Your Input: | |
| | H0XIP2_OTOGA | Uncharacterized protein. (294 aa) |
| | GLDC | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1020 aa) |
| | ACAT1 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (428 aa) |
| | TH | Tyrosine hydroxylase. (494 aa) |
| | CAD | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2223 aa) |
| | GFPT2 | Glutamine-fructose-6-phosphate transaminase 2. (680 aa) |
| | GAD1 | Glutamate decarboxylase 1. (595 aa) |
| | MPST | Sulfurtransferase. (299 aa) |
| | THNSL2 | Threonine synthase like 2. (370 aa) |
| | AASS | Aminoadipate-semialdehyde synthase. (927 aa) |
| | AZIN2 | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (460 aa) |
| | GART | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1010 aa) |
| | NIT2 | Nitrilase family member 2. (279 aa) |
| | APIP | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (227 aa) |
| | SDSL | Serine dehydratase like. (329 aa) |
| | SDS | Serine dehydratase. (330 aa) |
| | MTR | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1265 aa) |
| | H0XD62_OTOGA | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (591 aa) |
| | ACAD8 | Acyl-CoA dehydrogenase family member 8. (413 aa) |
| | PYCR1 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (318 aa) |
| | MECP2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (486 aa) |
| | LOC100963160 | Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (600 aa) |
| | GCLM | Glutamate-cysteine ligase modifier subunit. (274 aa) |
| | PADI3 | Peptidyl arginine deiminase 3. (664 aa) |
| | KYAT3 | Kynurenine aminotransferase 3. (436 aa) |
| | HAL | Histidine ammonia-lyase; Belongs to the PAL/histidase family. (657 aa) |
| | AMDHD1 | Amidohydrolase domain containing 1. (438 aa) |
| | GPT2 | Glutamic--pyruvic transaminase 2. (523 aa) |
| | MSRA | Methionine sulfoxide reductase A. (188 aa) |
| | H0XAI3_OTOGA | Arginase. (323 aa) |
| | FAH | Fumarylacetoacetase. (419 aa) |
| | ILVBL | IlvB acetolactate synthase like; Belongs to the TPP enzyme family. (632 aa) |
| | DGLUCY | D-glutamate cyclase. (621 aa) |
| | BCAT1 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (386 aa) |
| | QDPR | Quinoid dihydropteridine reductase. (243 aa) |
| | ASNSD1 | Glutamine amidotransferase type-2 domain-containing protein. (631 aa) |
| | HMGCLL1 | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. (237 aa) |
| | GPT | Glutamic--pyruvic transaminase. (496 aa) |
| | IDO2 | Indoleamine 2,3-dioxygenase 2. (407 aa) |
| | IDO1 | Indoleamine 2,3-dioxygenase 1. (407 aa) |
| | SHMT1 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (483 aa) |
| | GLS2 | Glutaminase 2. (477 aa) |
| | GNMT | Glycine N-methyltransferase. (295 aa) |
| | ALDH8A1 | Aldehyde dehydrogenase 8 family member A1; Belongs to the aldehyde dehydrogenase family. (487 aa) |
| | AFMID | Arylformamidase. (296 aa) |
| | BCAT2 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (392 aa) |
| | NOS1 | Nitric oxide synthase; Produces nitric oxide (NO). (1434 aa) |
| | THNSL1 | Threonine synthase like 1. (743 aa) |
| | HAAO | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (286 aa) |
| | IL4I1 | Amine oxidase. (531 aa) |
| | MTHFD1 | Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (932 aa) |
| | CSAD | Cysteine sulfinic acid decarboxylase. (581 aa) |
| | DPEP1 | Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (407 aa) |
| | GCAT | Glycine C-acetyltransferase. (419 aa) |
| | SRR | Serine racemase. (339 aa) |
| | ALDH6A1 | Aldehyde dehydrogenase 6 family member A1. (520 aa) |
| | HSD17B10 | Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa) |
| | TAT | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (454 aa) |
| | MTHFD2L | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. (300 aa) |
| | PHGDH | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (529 aa) |
| | ENOPH1 | Enolase-phosphatase 1. (258 aa) |
| | ASNS | Asparagine synthetase [glutamine-hydrolyzing]. (564 aa) |
| | AZIN1 | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (448 aa) |
| | KYNU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. (473 aa) |
| | AMT | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (403 aa) |
| | SHMT2 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa) |
| | ACMSD | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa) |
| | ICMT | Protein-S-isoprenylcysteine O-methyltransferase. (289 aa) |
