94 items (Otolemur garnettii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PPP1R12B	Protein phosphatase 1 regulatory subunit. (982 aa)
	DIAPH1	Diaphanous related formin 1. (1207 aa)
	RHOBTB1	Rho related BTB domain containing 1. (696 aa)
	GIT1	GIT ArfGAP 1. (772 aa)
	CHN1	Chimaerin; GTPase-activating protein for p21-rac. (437 aa)
	PPP1R16B	Protein phosphatase 1 regulatory subunit 16B. (568 aa)
	DIAPH3	Diaphanous related formin 3. (861 aa)
	ANLN	Anillin actin binding protein. (1126 aa)
	ARHGAP15	Rho GTPase activating protein 15. (474 aa)
	ARHGEF7	Rho guanine nucleotide exchange factor 7. (784 aa)
	RHOU	Ras homolog family member U. (258 aa)
	CDC42BPB	CDC42 binding protein kinase beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1712 aa)
	PREX1	Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1654 aa)
	GMIP	GEM interacting protein. (967 aa)
	ARHGEF37	Rho guanine nucleotide exchange factor 37. (661 aa)
	WAS	WASP actin nucleation promoting factor. (503 aa)
	H0WNP2_OTOGA	Uncharacterized protein. (1162 aa)
	RND2	Rho family GTPase 2. (227 aa)
	TIAM1	T cell lymphoma invasion and metastasis 1. (1495 aa)
	RAC2	Rac family small GTPase 2. (192 aa)
	MDM1	Mdm1 nuclear protein. (716 aa)
	NCK1	Cytoplasmic protein. (377 aa)
	PLEKHG2	Pleckstrin homology and RhoGEF domain containing G2. (1309 aa)
	ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor 6. (850 aa)
	PAK2	Non-specific serine/threonine protein kinase. (524 aa)
	CHN2	Chimaerin; GTPase-activating protein for p21-rac. (468 aa)
	RHOH	Ras homolog family member H. (191 aa)
	CIT	Citron rho-interacting serine/threonine kinase. (1423 aa)
	PKN2	Protein kinase N2. (967 aa)
	PPP1R12C	Protein phosphatase 1 regulatory subunit 12C. (672 aa)
	MYO9A	Myosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2629 aa)
	IQGAP1	IQ motif containing GTPase activating protein 1. (1681 aa)
	RHOF	Ras homolog family member F, filopodia associated. (211 aa)
	IQGAP3	IQ motif containing GTPase activating protein 3. (1635 aa)
	PAK5	P21 (RAC1) activated kinase 5. (652 aa)
	PAK1	Non-specific serine/threonine protein kinase. (544 aa)
	MYO9B	Myosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2159 aa)
	ROCK2	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1359 aa)
	PAK6	Non-specific serine/threonine protein kinase. (682 aa)
	PPP1R14A	Protein phosphatase 1 regulatory inhibitor subunit 14A. (147 aa)
	PKN1	Protein kinase N1. (939 aa)
	RASL12	RAS like family 12. (267 aa)
	ARHGDIB	Rho GDP dissociation inhibitor beta. (200 aa)
	RHOD	Ras homolog family member D. (228 aa)
	PPP1R12A	Protein phosphatase 1 regulatory subunit. (1030 aa)
	ABR	ABR activator of RhoGEF and GTPase. (813 aa)
	FNBP1L	Formin binding protein 1 like. (607 aa)
	ROCK1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1365 aa)
	PAK4	Non-specific serine/threonine protein kinase. (587 aa)
	GIT2	GIT ArfGAP 2. (759 aa)
	RAC3	Rac family small GTPase 3. (192 aa)
	ARHGAP45	Rho GTPase activating protein 45. (1153 aa)
	SH3PXD2B	SH3 and PX domains 2B. (910 aa)
	CCDC174	Coiled-coil domain containing 174. (466 aa)
	IQGAP2	IQ motif containing GTPase activating protein 2. (1402 aa)
	DIAPH2	Diaphanous related formin 2. (1085 aa)
	CDC42	Uncharacterized protein. (191 aa)
	TRIO	Trio Rho guanine nucleotide exchange factor. (3051 aa)
	ARHGAP1	Rho GTPase activating protein 1. (462 aa)
	ARHGAP29	Rho GTPase activating protein 29. (1268 aa)
	RHOBTB2	Rho related BTB domain containing 2. (728 aa)
	ARHGDIG	Rho GDP dissociation inhibitor gamma (Predicted). (225 aa)
	KALRN	Kalirin RhoGEF kinase. (2985 aa)
	ARHGEF4	Rho guanine nucleotide exchange factor 4. (547 aa)
	PPP1CB	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (322 aa)
	PAK3	Non-specific serine/threonine protein kinase. (559 aa)
	RERG	RAS like estrogen regulated growth inhibitor. (195 aa)
	ARHGAP12	Rho GTPase activating protein 12. (846 aa)
	RAC1	Rac family small GTPase 1. (156 aa)
	VAV2	Vav guanine nucleotide exchange factor 2. (713 aa)
