(68 nodes) Aldolase-type TIM barrel network (Chlamydomonas reinhardtii)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	A0A2K3D1A8	Elp3 domain-containing protein. (688 aa)
	ASB2	Phosphoribosylanthranilate isomerase. (265 aa)
	SHKA1	Phospho-2-dehydro-3-deoxyheptonate aldolase. (502 aa)
	A8J6R7_CHLRE	Predicted protein. (391 aa)
	A8JAP7_CHLRE	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (507 aa)
	A8JBW0_CHLRE	Predicted protein. (435 aa)
	FBA1	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (391 aa)
	HIS6	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide isomerase. (305 aa)
	A8JHN1_CHLRE	Fe-S oxidoreductase. (420 aa)
	NPT1	Nicotinamide phosphoribosyltransferase. (543 aa)
	PHR1	7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase. (1106 aa)
	GYX1	Glycolate oxidase. (384 aa)
	TIM	Chloroplast triosephosphate isomerase. (282 aa)
	HydG	Fe-hydrogenase assembly protein. (567 aa)
	HydEF	Iron hydrogenase assembly protein. (1151 aa)
	A8J0N3_CHLRE	Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (320 aa)
	TAL2	Transaldolase. (399 aa)
	RPE1	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (265 aa)
	FBA2	Fructose-1,6-bisphosphate aldolase. (370 aa)
	ALAD	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (390 aa)
	A0A2K3D197	IGPS domain-containing protein. (340 aa)
	A0A2K3DT17	Uncharacterized protein. (796 aa)
	FBA3	Uncharacterized protein. (377 aa)
	A0A2K3DSL1	Radical_SAM domain-containing protein. (149 aa)
	A0A2K3DRG0	Glyco_hydro_114 domain-containing protein. (771 aa)
	A0A2K3DQ79	DHO_dh domain-containing protein. (422 aa)
	A0A2K3DUZ8	tRNA-dihydrouridine(47) synthase [NAD(P)(+)]. (798 aa)
	A0A2K3DX36	Elp3 domain-containing protein. (656 aa)
	A0A2K3DYR6	Radical_SAM domain-containing protein. (516 aa)
	PYR4	Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (415 aa)
	A0A2K3DZU3	Oxidored_FMN domain-containing protein. (465 aa)
	A0A2K3E0Y6	Radical_SAM domain-containing protein. (584 aa)
	DPS1	4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. (349 aa)
	A0A2K3E2V3	Elp3 domain-containing protein. (493 aa)
	LIP1P	Lipoyl synthase, chloroplastic; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (430 aa)
	FBA4	Uncharacterized protein. (308 aa)
	RPE2	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (258 aa)
	A0A2K3E6D1	Alpha-galactosidase. (646 aa)
	A0A2K3E6Q5	Radical_SAM domain-containing protein. (471 aa)
	TAL1	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (399 aa)
	A0A2K3E7K7	Radical_SAM domain-containing protein. (793 aa)
	PYR5	OMPdecase domain-containing protein. (514 aa)
	A0A2K3E7Z6	Oxidored_FMN domain-containing protein. (410 aa)
	A0A2K3DPX7	Uncharacterized protein. (541 aa)
	A0A2K3DMR7	Uncharacterized protein. (439 aa)
	A0A2K3DMK8	Uncharacterized protein. (946 aa)
	A0A2K3DMI3	Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (686 aa)
	SHKD1	Uncharacterized protein. (566 aa)
	A0A2K3DGU0	Uncharacterized protein. (1175 aa)
	LIPA1	Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (452 aa)
	A0A2K3DDU6	Uncharacterized protein. (414 aa)
	A0A2K3D9C3	Uncharacterized protein. (514 aa)
	A0A2K3D8R8	Uncharacterized protein; Belongs to the HisA/HisF family. (483 aa)
	A0A2K3D713	Uncharacterized protein. (820 aa)
	TSA1	Uncharacterized protein; Belongs to the TrpA family. (296 aa)
	GSF1	Glutamine amidotransferase type-2 domain-containing protein. (1629 aa)
	A0A2K3D2E1	Uncharacterized protein. (388 aa)
	FSA1	Uncharacterized protein. (294 aa)
	SIP1	Uncharacterized protein. (1184 aa)
	A0A2K3CWI9	Uncharacterized protein. (755 aa)
	A0A2K3CWZ6	SOR_SNZ domain-containing protein; Belongs to the PdxS/SNZ family. (296 aa)
	A0A2K3CXP1	Uncharacterized protein. (1049 aa)
	A0A2K3CY54	Flavodoxin-like domain-containing protein. (912 aa)
	IGS1	IGPS domain-containing protein. (291 aa)
	A0A2K3D064	DHO_dh domain-containing protein. (431 aa)
	GSN1	Glutamine amidotransferase type-2 domain-containing protein. (2251 aa)
	A0A2K3D165	Uncharacterized protein. (427 aa)
	A0A2K3D1S8	Pyruvate carboxyltransferase domain-containing protein. (362 aa)

