STRINGSTRING
PTGER2 PTGER2 GNG10 GNG10 ADCY4 ADCY4 ATF2 ATF2 GNGT1 GNGT1 A0A4W2DBM4 A0A4W2DBM4 A0A4W2DC91 A0A4W2DC91 ITPR2 ITPR2 A0A4W2DGC7 A0A4W2DGC7 ARHGEF11 ARHGEF11 PTGER3 PTGER3 A0A4W2DHH5 A0A4W2DHH5 IL6R IL6R A0A4W2DJH4 A0A4W2DJH4 CREB3L3 CREB3L3 A0A4W2DLH5 A0A4W2DLH5 GNAI1 GNAI1 NFATC4 NFATC4 CCL5 CCL5 NRAS NRAS CCR5 CCR5 PIK3CA PIK3CA ERAS ERAS CRK CRK TSC1 TSC1 CCL2 CCL2 PPP3CC PPP3CC MAPK13 MAPK13 A0A4W2DUV7 A0A4W2DUV7 A0A4W2DVS8 A0A4W2DVS8 A0A4W2DW81 A0A4W2DW81 LOC113882059 LOC113882059 ROCK1 ROCK1 CREB3L4 CREB3L4 A0A4W2DX15 A0A4W2DX15 KRAS KRAS A0A4W2DXS4 A0A4W2DXS4 PIK3CB PIK3CB TNFRSF1A TNFRSF1A A0A4W2DYV7 A0A4W2DYV7 ADCY7 ADCY7 VEGFA VEGFA ATF6B ATF6B ADCY8 ADCY8 A0A4W2E497 A0A4W2E497 GNB3 GNB3 MAP2K6 MAP2K6 GNG8 GNG8 CGAS CGAS CX3CL1 CX3CL1 CREB1 CREB1 GNB1 GNB1 A0A4W2E842 A0A4W2E842 PLCB4 PLCB4 CREB3 CREB3 CCR1 CCR1 ARHGEF12 ARHGEF12 STAT3 STAT3 ADCY1 ADCY1 FASLG FASLG EIF4EBP1 EIF4EBP1 CCND1 CCND1 AKT3 AKT3 PRKCG PRKCG SOS2 SOS2 TAPBP TAPBP CDKN1A CDKN1A IL1R1 IL1R1 TNF TNF A0A4W2EHH7 A0A4W2EHH7 A0A4W2EHI1 A0A4W2EHI1 PDIA3 PDIA3 A0A4W2EIV4 A0A4W2EIV4 IL1B IL1B CDK4 CDK4 CREB3L2 CREB3L2 ADCY3 ADCY3 LOC113897812 LOC113897812 A0A4W2EML2 A0A4W2EML2 A0A4W2EML3 A0A4W2EML3 A0A4W2EMM2 A0A4W2EMM2 ADCY5 ADCY5 LOC113899279 LOC113899279 SP1 SP1 CXCL12 CXCL12 GNAI3 GNAI3 CALML4 CALML4 RHEB RHEB GNB4 GNB4 PTK2B PTK2B LOC113901903 LOC113901903 CXCL8 CXCL8 PIK3R3 PIK3R3 IL6 IL6 IL10RB IL10RB TMEM173 TMEM173 RAC2 RAC2 PTGER1 PTGER1 CXCR4 CXCR4 PPP3CA PPP3CA A0A4W2F2N7 A0A4W2F2N7 ITGAV ITGAV PDGFRA PDGFRA GNAI2 GNAI2 CHUK CHUK GNAQ GNAQ RHOA RHOA SRC SRC AKT1 AKT1 CDK6 CDK6 GNG11 GNG11 PIK3R2 PIK3R2 MAP2K2 MAP2K2 CREB5 CREB5 GNG7 GNG7 GNA11 GNA11 LOC113891379 LOC113891379 RELA RELA A0A4W2G5Q0 A0A4W2G5Q0 PRKACA PRKACA PRKCA PRKCA TRADD TRADD GNA13 GNA13 LOC113878185 LOC113878185 JAK1 JAK1 NFATC3 NFATC3 LOC113897811 LOC113897811 IL10RA IL10RA LOC113897795 LOC113897795 RIPK1 RIPK1 PTGS2 PTGS2 A0A4W2GYG4 A0A4W2GYG4 PRKACB PRKACB BAX BAX GNG5 GNG5 E2F1 E2F1 MYC MYC E2F2 E2F2 HRAS HRAS RB1 RB1 TP53 TP53 PRKCB PRKCB LOC113878239 LOC113878239 NFKB1 NFKB1 CCR3 CCR3 MAPK3 MAPK3 SOS1 SOS1 LOC113896989 LOC113896989 A0A4W2IDQ2 A0A4W2IDQ2 NFKBIA NFKBIA CASP8 CASP8 LOC113888607 LOC113888607 A0A4W2BK72 A0A4W2BK72 TSC2 TSC2 GNG13 GNG13 E2F3 E2F3 ITPR1 ITPR1 ADCY9 ADCY9 GNB2 GNB2 CTNNB1 CTNNB1 A0A4W2BQS2 A0A4W2BQS2 A0A4W2BQT6 A0A4W2BQT6 GNG3 GNG3 PLCB3 PLCB3 RPS6KB1 RPS6KB1 RAF1 RAF1 TRAF2 TRAF2 BCAR1 BCAR1 RPS6KB2 RPS6KB2 PPP3CB PPP3CB IKBKB IKBKB LOC113881324 LOC113881324 BAK1 BAK1 ITPR3 ITPR3 ELK1 ELK1 GNG4 GNG4 MAPK11 MAPK11 ATF4 ATF4 TAP1 TAP1 CASP3 CASP3 A0A4W2C1N1 A0A4W2C1N1 LOC113881805 LOC113881805 LOC113882062 LOC113882062 A0A4W2C2X4 A0A4W2C2X4 FAS FAS TRAF5 TRAF5 A0A4W2C595 A0A4W2C595 A0A4W2C618 A0A4W2C618 A0A4W2C624 A0A4W2C624 PXN PXN RAC3 RAC3 PIK3R1 PIK3R1 GNAO1 GNAO1 GNA12 GNA12 RAC1 RAC1 EGFR EGFR FADD FADD PTGER4 PTGER4 PLCB1 PLCB1 A0A4W2CEF6 A0A4W2CEF6 MAPK12 MAPK12 A0A4W2CFU1 A0A4W2CFU1 AKT2 AKT2 LPXN LPXN ARHGEF1 ARHGEF1 A0A4W2CK57 A0A4W2CK57 GRB2 GRB2 BID BID CREB3L1 CREB3L1 PTK2 PTK2 RUFY4 RUFY4 CXCR2 CXCR2 IRF3 IRF3 NFATC2 NFATC2 MAPK1 MAPK1 CRKL CRKL AKAP13 AKAP13 C7orf31 C7orf31 PIK3CD PIK3CD MDM2 MDM2 GNG2 GNG2 MTOR MTOR GNB5 GNB5 TBK1 TBK1 PLCB2 PLCB2 A0A4W2CWS2 A0A4W2CWS2 A0A4W2CWV7 A0A4W2CWV7 GNAS GNAS A0A4W2CX00 A0A4W2CX00 GSK3B GSK3B ADCY2 ADCY2 ROCK2 ROCK2 PTRHD1 PTRHD1 ADCY6 ADCY6 A0A4W2D155 A0A4W2D155 RHEBL1 RHEBL1 CALM1 CALM1 CASP9 CASP9 CSDE1 CSDE1 MAP2K1 MAP2K1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTGER2Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (352 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ATF2Activating transcription factor 2. (447 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (134 aa)
A0A4W2DBM4Ig-like domain-containing protein; Belongs to the MHC class I family. (475 aa)
