STRINGSTRING
A0A4W2E9C1 A0A4W2E9C1 RALA RALA AKT3 AKT3 RAB5C RAB5C ARPC5L ARPC5L ABI1 ABI1 VPS11 VPS11 PFN4 PFN4 PFN1 PFN1 KLHDC1 KLHDC1 DYNC2H1 DYNC2H1 LOC113906743 LOC113906743 NFKBIA NFKBIA CYTH2 CYTH2 RHOG RHOG A0A4W2IDQ2 A0A4W2IDQ2 PFN3 PFN3 IRAK4 IRAK4 A0A4W2EE88 A0A4W2EE88 EXOC4 EXOC4 MAP2K3 MAP2K3 TNF TNF PTPRC PTPRC LY96 LY96 ARPC2 ARPC2 A0A4W2EHM6 A0A4W2EHM6 VPS16 VPS16 VPS18 VPS18 ARPC3 ARPC3 VPS41 VPS41 ACBD3 ACBD3 PLEKHM1 PLEKHM1 TLR5 TLR5 ARF6 ARF6 IL1B IL1B DYNLRB1 DYNLRB1 RHOB RHOB DYNC2LI1 DYNC2LI1 KLHDC2 KLHDC2 KPNA1 KPNA1 FYTTD1 FYTTD1 RIPK3 RIPK3 NCKAP1 NCKAP1 TNFSF10 TNFSF10 LOC113901903 LOC113901903 RAB17 RAB17 A0A4W2EVF1 A0A4W2EVF1 ANXA9 ANXA9 A0A4W2EVQ8 A0A4W2EVQ8 A0A4W2EVV4 A0A4W2EVV4 CXCL8 CXCL8 SMIM10L1 SMIM10L1 A0A4W2EXH4 A0A4W2EXH4 TLR6 TLR6 IL6 IL6 NME9 NME9 CYTH4 CYTH4 A0A4W2F0C7 A0A4W2F0C7 PKN1 PKN1 A0A4W2F1P2 A0A4W2F1P2 CYFIP2 CYFIP2 ANXA6 ANXA6 CYFIP1 CYFIP1 ANXA5 ANXA5 RAB5A RAB5A MAPK9 MAPK9 S100A4 S100A4 S100A16 S100A16 A0A4W2FDM7 A0A4W2FDM7 SKP1 SKP1 TCF7 TCF7 S100Z S100Z SNX33 SNX33 CHUK CHUK RAB7B RAB7B RHOA RHOA AKT1 AKT1 LOC113897645 LOC113897645 TXNDC8 TXNDC8 KPNA4 KPNA4 MAP2K2 MAP2K2 GOLGA2 GOLGA2 RAB5B RAB5B LOC113891379 LOC113891379 RELA RELA TCF7L2 TCF7L2 RILPL1 RILPL1 MAPK10 MAPK10 CCDC70 CCDC70 ANXA2 ANXA2 DYNC1LI2 DYNC1LI2 GAPDH GAPDH FHOD1 FHOD1 TRADD TRADD MYL2 MYL2 KPNA3 KPNA3 KLC3 KLC3 TAB2 TAB2 A0A4W2GK22 A0A4W2GK22 RIPK1 RIPK1 A0A4W2GYG4 A0A4W2GYG4 ARPC5 ARPC5 ACTL8 ACTL8 NLRP3 NLRP3 BAX BAX BRK1 BRK1 RRAS RRAS MYC MYC HRAS HRAS DYNLRB2 DYNLRB2 ABI3 ABI3 PFN2 PFN2 EXOC7 EXOC7 RAB9A RAB9A MAP2K7 MAP2K7 EXOC5 EXOC5 TCF7L1 TCF7L1 FBXO22 FBXO22 SNX18 SNX18 NRIP3 NRIP3 PAK1 PAK1 CASP14 CASP14 JUN JUN A0A4W2I5C3 A0A4W2I5C3 STX10 STX10 NFKB1 NFKB1 MYD88 MYD88 ARL17A ARL17A A0A4W2I9K4 A0A4W2I9K4 MAPK3 MAPK3 ARPC1B ARPC1B WASF3 WASF3 FLNB FLNB A0A4W2BNP2 A0A4W2BNP2 MYLPF MYLPF NAV2 NAV2 CTNNB1 CTNNB1 LOC113880328 LOC113880328 RAB7A RAB7A RAF1 RAF1 A0A4W2BSH8 A0A4W2BSH8 DYNLL2 DYNLL2 TRAF2 TRAF2 FYCO1 FYCO1 DYNLT3 DYNLT3 AHNAK AHNAK BCL2 BCL2 IKBKB IKBKB A0A4W2BX47 A0A4W2BX47 RFWD3 RFWD3 BAK1 BAK1 LOC113905948 LOC113905948 CASP1 CASP1 MAPK11 MAPK11 CASP7 CASP7 CENPU CENPU KLC4 KLC4 CASP3 CASP3 ARPC1A ARPC1A GSDMD GSDMD TLR2 TLR2 MAP2K4 MAP2K4 A0A4W2C3Z6 A0A4W2C3Z6 TIRAP TIRAP ARPC4 ARPC4 EXOC2 EXOC2 NRIP2 NRIP2 HSP90AA1 HSP90AA1 PIK3C2A PIK3C2A MYL12A MYL12A MYL12B MYL12B CYTH3 CYTH3 NAIP NAIP A0A4W2CBR1 A0A4W2CBR1 A0A4W2CBX4 A0A4W2CBX4 MYO6 MYO6 FADD FADD RIPK2 RIPK2 MAPK12 MAPK12 MAP3K7 MAP3K7 BIRC3 BIRC3 PIK3C2B PIK3C2B A0A4W2CHC4 A0A4W2CHC4 DDI1 DDI1 S100A10 S100A10 CASP8 CASP8 PYCARD PYCARD A0A4W2ILH9 A0A4W2ILH9 LOC113895027 LOC113895027 AKT2 AKT2 PRX PRX RPS3 RPS3 NLRC4 NLRC4 NOD1 NOD1 NPVF NPVF ATF3 ATF3 PLEKHM2 PLEKHM2 A0A4W2CP79 A0A4W2CP79 MAPK1 MAPK1 A0A4W2CR26 A0A4W2CR26 ELMO2 ELMO2 C7orf31 C7orf31 A0A4W2CRW3 A0A4W2CRW3 PIK3CD PIK3CD MYL7 MYL7 A0A4W2CWK4 A0A4W2CWK4 DYNLT1 DYNLT1 FLNC FLNC ROCK2 ROCK2 VPS39 VPS39 A0A4W2CZ95 A0A4W2CZ95 A0A4W2CZR5 A0A4W2CZR5 LOC113885433 LOC113885433 SNX9 SNX9 MYL9 MYL9 A0A4W2D1A4 A0A4W2D1A4 TLR4 TLR4 RHOC RHOC MAP2K1 MAP2K1 A0A4W2D4T7 A0A4W2D4T7 MAPK8 MAPK8 NCKAP1L NCKAP1L NAV3 NAV3 DYNC1I2 DYNC1I2 RHOJ RHOJ ARF1 ARF1 A0A4W2DBC1 A0A4W2DBC1 WASL WASL PIK3C2G PIK3C2G CD14 CD14 A0A4W2DD09 A0A4W2DD09 CDC42 CDC42 A0A4W2DG34 A0A4W2DG34 LIMCH1 LIMCH1 A0A4W2DGA1 A0A4W2DGA1 A0A4W2DGF1 A0A4W2DGF1 A0A4W2DHA5 A0A4W2DHA5 A0A4W2DHL6 A0A4W2DHL6 ANXA4 ANXA4 A0A4W2DK14 A0A4W2DK14 A0A4W2DK31 A0A4W2DK31 FOS FOS HSP90B1 HSP90B1 TUBGCP5 TUBGCP5 A0A4W2DN12 A0A4W2DN12 A0A4W2DN34 A0A4W2DN34 DNM2 DNM2 PIK3CG PIK3CG LOC113887367 LOC113887367 DYNC1LI1 DYNC1LI1 KLC2 KLC2 PIK3CA PIK3CA MLKL MLKL RILP RILP ANXA3 ANXA3 A0A4W2DSK5 A0A4W2DSK5 FHOD3 FHOD3 LOC113888945 LOC113888945 DYNC1I1 DYNC1I1 MAPK13 MAPK13 A0A4W2DVE6 A0A4W2DVE6 A0A4W2DVY2 A0A4W2DVY2 A0A4W2DWN2 A0A4W2DWN2 IL18 IL18 PIK3CB PIK3CB TNFRSF1A TNFRSF1A ACTB ACTB TXN2 TXN2 A0A4W2E090 A0A4W2E090 A0A4W2E0S0 A0A4W2E0S0 TAB1 TAB1 LEF1 LEF1 GCC2 GCC2 DYNC1H1 DYNC1H1 A0A4W2E4K6 A0A4W2E4K6 MAP2K6 MAP2K6 KLC1 KLC1 CYTH1 CYTH1 PIK3C3 PIK3C3 ACTBL2 ACTBL2 M6PR M6PR ELMO1 ELMO1 A0A4W2E7C9 A0A4W2E7C9 CSE1L CSE1L FA2H FA2H
