STRINGSTRING
MYL2 MYL2 TPM1 TPM1 ACTL8 ACTL8 PRKACB PRKACB TGFB2 TGFB2 SGCA SGCA ACTC1 ACTC1 MYBPC3 MYBPC3 IGF1 IGF1 A0A4W2I4Y5 A0A4W2I4Y5 AGT AGT TNNT1 TNNT1 ITGB7 ITGB7 ITGA11 ITGA11 ITGA4 ITGA4 ADCY4 ADCY4 A0A4W2DBA0 A0A4W2DBA0 A0A4W2DBA5 A0A4W2DBA5 A0A4W2DC91 A0A4W2DC91 ITGA6 ITGA6 SGCB SGCB A0A4W2DED5 A0A4W2DED5 TPM3 TPM3 CACNA2D3 CACNA2D3 ITGA5 ITGA5 CACNG2 CACNG2 TNNT3 TNNT3 CACNA2D1 CACNA2D1 ITGA9 ITGA9 CACNA1D CACNA1D SGCG SGCG CACNB1 CACNB1 A0A4W2DWM2 A0A4W2DWM2 CACNA1S CACNA1S A0A4W2DX14 A0A4W2DX14 CACNB4 CACNB4 ACTB ACTB ADCY7 ADCY7 ITGA3 ITGA3 ADRB1 ADRB1 ITGA1 ITGA1 ADCY8 ADCY8 A0A4W2E4P6 A0A4W2E4P6 TNNI3 TNNI3 SLC8A2 SLC8A2 ACTBL2 ACTBL2 ADCY1 ADCY1 A0A4W2EA01 A0A4W2EA01 CACNG4 CACNG4 CACNA2D2 CACNA2D2 TNF TNF UTRN UTRN ADCY3 ADCY3 ADCY5 ADCY5 ITGB5 ITGB5 MYH6 MYH6 TGFB3 TGFB3 ITGA10 ITGA10 A0A4W2EUH7 A0A4W2EUH7 LRRC66 LRRC66 A0A4W2EX55 A0A4W2EX55 ITGB6 ITGB6 ITGB8 ITGB8 LMNA LMNA ITGA7 ITGA7 MYH15 MYH15 TNNC1 TNNC1 ITGAV ITGAV LOC113876999 LOC113876999 CACNG8 CACNG8 PRKACA PRKACA CACNG3 CACNG3 ITGB1 ITGB1 CACNG7 CACNG7 SGCD SGCD SLC8A3 SLC8A3 CACNB3 CACNB3 ADCY6 ADCY6 PTRHD1 PTRHD1 ADCY2 ADCY2 GNAS GNAS ATP2A3 ATP2A3 TPM2 TPM2 DES DES SLC8A1 SLC8A1 SLC39A12 SLC39A12 LAMA2 LAMA2 CACNG6 CACNG6 TNNT2 TNNT2 CACNB2 CACNB2 TGFB1 TGFB1 ITGA8 ITGA8 RYR2 RYR2 CACNG5 CACNG5 CACNG1 CACNG1 A0A4W2CEF6 A0A4W2CEF6 PLN PLN ATP2A2 ATP2A2 A0A4W2CAS0 A0A4W2CAS0 A0A4W2CAP7 A0A4W2CAP7 A0A4W2CAP3 A0A4W2CAP3 ITGA2 ITGA2 MYH8 MYH8 MYH3 MYH3 ITGB4 ITGB4 MYH2 MYH2 CACNA1C CACNA1C A0A4W2BWE6 A0A4W2BWE6 A0A4W2BVX1 A0A4W2BVX1 A0A4W2BVW3 A0A4W2BVW3 DAG1 DAG1 ATP2A1 ATP2A1 A0A4W2BTN2 A0A4W2BTN2 A0A4W2BTN1 A0A4W2BTN1 LAMA1 LAMA1 A0A4W2BRL6 A0A4W2BRL6 LOC113886173 LOC113886173 ADCY9 ADCY9 CACNA1F CACNA1F
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MYL2Myosin light chain 2. (166 aa)
TPM1Uncharacterized protein; Belongs to the tropomyosin family. (326 aa)
ACTL8Actin like 8; Belongs to the actin family. (365 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (367 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
SGCASarcoglycan alpha. (433 aa)
ACTC1Actin alpha cardiac muscle 1. (377 aa)
MYBPC3Myosin binding protein C, cardiac. (1269 aa)
IGF1Insulin like growth factor 1. (188 aa)
A0A4W2I4Y5Uncharacterized protein; Belongs to the tropomyosin family. (222 aa)
AGTAngiotensinogen; Belongs to the serpin family. (476 aa)
TNNT1Troponin T1, slow skeletal type. (321 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (873 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1189 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1338 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
A0A4W2DBA0Uncharacterized protein. (699 aa)
A0A4W2DBA5Uncharacterized protein. (563 aa)
A0A4W2DC91Uncharacterized protein. (241 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
SGCBSarcoglycan beta. (317 aa)
A0A4W2DED5Uncharacterized protein; Belongs to the tropomyosin family. (320 aa)
TPM3Uncharacterized protein. (287 aa)
CACNA2D3Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (1091 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1164 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (300 aa)
TNNT3Troponin T3, fast skeletal type. (261 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1106 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1034 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2183 aa)
SGCGSarcoglycan gamma. (309 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (643 aa)
A0A4W2DWM2VWFA domain-containing protein. (988 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1872 aa)
A0A4W2DX14Ig-like domain-containing protein. (160 aa)
CACNB4SH3 domain-containing protein. (502 aa)
ACTBActin beta. (375 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1096 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1065 aa)
ADRB1Adrenoceptor beta 1. (514 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1253 aa)
