(26 nodes) RNA Polymerase II Transcription Elongation network (Chlamydomonas reinhardtii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	A0A2K3CSD5	Uncharacterized protein. (495 aa)
	RPB1	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1812 aa)
	A0A2K3CWA4	TFIIS central domain-containing protein. (230 aa)
	A0A2K3CX59	Uncharacterized protein. (913 aa)
	A0A2K3D117	Uncharacterized protein. (1303 aa)
	A0A2K3D431	Uncharacterized protein. (541 aa)
	RPB3	RPOLD domain-containing protein. (372 aa)
	A0A2K3DAI6	TFIIS N-terminal domain-containing protein. (529 aa)
	A0A2K3DF59	S1 motif domain-containing protein. (1794 aa)
	A0A2K3DII3	RPOL4c domain-containing protein. (140 aa)
	A0A2K3DQ88	Uncharacterized protein. (2757 aa)
	A0A2K3DQM7	Uncharacterized protein. (1616 aa)
	A0A2K3DVX6	EAF domain-containing protein. (476 aa)
	A0A2K3DY83	Uncharacterized protein. (1285 aa)
	A0A2K3DYN4	Plus3 domain-containing protein. (642 aa)
	RPB2	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1616 aa)
	A0A2K3E176	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (471 aa)
	A0A2K3E2J1	Uncharacterized protein. (484 aa)
	A0A2K3E6M5	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (698 aa)
	A8HQJ4_CHLRE	Global transcription factor. (1188 aa)
	RPB11	DNA-directed RNA polymerase II, 13.6 kDa polypeptide. (115 aa)
	A8I2N9_CHLRE	Transcription initiation factor. (122 aa)
	RPB9	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (118 aa)
	A8IRG8_CHLRE	Predicted protein. (753 aa)
	RPB7A	DNA-directed RNA polymerase II, 19 kDa polypeptide. (176 aa)
	A8J1C2_CHLRE	Predicted protein. (348 aa)

Your Current Organism:

Chlamydomonas reinhardtii

NCBI taxonomy Id: 3055
Other names: C. reinhardtii, Chlamydomonas smithii, Chlamydomonas smithii R.W.Howshaw & H.Ettl, SAG 53.72 [[Chlamydomonas smithii]], SAG 54.72 [[Chlamydomonas smithii]], UTEX 90

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A2K3CSD5	A0A2K3CWA4	A0A2K3CSD5	A0A2K3CWA4	Uncharacterized protein.	TFIIS central domain-containing protein.	0.686
A0A2K3CSD5	A0A2K3D117	A0A2K3CSD5	A0A2K3D117	Uncharacterized protein.	Uncharacterized protein.	0.832
A0A2K3CSD5	A0A2K3D431	A0A2K3CSD5	A0A2K3D431	Uncharacterized protein.	Uncharacterized protein.	0.999
A0A2K3CSD5	A0A2K3DAI6	A0A2K3CSD5	A0A2K3DAI6	Uncharacterized protein.	TFIIS N-terminal domain-containing protein.	0.845
A0A2K3CSD5	A0A2K3DF59	A0A2K3CSD5	A0A2K3DF59	Uncharacterized protein.	S1 motif domain-containing protein.	0.871
A0A2K3CSD5	A0A2K3DII3	A0A2K3CSD5	A0A2K3DII3	Uncharacterized protein.	RPOL4c domain-containing protein.	0.850
A0A2K3CSD5	A0A2K3DQ88	A0A2K3CSD5	A0A2K3DQ88	Uncharacterized protein.	Uncharacterized protein.	0.806
A0A2K3CSD5	A0A2K3DQM7	A0A2K3CSD5	A0A2K3DQM7	Uncharacterized protein.	Uncharacterized protein.	0.604
A0A2K3CSD5	A0A2K3DVX6	A0A2K3CSD5	A0A2K3DVX6	Uncharacterized protein.	EAF domain-containing protein.	0.454
A0A2K3CSD5	A0A2K3DY83	A0A2K3CSD5	A0A2K3DY83	Uncharacterized protein.	Uncharacterized protein.	0.999
A0A2K3CSD5	A0A2K3DYN4	A0A2K3CSD5	A0A2K3DYN4	Uncharacterized protein.	Plus3 domain-containing protein.	0.994
A0A2K3CSD5	A0A2K3E176	A0A2K3CSD5	A0A2K3E176	Uncharacterized protein.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.957
A0A2K3CSD5	A0A2K3E2J1	A0A2K3CSD5	A0A2K3E2J1	Uncharacterized protein.	Uncharacterized protein.	0.999
A0A2K3CSD5	A0A2K3E6M5	A0A2K3CSD5	A0A2K3E6M5	Uncharacterized protein.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.957
A0A2K3CSD5	A8HQJ4_CHLRE	A0A2K3CSD5	A8HQJ4	Uncharacterized protein.	Global transcription factor.	0.888
A0A2K3CSD5	A8I2N9_CHLRE	A0A2K3CSD5	A8I2N9	Uncharacterized protein.	Transcription initiation factor.	0.959
A0A2K3CSD5	A8IRG8_CHLRE	A0A2K3CSD5	A8IRG8	Uncharacterized protein.	Predicted protein.	0.711
A0A2K3CSD5	A8J1C2_CHLRE	A0A2K3CSD5	A8J1C2	Uncharacterized protein.	Predicted protein.	0.686
A0A2K3CSD5	RPB1	A0A2K3CSD5	A0A2K3CV27	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.409
A0A2K3CSD5	RPB11	A0A2K3CSD5	A8HRP7	Uncharacterized protein.	DNA-directed RNA polymerase II, 13.6 kDa polypeptide.	0.818

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