STRINGSTRING
PPP1R13L PPP1R13L MTOR MTOR TNNI2 TNNI2 SCN4B SCN4B DMD DMD KCNE5 KCNE5 KCNE1 KCNE1 CAV3 CAV3 CACNA1C CACNA1C MYL2 MYL2 GRK2 GRK2 MAP2K6 MAP2K6 TNNC1 TNNC1 MAP2K3 MAP2K3 CACNA1G CACNA1G SLC8A1 SLC8A1 KCNJ3 KCNJ3 PKP2 PKP2 CSRP3 CSRP3 H0WSX1_OTOGA H0WSX1_OTOGA CACNA2D1 CACNA2D1 PIK3CA PIK3CA CAMK2D CAMK2D ATP1B1 ATP1B1 FGF12 FGF12 SMAD5 SMAD5 SCN2B SCN2B KCNN2 KCNN2 TNNT2 TNNT2 TAZ TAZ MYL10 MYL10 KCNH2 KCNH2 VEGFB VEGFB KCNE2 KCNE2 KCNJ5 KCNJ5 MYBPC3 MYBPC3 MYLK2 MYLK2 NUP155 NUP155 SCN5A SCN5A KCNQ1 KCNQ1 SLC9A1 SLC9A1 GSN GSN SCN1B SCN1B CACNB2 CACNB2 KCNE3 KCNE3 H0XTM2_OTOGA H0XTM2_OTOGA SNTA1 SNTA1 TCAP TCAP NKX2-5 NKX2-5 GJA1 GJA1 KCNJ8 KCNJ8 RYR2 RYR2 ABCC9 ABCC9 MYL3 MYL3 SCN1A SCN1A KCNE4 KCNE4 TNNI3 TNNI3 MYL4 MYL4 TNNI1 TNNI1 CASQ2 CASQ2 SGCD SGCD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP1R13LProtein phosphatase 1 regulatory subunit 13 like. (829 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
TNNI2Troponin I2, fast skeletal type. (182 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (227 aa)
DMDDystrophin. (3682 aa)
KCNE5Potassium voltage-gated channel subfamily E regulatory subunit 5. (146 aa)
KCNE1Uncharacterized protein. (129 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2005 aa)
MYL2Myosin light chain 2. (166 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (686 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (336 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (161 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (336 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2342 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
PKP2Plakophilin 2. (881 aa)
CSRP3Cysteine and glycine rich protein 3. (194 aa)
H0WSX1_OTOGAUncharacterized protein. (1711 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1074 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (502 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
SCN2BSodium voltage-gated channel beta subunit 2. (215 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (703 aa)
TNNT2Troponin T2, cardiac type. (306 aa)
TAZTafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (290 aa)
MYL10Myosin light chain 10. (202 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1162 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
MYBPC3Myosin binding protein C, cardiac. (1280 aa)
MYLK2Myosin light chain kinase 2. (612 aa)
NUP155Nucleoporin 155. (1426 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2020 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (675 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa)
GSNGelsolin. (783 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (218 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (612 aa)
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (107 aa)
H0XTM2_OTOGAUncharacterized protein. (5585 aa)
SNTA1Syntrophin alpha 1. (509 aa)
TCAPTitin-cap. (167 aa)
NKX2-5NK2 homeobox 5. (324 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
KCNJ8Potassium voltage-gated channel subfamily J member 8. (424 aa)
RYR2Ryanodine receptor 2. (4867 aa)
ABCC9ATP binding cassette subfamily C member 9. (1551 aa)
MYL3Myosin light chain 3. (195 aa)
SCN1ASodium voltage-gated channel alpha subunit 1. (1656 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (169 aa)
TNNI3Troponin I3, cardiac type. (212 aa)
MYL4Myosin light chain 4. (197 aa)
TNNI1Troponin I1, slow skeletal type. (187 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (407 aa)
SGCDSarcoglycan delta. (290 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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