node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BMP2 | BMP4 | ENSOGAP00000005672 | ENSOGAP00000020983 | Bone morphogenetic protein 2. | Bone morphogenetic protein 4 (Predicted). | 0.880 |
BMP2 | CTNNB1 | ENSOGAP00000005672 | ENSOGAP00000014470 | Bone morphogenetic protein 2. | Catenin beta 1. | 0.422 |
BMP2 | FGF8 | ENSOGAP00000005672 | ENSOGAP00000017738 | Bone morphogenetic protein 2. | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.457 |
BMP2 | WNT2 | ENSOGAP00000005672 | ENSOGAP00000012163 | Bone morphogenetic protein 2. | Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). | 0.429 |
BMP4 | BMP2 | ENSOGAP00000020983 | ENSOGAP00000005672 | Bone morphogenetic protein 4 (Predicted). | Bone morphogenetic protein 2. | 0.880 |
BMP4 | CTNNB1 | ENSOGAP00000020983 | ENSOGAP00000014470 | Bone morphogenetic protein 4 (Predicted). | Catenin beta 1. | 0.428 |
BMP4 | FGF10 | ENSOGAP00000020983 | ENSOGAP00000001025 | Bone morphogenetic protein 4 (Predicted). | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.497 |
BMP4 | FGF8 | ENSOGAP00000020983 | ENSOGAP00000017738 | Bone morphogenetic protein 4 (Predicted). | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.463 |
BMP4 | WNT2 | ENSOGAP00000020983 | ENSOGAP00000012163 | Bone morphogenetic protein 4 (Predicted). | Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). | 0.482 |
CTNNB1 | BMP2 | ENSOGAP00000014470 | ENSOGAP00000005672 | Catenin beta 1. | Bone morphogenetic protein 2. | 0.422 |
CTNNB1 | BMP4 | ENSOGAP00000014470 | ENSOGAP00000020983 | Catenin beta 1. | Bone morphogenetic protein 4 (Predicted). | 0.428 |
CTNNB1 | FGF8 | ENSOGAP00000014470 | ENSOGAP00000017738 | Catenin beta 1. | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.428 |
CTNNB1 | WNT2 | ENSOGAP00000014470 | ENSOGAP00000012163 | Catenin beta 1. | Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). | 0.776 |
CTNNB1 | WNT2B | ENSOGAP00000014470 | ENSOGAP00000012597 | Catenin beta 1. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.729 |
FGF1 | FGF10 | ENSOGAP00000004540 | ENSOGAP00000001025 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.608 |
FGF1 | FGF2 | ENSOGAP00000004540 | ENSOGAP00000021960 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.764 |
FGF1 | FGF8 | ENSOGAP00000004540 | ENSOGAP00000017738 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.629 |
FGF1 | FRS2 | ENSOGAP00000004540 | ENSOGAP00000002060 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Fibroblast growth factor receptor substrate 2. | 0.683 |
FGF10 | BMP4 | ENSOGAP00000001025 | ENSOGAP00000020983 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Bone morphogenetic protein 4 (Predicted). | 0.497 |
FGF10 | FGF1 | ENSOGAP00000001025 | ENSOGAP00000004540 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | 0.608 |