(52 nodes) RNA polymerase II, holoenzyme network (Chlamydomonas reinhardtii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RPB1	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1812 aa)
	A0A2K3CY93	Uncharacterized protein. (399 aa)
	A0A2K3CYT7	CYCLIN domain-containing protein; Belongs to the cyclin family. (425 aa)
	A0A2K3D0J1	Uncharacterized protein. (2155 aa)
	A0A2K3D2G5	TFIIE beta domain-containing protein. (357 aa)
	A0A2K3D431	Uncharacterized protein. (541 aa)
	A0A2K3D4K9	WD_REPEATS_REGION domain-containing protein. (788 aa)
	A0A2K3D4R7	TFIID_20kDa domain-containing protein. (403 aa)
	A0A2K3D7I9	Uncharacterized protein. (1157 aa)
	A0A2K3D7R2	Uncharacterized protein. (860 aa)
	A0A2K3D855	WD_REPEATS_REGION domain-containing protein. (316 aa)
	A0A2K3D8S0	TFIIE domain-containing protein. (601 aa)
	A0A2K3D8T0	CID domain-containing protein. (702 aa)
	RPB3	RPOLD domain-containing protein. (372 aa)
	A0A2K3D9G8	Uncharacterized protein. (2560 aa)
	A0A2K3DBB9	Uncharacterized protein. (561 aa)
	A0A2K3DCB3	BSD domain-containing protein. (694 aa)
	A0A2K3DCN7	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (558 aa)
	RPB5	Uncharacterized protein. (202 aa)
	A0A2K3DII3	RPOL4c domain-containing protein. (140 aa)
	A0A2K3DIN8	Uncharacterized protein. (937 aa)
	A0A2K3DL83	TAF domain-containing protein. (796 aa)
	A0A2K3DQ55	Uncharacterized protein. (640 aa)
	A0A2K3DQM7	Uncharacterized protein. (1616 aa)
	A0A2K3DQN1	Uncharacterized protein. (1338 aa)
	A0A2K3DQQ5	BTP domain-containing protein. (415 aa)
	A0A2K3DRT5	Protein kinase domain-containing protein. (1704 aa)
	A0A2K3DUR3	WD_REPEATS_REGION domain-containing protein. (489 aa)
	TFB4	Uncharacterized protein. (307 aa)
	TF2H2	General transcription factor IIH subunit. (432 aa)
	A0A2K3DY83	Uncharacterized protein. (1285 aa)
	A0A2K3DYN4	Plus3 domain-containing protein. (642 aa)
	A0A2K3DZR4	TFIIF_beta_N domain-containing protein. (131 aa)
	RPB2	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1616 aa)
	A0A2K3E2E7	Uncharacterized protein. (110 aa)
	A0A2K3E2J1	Uncharacterized protein. (484 aa)
	RPB6	Uncharacterized protein. (132 aa)
	A0A2K3E5E8	TAFII55_N domain-containing protein. (210 aa)
	A0A2K3E5G4	TAFII28 domain-containing protein. (235 aa)
	A0A2K3E786	Uncharacterized protein. (2540 aa)
	RPB11	DNA-directed RNA polymerase II, 13.6 kDa polypeptide. (115 aa)
	RPB10	DNA-directed RNA polymerases I/II/III subunit. (79 aa)
	A8ICC6_CHLRE	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (119 aa)
	RPB9	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (118 aa)
	RPB7A	DNA-directed RNA polymerase II, 19 kDa polypeptide. (176 aa)
	RPB12	Subunit f DNA-directed RNA polymerase. (58 aa)
	CDKD1	CDK activating kinase; Belongs to the protein kinase superfamily. (353 aa)
	A8J8H6_CHLRE	Predicted protein. (154 aa)
	A8JBD7_CHLRE	Predicted protein. (179 aa)
	A8JFR8_CHLRE	Predicted protein. (142 aa)
	rpoC1A	DNA-directed RNA polymerase subunit beta' N-terminal section; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily. (603 aa)
	A0A2K3CSD5	Uncharacterized protein. (495 aa)

