STRINGSTRING
H0XS74_OTOGA H0XS74_OTOGA KCNE2 KCNE2 BNC2 BNC2 TBX1 TBX1 LEF1 LEF1 HDAC1 HDAC1 INTU INTU CYP26B1 CYP26B1 HDAC2 HDAC2 GLI3 GLI3 SIX4 SIX4 CTNNB1 CTNNB1 WNT10B WNT10B WNT10A WNT10A WDPCP WDPCP HOXC13 HOXC13 NKX2-6 NKX2-6 NTF4 NTF4 HAND2 HAND2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H0XS74_OTOGAUncharacterized protein. (132 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
BNC2Basonuclin 2. (879 aa)
TBX1T-box transcription factor 1. (374 aa)
LEF1Lymphoid enhancer binding factor 1. (398 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
INTUInturned planar cell polarity protein. (938 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (513 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (422 aa)
GLI3GLI family zinc finger 3. (1462 aa)
SIX4SIX homeobox 4. (685 aa)
CTNNB1Catenin beta 1. (781 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
WDPCPWD repeat containing planar cell polarity effector. (739 aa)
HOXC13Homeobox C13. (329 aa)
NKX2-6NK2 homeobox 6. (215 aa)
NTF4Neurotrophin 4; Belongs to the NGF-beta family. (210 aa)
HAND2Heart and neural crest derivatives expressed 2. (182 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
Server load: low (16%) [HD]