STRINGSTRING
AP1G1 AP1G1 AP4M1 AP4M1 SGIP1 SGIP1 AP1G2 AP1G2 AP2A2 AP2A2 AP1B1 AP1B1 AP4B1 AP4B1 AFTPH AFTPH AP1S2 AP1S2 AP1M2 AP1M2 LOC100950940 LOC100950940 H0XQI6_OTOGA H0XQI6_OTOGA AP2M1 AP2M1 SLC18A3 SLC18A3 AP3M1 AP3M1 AP2A1 AP2A1 AP1M1 AP1M1 AP1S3 AP1S3 AP3M2 AP3M2 AP2S1 AP2S1 SYNRG SYNRG AP2B1 AP2B1 AP1S1 AP1S1 AP3B1 AP3B1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AP1G1AP-1 complex subunit gamma. (823 aa)
AP4M1AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (453 aa)
SGIP1SH3 domain GRB2 like endophilin interacting protein 1; Belongs to the adaptor complexes medium subunit family. (500 aa)
AP1G2AP-1 complex subunit gamma. (785 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (930 aa)
AP1B1AP complex subunit beta. (947 aa)
AP4B1AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (739 aa)
AFTPHAftiphilin. (909 aa)
AP1S2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
AP1M2AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (423 aa)
LOC100950940Clathrin_bdg domain-containing protein. (906 aa)
H0XQI6_OTOGAAP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (437 aa)
SLC18A3Solute carrier family 18 member A3. (532 aa)
AP3M1AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family. (418 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (946 aa)
AP1M1AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (423 aa)
AP1S3AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa)
AP3M2AP-3 complex subunit mu-2. (418 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
SYNRGSynergin gamma. (862 aa)
AP2B1Adaptor related protein complex 2 subunit beta 1. (951 aa)
AP1S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (177 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1083 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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