STRINGSTRING
A0A4W2D781 A0A4W2D781 NFKBIA NFKBIA MAPK3 MAPK3 A0A4W2I9W6 A0A4W2I9W6 A0A4W2I9H2 A0A4W2I9H2 NFKB1 NFKB1 JUN JUN TP53 TP53 RB1 RB1 LOC113881562 LOC113881562 TLNRD1 TLNRD1 A0A4W2HUR1 A0A4W2HUR1 MMP7 MMP7 CDK2 CDK2 CDKN2C CDKN2C SLC25A6 SLC25A6 LCK LCK TRRAP TRRAP VDAC1 VDAC1 XPO1 XPO1 TBPL2 TBPL2 CDC20 CDC20 TGFB2 TGFB2 HRAS HRAS TBPL1 TBPL1 E2F2 E2F2 MYC MYC E2F1 E2F1 A0A4W2H7Y7 A0A4W2H7Y7 CCNA2 CCNA2 ETS1 ETS1 BAX BAX PRKACB PRKACB A0A4W2GYG4 A0A4W2GYG4 BCL2L1 BCL2L1 CDKN2B CDKN2B NFATC3 NFATC3 LOC113899187 LOC113899187 JAK1 JAK1 CCND2 CCND2 PTEN PTEN NFYB NFYB A0A4W2GF22 A0A4W2GF22 PRKACA PRKACA CRTC3 CRTC3 MAPK10 MAPK10 A0A4W2G5Q0 A0A4W2G5Q0 RELA RELA ANAPC4 ANAPC4 HLA-DOA HLA-DOA CREB5 CREB5 MSX1 MSX1 MAP2K2 MAP2K2 VDAC2 VDAC2 PIK3R2 PIK3R2 AKT1 AKT1 ELK4 ELK4 IL2 IL2 CHUK CHUK IL15 IL15 TNFRSF13C TNFRSF13C MAPK9 MAPK9 KAT2B KAT2B ITGB2 ITGB2 PPP3CA PPP3CA A0A4W2F1Y8 A0A4W2F1Y8 A0A4W2F1C1 A0A4W2F1C1 IL6 IL6 JAK3 JAK3 PIK3R3 PIK3R3 SLC2A1 SLC2A1 SMAD3 SMAD3 A0A4W2ES87 A0A4W2ES87 A0A4W2ES53 A0A4W2ES53 A0A4W2ES23 A0A4W2ES23 A0A4W2ERP9 A0A4W2ERP9 A0A4W2ERN6 A0A4W2ERN6 CSF2 CSF2 A0A4W2ERJ9 A0A4W2ERJ9 A0A4W2ERJ1 A0A4W2ERJ1 A0A4W2ERG5 A0A4W2ERG5 A0A4W2ERF0 A0A4W2ERF0 TGFB3 TGFB3 A0A4W2EQH2 A0A4W2EQH2 A0A4W2EQG3 A0A4W2EQG3 A0A4W2EQB9 A0A4W2EQB9 A0A4W2EQA0 A0A4W2EQA0 A0A4W2EQ96 A0A4W2EQ96 A0A4W2EQ07 A0A4W2EQ07 A0A4W2EPY6 A0A4W2EPY6 TBP TBP A0A4W2EP15 A0A4W2EP15 LOC113899279 LOC113899279 ADCY5 ADCY5 ADCY3 ADCY3 CREB3L2 CREB3L2 BUB1B BUB1B CDK4 CDK4 CCNE2 CCNE2 RANBP1 RANBP1 SPI1 SPI1 RELB RELB A0A4W2EJS6 A0A4W2EJS6 CCNB2 CCNB2 TNF TNF CCND3 CCND3 A0A4W2EEW1 A0A4W2EEW1 IL1R2 IL1R2 IL1R1 IL1R1 CDKN1A CDKN1A A0A4W2EDY1 A0A4W2EDY1 STAT5A STAT5A RANBP3L RANBP3L AKT3 AKT3 CCNE1 CCNE1 A0A4W2EBF5 A0A4W2EBF5 CCND1 CCND1 IL2RA IL2RA ADCY1 ADCY1 CD40 CD40 CREB3 CREB3 TGFBR2 TGFBR2 A0A4W2E8M1 A0A4W2E8M1 SPIB SPIB CDC20B CDC20B CREB1 CREB1 MAP3K3 MAP3K3 CHEK2 CHEK2 A0A4W2E497 A0A4W2E497 NRP1 NRP1 ADCY8 ADCY8 KAT2A KAT2A MAP3K14 MAP3K14 ATF6B ATF6B LOC113881774 LOC113881774 MSX2 MSX2 IL2RG IL2RG ADCY7 ADCY7 TNFRSF1A TNFRSF1A MAD1L1 MAD1L1 PIK3CB PIK3CB KRAS KRAS A0A4W2DXK0 A0A4W2DXK0 A0A4W2DX15 A0A4W2DX15 CREB3L4 CREB3L4 CDC23 CDC23 LOC113882059 LOC113882059 A0A4W2DW81 A0A4W2DW81 A0A4W2DVS8 A0A4W2DVS8 BUB3 BUB3 PPP3CC PPP3CC HLA-DMA HLA-DMA EGR2 EGR2 ATM ATM A0A4W2DS38 A0A4W2DS38 A0A4W2DRK4 A0A4W2DRK4 CHEK1 CHEK1 ERAS ERAS SMAD4 SMAD4 PIK3CA PIK3CA ANAPC2 ANAPC2 A0A4W2DPN4 A0A4W2DPN4 NRAS NRAS A0A4W2DP28 A0A4W2DP28 A0A4W2DNG0 A0A4W2DNG0 A0A4W2DNF6 A0A4W2DNF6 A0A4W2DMM0 A0A4W2DMM0 TRBV24-1 TRBV24-1 NFATC4 NFATC4 ITGAL ITGAL A0A4W2DMB6 A0A4W2DMB6 FOS FOS CREB3L3 CREB3L3 A0A4W2DK85 A0A4W2DK85 A0A4W2DK77 A0A4W2DK77 IL2RB IL2RB CREBBP CREBBP MAD2L1 MAD2L1 FDPS FDPS ETS2 ETS2 ATR ATR EGR1 EGR1 CRTC2 CRTC2 PTTG1 PTTG1 CDKN2A CDKN2A TCF3 TCF3 A0A4W2DCT4 A0A4W2DCT4 A0A4W2DBM4 A0A4W2DBM4 TLN2 TLN2 CRTC1 CRTC1 LOC113896623 LOC113896623 CANX CANX TLN1 TLN1 A0A4W2D801 A0A4W2D801 ATF2 ATF2 A0A4W2D7C1 A0A4W2D7C1 A0A4W2D760 A0A4W2D760 A0A4W2D724 A0A4W2D724 ADCY4 ADCY4 A0A4W2D709 A0A4W2D709 A0A4W2D704 A0A4W2D704 A0A4W2D608 A0A4W2D608 A0A4W2D5P0 A0A4W2D5P0 A0A4W2D5H8 A0A4W2D5H8 A0A4W2D5G0 A0A4W2D5G0 A0A4W2D5F7 A0A4W2D5F7 A0A4W2D597 A0A4W2D597 A0A4W2D552 A0A4W2D552 A0A4W2D547 A0A4W2D547 CDC26 CDC26 A0A4W2D520 A0A4W2D520 MAPK8 MAPK8 MAP2K1 MAP2K1 CSDE1 CSDE1 ESPL1 ESPL1 