STRINGSTRING
LOC113886173 LOC113886173 SGCB SGCB ITGA6 ITGA6 A0A4W2DBA5 A0A4W2DBA5 A0A4W2DBA0 A0A4W2DBA0 ITGA4 ITGA4 ITGA11 ITGA11 ITGB7 ITGB7 TNNT1 TNNT1 PRKAG1 PRKAG1 CACNB3 CACNB3 ATP2A3 ATP2A3 PRKAB1 PRKAB1 TPM2 TPM2 DES DES SLC8A1 SLC8A1 SLC39A12 SLC39A12 LAMA2 LAMA2 CACNG6 CACNG6 TNNT2 TNNT2 CACNB2 CACNB2 TGFB1 TGFB1 ITGA8 ITGA8 RYR2 RYR2 CACNG5 CACNG5 CACNG1 CACNG1 A0A4W2CEF6 A0A4W2CEF6 ATP2A2 ATP2A2 ITGA2 ITGA2 ACE ACE MYH8 MYH8 MYH3 MYH3 ITGB4 ITGB4 MYH2 MYH2 CACNA1C CACNA1C A0A4W2BVX1 A0A4W2BVX1 DAG1 DAG1 ATP2A1 ATP2A1 LAMA1 LAMA1 A0A4W2BRL6 A0A4W2BRL6 TPM3 TPM3 CACNA2D3 CACNA2D3 ITGA5 ITGA5 CACNG2 CACNG2 TNNT3 TNNT3 CACNA2D1 CACNA2D1 ITGA9 ITGA9 CACNA1D CACNA1D SGCG SGCG CACNB1 CACNB1 A0A4W2DWM2 A0A4W2DWM2 CACNA1S CACNA1S CACNB4 CACNB4 ACTB ACTB ITGA3 ITGA3 ITGA1 ITGA1 LOC113878341 LOC113878341 A0A4W2E4P6 A0A4W2E4P6 TNNI3 TNNI3 SLC8A2 SLC8A2 ACTBL2 ACTBL2 CACNG4 CACNG4 CACNA2D2 CACNA2D2 TNF TNF PRKAG3 PRKAG3 UTRN UTRN ITGB5 ITGB5 MYH6 MYH6 TGFB3 TGFB3 ITGA10 ITGA10 A0A4W2EUH7 A0A4W2EUH7 LRRC66 LRRC66 A0A4W2EX55 A0A4W2EX55 ITGB6 ITGB6 IL6 IL6 ITGB8 ITGB8 LMNA LMNA ITGA7 ITGA7 MYH15 MYH15 TNNC1 TNNC1 ITGAV ITGAV LOC113876999 LOC113876999 CACNG8 CACNG8 CACNG3 CACNG3 ITGB1 ITGB1 MYL2 MYL2 TPM1 TPM1 ACTL8 ACTL8 TGFB2 TGFB2 SGCA SGCA PRKAA1 PRKAA1 PRKAG2 PRKAG2 ACTC1 ACTC1 MYBPC3 MYBPC3 IGF1 IGF1 A0A4W2I4Y5 A0A4W2I4Y5 CACNG7 CACNG7 SGCD SGCD EDN1 EDN1 SLC8A3 SLC8A3 AGT AGT A0A4W2DED5 A0A4W2DED5 CACNA1F CACNA1F PRKAA2 PRKAA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC113886173Uncharacterized protein; Belongs to the tropomyosin family. (248 aa)
SGCBSarcoglycan beta. (317 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
A0A4W2DBA5Uncharacterized protein. (563 aa)
A0A4W2DBA0Uncharacterized protein. (699 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1338 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1189 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (873 aa)
TNNT1Troponin T1, slow skeletal type. (321 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (330 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (496 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1044 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
TPM2Tropomyosin 2; Belongs to the tropomyosin family. (284 aa)
DESDesmin; Belongs to the intermediate filament family. (470 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
SLC39A12Solute carrier family 39 member 12. (754 aa)
LAMA2Laminin subunit alpha 2. (3122 aa)
CACNG6Uncharacterized protein. (388 aa)
TNNT2Troponin T2, cardiac type. (369 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (658 aa)
TGFB1Transforming growth factor beta 1. (443 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1062 aa)
RYR2Ryanodine receptor 2. (4967 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (424 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (223 aa)
A0A4W2CEF6Integrin beta; Belongs to the integrin beta chain family. (784 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1179 aa)
ACEAngiotensin-converting enzyme; Belongs to the peptidase M2 family. (1549 aa)
MYH8Myosin heavy chain 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
MYH3Myosin heavy chain 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa)
ITGB4Integrin beta. (1804 aa)
MYH2Myosin heavy chain 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1965 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2194 aa)
A0A4W2BVX1EF-hand domain-containing protein. (121 aa)
DAG1Dystroglycan 1. (1096 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1010 aa)
LAMA1Laminin subunit alpha 1. (3131 aa)
A0A4W2BRL6Uncharacterized protein. (57 aa)
TPM3Uncharacterized protein. (287 aa)
CACNA2D3Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (1091 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1164 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (300 aa)
TNNT3Troponin T3, fast skeletal type. (261 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1106 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1034 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2183 aa)
SGCGSarcoglycan gamma. (309 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (643 aa)
A0A4W2DWM2VWFA domain-containing protein. (988 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1872 aa)
CACNB4SH3 domain-containing protein. (502 aa)
ACTBActin beta. (375 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1065 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
LOC113878341Angiotensin-converting enzyme. (742 aa)
A0A4W2E4P6VGCC_alpha2 domain-containing protein. (283 aa)
TNNI3Troponin I3, cardiac type. (212 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (922 aa)
ACTBL2Actin beta like 2. (376 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (321 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1156 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (333 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (535 aa)
UTRNUtrophin. (3432 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (800 aa)
MYH6Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1967 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (452 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1330 aa)
A0A4W2EUH7Uncharacterized protein. (5571 aa)
LRRC66Leucine rich repeat containing 66. (857 aa)
A0A4W2EX55Uncharacterized protein. (119 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
IL6Interleukin 6. (208 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (772 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (664 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1181 aa)
MYH15Myosin heavy chain 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1964 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (161 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
LOC113876999Myosin heavy chain 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (426 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
MYL2Myosin light chain 2. (166 aa)
TPM1Uncharacterized protein; Belongs to the tropomyosin family. (326 aa)
ACTL8Actin like 8; Belongs to the actin family. (365 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
SGCASarcoglycan alpha. (433 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (565 aa)
ACTC1Actin alpha cardiac muscle 1. (377 aa)
MYBPC3Myosin binding protein C, cardiac. (1269 aa)
IGF1Insulin like growth factor 1. (188 aa)
A0A4W2I4Y5Uncharacterized protein; Belongs to the tropomyosin family. (222 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
SGCDSarcoglycan delta. (289 aa)
EDN1Endothelin 1. (202 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (928 aa)
AGTAngiotensinogen; Belongs to the serpin family. (476 aa)
A0A4W2DED5Uncharacterized protein; Belongs to the tropomyosin family. (320 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1929 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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