STRINGSTRING
ITGB1 ITGB1 CTNNA3 CTNNA3 ACTL8 ACTL8 SGCA SGCA GJA1 GJA1 TCF7L1 TCF7L1 CACNG7 CACNG7 ITGA8 ITGA8 RYR2 RYR2 CACNG5 CACNG5 CACNG1 CACNG1 A0A4W2CEF6 A0A4W2CEF6 ATP2A2 ATP2A2 CTNNA2 CTNNA2 ACTN3 ACTN3 ITGA2 ITGA2 ITGB4 ITGB4 CACNA1C CACNA1C EPPK1 EPPK1 DAG1 DAG1 CDH2 CDH2 ATP2A1 ATP2A1 LAMA1 LAMA1 DSG2 DSG2 CTNNB1 CTNNB1 CACNA1F CACNA1F DES DES SLC8A1 SLC8A1 ATP2A3 ATP2A3 SLC39A12 SLC39A12 LAMA2 LAMA2 CACNG6 CACNG6 CACNB2 CACNB2 JUP JUP SLC8A3 SLC8A3 CACNB3 CACNB3 ITGB7 ITGB7 ITGA11 ITGA11 ITGA4 ITGA4 ITGA6 ITGA6 SGCB SGCB SGCD SGCD CACNA2D3 CACNA2D3 PKP2 PKP2 ITGA5 ITGA5 CACNG2 CACNG2 CACNA2D1 CACNA2D1 DSC2 DSC2 ITGA9 ITGA9 CACNA1D CACNA1D SGCG SGCG CACNB1 CACNB1 ACTN2 ACTN2 A0A4W2DWM2 A0A4W2DWM2 CACNA1S CACNA1S CACNB4 CACNB4 ACTB ACTB ITGA3 ITGA3 ITGA1 ITGA1 LEF1 LEF1 A0A4W2E4P6 A0A4W2E4P6 SLC8A2 SLC8A2 ACTBL2 ACTBL2 DSP DSP CACNG4 CACNG4 CACNA2D2 CACNA2D2 PLEC PLEC UTRN UTRN ITGB5 ITGB5 ITGA10 ITGA10 LRRC66 LRRC66 ITGB6 ITGB6 ITGB8 ITGB8 LMNA LMNA ITGA7 ITGA7 ITGAV ITGAV TCF7 TCF7 CTNNA1 CTNNA1 TCF7L2 TCF7L2 CACNG8 CACNG8 CACNG3 CACNG3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
CTNNA3Catenin alpha 3. (895 aa)
ACTL8Actin like 8; Belongs to the actin family. (365 aa)
SGCASarcoglycan alpha. (433 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (383 aa)
TCF7L1Transcription factor 7 like 1. (588 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1062 aa)
RYR2Ryanodine receptor 2. (4967 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (424 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (223 aa)
A0A4W2CEF6Integrin beta; Belongs to the integrin beta chain family. (784 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
CTNNA2Catenin alpha 2. (953 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (901 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1179 aa)
ITGB4Integrin beta. (1804 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2194 aa)
EPPK1Epiplakin 1. (4997 aa)
DAG1Dystroglycan 1. (1096 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (1318 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1010 aa)
LAMA1Laminin subunit alpha 1. (3131 aa)
DSG2Desmoglein 2. (1202 aa)
CTNNB1Catenin beta 1. (774 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1929 aa)
DESDesmin; Belongs to the intermediate filament family. (470 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1044 aa)
SLC39A12Solute carrier family 39 member 12. (754 aa)
LAMA2Laminin subunit alpha 2. (3122 aa)
CACNG6Uncharacterized protein. (388 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (658 aa)
JUPJunction plakoglobin. (745 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (928 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (496 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (873 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1189 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1338 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
SGCBSarcoglycan beta. (317 aa)
SGCDSarcoglycan delta. (289 aa)
CACNA2D3Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (1091 aa)
PKP2Plakophilin 2. (839 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1164 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (300 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1106 aa)
DSC2Desmocollin 2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (906 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1034 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2183 aa)
SGCGSarcoglycan gamma. (309 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (643 aa)
ACTN2Actinin alpha 2. (894 aa)
A0A4W2DWM2VWFA domain-containing protein. (988 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1872 aa)
CACNB4SH3 domain-containing protein. (502 aa)
ACTBActin beta. (375 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1065 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
LEF1Lymphoid enhancer binding factor 1. (430 aa)
A0A4W2E4P6VGCC_alpha2 domain-containing protein. (283 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (922 aa)
ACTBL2Actin beta like 2. (376 aa)
DSPDesmoplakin. (2889 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (321 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1156 aa)
PLECPlectin. (4671 aa)
UTRNUtrophin. (3432 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (800 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1330 aa)
LRRC66Leucine rich repeat containing 66. (857 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (772 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (664 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1181 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
TCF7Transcription factor 7. (473 aa)
CTNNA1Catenin alpha 1. (919 aa)
TCF7L2Transcription factor 7 like 2. (652 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (426 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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