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GRIK2 GRIK2 GABBR1 GABBR1 ATP2B4 ATP2B4 GABRA5 GABRA5 KCNC2 KCNC2 PCDH8 PCDH8 SLC6A9 SLC6A9 HIP1 HIP1 CNTN1 CNTN1 EFNB3 EFNB3 ADCY8 ADCY8 STX3 STX3 NCSTN NCSTN GRIK4 GRIK4 KCTD16 KCTD16 SCN2A SCN2A SYT11 SYT11 CNTN6 CNTN6 RIMS1 RIMS1 IGSF21 IGSF21 DNM1 DNM1 SYP SYP PTPRS PTPRS EFNB2 EFNB2 PSENEN PSENEN SLC6A2 SLC6A2 CNTN5 CNTN5 H0WQJ9_OTOGA H0WQJ9_OTOGA APH1A APH1A CASK CASK ADGRL1 ADGRL1 CADM3 CADM3 SLC4A8 SLC4A8 KCNJ3 KCNJ3 SNAP25 SNAP25 UNC13C UNC13C RIMS3 RIMS3 PDE2A PDE2A NRXN1 NRXN1 DRD2 DRD2 GRM3 GRM3 OTOF OTOF APBA1 APBA1 SNCAIP SNCAIP RGS7BP RGS7BP NECTIN1 NECTIN1 ERC2 ERC2 PTPRD PTPRD EXOC3 EXOC3 ATP2B1 ATP2B1 CDH10 CDH10 P2RX1 P2RX1 ATP2B3 ATP2B3 CNTNAP1 CNTNAP1 PI4K2A PI4K2A H0X324_OTOGA H0X324_OTOGA H0X3E3_OTOGA H0X3E3_OTOGA GAD2 GAD2 KCNC1 KCNC1 STX2 STX2 NLGN2 NLGN2 NRG1 NRG1 KCTD8 KCTD8 GPER1 GPER1 SNAP91 SNAP91 GRM2 GRM2 UNC13B UNC13B SLC6A1 SLC6A1 FMR1 FMR1 SLC1A7 SLC1A7 SLC6A5 SLC6A5 DENND1A DENND1A PICALM PICALM ZDHHC17 ZDHHC17 RIMS2 RIMS2 STX1B STX1B STX4 STX4 SCN10A SCN10A EPHB2 EPHB2 P2RX3 P2RX3 ERC1 ERC1 PICK1 PICK1 FXYD6 FXYD6 GRIK5 GRIK5 CTNNB1 CTNNB1 NTNG1 NTNG1 SLC1A2 SLC1A2 FOSL1 FOSL1 ATP2B2 ATP2B2 ADRA1A ADRA1A STX1A STX1A H0XJR5_OTOGA H0XJR5_OTOGA H0XK42_OTOGA H0XK42_OTOGA NPTN NPTN FBXO45 FBXO45 UNC13A UNC13A CLTA CLTA KCNC3 KCNC3 KCTD12 KCTD12 PCDH17 PCDH17 H0XPN8_OTOGA H0XPN8_OTOGA SYT7 SYT7 SYAP1 SYAP1 KCNJ9 KCNJ9 LRFN3 LRFN3 H0XUL4_OTOGA H0XUL4_OTOGA CHRNB2 CHRNB2 STX11 STX11 ADORA2A ADORA2A CLTB CLTB SLC1A6 SLC1A6 NTNG2 NTNG2 H0XXJ6_OTOGA H0XXJ6_OTOGA OPRD1 OPRD1 CPLX3 CPLX3 P2RY1 P2RY1 P2RY4 P2RY4 H0Y0Y0_OTOGA H0Y0Y0_OTOGA PRRT2 PRRT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (912 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (961 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1203 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (640 aa)
PCDH8Protocadherin 8. (668 aa)
SLC6A9Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (706 aa)
HIP1Huntingtin interacting protein 1. (951 aa)
CNTN1Contactin 1. (1021 aa)
EFNB3Ephrin B3; Belongs to the ephrin family. (340 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1120 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (287 aa)
NCSTNNicastrin. (709 aa)
GRIK4Glutamate ionotropic receptor kainate type subunit 4. (940 aa)
KCTD16Potassium channel tetramerization domain containing 16. (428 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1991 aa)
SYT11Synaptotagmin 11. (437 aa)
CNTN6Contactin 6. (1030 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1016 aa)
IGSF21Immunoglobin superfamily member 21. (374 aa)
DNM1Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (851 aa)
SYPSynaptophysin. (313 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1910 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (335 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
SLC6A2Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (617 aa)
CNTN5Contactin 5. (1083 aa)
H0WQJ9_OTOGASodium/potassium-transporting ATPase subunit alpha. (1022 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (926 aa)
ADGRL1Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family. (1529 aa)
CADM3Cell adhesion molecule 3. (395 aa)
SLC4A8Anion exchange protein. (1104 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
UNC13CUnc-13 homolog C. (2216 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (309 aa)
PDE2APhosphodiesterase. (895 aa)
NRXN1Neurexin 1. (853 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
GRM3Glutamate metabotropic receptor 3. (879 aa)
OTOFOtoferlin. (1925 aa)
APBA1Amyloid beta precursor protein binding family A member 1. (839 aa)
SNCAIPSynuclein alpha interacting protein. (962 aa)
RGS7BPRegulator of G protein signaling 7 binding protein. (257 aa)
NECTIN1Nectin cell adhesion molecule 1. (512 aa)
ERC2ELKS/RAB6-interacting/CAST family member 2. (958 aa)
