(15 nodes) Mixed, incl. Calreticulin family, and Protein folding in endoplasmic reticulum network (Otolemur garnettii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CALR3	Calreticulin. (384 aa)
	H0WTW2_OTOGA	ANK_REP_REGION domain-containing protein. (226 aa)
	DNAJC10	DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. (794 aa)
	PDIA4	Protein disulfide-isomerase A4. (645 aa)
	PDIA6	Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family. (458 aa)
	ERO1A	Endoplasmic reticulum oxidoreductase 1 alpha. (469 aa)
	ERP27	Endoplasmic reticulum protein 27. (273 aa)
	CLGN	Calmegin. (527 aa)
	PDIA2	Protein disulfide isomerase family A member 2. (460 aa)
	ERO1B	Endoplasmic reticulum oxidoreductase 1 beta. (467 aa)
	CANX	Calnexin. (592 aa)
	HSP90B1	HATPase_c domain-containing protein. (804 aa)
	PDIA5	Protein disulfide isomerase family A member 5. (522 aa)
	H0XWF5_OTOGA	Calreticulin. (414 aa)
	LOC100966026	Uncharacterized protein. (243 aa)

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CALR3	CANX	ENSOGAP00000005214	ENSOGAP00000014092	Calreticulin.	Calnexin.	0.938
CALR3	CLGN	ENSOGAP00000005214	ENSOGAP00000011103	Calreticulin.	Calmegin.	0.898
CALR3	DNAJC10	ENSOGAP00000005214	ENSOGAP00000006239	Calreticulin.	DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.	0.858
CALR3	ERP27	ENSOGAP00000005214	ENSOGAP00000009423	Calreticulin.	Endoplasmic reticulum protein 27.	0.714
CALR3	H0WTW2_OTOGA	ENSOGAP00000005214	ENSOGAP00000005619	Calreticulin.	ANK_REP_REGION domain-containing protein.	0.911
CALR3	HSP90B1	ENSOGAP00000005214	ENSOGAP00000015229	Calreticulin.	HATPase_c domain-containing protein.	0.983
CALR3	PDIA2	ENSOGAP00000005214	ENSOGAP00000013361	Calreticulin.	Protein disulfide isomerase family A member 2.	0.918
CALR3	PDIA4	ENSOGAP00000005214	ENSOGAP00000008218	Calreticulin.	Protein disulfide-isomerase A4.	0.970
CALR3	PDIA5	ENSOGAP00000005214	ENSOGAP00000017352	Calreticulin.	Protein disulfide isomerase family A member 5.	0.714
CALR3	PDIA6	ENSOGAP00000005214	ENSOGAP00000008721	Calreticulin.	Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family.	0.931
CANX	CALR3	ENSOGAP00000014092	ENSOGAP00000005214	Calnexin.	Calreticulin.	0.938
CANX	DNAJC10	ENSOGAP00000014092	ENSOGAP00000006239	Calnexin.	DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.	0.859
CANX	ERO1A	ENSOGAP00000014092	ENSOGAP00000008940	Calnexin.	Endoplasmic reticulum oxidoreductase 1 alpha.	0.444
CANX	ERO1B	ENSOGAP00000014092	ENSOGAP00000013910	Calnexin.	Endoplasmic reticulum oxidoreductase 1 beta.	0.444
CANX	ERP27	ENSOGAP00000014092	ENSOGAP00000009423	Calnexin.	Endoplasmic reticulum protein 27.	0.639
CANX	H0WTW2_OTOGA	ENSOGAP00000014092	ENSOGAP00000005619	Calnexin.	ANK_REP_REGION domain-containing protein.	0.947
CANX	H0XWF5_OTOGA	ENSOGAP00000014092	ENSOGAP00000020448	Calnexin.	Calreticulin.	0.938
CANX	HSP90B1	ENSOGAP00000014092	ENSOGAP00000015229	Calnexin.	HATPase_c domain-containing protein.	0.946
CANX	PDIA2	ENSOGAP00000014092	ENSOGAP00000013361	Calnexin.	Protein disulfide isomerase family A member 2.	0.811
CANX	PDIA4	ENSOGAP00000014092	ENSOGAP00000008218	Calnexin.	Protein disulfide-isomerase A4.	0.880