(12 nodes) Protein import into peroxisome matrix, and Plasmalogen biosynthesis network (Otolemur garnettii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HSDL2	Hydroxysteroid dehydrogenase like 2. (362 aa)
	EPHX2	Epoxide hydrolase 2. (555 aa)
	PEX12	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family. (359 aa)
	PEX5	Peroxisomal biogenesis factor 5. (661 aa)
	ECI2	Enoyl-CoA delta isomerase 2. (364 aa)
	AGPS	Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. (562 aa)
	SCP2	Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa)
	PEX5L	Peroxisomal biogenesis factor 5 like. (595 aa)
	FAM185A	Family with sequence similarity 185 member A. (299 aa)
	GNPAT	Dihydroxyacetone phosphate acyltransferase. (693 aa)
	PEX2	Peroxisomal biogenesis factor 2. (305 aa)
	PEX10	Peroxisomal biogenesis factor 10. (326 aa)

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGPS	ECI2	ENSOGAP00000011813	ENSOGAP00000010413	Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.	Enoyl-CoA delta isomerase 2.	0.421
AGPS	EPHX2	ENSOGAP00000011813	ENSOGAP00000002855	Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.	Epoxide hydrolase 2.	0.844
AGPS	FAM185A	ENSOGAP00000011813	ENSOGAP00000016287	Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.	Family with sequence similarity 185 member A.	0.756
AGPS	GNPAT	ENSOGAP00000011813	ENSOGAP00000017561	Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.	Dihydroxyacetone phosphate acyltransferase.	0.960
AGPS	HSDL2	ENSOGAP00000011813	ENSOGAP00000001918	Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.	Hydroxysteroid dehydrogenase like 2.	0.573
AGPS	PEX10	ENSOGAP00000011813	ENSOGAP00000022526	Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.	Peroxisomal biogenesis factor 10.	0.829
AGPS	PEX12	ENSOGAP00000011813	ENSOGAP00000003570	Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family.	0.825
AGPS	PEX2	ENSOGAP00000011813	ENSOGAP00000018708	Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.	Peroxisomal biogenesis factor 2.	0.737
AGPS	PEX5	ENSOGAP00000011813	ENSOGAP00000009630	Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.	Peroxisomal biogenesis factor 5.	0.888
AGPS	PEX5L	ENSOGAP00000011813	ENSOGAP00000012427	Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.	Peroxisomal biogenesis factor 5 like.	0.847
AGPS	SCP2	ENSOGAP00000011813	ENSOGAP00000011927	Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.	Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.889
ECI2	AGPS	ENSOGAP00000010413	ENSOGAP00000011813	Enoyl-CoA delta isomerase 2.	Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.	0.421
ECI2	EPHX2	ENSOGAP00000010413	ENSOGAP00000002855	Enoyl-CoA delta isomerase 2.	Epoxide hydrolase 2.	0.500
ECI2	FAM185A	ENSOGAP00000010413	ENSOGAP00000016287	Enoyl-CoA delta isomerase 2.	Family with sequence similarity 185 member A.	0.983
ECI2	HSDL2	ENSOGAP00000010413	ENSOGAP00000001918	Enoyl-CoA delta isomerase 2.	Hydroxysteroid dehydrogenase like 2.	0.976
ECI2	PEX10	ENSOGAP00000010413	ENSOGAP00000022526	Enoyl-CoA delta isomerase 2.	Peroxisomal biogenesis factor 10.	0.981
ECI2	PEX12	ENSOGAP00000010413	ENSOGAP00000003570	Enoyl-CoA delta isomerase 2.	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family.	0.982
ECI2	PEX2	ENSOGAP00000010413	ENSOGAP00000018708	Enoyl-CoA delta isomerase 2.	Peroxisomal biogenesis factor 2.	0.979
ECI2	PEX5	ENSOGAP00000010413	ENSOGAP00000009630	Enoyl-CoA delta isomerase 2.	Peroxisomal biogenesis factor 5.	0.990
ECI2	PEX5L	ENSOGAP00000010413	ENSOGAP00000012427	Enoyl-CoA delta isomerase 2.	Peroxisomal biogenesis factor 5 like.	0.990