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A4W2E9C1Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (596 aa)
RALARAS like proto-oncogene A. (206 aa)
AKT3AKT serine/threonine kinase 3. (564 aa)
RAB5CUncharacterized protein. (216 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
ABI1Abl interactor 1. (508 aa)
VPS11Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (941 aa)
PFN4Profilin; Belongs to the profilin family. (129 aa)
PFN1Profilin; Belongs to the profilin family. (140 aa)
KLHDC1Kelch domain containing 1. (422 aa)
DYNC2H1Dynein cytoplasmic 2 heavy chain 1. (4313 aa)
LOC113906743Uncharacterized protein. (1021 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
CYTH2Uncharacterized protein. (400 aa)
RHOGRas homolog family member G. (191 aa)
A0A4W2IDQ2Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
PFN3Profilin; Belongs to the profilin family. (137 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (461 aa)
A0A4W2EE88Uncharacterized protein. (509 aa)
EXOC4Exocyst complex component 4. (976 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (333 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1243 aa)
LY96Lymphocyte antigen 96. (160 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
A0A4W2EHM6Uncharacterized protein. (68 aa)
VPS16Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (839 aa)
VPS18VPS18 core subunit of CORVET and HOPS complexes. (973 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (190 aa)
VPS41Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa)
ACBD3Acyl-CoA binding domain containing 3. (528 aa)
PLEKHM1Pleckstrin homology and RUN domain containing M1. (1062 aa)
TLR5Toll like receptor 5; Belongs to the Toll-like receptor family. (858 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (148 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (266 aa)
DYNLRB1Dynein light chain roadblock-type 1. (165 aa)
RHOBRas homolog family member B. (181 aa)
DYNC2LI1Dynein cytoplasmic 2 light intermediate chain 1. (352 aa)
KLHDC2Kelch domain containing 2. (406 aa)
KPNA1Karyopherin subunit alpha 1. (954 aa)
FYTTD1Forty-two-three domain containing 1. (318 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (504 aa)
NCKAP1NCK associated protein 1. (1139 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (287 aa)
LOC113901903Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
RAB17RAB17, member RAS oncogene family. (233 aa)
A0A4W2EVF1Uncharacterized protein. (308 aa)
ANXA9Annexin. (345 aa)
A0A4W2EVQ8Uncharacterized protein; Belongs to the profilin family. (69 aa)
A0A4W2EVV4Profilin; Belongs to the profilin family. (87 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
SMIM10L1Small integral membrane protein 10 like 1. (68 aa)
A0A4W2EXH4EF-hand domain-containing protein. (1414 aa)
TLR6Toll-like receptor. (796 aa)
IL6Interleukin 6. (208 aa)
NME9NME/NM23 family member 9; Belongs to the NDK family. (332 aa)
CYTH4Cytohesin 4. (394 aa)
A0A4W2F0C7Uncharacterized protein. (114 aa)
PKN1Protein kinase N1. (956 aa)
A0A4W2F1P2ANAPC4_WD40 domain-containing protein. (204 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
