17 items (Otolemur garnettii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	H0X5G6_OTOGA	Stonin-1; May be involved in the endocytic machinery. (1179 aa)
	AP1S3	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa)
	DAB2	DAB adaptor protein 2. (768 aa)
	AP1M1	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (423 aa)
	AP2A1	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (946 aa)
	H0XQI6_OTOGA	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa)
	AP2S1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	AP1S1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (177 aa)
	HIP1	Huntingtin interacting protein 1. (951 aa)
	AP2A2	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (930 aa)
	LDLRAP1	Low density lipoprotein receptor adaptor protein 1. (308 aa)
	AP1G1	AP-1 complex subunit gamma. (823 aa)
	STON2	Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family. (927 aa)
	AP1G2	AP-1 complex subunit gamma. (785 aa)
	AP1S2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
	AP1M2	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (423 aa)
	HIP1R	Huntingtin interacting protein 1 related. (1080 aa)

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP1G1	AP1G2	ENSOGAP00000002563	ENSOGAP00000007837	AP-1 complex subunit gamma.	AP-1 complex subunit gamma.	0.889
AP1G1	AP1M1	ENSOGAP00000002563	ENSOGAP00000014367	AP-1 complex subunit gamma.	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.986
AP1G1	AP1M2	ENSOGAP00000002563	ENSOGAP00000012928	AP-1 complex subunit gamma.	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.986
AP1G1	AP1S1	ENSOGAP00000002563	ENSOGAP00000000682	AP-1 complex subunit gamma.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.991
AP1G1	AP1S2	ENSOGAP00000002563	ENSOGAP00000010160	AP-1 complex subunit gamma.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.974
AP1G1	AP1S3	ENSOGAP00000002563	ENSOGAP00000013621	AP-1 complex subunit gamma.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.991
AP1G1	AP2A1	ENSOGAP00000002563	ENSOGAP00000014774	AP-1 complex subunit gamma.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.494
AP1G1	AP2A2	ENSOGAP00000002563	ENSOGAP00000001697	AP-1 complex subunit gamma.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.498
AP1G1	AP2S1	ENSOGAP00000002563	ENSOGAP00000020789	AP-1 complex subunit gamma.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.949
AP1G1	DAB2	ENSOGAP00000002563	ENSOGAP00000014097	AP-1 complex subunit gamma.	DAB adaptor protein 2.	0.410
AP1G1	H0X5G6_OTOGA	ENSOGAP00000002563	ENSOGAP00000010519	AP-1 complex subunit gamma.	Stonin-1; May be involved in the endocytic machinery.	0.494
AP1G1	H0XQI6_OTOGA	ENSOGAP00000002563	ENSOGAP00000018378	AP-1 complex subunit gamma.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.974
AP1G1	HIP1	ENSOGAP00000002563	ENSOGAP00000001233	AP-1 complex subunit gamma.	Huntingtin interacting protein 1.	0.654
AP1G1	HIP1R	ENSOGAP00000002563	ENSOGAP00000012280	AP-1 complex subunit gamma.	Huntingtin interacting protein 1 related.	0.654
AP1G1	STON2	ENSOGAP00000002563	ENSOGAP00000004678	AP-1 complex subunit gamma.	Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family.	0.488
AP1G2	AP1G1	ENSOGAP00000007837	ENSOGAP00000002563	AP-1 complex subunit gamma.	AP-1 complex subunit gamma.	0.889
AP1G2	AP1M1	ENSOGAP00000007837	ENSOGAP00000014367	AP-1 complex subunit gamma.	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.979
AP1G2	AP1M2	ENSOGAP00000007837	ENSOGAP00000012928	AP-1 complex subunit gamma.	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.979
AP1G2	AP1S1	ENSOGAP00000007837	ENSOGAP00000000682	AP-1 complex subunit gamma.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.991
AP1G2	AP1S2	ENSOGAP00000007837	ENSOGAP00000010160	AP-1 complex subunit gamma.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.973