A0A4W2D326 A0A4W2D326 A0A4W2D2W9 A0A4W2D2W9 A0A4W2D2T1 A0A4W2D2T1 A0A4W2D2S8 A0A4W2D2S8 A0A4W2D2S0 A0A4W2D2S0 A0A4W2D2R2 A0A4W2D2R2 A0A4W2D2L8 A0A4W2D2L8 ANAPC1 ANAPC1 DLG1 DLG1 ADCY6 ADCY6 A0A4W2D0I4 A0A4W2D0I4 A0A4W2D0G3 A0A4W2D0G3 PTRHD1 PTRHD1 A0A4W2D0E0 A0A4W2D0E0 A0A4W2D0D6 A0A4W2D0D6 A0A4W2D095 A0A4W2D095 A0A4W2D056 A0A4W2D056 ADCY2 ADCY2 A0A4W2CY87 A0A4W2CY87 CDC16 CDC16 ANAPC7 ANAPC7 PIK3CD PIK3CD MAPK1 MAPK1 CD4 CD4 NFATC2 NFATC2 LTBR LTBR TGFBR1 TGFBR1 CREB3L1 CREB3L1 A0A4W2CK57 A0A4W2CK57 SRF SRF TGFB1 TGFB1 AKT2 AKT2 A0A4W2CHX7 A0A4W2CHX7 A0A4W2CFU3 A0A4W2CFU3 A0A4W2CFU1 A0A4W2CFU1 TERT TERT ZFP36 ZFP36 RAN RAN STAT5B STAT5B CDC27 CDC27 MAP3K1 MAP3K1 A0A4W2CCQ9 A0A4W2CCQ9 FOSL1 FOSL1 ANAPC11 ANAPC11 ANAPC5 ANAPC5 PIK3R1 PIK3R1 GPS2 GPS2 A0A4W2C624 A0A4W2C624 A0A4W2C618 A0A4W2C618 A0A4W2C595 A0A4W2C595 A0A4W2C3Y8 A0A4W2C3Y8 MAP2K4 MAP2K4 A0A4W2C2X4 A0A4W2C2X4 NFKB2 NFKB2 LOC113882062 LOC113882062 LOC113881805 LOC113881805 A0A4W2C1X2 A0A4W2C1X2 A0A4W2C1N1 A0A4W2C1N1 PTK7 PTK7 LTA LTA ANAPC10 ANAPC10 A0A4W2C1F6 A0A4W2C1F6 HLA-DOB HLA-DOB ATF4 ATF4 EP300 EP300 HLA-DRA HLA-DRA ELK1 ELK1 HLA-DQB1 HLA-DQB1 SLC25A4 SLC25A4 A0A4W2BXT5 A0A4W2BXT5 CD3D CD3D SLC25A31 SLC25A31 IKBKB IKBKB A0A4W2BVZ1 A0A4W2BVZ1 PPP3CB PPP3CB CD3E CD3E VDAC3 VDAC3 A0A4W2BUF7 A0A4W2BUF7 VAC14 VAC14 SMAD2 SMAD2 KAT5 KAT5 A0A4W2BS58 A0A4W2BS58 ADCY9 ADCY9 CCNA1 CCNA1 E2F3 E2F3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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A0A4W2D781Ig-like domain-containing protein. (137 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (456 aa)
A0A4W2I9W6Ig-like domain-containing protein. (167 aa)
A0A4W2I9H2Ig-like domain-containing protein. (102 aa)
NFKB1Nuclear factor kappa B subunit 1. (974 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (335 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (499 aa)
RB1RB transcriptional corepressor 1. (928 aa)
LOC113881562Ig-like domain-containing protein; Belongs to the MHC class II family. (253 aa)
TLNRD1Talin rod domain containing 1. (362 aa)
A0A4W2HUR1HORMA domain-containing protein. (197 aa)
MMP7Matrix metallopeptidase 7. (276 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (168 aa)
SLC25A6Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (410 aa)
LCKTyrosine-protein kinase. (509 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3874 aa)
VDAC1Voltage dependent anion channel 1. (283 aa)
XPO1Exportin 1. (1071 aa)
TBPL2TATA-box binding protein like 2. (325 aa)
CDC20Cell division cycle 20. (499 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
TBPL1TATA-box binding protein like 1. (186 aa)
E2F2E2F transcription factor 2. (437 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
E2F1E2F transcription factor 1. (437 aa)
A0A4W2H7Y7BH4_2 domain-containing protein. (195 aa)
CCNA2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (430 aa)
ETS1ETS proto-oncogene 1, transcription factor. (485 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (367 aa)
A0A4W2GYG4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (379 aa)
BCL2L1BH4_2 domain-containing protein. (233 aa)
CDKN2BCyclin dependent kinase inhibitor 2B. (138 aa)
NFATC3Nuclear factor of activated T cells 3. (1073 aa)
LOC113899187Uncharacterized protein. (202 aa)
JAK1Tyrosine-protein kinase. (1110 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