ANXA6Annexin. (751 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
ANXA5Annexin. (375 aa)
RAB5AUncharacterized protein. (215 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
S100A4EF-hand domain-containing protein. (203 aa)
S100A16Protein S100; Belongs to the S-100 family. (103 aa)
A0A4W2FDM7TIR domain-containing protein. (1029 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
TCF7Transcription factor 7. (473 aa)
S100ZProtein S100; Belongs to the S-100 family. (99 aa)
SNX33Sorting nexin. (571 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (774 aa)
RAB7BRAB7B, member RAS oncogene family. (200 aa)
RHOARas homolog family member A. (193 aa)
AKT1Non-specific serine/threonine protein kinase. (747 aa)
LOC113897645Thioredoxin; Belongs to the thioredoxin family. (105 aa)
TXNDC8Thioredoxin domain containing 8. (127 aa)
KPNA4Importin subunit alpha; Functions in nuclear protein import. (511 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (447 aa)
GOLGA2Uncharacterized protein. (1032 aa)
RAB5BRAB5B, member RAS oncogene family. (215 aa)
LOC113891379Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
TCF7L2Transcription factor 7 like 2. (652 aa)
RILPL1Rab interacting lysosomal protein like 1. (411 aa)
MAPK10Mitogen-activated protein kinase. (425 aa)
CCDC70Coiled-coil domain containing 70. (233 aa)
ANXA2Annexin. (394 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (628 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
FHOD1Formin homology 2 domain containing 1. (1228 aa)
TRADDTNFRSF1A associated via death domain. (312 aa)
MYL2Myosin light chain 2. (166 aa)
KPNA3Importin subunit alpha; Functions in nuclear protein import. (521 aa)
KLC3Kinesin light chain 3. (578 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
A0A4W2GK22Dynein light chain. (84 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (669 aa)
A0A4W2GYG4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (379 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
ACTL8Actin like 8; Belongs to the actin family. (365 aa)
NLRP3NLR family pyrin domain containing 3. (1031 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)
RRASRAS related. (218 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
DYNLRB2Dynein light chain roadblock-type 2. (126 aa)
ABI3ABI family member 3. (359 aa)
PFN2Profilin; Belongs to the profilin family. (142 aa)
EXOC7Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (707 aa)
RAB9ARAB9A, member RAS oncogene family. (203 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (658 aa)
EXOC5Exocyst complex component 5. (708 aa)
TCF7L1Transcription factor 7 like 1. (588 aa)
FBXO22F-box protein 22. (404 aa)
SNX18Sorting nexin. (626 aa)
NRIP3Nuclear receptor interacting protein 3. (251 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
CASP14Caspase 14; Belongs to the peptidase C14A family. (242 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (335 aa)
A0A4W2I5C3Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (70 aa)
STX10Syntaxin 10. (249 aa)
NFKB1Nuclear factor kappa B subunit 1. (974 aa)
MYD88MYD88 innate immune signal transduction adaptor. (384 aa)
ARL17AUncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (181 aa)
A0A4W2I9K4Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (58 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (456 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (372 aa)
WASF3WASP family member 3. (501 aa)
FLNBFilamin B. (2771 aa)
A0A4W2BNP2Uncharacterized protein; Belongs to the peptidase C14A family. (476 aa)
MYLPFMyosin light chain, phosphorylatable, fast skeletal muscle. (170 aa)
