STRINGSTRING
LSM6-2 LSM6-2 C19orf54 C19orf54 H0XJX1_OTOGA H0XJX1_OTOGA LSM6 LSM6 LSM4 LSM4 MEPCE MEPCE DDX23 DDX23 FMC1-LUC7L2 FMC1-LUC7L2 CD2BP2 CD2BP2 SART1 SART1 SNRPB SNRPB SNRPG SNRPG SNRPB2 SNRPB2 PPIH PPIH PRPF40A PRPF40A H0XAZ5_OTOGA H0XAZ5_OTOGA LSM5 LSM5 LSM8 LSM8 SF3A1 SF3A1 EFTUD2 EFTUD2 H0X7Q6_OTOGA H0X7Q6_OTOGA TGS1 TGS1 SLU7 SLU7 USP39 USP39 SF3B5 SF3B5 SF3A3 SF3A3 BUD13 BUD13 H0X0J6_OTOGA H0X0J6_OTOGA LSM11 LSM11 TXNL4B TXNL4B SNIP1 SNIP1 H0WYE9_OTOGA H0WYE9_OTOGA SNRPD1 SNRPD1 PRPF4 PRPF4 LSM3 LSM3 PRPF31 PRPF31 SNRNP200 SNRNP200 SF3B4 SF3B4 ARFGEF1 ARFGEF1 H0WTS0_OTOGA H0WTS0_OTOGA SF3B2 SF3B2 PRPF3 PRPF3 SF3A2 SF3A2 H0XSR3_OTOGA H0XSR3_OTOGA H0XSL2_OTOGA H0XSL2_OTOGA LOC100957263 LOC100957263 H0WLK5_OTOGA H0WLK5_OTOGA LSM3-2 LSM3-2 H0XMN3_OTOGA H0XMN3_OTOGA PRPF40B PRPF40B SNRNP40 SNRNP40 LUC7L3 LUC7L3 SF3B6 SF3B6 SNRPE SNRPE RBM42 RBM42 SNU13 SNU13 SNRPA SNRPA LSM10 LSM10 H0WFU3_OTOGA H0WFU3_OTOGA H0WG26_OTOGA H0WG26_OTOGA LARP7 LARP7 ZMAT2 ZMAT2 H0XTQ5_OTOGA H0XTQ5_OTOGA SNRNP70 SNRNP70 SNRPD3 SNRPD3 H0XW89_OTOGA H0XW89_OTOGA SNRPD2 SNRPD2 GEMIN4 GEMIN4 TXNL4A TXNL4A H0XX70_OTOGA H0XX70_OTOGA SNRPC SNRPC SNRPC-2 SNRPC-2 LSM3-3 LSM3-3 PRPF39 PRPF39 SNRPC-3 SNRPC-3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LSM6-2LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (80 aa)
C19orf54Chromosome 19 open reading frame 54. (337 aa)
H0XJX1_OTOGARRM domain-containing protein. (159 aa)
LSM6Sm domain-containing protein. (80 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (146 aa)
MEPCEMethylphosphate capping enzyme. (676 aa)
DDX23DEAD-box helicase 23. (820 aa)
FMC1-LUC7L2FMC1-LUC7L2 readthrough. (458 aa)
CD2BP2CD2 cytoplasmic tail binding protein 2. (340 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (801 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (240 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (73 aa)
SNRPB2Small nuclear ribonucleoprotein polypeptide B2. (225 aa)
PPIHPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (177 aa)
PRPF40APre-mRNA processing factor 40 homolog A. (938 aa)
H0XAZ5_OTOGASm domain-containing protein. (53 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
LSM8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
SF3A1Splicing factor 3a subunit 1. (793 aa)
EFTUD2Elongation factor Tu GTP binding domain containing 2. (969 aa)
H0X7Q6_OTOGAU6-snRNA_bdg domain-containing protein. (129 aa)
TGS1Trimethylguanosine synthase 1. (853 aa)
SLU7SLU7 homolog, splicing factor. (586 aa)
USP39Ubiquitin specific peptidase 39. (488 aa)
SF3B5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
SF3A3Splicing factor 3a subunit 3. (401 aa)
BUD13BUD13 homolog. (616 aa)
H0X0J6_OTOGAUncharacterized protein. (191 aa)
LSM11LSM11, U7 small nuclear RNA associated. (211 aa)
TXNL4BThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (149 aa)
SNIP1Smad nuclear interacting protein 1. (390 aa)
H0WYE9_OTOGASNRNP27 domain-containing protein. (157 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
PRPF4Pre-mRNA processing factor 4. (533 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
PRPF31PRP31 pre-mRNA processing factor 31 homolog (Predicted). (307 aa)
SNRNP200Small nuclear ribonucleoprotein U5 subunit 200. (2136 aa)
SF3B4Splicing factor 3b subunit 4. (424 aa)
ARFGEF1ADP ribosylation factor guanine nucleotide exchange factor 1. (1849 aa)
H0WTS0_OTOGARRM domain-containing protein. (326 aa)
SF3B2Splicing factor 3b subunit 2. (893 aa)
PRPF3Pre-mRNA processing factor 3. (682 aa)
SF3A2Splicing factor 3a subunit 2. (464 aa)
H0XSR3_OTOGAUncharacterized protein. (429 aa)
H0XSL2_OTOGASm domain-containing protein. (102 aa)
LOC100957263Sm domain-containing protein. (86 aa)
H0WLK5_OTOGAUncharacterized protein. (102 aa)
LSM3-2U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (98 aa)
H0XMN3_OTOGAWD_REPEATS_REGION domain-containing protein. (331 aa)
PRPF40BPre-mRNA processing factor 40 homolog B. (873 aa)
SNRNP40WD_REPEATS_REGION domain-containing protein. (358 aa)
LUC7L3LUC7 like 3 pre-mRNA splicing factor. (434 aa)
SF3B6Splicing factor 3b subunit 6. (125 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (76 aa)
RBM42RNA binding motif protein 42. (477 aa)
SNU13Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (127 aa)
SNRPASmall nuclear ribonucleoprotein polypeptide A. (282 aa)
LSM10LSM10, U7 small nuclear RNA associated. (123 aa)
H0WFU3_OTOGASm domain-containing protein. (102 aa)
H0WG26_OTOGASF3b1 domain-containing protein. (627 aa)
LARP7La ribonucleoprotein domain family member 7. (584 aa)
ZMAT2Zinc finger matrin-type 2. (199 aa)
H0XTQ5_OTOGAUncharacterized protein. (110 aa)
SNRNP70Small nuclear ribonucleoprotein U1 subunit 70. (440 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (148 aa)
H0XW89_OTOGAUncharacterized protein. (360 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (117 aa)
GEMIN4Gem nuclear organelle associated protein 4. (1057 aa)
TXNL4AThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
H0XX70_OTOGAUncharacterized protein. (104 aa)
SNRPCU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (152 aa)
SNRPC-2U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (178 aa)
LSM3-3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (100 aa)
PRPF39Pre-mRNA processing factor 39. (669 aa)
SNRPC-3U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (159 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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