A0A4W2E4P6VGCC_alpha2 domain-containing protein. (283 aa)
TNNI3Troponin I3, cardiac type. (212 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (922 aa)
ACTBL2Actin beta like 2. (376 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1197 aa)
A0A4W2EA01Uncharacterized protein. (48 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (321 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1156 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (333 aa)
UTRNUtrophin. (3432 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1259 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (800 aa)
MYH6Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1967 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (452 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1330 aa)
A0A4W2EUH7Uncharacterized protein. (5571 aa)
LRRC66Leucine rich repeat containing 66. (857 aa)
A0A4W2EX55Uncharacterized protein. (119 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (772 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (664 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1181 aa)
MYH15Myosin heavy chain 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1964 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (161 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
LOC113876999Myosin heavy chain 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (426 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
SGCDSarcoglycan delta. (289 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (928 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (496 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1096 aa)
GNASGNAS complex locus. (1004 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1044 aa)
TPM2Tropomyosin 2; Belongs to the tropomyosin family. (284 aa)
DESDesmin; Belongs to the intermediate filament family. (470 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
SLC39A12Solute carrier family 39 member 12. (754 aa)
LAMA2Laminin subunit alpha 2. (3122 aa)
CACNG6Uncharacterized protein. (388 aa)
TNNT2Troponin T2, cardiac type. (369 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (658 aa)
TGFB1Transforming growth factor beta 1. (443 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1062 aa)
RYR2Ryanodine receptor 2. (4967 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (424 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (223 aa)
A0A4W2CEF6Integrin beta; Belongs to the integrin beta chain family. (784 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
A0A4W2CAS0Ig-like domain-containing protein. (223 aa)
A0A4W2CAP7Ig-like domain-containing protein. (213 aa)
A0A4W2CAP3Ig-like domain-containing protein. (182 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1179 aa)
MYH8Myosin heavy chain 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
MYH3Myosin heavy chain 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa)
ITGB4Integrin beta. (1804 aa)
MYH2Myosin heavy chain 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1965 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2194 aa)
A0A4W2BWE6Ig-like domain-containing protein. (204 aa)
A0A4W2BVX1EF-hand domain-containing protein. (121 aa)
A0A4W2BVW3Ig-like domain-containing protein. (218 aa)
DAG1Dystroglycan 1. (1096 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1010 aa)
A0A4W2BTN2Ig-like domain-containing protein. (130 aa)
A0A4W2BTN1Uncharacterized protein. (508 aa)
LAMA1Laminin subunit alpha 1. (3131 aa)
A0A4W2BRL6Uncharacterized protein. (57 aa)
LOC113886173Uncharacterized protein; Belongs to the tropomyosin family. (248 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1117 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1929 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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