17 items (Otolemur garnettii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SHANK1	SH3 and multiple ankyrin repeat domains 1. (2174 aa)
	CTNND2	Catenin delta 2. (1139 aa)
	DLG4	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (808 aa)
	EPHB3	EPH receptor B3. (1004 aa)
	WNT7B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	WNT7A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
	SHANK3	SH3 and multiple ankyrin repeat domains 3. (1751 aa)
	PAK3	Non-specific serine/threonine protein kinase. (559 aa)
	EPHB2	EPH receptor B2. (1040 aa)
	CDC42	Uncharacterized protein. (191 aa)
	H0XQZ6_OTOGA	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (369 aa)
	HDAC6	Histone deacetylase 6. (1210 aa)
	EPHB1	EPH receptor B1. (962 aa)
	DIP2A	Disco interacting protein 2 homolog A. (1578 aa)
	PRMT3	Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (530 aa)
	WASL	WASP like actin nucleation promoting factor. (509 aa)
	DOCK10	Dedicator of cytokinesis 10; Belongs to the DOCK family. (2183 aa)

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	CTNND2	ENSOGAP00000012779	ENSOGAP00000004842	Uncharacterized protein.	Catenin delta 2.	0.652
CDC42	DLG4	ENSOGAP00000012779	ENSOGAP00000003912	Uncharacterized protein.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.542
CDC42	DOCK10	ENSOGAP00000012779	ENSOGAP00000005836	Uncharacterized protein.	Dedicator of cytokinesis 10; Belongs to the DOCK family.	0.935
CDC42	EPHB1	ENSOGAP00000012779	ENSOGAP00000011839	Uncharacterized protein.	EPH receptor B1.	0.515
CDC42	EPHB2	ENSOGAP00000012779	ENSOGAP00000013158	Uncharacterized protein.	EPH receptor B2.	0.515
CDC42	EPHB3	ENSOGAP00000012779	ENSOGAP00000017746	Uncharacterized protein.	EPH receptor B3.	0.477
CDC42	H0XQZ6_OTOGA	ENSOGAP00000012779	ENSOGAP00000018538	Uncharacterized protein.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.842
CDC42	PAK3	ENSOGAP00000012779	ENSOGAP00000014106	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.958
CDC42	SHANK1	ENSOGAP00000012779	ENSOGAP00000017779	Uncharacterized protein.	SH3 and multiple ankyrin repeat domains 1.	0.877
CDC42	SHANK3	ENSOGAP00000012779	ENSOGAP00000016208	Uncharacterized protein.	SH3 and multiple ankyrin repeat domains 3.	0.878
CDC42	WASL	ENSOGAP00000012779	ENSOGAP00000006816	Uncharacterized protein.	WASP like actin nucleation promoting factor.	0.963
CTNND2	CDC42	ENSOGAP00000004842	ENSOGAP00000012779	Catenin delta 2.	Uncharacterized protein.	0.652
CTNND2	PAK3	ENSOGAP00000004842	ENSOGAP00000014106	Catenin delta 2.	Non-specific serine/threonine protein kinase.	0.473
DLG4	CDC42	ENSOGAP00000003912	ENSOGAP00000012779	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	Uncharacterized protein.	0.542
DLG4	H0XQZ6_OTOGA	ENSOGAP00000003912	ENSOGAP00000018538	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.760
DLG4	SHANK1	ENSOGAP00000003912	ENSOGAP00000017779	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains 1.	0.909
DLG4	SHANK3	ENSOGAP00000003912	ENSOGAP00000016208	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains 3.	0.886
DOCK10	CDC42	ENSOGAP00000005836	ENSOGAP00000012779	Dedicator of cytokinesis 10; Belongs to the DOCK family.	Uncharacterized protein.	0.935
EPHB1	CDC42	ENSOGAP00000011839	ENSOGAP00000012779	EPH receptor B1.	Uncharacterized protein.	0.515
EPHB1	EPHB3	ENSOGAP00000011839	ENSOGAP00000017746	EPH receptor B1.	EPH receptor B3.	0.749