NAV2Neuron navigator 2. (2451 aa)
CTNNB1Catenin beta 1. (774 aa)
LOC113880328Uncharacterized protein; Belongs to the peptidase C14A family. (368 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
A0A4W2BSH8Thioredoxin domain-containing protein. (545 aa)
DYNLL2Dynein light chain. (128 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (516 aa)
FYCO1FYVE and coiled-coil domain containing 1. (1454 aa)
DYNLT3Dynein light chain Tctex-type 3. (105 aa)
AHNAKAHNAK nucleoprotein. (5896 aa)
BCL2BCL2 apoptosis regulator. (229 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
A0A4W2BX47Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (79 aa)
RFWD3Ring finger and WD repeat domain 3. (790 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
LOC113905948Uncharacterized protein; Belongs to the peptidase C14A family. (446 aa)
CASP1Uncharacterized protein; Belongs to the peptidase C14A family. (416 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (320 aa)
CENPUCentromere protein U. (433 aa)
KLC4Kinesin light chain 4. (616 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
ARPC1AWD_REPEATS_REGION domain-containing protein. (430 aa)
GSDMDGasdermin D. (543 aa)
TLR2Toll like receptor 2; Belongs to the Toll-like receptor family. (861 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (412 aa)
A0A4W2C3Z6Uncharacterized protein. (757 aa)
TIRAPTIR domain containing adaptor protein. (327 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
EXOC2Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (923 aa)
NRIP2Nuclear receptor interacting protein 2. (288 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (774 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1831 aa)
MYL12AMyosin light chain 12A. (178 aa)
MYL12BMyosin light chain 12B. (171 aa)
CYTH3Cytohesin 3. (418 aa)
NAIPNLR family apoptosis inhibitory protein. (1406 aa)
A0A4W2CBR1Dynein light chain. (63 aa)
A0A4W2CBX4Uncharacterized protein. (152 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1289 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (209 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (539 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1634 aa)
A0A4W2CHC4Uncharacterized protein. (110 aa)
DDI1DNA damage inducible 1 homolog 1. (396 aa)
S100A10S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (485 aa)
PYCARDPYD and CARD domain containing. (195 aa)
A0A4W2ILH9Uncharacterized protein. (72 aa)
LOC113895027Dynein light chain. (89 aa)
AKT2AKT serine/threonine kinase 2. (603 aa)
PRXPeriaxin. (1483 aa)
RPS3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (281 aa)
NLRC4NLR family CARD domain containing 4. (1017 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (954 aa)
NPVFNeuropeptide VF precursor. (210 aa)
ATF3Activating transcription factor 3. (253 aa)
PLEKHM2Pleckstrin homology and RUN domain containing M2. (1025 aa)
A0A4W2CP79Annexin. (335 aa)
MAPK1Mitogen-activated protein kinase. (634 aa)
A0A4W2CR26TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa)
ELMO2Engulfment and cell motility 2. (756 aa)
C7orf31Chromosome 7 open reading frame 31. (584 aa)
A0A4W2CRW3Annexin. (346 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
MYL7Myosin light chain 7. (226 aa)
A0A4W2CWK4Skp1_POZ domain-containing protein. (65 aa)
DYNLT1Dynein light chain Tctex-type 1. (109 aa)
FLNCFilamin C. (2736 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1469 aa)
VPS39VPS39 subunit of HOPS complex. (875 aa)
A0A4W2CZ95Uncharacterized protein. (506 aa)
A0A4W2CZR5Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (406 aa)
LOC113885433Annexin. (327 aa)
