19 items (Otolemur garnettii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PRKN	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (463 aa)
	PARK7	Parkinsonism associated deglycase. (189 aa)
	DRD2	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
	SLC29A2	Solute carrier family 29 member 2. (459 aa)
	SLC22A2	Solute carrier family 22 member 2. (554 aa)
	SLC22A1	Solute carrier family 22 member 1. (554 aa)
	SLC22A3	Solute carrier family 22 member 3. (421 aa)
	SLC6A2	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (617 aa)
	SLC29A4	Solute carrier family 29 member 4. (532 aa)
	LOC100950564	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (381 aa)
	SLC18A1	Solute carrier family 18 member A1. (518 aa)
	SLC6A12	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (614 aa)
	H0XYR8_OTOGA	Uncharacterized protein. (271 aa)
	CLN8	CLN8 transmembrane ER and ERGIC protein. (288 aa)
	SLC1A7	Amino acid transporter. (574 aa)
	SLC1A2	Amino acid transporter. (576 aa)
	SLC18A2	Solute carrier family 18 member A2. (517 aa)
	SLC6A1	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (602 aa)
	SLC29A1	Solute carrier family 29 member 1 (Augustine blood group). (466 aa)

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DRD2	H0XYR8_OTOGA	ENSOGAP00000005727	ENSOGAP00000021261	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.733
DRD2	LOC100950564	ENSOGAP00000005727	ENSOGAP00000000735	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.733
DRD2	SLC18A2	ENSOGAP00000005727	ENSOGAP00000017944	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	Solute carrier family 18 member A2.	0.468
DRD2	SLC6A2	ENSOGAP00000005727	ENSOGAP00000003773	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.782
H0XYR8_OTOGA	DRD2	ENSOGAP00000021261	ENSOGAP00000005727	Uncharacterized protein.	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	0.733
H0XYR8_OTOGA	LOC100950564	ENSOGAP00000021261	ENSOGAP00000000735	Uncharacterized protein.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.879
H0XYR8_OTOGA	SLC18A2	ENSOGAP00000021261	ENSOGAP00000017944	Uncharacterized protein.	Solute carrier family 18 member A2.	0.464
H0XYR8_OTOGA	SLC1A2	ENSOGAP00000021261	ENSOGAP00000014538	Uncharacterized protein.	Amino acid transporter.	0.685
H0XYR8_OTOGA	SLC1A7	ENSOGAP00000021261	ENSOGAP00000011931	Uncharacterized protein.	Amino acid transporter.	0.611
H0XYR8_OTOGA	SLC6A1	ENSOGAP00000021261	ENSOGAP00000011693	Uncharacterized protein.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.709
H0XYR8_OTOGA	SLC6A12	ENSOGAP00000021261	ENSOGAP00000000276	Uncharacterized protein.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.475
H0XYR8_OTOGA	SLC6A2	ENSOGAP00000021261	ENSOGAP00000003773	Uncharacterized protein.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.727
LOC100950564	DRD2	ENSOGAP00000000735	ENSOGAP00000005727	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	0.733
LOC100950564	H0XYR8_OTOGA	ENSOGAP00000000735	ENSOGAP00000021261	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	Uncharacterized protein.	0.879
LOC100950564	SLC18A2	ENSOGAP00000000735	ENSOGAP00000017944	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	Solute carrier family 18 member A2.	0.464
LOC100950564	SLC1A2	ENSOGAP00000000735	ENSOGAP00000014538	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	Amino acid transporter.	0.685
LOC100950564	SLC1A7	ENSOGAP00000000735	ENSOGAP00000011931	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	Amino acid transporter.	0.611
LOC100950564	SLC6A1	ENSOGAP00000000735	ENSOGAP00000011693	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.705
LOC100950564	SLC6A12	ENSOGAP00000000735	ENSOGAP00000000276	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.458
LOC100950564	SLC6A2	ENSOGAP00000000735	ENSOGAP00000003773	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.725