STRINGSTRING
MDK MDK ADAMTS15 ADAMTS15 ADAMTS8 ADAMTS8 COL11A1 COL11A1 H0WJU6_OTOGA H0WJU6_OTOGA LGR6 LGR6 AAMP AAMP NDNF NDNF ABI3BP ABI3BP PTPRF PTPRF FGF10 FGF10 LRTM2 LRTM2 CLEC3B CLEC3B LRTM1 LRTM1 TMEM184B TMEM184B ELSPBP1 ELSPBP1 SERPIND1 SERPIND1 LPL LPL H0WG79_OTOGA H0WG79_OTOGA ADAMTSL5 ADAMTSL5 ANOS1 ANOS1 FBLN7 FBLN7 MPO MPO LTBP2 LTBP2 PTCH1 PTCH1 HBEGF HBEGF PTPRS PTPRS PCSK6 PCSK6 APLP1 APLP1 H0WPH9_OTOGA H0WPH9_OTOGA COL13A1 COL13A1 F2 F2 FSTL1 FSTL1 AZU1 AZU1 COMP COMP FN1 FN1 FGF1 FGF1 SERPINC1 SERPINC1 RTN4RL1 RTN4RL1 FURIN FURIN LIPI LIPI CRISPLD1 CRISPLD1 SLIT3 SLIT3 COL25A1 COL25A1 FGFBP1 FGFBP1 VEGFB VEGFB LRRC3B LRRC3B LRPAP1 LRPAP1 CCN3 CCN3 SOST SOST AOC1 AOC1 CTSG CTSG RSPO1 RSPO1 THBS1 THBS1 H0WZE9_OTOGA H0WZE9_OTOGA CDON CDON APLP2 APLP2 HSD17B12 HSD17B12 EVA1C EVA1C ANGPTL3 ANGPTL3 CRISPLD2 CRISPLD2 THBS3 THBS3 FBN1 FBN1 H0X0Z2_OTOGA H0X0Z2_OTOGA SLIT1 SLIT1 SMOC2 SMOC2 FGF12 FGF12 SELP SELP NRP1 NRP1 MPIG6B MPIG6B PLA2G2D PLA2G2D IMPG1 IMPG1 HRG HRG KNG1 KNG1 SMOC1 SMOC1 CCN1 CCN1 PTN PTN LOC105886738 LOC105886738 FGFR4 FGFR4 FGF14 FGF14 FGF4 FGF4 BOC BOC FGFR2 FGFR2 SERPINA5 SERPINA5 CCN5 CCN5 SLIT2 SLIT2 TENM1 TENM1 ADAMTS5 ADAMTS5 MSTN MSTN PCOLCE2 PCOLCE2 LAMC2 LAMC2 FGF7 FGF7 POSTN POSTN NELL1 NELL1 APOH APOH LRRC3 LRRC3 COLQ COLQ CCDC80 CCDC80 ADAMTS3 ADAMTS3 ALK ALK RSPO3 RSPO3 BMP7 BMP7 FGFR1 FGFR1 H0XBV9_OTOGA H0XBV9_OTOGA RPL22 RPL22 ADA2 ADA2 ECM2 ECM2 APOB APOB THBS4 THBS4 SERPINE2 SERPINE2 FGFRL1 FGFRL1 CCN6 CCN6 THBS2 THBS2 APOE APOE ADGRG1 ADGRG1 CCN4 CCN4 COL5A3 COL5A3 LTF LTF PTPRC PTPRC TGFBR3 TGFBR3 EFEMP2 EFEMP2 LIPG LIPG COL23A1 COL23A1 MFGE8 MFGE8 GPNMB GPNMB LOC100942919 LOC100942919 ANG ANG LIPH LIPH CEL CEL TWSG1 TWSG1 ELANE ELANE FGFBP3 FGFBP3 APOA5 APOA5 ADAMTS1 ADAMTS1 HDGFL1 HDGFL1 LIPC LIPC COL5A1 COL5A1 RTN4R RTN4R H0XSV8_OTOGA H0XSV8_OTOGA RSPO2 RSPO2 SFRP1 SFRP1 PRSS57 PRSS57 PRELP PRELP CCN2 CCN2 TMEM184A TMEM184A RSPO4 RSPO4 BMP4 BMP4 IMPG2 IMPG2 CXCL8 CXCL8 FGF9 FGF9 LOC100943374 LOC100943374 GREM2 GREM2 FGF2 FGF2 CXCL10 CXCL10 H0Y1M6_OTOGA H0Y1M6_OTOGA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MDKMidkine. (143 aa)
ADAMTS15ADAM metallopeptidase with thrombospondin type 1 motif 15. (950 aa)
ADAMTS8ADAM metallopeptidase with thrombospondin type 1 motif 8. (905 aa)
COL11A1Collagen type XI alpha 1 chain. (1811 aa)
H0WJU6_OTOGAUncharacterized protein. (1233 aa)
LGR6Leucine rich repeat containing G protein-coupled receptor 6. (965 aa)
AAMPAngio associated migratory cell protein. (436 aa)
NDNFNeuron derived neurotrophic factor. (568 aa)
ABI3BPABI family member 3 binding protein. (1154 aa)
PTPRFProtein tyrosine phosphatase receptor type F. (1793 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LRTM2Leucine rich repeats and transmembrane domains 2. (370 aa)
CLEC3BC-type lectin domain family 3 member B. (202 aa)
LRTM1Leucine rich repeats and transmembrane domains 1. (343 aa)
TMEM184BTransmembrane protein 184B. (414 aa)
ELSPBP1Epididymal sperm binding protein 1. (197 aa)
SERPIND1Serpin family D member 1; Belongs to the serpin family. (501 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (478 aa)
H0WG79_OTOGAPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (232 aa)
ADAMTSL5ADAMTS like 5. (449 aa)
ANOS1Anosmin 1. (596 aa)