A0A4W2DC91Uncharacterized protein. (241 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
A0A4W2DGC7Uncharacterized protein. (186 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1590 aa)
PTGER3Prostaglandin E receptor 3. (389 aa)
A0A4W2DHH5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
IL6RInterleukin 6 receptor. (464 aa)
A0A4W2DJH4Uncharacterized protein. (189 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (456 aa)
A0A4W2DLH5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (103 aa)
GNAI1G protein subunit alpha i1. (417 aa)
NFATC4Nuclear factor of activated T cells 4. (979 aa)
CCL5C-C motif chemokine. (91 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
CCR5C-C motif chemokine receptor 5 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family. (352 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ERASES cell expressed Ras. (185 aa)
CRKCRK proto-oncogene, adaptor protein. (376 aa)
TSC1TSC complex subunit 1. (1165 aa)
CCL2C-C motif chemokine. (99 aa)
PPP3CCSerine/threonine-protein phosphatase. (531 aa)
MAPK13Mitogen-activated protein kinase. (455 aa)
A0A4W2DUV7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (87 aa)
A0A4W2DVS8Ig-like domain-containing protein. (529 aa)
A0A4W2DW81Ig-like domain-containing protein; Belongs to the MHC class I family. (343 aa)
LOC113882059Ig-like domain-containing protein; Belongs to the MHC class I family. (366 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1356 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (393 aa)
A0A4W2DX15Ig-like domain-containing protein. (199 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
A0A4W2DXS4RING-type domain-containing protein. (131 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
TNFRSF1ATNF receptor superfamily member 1A. (471 aa)
A0A4W2DYV7Uncharacterized protein. (202 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1096 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (394 aa)
ATF6BActivating transcription factor 6 beta. (718 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1253 aa)
A0A4W2E497MHC_I-like_Ag-recog domain-containing protein; Belongs to the MHC class I family. (243 aa)
GNB3G protein subunit beta 3. (356 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
CGASCyclic GMP-AMP synthase. (513 aa)
CX3CL1SCY domain-containing protein. (458 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
GNB1G protein subunit beta 1. (358 aa)
A0A4W2E842C-C motif chemokine. (93 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1218 aa)
CREB3cAMP responsive element binding protein 3. (365 aa)
CCR1C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1544 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1197 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (277 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (178 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (428 aa)
AKT3AKT serine/threonine kinase 3. (564 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (771 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
TAPBPTAP binding protein. (494 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (161 aa)
IL1R1Interleukin 1 receptor type 1. (573 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (333 aa)
A0A4W2EHH7Uncharacterized protein. (91 aa)
A0A4W2EHI1Uncharacterized protein. (170 aa)
PDIA3Protein disulfide-isomerase. (505 aa)
A0A4W2EIV4EF-hand domain-containing protein; Belongs to the calmodulin family. (87 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (266 aa)
CDK4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (303 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (568 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
LOC113897812Uncharacterized protein. (186 aa)
A0A4W2EML2Uncharacterized protein. (186 aa)