Your Current Organism:

Chlamydomonas reinhardtii

NCBI taxonomy Id: 3055
Other names: C. reinhardtii, Chlamydomonas smithii, Chlamydomonas smithii R.W.Howshaw & H.Ettl, SAG 53.72 [[Chlamydomonas smithii]], SAG 54.72 [[Chlamydomonas smithii]], UTEX 90

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A2K3CSD5	A0A2K3D431	A0A2K3CSD5	A0A2K3D431	Uncharacterized protein.	Uncharacterized protein.	0.999
A0A2K3CSD5	A0A2K3D7I9	A0A2K3CSD5	A0A2K3D7I9	Uncharacterized protein.	Uncharacterized protein.	0.604
A0A2K3CSD5	A0A2K3D855	A0A2K3CSD5	A0A2K3D855	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.861
A0A2K3CSD5	A0A2K3DBB9	A0A2K3CSD5	A0A2K3DBB9	Uncharacterized protein.	Uncharacterized protein.	0.409
A0A2K3CSD5	A0A2K3DII3	A0A2K3CSD5	A0A2K3DII3	Uncharacterized protein.	RPOL4c domain-containing protein.	0.850
A0A2K3CSD5	A0A2K3DQM7	A0A2K3CSD5	A0A2K3DQM7	Uncharacterized protein.	Uncharacterized protein.	0.604
A0A2K3CSD5	A0A2K3DY83	A0A2K3CSD5	A0A2K3DY83	Uncharacterized protein.	Uncharacterized protein.	0.999
A0A2K3CSD5	A0A2K3DYN4	A0A2K3CSD5	A0A2K3DYN4	Uncharacterized protein.	Plus3 domain-containing protein.	0.994
A0A2K3CSD5	A0A2K3E2E7	A0A2K3CSD5	A0A2K3E2E7	Uncharacterized protein.	Uncharacterized protein.	0.850
A0A2K3CSD5	A0A2K3E2J1	A0A2K3CSD5	A0A2K3E2J1	Uncharacterized protein.	Uncharacterized protein.	0.999
A0A2K3CSD5	A0A2K3E786	A0A2K3CSD5	A0A2K3E786	Uncharacterized protein.	Uncharacterized protein.	0.604
A0A2K3CSD5	RPB1	A0A2K3CSD5	A0A2K3CV27	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.409
A0A2K3CSD5	RPB10	A0A2K3CSD5	A8HSJ0	Uncharacterized protein.	DNA-directed RNA polymerases I/II/III subunit.	0.850
A0A2K3CSD5	RPB11	A0A2K3CSD5	A8HRP7	Uncharacterized protein.	DNA-directed RNA polymerase II, 13.6 kDa polypeptide.	0.818
A0A2K3CSD5	RPB12	A0A2K3CSD5	A8ITN4	Uncharacterized protein.	Subunit f DNA-directed RNA polymerase.	0.604
A0A2K3CSD5	RPB2	A0A2K3CSD5	A0A2K3E045	Uncharacterized protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.594
A0A2K3CSD5	RPB3	A0A2K3CSD5	A0A2K3D929	Uncharacterized protein.	RPOLD domain-containing protein.	0.878
A0A2K3CSD5	RPB5	A0A2K3CSD5	A0A2K3DF68	Uncharacterized protein.	Uncharacterized protein.	0.855
A0A2K3CSD5	RPB6	A0A2K3CSD5	A0A2K3E4T4	Uncharacterized protein.	Uncharacterized protein.	0.857
A0A2K3CSD5	RPB7A	A0A2K3CSD5	A8ISK2	Uncharacterized protein.	DNA-directed RNA polymerase II, 19 kDa polypeptide.	0.711

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