FBLN7Fibulin 7. (337 aa)
MPOMyeloperoxidase. (720 aa)
LTBP2Latent transforming growth factor beta binding protein 2. (1815 aa)
PTCH1Patched 1. (1447 aa)
HBEGFHeparin binding EGF like growth factor. (206 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1910 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (865 aa)
APLP1Amyloid beta precursor like protein 1. (643 aa)
H0WPH9_OTOGAUncharacterized protein. (271 aa)
COL13A1Collagen type XIII alpha 1 chain. (682 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
FSTL1Follistatin like 1. (309 aa)
AZU1Azurocidin 1. (250 aa)
COMPCartilage oligomeric matrix protein. (756 aa)
FN1Fibronectin 1. (1987 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
SERPINC1Serpin family C member 1; Belongs to the serpin family. (465 aa)
RTN4RL1Reticulon 4 receptor like 1. (444 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (793 aa)
LIPILipase I. (446 aa)
CRISPLD1Cysteine rich secretory protein LCCL domain containing 1. (500 aa)
SLIT3Slit guidance ligand 3. (1337 aa)
COL25A1Collagen type XXV alpha 1 chain. (498 aa)
FGFBP1Fibroblast growth factor binding protein 1. (235 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa)
LRRC3BLeucine rich repeat containing 3B. (259 aa)
LRPAP1LDL receptor related protein associated protein 1. (362 aa)
CCN3Cellular communication network factor 3. (351 aa)
SOSTSclerostin. (213 aa)
AOC1Amine oxidase. (757 aa)
CTSGCathepsin G; Belongs to the peptidase S1 family. (253 aa)
RSPO1R-spondin 1. (263 aa)
THBS1Thrombospondin 1. (1170 aa)
H0WZE9_OTOGACarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (599 aa)
CDONCell adhesion associated, oncogene regulated. (1247 aa)
APLP2Amyloid beta precursor like protein 2. (684 aa)
HSD17B12Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (219 aa)
EVA1CEva-1 homolog C. (441 aa)
ANGPTL3Angiopoietin like 3. (460 aa)
CRISPLD2Cysteine rich secretory protein LCCL domain containing 2. (496 aa)
THBS3Thrombospondin 3. (956 aa)
FBN1Fibrillin 1. (2875 aa)
H0X0Z2_OTOGAUncharacterized protein. (4063 aa)
SLIT1Slit guidance ligand 1. (1427 aa)
SMOC2SPARC related modular calcium binding 2. (446 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
SELPSelectin P. (769 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (926 aa)
MPIG6BMegakaryocyte and platelet inhibitory receptor G6b. (241 aa)
PLA2G2DPhospholipase A(2). (145 aa)
IMPG1Interphotoreceptor matrix proteoglycan 1. (795 aa)
HRGCystatin domain-containing protein. (429 aa)
KNG1Kininogen 1. (646 aa)
SMOC1SPARC related modular calcium binding 1. (435 aa)
CCN1Cellular communication network factor 1. (383 aa)
PTNPleiotrophin. (168 aa)
LOC105886738Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (120 aa)
FGFR4Fibroblast growth factor receptor 4. (969 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (247 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
BOCBOC cell adhesion associated, oncogene regulated. (974 aa)
FGFR2Fibroblast growth factor receptor. (822 aa)
SERPINA5Serpin family A member 5; Belongs to the serpin family. (408 aa)
CCN5Cellular communication network factor 5. (250 aa)
SLIT2Slit guidance ligand 2. (1411 aa)
TENM1Teneurin transmembrane protein 1. (2569 aa)
ADAMTS5ADAM metallopeptidase with thrombospondin type 1 motif 5. (930 aa)