A0A4W2EML3Uncharacterized protein. (189 aa)
A0A4W2EMM2Uncharacterized protein. (187 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1259 aa)
LOC113899279Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (118 aa)
SP1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1209 aa)
CXCL12SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family. (204 aa)
GNAI3G protein subunit alpha i3. (354 aa)
CALML4Calmodulin like 4. (153 aa)
RHEBUncharacterized protein. (214 aa)
GNB4G protein subunit beta 4. (340 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1008 aa)
LOC113901903Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
PIK3R3Uncharacterized protein. (461 aa)
IL6Interleukin 6. (208 aa)
IL10RBInterleukin 10 receptor subunit beta. (387 aa)
TMEM173Transmembrane protein 173. (484 aa)
RAC2Rac family small GTPase 2. (209 aa)
PTGER1Prostaglandin E receptor 1. (441 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (353 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
A0A4W2F2N7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (198 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1098 aa)
GNAI2G protein subunit alpha i2. (436 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (774 aa)
GNAQG protein subunit alpha q. (359 aa)
RHOARas homolog family member A. (193 aa)
SRCTyrosine-protein kinase. (559 aa)
AKT1Non-specific serine/threonine protein kinase. (747 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
PIK3R2Uncharacterized protein. (724 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (447 aa)
CREB5cAMP responsive element binding protein 5. (538 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNA11G protein subunit alpha 11. (359 aa)
LOC113891379Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
A0A4W2G5Q0Protein kinase domain-containing protein. (79 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
TRADDTNFRSF1A associated via death domain. (312 aa)
GNA13G protein subunit alpha 13. (377 aa)
LOC113878185C-C motif chemokine. (92 aa)
JAK1Tyrosine-protein kinase. (1110 aa)
NFATC3Nuclear factor of activated T cells 3. (1073 aa)
LOC113897811Uncharacterized protein. (186 aa)
IL10RAInterleukin 10 receptor subunit alpha. (580 aa)
LOC113897795Uncharacterized protein. (189 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (669 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
A0A4W2GYG4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (379 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (367 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
E2F1E2F transcription factor 1. (437 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
E2F2E2F transcription factor 2. (437 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
RB1RB transcriptional corepressor 1. (928 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (499 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
LOC113878239C-C motif chemokine. (89 aa)
NFKB1Nuclear factor kappa B subunit 1. (974 aa)
CCR3C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (358 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (456 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1598 aa)
LOC113896989Uncharacterized protein. (186 aa)
A0A4W2IDQ2Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (485 aa)
LOC113888607Uncharacterized protein. (189 aa)
A0A4W2BK72Uncharacterized protein. (172 aa)
TSC2TSC complex subunit 2. (1887 aa)
GNG13G protein subunit gamma 13. (67 aa)
E2F3E2F transcription factor 3. (465 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2757 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1117 aa)
GNB2G protein subunit beta 2. (340 aa)
CTNNB1Catenin beta 1. (774 aa)
A0A4W2BQS2C-C motif chemokine. (87 aa)