PTPRDProtein tyrosine phosphatase receptor type D. (1798 aa)
EXOC3Exocyst complex component 3. (745 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1259 aa)
CDH10Cadherin 10; Cadherins are calcium-dependent cell adhesion proteins. (788 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa)
CNTNAP1Contactin associated protein 1. (1384 aa)
PI4K2APhosphatidylinositol 4-kinase type 2 alpha. (479 aa)
H0X324_OTOGANMDAR2_C domain-containing protein. (426 aa)
H0X3E3_OTOGAProtein kinase domain-containing protein. (690 aa)
GAD2Glutamate decarboxylase 2. (585 aa)
KCNC1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (585 aa)
STX2t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (288 aa)
NLGN2Neuroligin 2. (822 aa)
NRG1Neuregulin 1. (510 aa)
KCTD8Potassium channel tetramerization domain containing 8. (302 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (374 aa)
SNAP91Synaptosome associated protein 91. (877 aa)
GRM2Glutamate metabotropic receptor 2. (872 aa)
UNC13BUnc-13 homolog B. (1734 aa)
SLC6A1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (602 aa)
FMR1Fragile X mental retardation 1. (632 aa)
SLC1A7Amino acid transporter. (574 aa)
SLC6A5Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (797 aa)
DENND1ADENN domain containing 1A. (1024 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (722 aa)
ZDHHC17Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (624 aa)
RIMS2Regulating synaptic membrane exocytosis 2. (1381 aa)
STX1BSyntaxin 1B; Belongs to the syntaxin family. (288 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (298 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1958 aa)
EPHB2EPH receptor B2. (1040 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (395 aa)
ERC1ELKS/RAB6-interacting/CAST family member 1. (874 aa)
PICK1Protein interacting with PRKCA 1. (417 aa)
FXYD6FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (102 aa)
GRIK5Glutamate ionotropic receptor kainate type subunit 5. (977 aa)
CTNNB1Catenin beta 1. (781 aa)
NTNG1Netrin G1. (531 aa)
SLC1A2Amino acid transporter. (576 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (272 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1198 aa)
ADRA1AAdrenoceptor alpha 1A. (468 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (326 aa)
H0XJR5_OTOGAUncharacterized protein. (115 aa)
H0XK42_OTOGAProtein kinase domain-containing protein. (482 aa)
NPTNNeuroplastin. (400 aa)
FBXO45F-box protein 45. (292 aa)
UNC13AUnc-13 homolog A. (1759 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (217 aa)
KCNC3Potassium voltage-gated channel subfamily C member 3; Belongs to the potassium channel family. (773 aa)
KCTD12Potassium channel tetramerization domain containing 12. (328 aa)
PCDH17Protocadherin 17. (1159 aa)
H0XPN8_OTOGAt-SNARE coiled-coil homology domain-containing protein. (284 aa)
SYT7Synaptotagmin 7. (684 aa)
SYAP1Synapse associated protein 1. (358 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (393 aa)
LRFN3Leucine rich repeat and fibronectin type III domain containing 3. (623 aa)
H0XUL4_OTOGAt-SNARE coiled-coil homology domain-containing protein. (275 aa)
CHRNB2Cholinergic receptor nicotinic beta 2 subunit. (502 aa)
STX11Syntaxin 11; Belongs to the syntaxin family. (287 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (263 aa)
SLC1A6Amino acid transporter. (566 aa)
NTNG2Netrin G2. (533 aa)
H0XXJ6_OTOGAENTH domain-containing protein. (239 aa)
OPRD1Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
CPLX3Complexin 3. (158 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
P2RY4Pyrimidinergic receptor P2Y4; Belongs to the G-protein coupled receptor 1 family. (365 aa)
H0Y0Y0_OTOGAUncharacterized protein. (264 aa)
PRRT2Proline rich transmembrane protein 2. (353 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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