NFYBNuclear transcription factor Y subunit beta. (207 aa)
A0A4W2GF22DOC domain-containing protein. (83 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
CRTC3CREB regulated transcription coactivator 3. (619 aa)
MAPK10Mitogen-activated protein kinase. (425 aa)
A0A4W2G5Q0Protein kinase domain-containing protein. (79 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (809 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (260 aa)
CREB5cAMP responsive element binding protein 5. (538 aa)
MSX1Msh homeobox 1. (366 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (447 aa)
VDAC2Uncharacterized protein. (294 aa)
PIK3R2Uncharacterized protein. (724 aa)
AKT1Non-specific serine/threonine protein kinase. (747 aa)
ELK4ETS transcription factor ELK4. (478 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (155 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (774 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (135 aa)
TNFRSF13CTNF receptor superfamily member 13C. (215 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
KAT2BLysine acetyltransferase 2B. (990 aa)
ITGB2Integrin beta. (769 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
A0A4W2F1Y8CYCLIN domain-containing protein; Belongs to the cyclin family. (250 aa)
A0A4W2F1C1Uncharacterized protein. (295 aa)
IL6Interleukin 6. (208 aa)
JAK3Tyrosine-protein kinase. (1181 aa)
PIK3R3Uncharacterized protein. (461 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (530 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
A0A4W2ES87IGv domain-containing protein. (140 aa)
A0A4W2ES53Ig-like domain-containing protein. (222 aa)
A0A4W2ES23Uncharacterized protein. (128 aa)
A0A4W2ERP9Ig-like domain-containing protein. (331 aa)
A0A4W2ERN6Ig-like domain-containing protein. (127 aa)
CSF2Colony stimulating factor 2. (143 aa)
A0A4W2ERJ9Ig-like domain-containing protein. (181 aa)
A0A4W2ERJ1Ig-like domain-containing protein. (174 aa)
A0A4W2ERG5Ig-like domain-containing protein. (136 aa)
A0A4W2ERF0Ig-like domain-containing protein. (150 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (452 aa)
A0A4W2EQH2Ig-like domain-containing protein. (102 aa)
A0A4W2EQG3Ig-like domain-containing protein. (217 aa)
A0A4W2EQB9Ig-like domain-containing protein. (189 aa)
A0A4W2EQA0Ig-like domain-containing protein. (207 aa)
A0A4W2EQ96Ig-like domain-containing protein. (157 aa)
A0A4W2EQ07Ig-like domain-containing protein. (95 aa)
A0A4W2EPY6Ig-like domain-containing protein. (102 aa)
TBPUncharacterized protein. (318 aa)
A0A4W2EP15Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (241 aa)
LOC113899279Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (118 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1259 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (568 aa)
BUB1BUncharacterized protein. (1062 aa)
CDK4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (303 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (404 aa)
RANBP1RAN binding protein 1. (206 aa)
SPI1Spi-1 proto-oncogene. (384 aa)
RELBRELB proto-oncogene, NF-kB subunit. (647 aa)
A0A4W2EJS6Sushi domain-containing protein. (323 aa)
CCNB2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (398 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (333 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (292 aa)