Your Current Organism:

Chlamydomonas reinhardtii

NCBI taxonomy Id: 3055
Other names: C. reinhardtii, Chlamydomonas smithii, Chlamydomonas smithii R.W.Howshaw & H.Ettl, SAG 53.72 [[Chlamydomonas smithii]], SAG 54.72 [[Chlamydomonas smithii]], UTEX 90

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A2K3CWZ6	A0A2K3D8R8	A0A2K3CWZ6	A0A2K3D8R8	SOR_SNZ domain-containing protein; Belongs to the PdxS/SNZ family.	Uncharacterized protein; Belongs to the HisA/HisF family.	0.602
A0A2K3CWZ6	GSF1	A0A2K3CWZ6	A0A2K3D3L7	SOR_SNZ domain-containing protein; Belongs to the PdxS/SNZ family.	Glutamine amidotransferase type-2 domain-containing protein.	0.479
A0A2K3CWZ6	GSN1	A0A2K3CWZ6	A0A2K3D151	SOR_SNZ domain-containing protein; Belongs to the PdxS/SNZ family.	Glutamine amidotransferase type-2 domain-containing protein.	0.479
A0A2K3CWZ6	IGS1	A0A2K3CWZ6	A0A2K3D004	SOR_SNZ domain-containing protein; Belongs to the PdxS/SNZ family.	IGPS domain-containing protein.	0.644
A0A2K3CY54	A0A2K3DX36	A0A2K3CY54	A0A2K3DX36	Flavodoxin-like domain-containing protein.	Elp3 domain-containing protein.	0.431
A0A2K3D064	A0A2K3D8R8	A0A2K3D064	A0A2K3D8R8	DHO_dh domain-containing protein.	Uncharacterized protein; Belongs to the HisA/HisF family.	0.413
A0A2K3D064	A8JAP7_CHLRE	A0A2K3D064	A8JAP7	DHO_dh domain-containing protein.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.564
A0A2K3D064	HIS6	A0A2K3D064	A8JDM6	DHO_dh domain-containing protein.	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide isomerase.	0.401
A0A2K3D064	IGS1	A0A2K3D064	A0A2K3D004	DHO_dh domain-containing protein.	IGPS domain-containing protein.	0.701
A0A2K3D064	PYR5	A0A2K3D064	A0A2K3E7W9	DHO_dh domain-containing protein.	OMPdecase domain-containing protein.	0.962
A0A2K3D064	TIM	A0A2K3D064	Q5S7Y5	DHO_dh domain-containing protein.	Chloroplast triosephosphate isomerase.	0.442
A0A2K3D165	A0A2K3D2E1	A0A2K3D165	A0A2K3D2E1	Uncharacterized protein.	Uncharacterized protein.	0.470
A0A2K3D165	A0A2K3DPX7	A0A2K3D165	A0A2K3DPX7	Uncharacterized protein.	Uncharacterized protein.	0.414
A0A2K3D197	A0A2K3D8R8	A0A2K3D197	A0A2K3D8R8	IGPS domain-containing protein.	Uncharacterized protein; Belongs to the HisA/HisF family.	0.614
A0A2K3D197	ASB2	A0A2K3D197	A8J650	IGPS domain-containing protein.	Phosphoribosylanthranilate isomerase.	0.951
A0A2K3D197	HIS6	A0A2K3D197	A8JDM6	IGPS domain-containing protein.	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide isomerase.	0.866
A0A2K3D197	IGS1	A0A2K3D197	A0A2K3D004	IGPS domain-containing protein.	IGPS domain-containing protein.	0.997
A0A2K3D197	PYR5	A0A2K3D197	A0A2K3E7W9	IGPS domain-containing protein.	OMPdecase domain-containing protein.	0.414
A0A2K3D197	TIM	A0A2K3D197	Q5S7Y5	IGPS domain-containing protein.	Chloroplast triosephosphate isomerase.	0.451
A0A2K3D197	TSA1	A0A2K3D197	A0A2K3D4M6	IGPS domain-containing protein.	Uncharacterized protein; Belongs to the TrpA family.	0.996

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