus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A4W2BQA9	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (176 aa)
	A0A4W2BT40	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (292 aa)
	LTF	Lactotransferrin; Belongs to the transferrin family. (726 aa)
	HEPH	Hephaestin; Belongs to the multicopper oxidase family. (1157 aa)
	FXYD2	FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (179 aa)
	CELSR3	Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family. (3303 aa)
	FTL	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (175 aa)
	LOC113876840	Uncharacterized protein; Belongs to the metallothionein superfamily. Type 1 family. (181 aa)
	SLC26A6	Solute carrier family 26 member 6. (763 aa)
	SLC6A19	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (634 aa)
	SLC26A9	Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (805 aa)
	SLC9A3	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (835 aa)
	SLC5A4	Solute carrier family 5 member 4; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (660 aa)
	SLC8A1	Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
	STEAP1	Ferric oxidoreductase domain-containing protein. (339 aa)
	TRPM7	Transient receptor potential cation channel subfamily M member 7. (1866 aa)
	ATP1B1	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
	TRPM6	Transient receptor potential cation channel subfamily M member 6. (2034 aa)
	STEAP2	STEAP2 metalloreductase. (490 aa)
	ATP2B1	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
	SLC34A1	Solute carrier family 34 member 1. (671 aa)
	SLC34A2	Solute carrier family 34 member 2. (711 aa)
	A0A4W2DEN7	Uncharacterized protein. (913 aa)
	A0A4W2DFR9	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (157 aa)
	ATOX1	HMA domain-containing protein. (68 aa)
	SLC40A1	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (574 aa)
	SLC26A3	Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (760 aa)
	HMOX1	Heme oxygenase 1. (302 aa)
	CLCN2	Chloride channel protein. (911 aa)
	ATP7B	ATPase copper transporting beta. (1505 aa)
	PGPEP1	Pyroglutamyl-peptidase I. (380 aa)
	SLC34A3	Solute carrier family 34 member 3. (602 aa)
	SLC5A1	Solute carrier family 5 member 1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (664 aa)
	SLC39A4	Solute carrier family 39 member 4. (653 aa)
	ATP2B4	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1207 aa)
	SLC8A2	Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (922 aa)
	A0A4W2E8A6	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (190 aa)
	A0A4W2E8F8	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (59 aa)
	A0A4W2E8M6	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (226 aa)
	ATP2B2	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
	VDR	Vitamin D receptor. (425 aa)
	A0A4W2EKS4	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (316 aa)
	A0A4W2EN75	Uncharacterized protein. (627 aa)
	A0A4W2ENJ9	Uncharacterized protein. (456 aa)
	A0A4W2EYK2	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (175 aa)
	A0A4W2F049	Uncharacterized protein; Belongs to the transferrin family. (708 aa)
	ATP1B3	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
	TRPV6	Transient receptor potential cation channel subfamily V member 6; Belongs to the transient receptor (TC 1.A.4) family. (761 aa)
	SLC31A1	Solute carrier family 31 member 1. (189 aa)
	LOC113876838	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
	MT1B	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
	SLC46A1	Solute carrier family 46 member 1. (459 aa)
	ATP1A4	Sodium/potassium-transporting ATPase subunit alpha. (1030 aa)
	ATP1A3	Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
	ATP1A2	Sodium/potassium-transporting ATPase subunit alpha. (1048 aa)
	ATP1A1	Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
	SLC30A1	Solute carrier family 30 member 1. (506 aa)
	A0A4W2H3R6	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
	A0A4W2H7T2	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (91 aa)
	HMOX2	Heme oxygenase 2. (334 aa)
	SLC9A5	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (900 aa)
	ATP1B2	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
	CYBRD1	Cytochrome b reductase 1. (285 aa)
	SLC8A3	Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (928 aa)

Your Current Organism:

Bos indicus

NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A4W2BT40	A0A4W2DFR9	A0A4W2BT40	A0A4W2DFR9	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.790
A0A4W2BT40	A0A4W2EYK2	A0A4W2BT40	A0A4W2EYK2	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.791
A0A4W2BT40	FTL	A0A4W2BT40	A0A4W2C7K9	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.791
A0A4W2BT40	HMOX1	A0A4W2BT40	A0A4W2DL98	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Heme oxygenase 1.	0.406
A0A4W2BT40	SLC40A1	A0A4W2BT40	A0A4W2DIP8	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.	0.424
A0A4W2DEN7	A0A4W2F049	A0A4W2DEN7	A0A4W2F049	Uncharacterized protein.	Uncharacterized protein; Belongs to the transferrin family.	0.905
A0A4W2DFR9	A0A4W2BT40	A0A4W2DFR9	A0A4W2BT40	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.790
A0A4W2DFR9	A0A4W2E8A6	A0A4W2DFR9	A0A4W2E8A6	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.876
A0A4W2DFR9	A0A4W2H7T2	A0A4W2DFR9	A0A4W2H7T2	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.797
A0A4W2E8A6	A0A4W2DFR9	A0A4W2E8A6	A0A4W2DFR9	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.876
A0A4W2E8A6	A0A4W2EYK2	A0A4W2E8A6	A0A4W2EYK2	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.792
A0A4W2E8A6	FTL	A0A4W2E8A6	A0A4W2C7K9	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.876
A0A4W2E8A6	HEPH	A0A4W2E8A6	A0A4W2BTR4	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Hephaestin; Belongs to the multicopper oxidase family.	0.491
A0A4W2E8A6	HMOX1	A0A4W2E8A6	A0A4W2DL98	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Heme oxygenase 1.	0.537
A0A4W2E8A6	SLC40A1	A0A4W2E8A6	A0A4W2DIP8	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.	0.578
A0A4W2E8F8	A0A4W2H3R6	A0A4W2E8F8	A0A4W2H3R6	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.919
A0A4W2E8F8	LOC113876840	A0A4W2E8F8	A0A4W2C8K5	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Uncharacterized protein; Belongs to the metallothionein superfamily. Type 1 family.	0.771
A0A4W2E8F8	MT1B	A0A4W2E8F8	A0A4W2G2F0	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.919
A0A4W2E8M6	A0A4W2EKS4	A0A4W2E8M6	A0A4W2EKS4	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	0.949
A0A4W2EKS4	A0A4W2E8M6	A0A4W2EKS4	A0A4W2E8M6	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	0.949

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