MSTNMyostatin. (375 aa)
PCOLCE2Procollagen C-endopeptidase enhancer 2. (415 aa)
LAMC2Laminin subunit gamma 2. (1188 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
POSTNPeriostin. (798 aa)
NELL1Neural EGFL like 1. (808 aa)
APOHApolipoprotein H. (345 aa)
LRRC3Leucine rich repeat containing 3. (254 aa)
COLQCollagen like tail subunit of asymmetric acetylcholinesterase. (451 aa)
CCDC80Coiled-coil domain containing 80. (952 aa)
ADAMTS3ADAM metallopeptidase with thrombospondin type 1 motif 3. (888 aa)
ALKTyrosine-protein kinase receptor. (1200 aa)
RSPO3R-spondin 3. (211 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
FGFR1Fibroblast growth factor receptor. (792 aa)
H0XBV9_OTOGAC-type lectin domain-containing protein. (227 aa)
RPL22Ribosomal protein L22. (128 aa)
ADA2Adenosine deaminase 2. (513 aa)
ECM2Extracellular matrix protein 2. (676 aa)
APOBApolipoprotein B. (4544 aa)
THBS4Thrombospondin 4. (961 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (397 aa)
FGFRL1Fibroblast growth factor receptor like 1. (497 aa)
CCN6Cellular communication network factor 6. (353 aa)
THBS2Thrombospondin 2. (1172 aa)
APOEApolipoprotein E. (314 aa)
ADGRG1Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (686 aa)
CCN4Cellular communication network factor 4. (367 aa)
COL5A3Collagen type V alpha 3 chain. (1749 aa)
LTFLactotransferrin; Belongs to the transferrin family. (710 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1299 aa)
TGFBR3Transforming growth factor beta receptor 3. (852 aa)
EFEMP2EGF containing fibulin extracellular matrix protein 2. (443 aa)
LIPGLipase G, endothelial type. (503 aa)
COL23A1Collagen type XXIII alpha 1 chain. (398 aa)
MFGE8Milk fat globule-EGF factor 8 protein. (430 aa)
GPNMBGlycoprotein nmb. (590 aa)
LOC100942919Uncharacterized protein. (222 aa)
ANGAngiogenin; Belongs to the pancreatic ribonuclease family. (146 aa)
LIPHLipase H. (448 aa)
CELCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (601 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (182 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (265 aa)
FGFBP3Fibroblast growth factor binding protein 3. (247 aa)
APOA5Apolipoprotein A5. (368 aa)
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif 1. (945 aa)
HDGFL1HDGF like 1. (236 aa)
LIPCLipase C, hepatic type. (477 aa)
COL5A1Collagen type V alpha 1 chain. (1843 aa)
RTN4RReticulon 4 receptor. (473 aa)
H0XSV8_OTOGAUncharacterized protein. (293 aa)
RSPO2R-spondin 2. (204 aa)
SFRP1Secreted frizzled related protein 1. (318 aa)
PRSS57Serine protease 57. (268 aa)
PRELPProline and arginine rich end leucine rich repeat protein. (370 aa)
CCN2Cellular communication network factor 2. (349 aa)
TMEM184ATransmembrane protein 184A. (423 aa)
RSPO4R-spondin 4. (202 aa)
BMP4Bone morphogenetic protein 4 (Predicted). (409 aa)
IMPG2Interphotoreceptor matrix proteoglycan 2. (1237 aa)
CXCL8Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (99 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LOC100943374Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (122 aa)
GREM2Gremlin. (168 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
CXCL10C-X-C motif chemokine. (98 aa)
H0Y1M6_OTOGAUncharacterized protein. (130 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
Server load: low (26%) [HD]