STRINGSTRING
A0A4W2EX55 A0A4W2EX55 MAP2K1 MAP2K1 CSDE1 CSDE1 CDH1 CDH1 MAPK1 MAPK1 RET RET BAK1 BAK1 RXRA RXRA CTNNB1 CTNNB1 LOC113886173 LOC113886173 GADD45B GADD45B TFG TFG POLK POLK NCOA4 NCOA4 MAPK3 MAPK3 TP53 TP53 DDB2 DDB2 RXRB RXRB NTRK1 NTRK1 PAX8 PAX8 TCF7L1 TCF7L1 HRAS HRAS MYC MYC BAX BAX A0A4W2GYG4 A0A4W2GYG4 CCDC6 CCDC6 TCF7L2 TCF7L2 MAP2K2 MAP2K2 TCF7 TCF7 GADD45A GADD45A BRAF BRAF CDKN1A CDKN1A CCND1 CCND1 LEF1 LEF1 TPR TPR KRAS KRAS ERAS ERAS NRAS NRAS RXRG RXRG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A4W2EX55Uncharacterized protein. (119 aa)
MAP2K1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa)
CSDE1Cold shock domain containing E1. (844 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (883 aa)
MAPK1Mitogen-activated protein kinase. (634 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1114 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
RXRARetinoid X receptor alpha. (657 aa)
CTNNB1Catenin beta 1. (774 aa)
LOC113886173Uncharacterized protein; Belongs to the tropomyosin family. (248 aa)
GADD45BGrowth arrest and DNA damage inducible beta. (160 aa)
TFGTrafficking from ER to golgi regulator. (401 aa)
POLKDNA polymerase kappa. (911 aa)
NCOA4Nuclear receptor coactivator 4. (631 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (456 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (499 aa)
DDB2Damage specific DNA binding protein 2. (426 aa)
RXRBRetinoid X receptor beta. (536 aa)
NTRK1Tyrosine-protein kinase receptor. (821 aa)
PAX8Paired box 8. (457 aa)
TCF7L1Transcription factor 7 like 1. (588 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
A0A4W2GYG4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (379 aa)
CCDC6Coiled-coil domain containing 6. (477 aa)
TCF7L2Transcription factor 7 like 2. (652 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (447 aa)
TCF7Transcription factor 7. (473 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (165 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (805 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (161 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (428 aa)
LEF1Lymphoid enhancer binding factor 1. (430 aa)
TPRTranslocated promoter region, nuclear basket protein. (2444 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
ERASES cell expressed Ras. (185 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
RXRGRetinoid X receptor gamma. (463 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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