16 items (Otolemur garnettii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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Your Input:
	SHANK2	SH3 and multiple ankyrin repeat domains 2. (1170 aa)
	RAPSN	Receptor associated protein of the synapse. (404 aa)
	CDK5R1	Cyclin-dependent kinase 5 activator. (306 aa)
	H0XT55_OTOGA	Uncharacterized protein. (285 aa)
	GNAS	GNAS complex locus. (1146 aa)
	SHANK1	SH3 and multiple ankyrin repeat domains 1. (2174 aa)
	SHISA7	Shisa family member 7. (539 aa)
	LOC100966244	Uncharacterized protein. (260 aa)
	SHANK3	SH3 and multiple ankyrin repeat domains 3. (1751 aa)
	FLOT2	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (459 aa)
	IGSF11	Immunoglobulin superfamily member 11. (431 aa)
	CACNG4	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
	NETO1	Neuropilin and tolloid like 1. (533 aa)
	NETO2	Neuropilin and tolloid like 2. (498 aa)
	DLG4	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (808 aa)
	CACNG2	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CACNG2	CACNG4	ENSOGAP00000002669	ENSOGAP00000012213	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	0.887
CACNG2	DLG4	ENSOGAP00000002669	ENSOGAP00000003912	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.919
CACNG4	CACNG2	ENSOGAP00000012213	ENSOGAP00000002669	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	0.887
CACNG4	DLG4	ENSOGAP00000012213	ENSOGAP00000003912	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.780
DLG4	CACNG2	ENSOGAP00000003912	ENSOGAP00000002669	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	0.919
DLG4	CACNG4	ENSOGAP00000003912	ENSOGAP00000012213	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	0.780
DLG4	SHANK1	ENSOGAP00000003912	ENSOGAP00000017779	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains 1.	0.909
DLG4	SHANK2	ENSOGAP00000003912	ENSOGAP00000016952	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains 2.	0.891
DLG4	SHANK3	ENSOGAP00000003912	ENSOGAP00000016208	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains 3.	0.886
GNAS	LOC100966244	ENSOGAP00000018337	ENSOGAP00000016281	GNAS complex locus.	Uncharacterized protein.	0.852
LOC100966244	GNAS	ENSOGAP00000016281	ENSOGAP00000018337	Uncharacterized protein.	GNAS complex locus.	0.852
SHANK1	DLG4	ENSOGAP00000017779	ENSOGAP00000003912	SH3 and multiple ankyrin repeat domains 1.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.909
SHANK1	SHANK2	ENSOGAP00000017779	ENSOGAP00000016952	SH3 and multiple ankyrin repeat domains 1.	SH3 and multiple ankyrin repeat domains 2.	0.895
SHANK1	SHANK3	ENSOGAP00000017779	ENSOGAP00000016208	SH3 and multiple ankyrin repeat domains 1.	SH3 and multiple ankyrin repeat domains 3.	0.960
SHANK1	SHISA7	ENSOGAP00000017779	ENSOGAP00000016349	SH3 and multiple ankyrin repeat domains 1.	Shisa family member 7.	0.438
SHANK2	DLG4	ENSOGAP00000016952	ENSOGAP00000003912	SH3 and multiple ankyrin repeat domains 2.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.891
SHANK2	SHANK1	ENSOGAP00000016952	ENSOGAP00000017779	SH3 and multiple ankyrin repeat domains 2.	SH3 and multiple ankyrin repeat domains 1.	0.895
SHANK2	SHANK3	ENSOGAP00000016952	ENSOGAP00000016208	SH3 and multiple ankyrin repeat domains 2.	SH3 and multiple ankyrin repeat domains 3.	0.915
SHANK3	DLG4	ENSOGAP00000016208	ENSOGAP00000003912	SH3 and multiple ankyrin repeat domains 3.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.886
SHANK3	SHANK1	ENSOGAP00000016208	ENSOGAP00000017779	SH3 and multiple ankyrin repeat domains 3.	SH3 and multiple ankyrin repeat domains 1.	0.960