A0A4W2EEW1Homeobox domain-containing protein. (234 aa)
IL1R2Interleukin 1 receptor type 2. (400 aa)
IL1R1Interleukin 1 receptor type 1. (573 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (161 aa)
A0A4W2EDY1Ig-like domain-containing protein. (318 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
RANBP3LRAN binding protein 3 like. (466 aa)
AKT3AKT serine/threonine kinase 3. (564 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (411 aa)
A0A4W2EBF5GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (428 aa)
IL2RAInterleukin 2 receptor subunit alpha. (275 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1197 aa)
CD40CD40 molecule. (280 aa)
CREB3cAMP responsive element binding protein 3. (365 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
A0A4W2E8M1BH4_2 domain-containing protein. (173 aa)
SPIBETS domain-containing protein. (259 aa)
CDC20BCell division cycle 20B. (514 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (657 aa)
CHEK2Checkpoint kinase 2. (534 aa)
A0A4W2E497MHC_I-like_Ag-recog domain-containing protein; Belongs to the MHC class I family. (243 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1253 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (953 aa)
ATF6BActivating transcription factor 6 beta. (718 aa)
LOC113881774Ig-like domain-containing protein. (304 aa)
MSX2Msh homeobox 2. (267 aa)
IL2RGFibronectin type-III domain-containing protein. (403 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1096 aa)
TNFRSF1ATNF receptor superfamily member 1A. (471 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (768 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
A0A4W2DXK0HORMA domain-containing protein. (258 aa)
A0A4W2DX15Ig-like domain-containing protein. (199 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (393 aa)
CDC23Cell division cycle 23. (607 aa)
LOC113882059Ig-like domain-containing protein; Belongs to the MHC class I family. (366 aa)
A0A4W2DW81Ig-like domain-containing protein; Belongs to the MHC class I family. (343 aa)
A0A4W2DVS8Ig-like domain-containing protein. (529 aa)
BUB3BUB3 mitotic checkpoint protein. (343 aa)
PPP3CCSerine/threonine-protein phosphatase. (531 aa)
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (297 aa)
EGR2Early growth response 2. (485 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3054 aa)
A0A4W2DS38Uncharacterized protein. (409 aa)
A0A4W2DRK4IGv domain-containing protein. (83 aa)
CHEK1Checkpoint kinase 1. (677 aa)
ERASES cell expressed Ras. (185 aa)
SMAD4Mothers against decapentaplegic homolog. (553 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (888 aa)
A0A4W2DPN4TORC_N domain-containing protein. (169 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
A0A4W2DP28GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
A0A4W2DNG0Ig-like domain-containing protein. (591 aa)
A0A4W2DNF6Ig-like domain-containing protein. (488 aa)
A0A4W2DMM0IGv domain-containing protein. (177 aa)
TRBV24-1T cell receptor beta variable 24-1. (97 aa)
NFATC4Nuclear factor of activated T cells 4. (979 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1165 aa)
A0A4W2DMB6Ig-like domain-containing protein. (172 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (456 aa)
A0A4W2DK85Ig-like domain-containing protein. (111 aa)
A0A4W2DK77Ig-like domain-containing protein. (193 aa)