SNX9Sorting nexin. (624 aa)
MYL9Myosin light chain 9. (172 aa)
A0A4W2D1A4Dynein light chain. (89 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (841 aa)
RHOCRas homolog family member C. (193 aa)
MAP2K1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa)
A0A4W2D4T7Uncharacterized protein. (356 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
NCKAP1LNCK associated protein 1 like. (1134 aa)
NAV3Neuron navigator 3. (2385 aa)
DYNC1I2Dynein cytoplasmic 1 intermediate chain 2. (638 aa)
RHOJRas homolog family member J. (236 aa)
ARF1ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
A0A4W2DBC1Dynein light chain. (87 aa)
WASLWASP like actin nucleation promoting factor. (511 aa)
PIK3C2GPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family. (1487 aa)
CD14Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (373 aa)
A0A4W2DD09Protein S100; Belongs to the S-100 family. (105 aa)
CDC42Cell division cycle 42. (191 aa)
A0A4W2DG34Dynein light chain. (69 aa)
LIMCH1LIM and calponin homology domains 1. (1570 aa)
A0A4W2DGA1Protein S100; Belongs to the S-100 family. (142 aa)
A0A4W2DGF1Uncharacterized protein. (258 aa)
A0A4W2DHA5Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (159 aa)
A0A4W2DHL6Uncharacterized protein. (165 aa)
ANXA4Annexin. (321 aa)
A0A4W2DK14Uncharacterized protein. (350 aa)
A0A4W2DK31Reverse transcriptase domain-containing protein. (340 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
HSP90B1Heat shock protein 90 beta family member 1. (808 aa)
TUBGCP5Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (1024 aa)
A0A4W2DN12Uncharacterized protein. (79 aa)
A0A4W2DN34KH type-2 domain-containing protein. (85 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (880 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1171 aa)
LOC113887367Uncharacterized protein. (78 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (524 aa)
KLC2Kinesin light chain 2. (624 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
MLKLMixed lineage kinase domain like pseudokinase. (495 aa)
RILPRab interacting lysosomal protein. (369 aa)
ANXA3Annexin. (323 aa)
A0A4W2DSK5TNFR-Cys domain-containing protein. (251 aa)
FHOD3Formin homology 2 domain containing 3. (1612 aa)
LOC113888945Uncharacterized protein. (623 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (645 aa)
MAPK13Mitogen-activated protein kinase. (455 aa)
A0A4W2DVE6Uncharacterized protein. (870 aa)
A0A4W2DVY2S_100 domain-containing protein. (1358 aa)
A0A4W2DWN2Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (181 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
TNFRSF1ATNF receptor superfamily member 1A. (471 aa)
ACTBActin beta. (375 aa)
TXN2Thioredoxin domain-containing protein. (221 aa)
A0A4W2E090Reverse transcriptase domain-containing protein. (376 aa)
A0A4W2E0S0Dynein light chain. (89 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (505 aa)
LEF1Lymphoid enhancer binding factor 1. (430 aa)
GCC2GRIP and coiled-coil domain containing 2. (1824 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4645 aa)
A0A4W2E4K6Gp_dh_C domain-containing protein. (126 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
KLC1Uncharacterized protein. (657 aa)
CYTH1Cytohesin 1. (455 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
ACTBL2Actin beta like 2. (376 aa)
M6PRMannose-6-phosphate receptor, cation dependent. (279 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
A0A4W2E7C9TNF receptor-associated factor. (411 aa)
CSE1LChromosome segregation 1 like. (973 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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