STRINGSTRING
GNG13 GNG13 ADCY6 ADCY6 GABRG2 GABRG2 CACNA1B CACNA1B GRK6 GRK6 PRKCB PRKCB GRK2 GRK2 KCNJ6 KCNJ6 GABRA2 GABRA2 GRK3 GRK3 KCNJ5 KCNJ5 GNG5 GNG5 ARR3 ARR3 PRKACB PRKACB GABRG3 GABRG3 GABRA1 GABRA1 PDE4B PDE4B PRKCA PRKCA PRKACA PRKACA DRD1 DRD1 PDE8A PDE8A GNG7 GNG7 GNG11 GNG11 SLC32A1 SLC32A1 GABRG1 GABRG1 GABRA4 GABRA4 GNAI2 GNAI2 GRK4 GRK4 PDE1A PDE1A PDE11A PDE11A GABRR3 GABRR3 GABRB2 GABRB2 A0A4W2F2N7 A0A4W2F2N7 GABRA6 GABRA6 KCNJ9 KCNJ9 KCNJ3 KCNJ3 PDE3A PDE3A GNB4 GNB4 GNAI3 GNAI3 PDE1B PDE1B ADCY5 ADCY5 ADCY3 ADCY3 ADORA1 ADORA1 ARRB1 ARRB1 PDE3B PDE3B PDE7A PDE7A PDE2A PDE2A PRKCG PRKCG ADCY1 ADCY1 GNB1 GNB1 ARRB2 ARRB2 GNG8 GNG8 GNB3 GNB3 ADCY8 ADCY8 GABRB3 GABRB3 GABRA5 GABRA5 ADCY7 ADCY7 A0A4W2DUV7 A0A4W2DUV7 PDE8B PDE8B PDE4A PDE4A GNAI1 GNAI1 A0A4W2DLH5 A0A4W2DLH5 A0A4W2DHH5 A0A4W2DHH5 CACNA1A CACNA1A A0A4W2DC91 A0A4W2DC91 PDE4C PDE4C GABRB1 GABRB1 GNGT1 GNGT1 ADCY4 ADCY4 GNG10 GNG10 PDE10A PDE10A PTRHD1 PTRHD1 ADCY2 ADCY2 GNAS GNAS OPRM1 OPRM1 GNB5 GNB5 GNG2 GNG2 PDE7B PDE7B GABBR2 GABBR2 GABRD GABRD PDE1C PDE1C GABRR2 GABRR2 GABRP GABRP PDE4D PDE4D GNAO1 GNAO1 A0A4W2C6F2 A0A4W2C6F2 GABBR1 GABBR1 GRK5 GRK5 GNG4 GNG4 GNG3 GNG3 GNB2 GNB2 ADCY9 ADCY9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNG13G protein subunit gamma 13. (67 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
GABRG2Gamma-aminobutyric acid type A receptor gamma2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (475 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2332 aa)
GRK6G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (628 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (689 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (423 aa)
GABRA2Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (511 aa)
GRK3G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (688 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ARR3Arrestin 3. (389 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (367 aa)
GABRG3Gamma-aminobutyric acid type A receptor gamma3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (467 aa)
GABRA1Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (471 aa)
PDE4BPhosphodiesterase. (736 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
PDE8APhosphodiesterase. (832 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
SLC32A1Solute carrier family 32 member 1. (526 aa)
GABRG1Gamma-aminobutyric acid type A receptor gamma1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (465 aa)
GABRA4Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (555 aa)
GNAI2G protein subunit alpha i2. (436 aa)
GRK4G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (577 aa)
PDE1APhosphodiesterase. (544 aa)
PDE11APhosphodiesterase. (926 aa)
GABRR3Gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene); Belongs to the ligand-gated ion channel (TC 1.A.9) family. (468 aa)
GABRB2Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
A0A4W2F2N7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (198 aa)
GABRA6Gamma-aminobutyric acid type A receptor alpha6 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (453 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (434 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
PDE3APhosphodiesterase. (1126 aa)
GNB4G protein subunit beta 4. (340 aa)
GNAI3G protein subunit alpha i3. (354 aa)
PDE1BPhosphodiesterase. (584 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1259 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
ADORA1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
ARRB1Arrestin beta 1. (513 aa)
PDE3BPhosphodiesterase. (1115 aa)
PDE7APhosphodiesterase. (552 aa)
PDE2APhosphodiesterase. (943 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (771 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1197 aa)
GNB1G protein subunit beta 1. (358 aa)
ARRB2Arrestin beta 2. (409 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GNB3G protein subunit beta 3. (356 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1253 aa)
GABRB3Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (498 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1096 aa)
A0A4W2DUV7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (87 aa)
PDE8BPhosphodiesterase. (885 aa)
PDE4APhosphodiesterase. (848 aa)
GNAI1G protein subunit alpha i1. (417 aa)
A0A4W2DLH5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (103 aa)
A0A4W2DHH5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2502 aa)
A0A4W2DC91Uncharacterized protein. (241 aa)
PDE4CPhosphodiesterase. (727 aa)
GABRB1Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (134 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PDE10APhosphodiesterase. (1068 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1096 aa)
GNASGNAS complex locus. (1004 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (419 aa)
GNB5G protein subunit beta 5. (452 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (123 aa)
PDE7BPhosphodiesterase. (501 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (941 aa)
GABRDGamma-aminobutyric acid type A receptor delta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (507 aa)
PDE1CPhosphodiesterase. (769 aa)
GABRR2Gamma-aminobutyric acid type A receptor rho2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (484 aa)
GABRPGamma-aminobutyric acid type A receptor pi subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (440 aa)
PDE4DPhosphodiesterase. (806 aa)
GNAO1G protein subunit alpha o1. (377 aa)
A0A4W2C6F2Sushi domain-containing protein. (231 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (843 aa)
GRK5G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (622 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNB2G protein subunit beta 2. (340 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1117 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.