Your Input: | |
| | APC | APC regulator of WNT signaling pathway. (2912 aa) |
| | E2F3 | E2F transcription factor 3. (465 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | RASSF1 | Ras association domain family member 1. (340 aa) |
| | BCL2 | BCL2 apoptosis regulator. (229 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | PLAU | Plasminogen activator, urokinase. (433 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (224 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | PIM1 | Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (313 aa) |
| | EP300 | E1A binding protein p300. (2411 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) |
| | SLC7A1 | Solute carrier family 7 member 1. (629 aa) |
| | TNXB | Uncharacterized protein. (710 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) |
| | A0A4W2C4Q6 | Uncharacterized protein. (167 aa) |
| | PDGFA | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (401 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | TRIM71 | Tripartite motif containing 71. (876 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1209 aa) |
| | DICER1 | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1998 aa) |
| | MMP16 | Matrix metallopeptidase 16. (607 aa) |
| | CDC25A | Cell division cycle 25A. (525 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) |
| | A0A4W2CEF6 | Integrin beta; Belongs to the integrin beta chain family. (784 aa) |
| | MDM4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (491 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa) |
| | A0A4W2CHT2 | Uncharacterized protein. (1744 aa) |
| | VIM | Vimentin; Belongs to the intermediate filament family. (466 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (781 aa) |
| | SHC4 | SHC adaptor protein 4. (630 aa) |
| | RECK | Reversion inducing cysteine rich protein with kazal motifs. (970 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (634 aa) |
| | CYP24A1 | Cytochrome P450 family 24 subfamily A member 1; Belongs to the cytochrome P450 family. (561 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (302 aa) |
| | A0A4W2CQV1 | Uncharacterized protein. (185 aa) |
| | ZFPM2 | Zinc finger protein, FOG family member 2. (1151 aa) |
| | CD44 | CD44 molecule (Indian blood group). (850 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa) |
| | MDM2 | MDM2 proto-oncogene. (689 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa) |
| | ABL1 | Tyrosine-protein kinase. (1151 aa) |
| | IRS2 | Insulin receptor substrate 2. (1325 aa) |
| | HDAC5 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1162 aa) |
| | EZR | Ezrin. (638 aa) |
| | FGFR3 | Fibroblast growth factor receptor. (804 aa) |
| | BCL2L11 | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (195 aa) |
| | RPS6KA5 | Non-specific serine/threonine protein kinase. (945 aa) |
| | ZEB1 | Zinc finger E-box binding homeobox 1. (1177 aa) |
| | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (779 aa) |
| | CSDE1 | Cold shock domain containing E1. (844 aa) |
| | MAP2K1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa) |
| | MCL1 | Uncharacterized protein. (350 aa) |
| | A0A4W2D9I6 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | ADAM15 | ADAM metallopeptidase domain 15. (908 aa) |
| | A0A4W2DED5 | Uncharacterized protein; Belongs to the tropomyosin family. (320 aa) |
| | NOTCH3 | Notch receptor 3. (2313 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa) |
| | A0A4W2DG11 | Uncharacterized protein. (1289 aa) |
| | DNMT3A | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (957 aa) |
| | CDC25C | Cell division cycle 25C. (477 aa) |
| | CREBBP | CREB binding protein. (2435 aa) |
| | ITGA5 | Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1164 aa) |
| | FOXP1 | Fork-head domain-containing protein. (691 aa) |
| | SOX4 | SRY-box transcription factor 4. (501 aa) |
| | HMOX1 | Heme oxygenase 1. (302 aa) |
| | ST14 | Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (855 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | ERAS | ES cell expressed Ras. (185 aa) |
| | CRK | CRK proto-oncogene, adaptor protein. (376 aa) |
| | UBE2I | Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (158 aa) |
| | ABCC1 | ATP binding cassette subfamily C member 1. (1544 aa) |
| | A0A4W2DS38 | Uncharacterized protein. (409 aa) |
| | SIRT1 | Sirtuin 1. (734 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3054 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1356 aa) |
| | NOTCH1 | Notch receptor 1. (2533 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | A0A4W2DXS4 | RING-type domain-containing protein. (131 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | SERPINB5 | Serpin family B member 5; Belongs to the serpin family. (398 aa) |