	ARL8B	ADP ribosylation factor like GTPase 8B; Belongs to the small GTPase superfamily. Arf family. (246 aa)
	CLRN2	Clarin 2. (232 aa)
	FMNL1	Formin like 1. (1102 aa)
	C20orf96	Chromosome 20 open reading frame 96. (361 aa)
	PKN3	Protein kinase N3. (889 aa)
	RHOQ	Ras homolog family member Q. (205 aa)
	H0XNB5_OTOGA	RasGAP_C domain-containing protein. (161 aa)
	H0XS27_OTOGA	Uncharacterized protein. (373 aa)
	ARHGAP27	Rho GTPase activating protein 27. (888 aa)
	LOC100947706	Uncharacterized protein. (191 aa)
	TRIP10	Thyroid hormone receptor interactor 10. (618 aa)
	ARHGDIA	Rho GDP dissociation inhibitor alpha. (204 aa)
	ARL8A	ADP ribosylation factor like GTPase 8A; Belongs to the small GTPase superfamily. Arf family. (186 aa)
	RHOC	Ras homolog family member C. (193 aa)
	ARHGAP19	Rho-GAP domain-containing protein. (476 aa)
	PPP1CA	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
	DMPK	DM1 protein kinase. (629 aa)
	RHOB	Ras homolog family member B. (196 aa)
	H0XY59_OTOGA	Uncharacterized protein. (129 aa)
	RHOV	Ras homolog family member V. (236 aa)
	NCK2	Cytoplasmic protein. (380 aa)
	RHOJ	Ras homolog family member J. (214 aa)
	RHOA	Uncharacterized protein. (142 aa)
	FNBP1	Formin binding protein 1. (617 aa)

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABR	ARHGAP1	ENSOGAP00000009813	ENSOGAP00000012805	ABR activator of RhoGEF and GTPase.	Rho GTPase activating protein 1.	0.649
ABR	ARHGAP12	ENSOGAP00000009813	ENSOGAP00000014792	ABR activator of RhoGEF and GTPase.	Rho GTPase activating protein 12.	0.633
ABR	ARHGAP15	ENSOGAP00000009813	ENSOGAP00000001769	ABR activator of RhoGEF and GTPase.	Rho GTPase activating protein 15.	0.633
ABR	ARHGAP19	ENSOGAP00000009813	ENSOGAP00000019632	ABR activator of RhoGEF and GTPase.	Rho-GAP domain-containing protein.	0.605
ABR	ARHGAP27	ENSOGAP00000009813	ENSOGAP00000019049	ABR activator of RhoGEF and GTPase.	Rho GTPase activating protein 27.	0.633
ABR	ARHGAP29	ENSOGAP00000009813	ENSOGAP00000013136	ABR activator of RhoGEF and GTPase.	Rho GTPase activating protein 29.	0.605
ABR	ARHGAP45	ENSOGAP00000009813	ENSOGAP00000011350	ABR activator of RhoGEF and GTPase.	Rho GTPase activating protein 45.	0.605
ABR	ARL8A	ENSOGAP00000009813	ENSOGAP00000019124	ABR activator of RhoGEF and GTPase.	ADP ribosylation factor like GTPase 8A; Belongs to the small GTPase superfamily. Arf family.	0.450
ABR	ARL8B	ENSOGAP00000009813	ENSOGAP00000016297	ABR activator of RhoGEF and GTPase.	ADP ribosylation factor like GTPase 8B; Belongs to the small GTPase superfamily. Arf family.	0.450
ABR	C20orf96	ENSOGAP00000009813	ENSOGAP00000017223	ABR activator of RhoGEF and GTPase.	Chromosome 20 open reading frame 96.	0.450
ABR	CDC42	ENSOGAP00000009813	ENSOGAP00000012779	ABR activator of RhoGEF and GTPase.	Uncharacterized protein.	0.680
ABR	CDC42BPB	ENSOGAP00000009813	ENSOGAP00000002204	ABR activator of RhoGEF and GTPase.	CDC42 binding protein kinase beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.450
ABR	CHN1	ENSOGAP00000009813	ENSOGAP00000000798	ABR activator of RhoGEF and GTPase.	Chimaerin; GTPase-activating protein for p21-rac.	0.605
ABR	CHN2	ENSOGAP00000009813	ENSOGAP00000004848	ABR activator of RhoGEF and GTPase.	Chimaerin; GTPase-activating protein for p21-rac.	0.605
ABR	DMPK	ENSOGAP00000009813	ENSOGAP00000020200	ABR activator of RhoGEF and GTPase.	DM1 protein kinase.	0.450
ABR	GMIP	ENSOGAP00000009813	ENSOGAP00000002317	ABR activator of RhoGEF and GTPase.	GEM interacting protein.	0.605
ABR	LOC100947706	ENSOGAP00000009813	ENSOGAP00000019057	ABR activator of RhoGEF and GTPase.	Uncharacterized protein.	0.680
ABR	MDM1	ENSOGAP00000009813	ENSOGAP00000003850	ABR activator of RhoGEF and GTPase.	Mdm1 nuclear protein.	0.450
ABR	MYO9A	ENSOGAP00000009813	ENSOGAP00000005478	ABR activator of RhoGEF and GTPase.	Myosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.749
ABR	MYO9B	ENSOGAP00000009813	ENSOGAP00000007510	ABR activator of RhoGEF and GTPase.	Myosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.749