IL2RBInterleukin 2 receptor subunit beta. (659 aa)
CREBBPCREB binding protein. (2435 aa)
MAD2L1HORMA domain-containing protein. (215 aa)
FDPSFarnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (421 aa)
ETS2Protein C-ets-2; Transcription factor; Belongs to the ETS family. (471 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (542 aa)
CRTC2Uncharacterized protein. (693 aa)
PTTG1Uncharacterized protein. (202 aa)
CDKN2ACyclin dependent kinase inhibitor 2A. (160 aa)
TCF3Transcription factor 3. (640 aa)
A0A4W2DCT4Uncharacterized protein. (194 aa)
A0A4W2DBM4Ig-like domain-containing protein; Belongs to the MHC class I family. (475 aa)
TLN2Talin 2. (2542 aa)
CRTC1CREB regulated transcription coactivator 1. (653 aa)
LOC113896623Uncharacterized protein. (202 aa)
CANXCalnexin. (593 aa)
TLN1Talin 1. (2539 aa)
A0A4W2D801Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (274 aa)
ATF2Activating transcription factor 2. (447 aa)
A0A4W2D7C1Ig-like domain-containing protein. (127 aa)
A0A4W2D760Ig-like domain-containing protein. (128 aa)
A0A4W2D724Ig-like domain-containing protein. (177 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
A0A4W2D709Ig-like domain-containing protein. (165 aa)
A0A4W2D704Ig-like domain-containing protein. (150 aa)
A0A4W2D608BH4_2 domain-containing protein. (238 aa)
A0A4W2D5P0DUF1968 domain-containing protein. (225 aa)
A0A4W2D5H8Ig-like domain-containing protein. (237 aa)
A0A4W2D5G0Ig-like domain-containing protein. (106 aa)
A0A4W2D5F7Ig-like domain-containing protein. (182 aa)
A0A4W2D597Ig-like domain-containing protein. (112 aa)
A0A4W2D552Ig-like domain-containing protein. (153 aa)
A0A4W2D547Ig-like domain-containing protein. (146 aa)
CDC26Cell division cycle 26. (85 aa)
A0A4W2D520Ig-like domain-containing protein. (202 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
MAP2K1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa)
CSDE1Cold shock domain containing E1. (844 aa)
ESPL1Extra spindle pole bodies like 1, separase. (2100 aa)
A0A4W2D326Uncharacterized protein. (165 aa)
A0A4W2D2W9Ig-like domain-containing protein. (261 aa)
A0A4W2D2T1Ig-like domain-containing protein. (127 aa)
A0A4W2D2S8Ig-like domain-containing protein. (127 aa)
A0A4W2D2S0Ig-like domain-containing protein. (174 aa)
A0A4W2D2R2Ig-like domain-containing protein. (118 aa)
A0A4W2D2L8Ig-like domain-containing protein. (147 aa)
ANAPC1Anaphase promoting complex subunit 1. (1958 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
A0A4W2D0I4Ig-like domain-containing protein. (112 aa)
A0A4W2D0G3Ig-like domain-containing protein. (151 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
A0A4W2D0E0Ig-like domain-containing protein. (136 aa)
A0A4W2D0D6Ig-like domain-containing protein. (177 aa)
A0A4W2D095Ig-like domain-containing protein. (143 aa)
A0A4W2D056Ig-like domain-containing protein. (153 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1096 aa)
A0A4W2CY87Uncharacterized protein. (97 aa)
CDC16Cell division cycle 16. (620 aa)
ANAPC7Anaphase promoting complex subunit 7. (598 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
MAPK1Mitogen-activated protein kinase. (634 aa)
CD4CD4 molecule. (455 aa)
NFATC2Nuclear factor of activated T cells 2. (914 aa)
LTBRLymphotoxin beta receptor. (428 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (560 aa)