| | ERBB2 | Erb-b2 receptor tyrosine kinase 2. (1710 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1335 aa) |
| | DDIT4 | DNA damage inducible transcript 4. (285 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (394 aa) |
| | IGF2BP1 | Insulin like growth factor 2 mRNA binding protein 1. (577 aa) |
| | NOTCH4 | Notch receptor 4. (1992 aa) |
| | A0A4W2E0B1 | Stathmin; Belongs to the stathmin family. (141 aa) |
| | PAK4 | Non-specific serine/threonine protein kinase. (593 aa) |
| | A0A4W2E3F9 | Uncharacterized protein. (374 aa) |
| | TNN | Tenascin N. (1296 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | CDC25B | Cell division cycle 25B. (574 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (428 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (411 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (771 aa) |
| | BRCA1 | BRCA1 DNA repair associated. (1941 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | HDAC1 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (513 aa) |
| | MET | MET proto-oncogene, receptor tyrosine kinase. (1384 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (161 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa) |
| | TNR | Tenascin R. (1358 aa) |
| | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (539 aa) |
| | HMGA2 | Uncharacterized protein. (109 aa) |
| | A0A4W2EHH7 | Uncharacterized protein. (91 aa) |
| | BMF | Bcl2 modifying factor. (184 aa) |
| | THBS1 | Thrombospondin 1. (1170 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | EFNA5 | Ephrin A5; Belongs to the ephrin family. (254 aa) |
| | TNC | Tenascin C. (2384 aa) |
| | HNRNPK | Uncharacterized protein. (464 aa) |
| | NOTCH2 | Notch receptor 2. (2471 aa) |
| | HOXD10 | Homeobox D10. (410 aa) |
| | A0A4W2EUV9 | Ephrin RBD domain-containing protein; Belongs to the ephrin family. (449 aa) |
| | APC2 | APC regulator of WNT signaling pathway 2. (2264 aa) |
| | A0A4W2EVH5 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1130 aa) |
| | PIK3R3 | Uncharacterized protein. (461 aa) |
| | A0A4W2EZ96 | Uncharacterized protein. (1258 aa) |
| | CCNG1 | CYCLIN domain-containing protein; Belongs to the cyclin family. (295 aa) |
| | GLS | Glutaminase. (675 aa) |
| | ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1336 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1098 aa) |
| | MARCKS | Myristoylated alanine rich protein kinase C substrate. (333 aa) |
| | SHC1 | SHC adaptor protein 1. (584 aa) |
| | EFNA1 | Ephrin A1; Belongs to the ephrin family. (325 aa) |
| | EFNA4 | Ephrin A4; Belongs to the ephrin family. (204 aa) |
| | SLC45A3 | Solute carrier family 45 member 3. (550 aa) |
| | EFNA3 | Ephrin RBD domain-containing protein; Belongs to the ephrin family. (238 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | PIK3R2 | Uncharacterized protein. (724 aa) |
| | MAP2K2 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (447 aa) |
| | FSCN2 | Fascin. (492 aa) |
| | PDCD4 | Programmed cell death 4. (469 aa) |
| | FSCN1 | Fascin. (493 aa) |
| | MMP9 | Matrix metallopeptidase 9. (712 aa) |
| | IGF2BP3 | Insulin like growth factor 2 mRNA binding protein 3. (580 aa) |
| | RDX | Radixin. (624 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | SOX11 | Transcription factor SOX. (451 aa) |
| | COMMD3 | RING-type domain-containing protein. (469 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) |
| | TIMP3 | TIMP metallopeptidase inhibitor 3. (318 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) |
| | SOX12 | Transcription factor SOX. (314 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | A0A4W2GYG4 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (379 aa) |
| | DNMT3B | DNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (862 aa) |
| | STMN1 | Uncharacterized protein. (295 aa) |
| | E2F1 | E2F transcription factor 1. (437 aa) |
| | KIF23 | Kinesin family member 23; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1026 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | E2F2 | E2F transcription factor 2. (437 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | HDAC2 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa) |
| | CDCA5 | Cell division cycle associated 5. (253 aa) |
| | GLS2 | Glutaminase 2. (602 aa) |
| | ZEB2 | Zinc finger E-box binding homeobox 2. (1191 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (499 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (974 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (456 aa) |
| | DNMT1 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1708 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1598 aa) |
| | SPRY2 | Sprouty RTK signaling antagonist 2. (315 aa) |