A0A4W2BQT6SCY domain-containing protein. (170 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (516 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (919 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (485 aa)
PPP3CBSerine/threonine-protein phosphatase. (524 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
LOC113881324Uncharacterized protein. (719 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2664 aa)
ELK1ETS transcription factor ELK1. (432 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
ATF4Activating transcription factor 4. (348 aa)
TAP1Transporter 1, ATP binding cassette subfamily B member. (838 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
A0A4W2C1N1MHC_I-like_Ag-recog domain-containing protein. (218 aa)
LOC113881805Ig-like domain-containing protein; Belongs to the MHC class I family. (374 aa)
LOC113882062Ig-like domain-containing protein; Belongs to the MHC class I family. (365 aa)
A0A4W2C2X4Ig-like domain-containing protein; Belongs to the MHC class I family. (356 aa)
FASFas cell surface death receptor. (323 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
A0A4W2C595Ig-like domain-containing protein; Belongs to the MHC class I family. (325 aa)
A0A4W2C618Ig-like domain-containing protein; Belongs to the MHC class I family. (353 aa)
A0A4W2C624Ig-like domain-containing protein; Belongs to the MHC class I family. (327 aa)
PXNUncharacterized protein. (1066 aa)
RAC3Rac family small GTPase 3. (258 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
GNAO1G protein subunit alpha o1. (377 aa)
GNA12G protein subunit alpha 12. (382 aa)
RAC1Rac family small GTPase 1. (257 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (209 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (492 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
A0A4W2CEF6Integrin beta; Belongs to the integrin beta chain family. (784 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
A0A4W2CFU1Protein kinase domain-containing protein. (79 aa)
AKT2AKT serine/threonine kinase 2. (603 aa)
LPXNLeupaxin. (399 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (968 aa)
A0A4W2CK57Ig-like domain-containing protein; Belongs to the MHC class I family. (375 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (193 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (560 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1139 aa)
RUFY4RUN and FYVE domain containing 4. (571 aa)
CXCR2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (363 aa)
IRF3Interferon regulatory factor 3. (417 aa)
NFATC2Nuclear factor of activated T cells 2. (914 aa)
MAPK1Mitogen-activated protein kinase. (634 aa)
CRKLCRK like proto-oncogene, adaptor protein. (302 aa)
AKAP13A-kinase anchoring protein 13. (2887 aa)
C7orf31Chromosome 7 open reading frame 31. (584 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
MDM2MDM2 proto-oncogene. (689 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (123 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
GNB5G protein subunit beta 5. (452 aa)
TBK1TANK binding kinase 1. (729 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1226 aa)
A0A4W2CWS2Uncharacterized protein. (154 aa)
A0A4W2CWV7Uncharacterized protein. (189 aa)
GNASGNAS complex locus. (1004 aa)
A0A4W2CX00Uncharacterized protein. (189 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (432 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1096 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1469 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
A0A4W2D155Uncharacterized protein. (153 aa)
RHEBL1RHEB like 1. (195 aa)
CALM1Uncharacterized protein; Belongs to the calmodulin family. (365 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (452 aa)
CSDE1Cold shock domain containing E1. (844 aa)
MAP2K1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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