A0A4W2CK57Ig-like domain-containing protein; Belongs to the MHC class I family. (375 aa)
SRFSerum response factor. (509 aa)
TGFB1Transforming growth factor beta 1. (443 aa)
AKT2AKT serine/threonine kinase 2. (603 aa)
A0A4W2CHX7BH4_2 domain-containing protein. (233 aa)
A0A4W2CFU3Ig-like domain-containing protein. (259 aa)
A0A4W2CFU1Protein kinase domain-containing protein. (79 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1125 aa)
ZFP36ZFP36 ring finger protein. (325 aa)
RANGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
STAT5BSignal transducer and activator of transcription. (787 aa)
CDC27Cell division cycle 27. (831 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1507 aa)
A0A4W2CCQ9Uncharacterized protein. (303 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
ANAPC11RING-type domain-containing protein. (84 aa)
ANAPC5Anaphase promoting complex subunit 5. (755 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
GPS2G protein pathway suppressor 2. (327 aa)
A0A4W2C624Ig-like domain-containing protein; Belongs to the MHC class I family. (327 aa)
A0A4W2C618Ig-like domain-containing protein; Belongs to the MHC class I family. (353 aa)
A0A4W2C595Ig-like domain-containing protein; Belongs to the MHC class I family. (325 aa)
A0A4W2C3Y8Uncharacterized protein. (69 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (412 aa)
A0A4W2C2X4Ig-like domain-containing protein; Belongs to the MHC class I family. (356 aa)
NFKB2Nuclear factor kappa B subunit 2. (900 aa)
LOC113882062Ig-like domain-containing protein; Belongs to the MHC class I family. (365 aa)
LOC113881805Ig-like domain-containing protein; Belongs to the MHC class I family. (374 aa)
A0A4W2C1X2Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa)
A0A4W2C1N1MHC_I-like_Ag-recog domain-containing protein. (218 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
LTALymphotoxin alpha; Belongs to the tumor necrosis factor family. (204 aa)
ANAPC10DOC domain-containing protein. (327 aa)
A0A4W2C1F6Uncharacterized protein. (278 aa)
HLA-DOBMajor histocompatibility complex, class II, DO beta. (271 aa)
ATF4Activating transcription factor 4. (348 aa)
EP300E1A binding protein p300. (2411 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (253 aa)
ELK1ETS transcription factor ELK1. (432 aa)
HLA-DQB1Major histocompatibility complex, class II, DQ beta 1. (269 aa)
SLC25A4Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (318 aa)
A0A4W2BXT5Ig-like domain-containing protein. (260 aa)
CD3DCD3d molecule. (167 aa)
SLC25A31Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
A0A4W2BVZ1Uncharacterized protein. (101 aa)
PPP3CBSerine/threonine-protein phosphatase. (524 aa)
CD3ECD3e molecule. (197 aa)
VDAC3Voltage dependent anion channel 3. (284 aa)
A0A4W2BUF7DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (531 aa)
VAC14VAC14 component of PIKFYVE complex. (783 aa)
SMAD2Mothers against decapentaplegic homolog. (626 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
A0A4W2BS58RING-type domain-containing protein. (81 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1117 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (421 aa)
E2F3E2F transcription factor 3. (465 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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