| | KYAT1 | Cytoplasmic cysteine conjugate-beta lyase isoform a (Predicted). (424 aa) |
| | H0WIV4_OTOGA | Orn_Arg_deC_N domain-containing protein. (358 aa) |
| | AGXT2 | Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (513 aa) |
| | RIDA | Uncharacterized protein. (134 aa) |
| | CTPS2 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (560 aa) |
| | H0WHV0_OTOGA | Fe-ADH domain-containing protein. (469 aa) |
| | MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (697 aa) |
| | LOC100954012 | Epimerase domain-containing protein. (373 aa) |
| | BLMH | Bleomycin hydrolase; Belongs to the peptidase C1 family. (455 aa) |
| | UROC1 | Urocanate hydratase 1. (677 aa) |
| | ALDH4A1 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (552 aa) |
| | MCCC1 | Methylcrotonoyl-CoA carboxylase 1. (654 aa) |
| | GOT2 | Aspartate aminotransferase. (430 aa) |
| | RIMKLA | Ribosomal modification protein rimK like family member A. (391 aa) |
| | AGMAT | Agmatinase; Belongs to the arginase family. (349 aa) |
| | HIBADH | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (336 aa) |
| | ASRGL1 | Asparaginase and isoaspartyl peptidase 1. (312 aa) |
| | TDO2 | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (406 aa) |
| | MAT1A | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (400 aa) |
| | ALDH18A1 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (795 aa) |
| | H0WN67_OTOGA | ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (562 aa) |
| | PPAT | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (517 aa) |
| | PSAT1 | Phosphoserine aminotransferase. (370 aa) |
| | GLS | Glutaminase. (602 aa) |
| | SCLY | Selenocysteine lyase. (445 aa) |
| | MTHFR | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (696 aa) |
| | IVD | Isovaleryl-CoA dehydrogenase. (426 aa) |
| | PLOD2 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (709 aa) |
| | PYCR2 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (320 aa) |
| | KMO | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (470 aa) |
| | DDAH1 | Dimethylarginine dimethylaminohydrolase 1. (285 aa) |
| | DDAH2 | Dimethylarginine dimethylaminohydrolase 2. (285 aa) |
| | BAAT | Bile acid-CoA:amino acid N-acyltransferase. (420 aa) |
| | PSPH | Phosphoserine phosphatase. (225 aa) |
| | HYKK | Hydroxylysine kinase. (376 aa) |
| | ALDH5A1 | Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (535 aa) |
| | SMS | Spermine synthase. (309 aa) |
| | OAT | Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa) |
| | GAD2 | Glutamate decarboxylase 2. (585 aa) |
| | CRYM | Crystallin mu. (310 aa) |
| | RIMKLB | Ribosomal modification protein rimK like family member B. (386 aa) |
| | MTHFS | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (203 aa) |
| | AUH | AU RNA binding methylglutaconyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (336 aa) |
| | GCDH | Glutaryl-CoA dehydrogenase. (438 aa) |
| | SIRT4 | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa) |
| | TTC36 | Tetratricopeptide repeat domain 36. (188 aa) |
| | HAO1 | Hydroxyacid oxidase 1. (372 aa) |
| | MCCC2 | Methylcrotonoyl-CoA carboxylase 2. (564 aa) |
| | HPD | 4-hydroxyphenylpyruvate dioxygenase. (390 aa) |
| | OTC | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (355 aa) |
| | ACADSB | Acyl-CoA dehydrogenase short/branched chain. (433 aa) |
| | BHMT2 | Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism. (363 aa) |
| | GMPS | Guanine monophosphate synthase. (595 aa) |
| | SLC39A8 | Solute carrier family 39 member 8. (460 aa) |
| | AADAT | Aminotran_1_2 domain-containing protein. (427 aa) |
| | FTCD | Formimidoyltransferase cyclodeaminase. (541 aa) |
| | ARG2 | Arginase. (354 aa) |
| | DCT | Dopachrome tautomerase. (521 aa) |
| | H0WXF4_OTOGA | Uncharacterized protein. (174 aa) |
| | MTAP | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (283 aa) |
| | ADI1 | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (179 aa) |
| | GLYAT | Glycine-N-acyltransferase. (296 aa) |
| | ASPA | Aspartoacylase. (313 aa) |
| | PIPOX | Pipecolic acid and sarcosine oxidase. (392 aa) |
| | MRI1 | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (366 aa) |
| | GOT1L1 | Glutamic-oxaloacetic transaminase 1 like 1. (407 aa) |
| | GCLC | Glutamate-cysteine ligase catalytic subunit. (637 aa) |
| | SARDH | Sarcosine dehydrogenase. (921 aa) |
| | BHMT | Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism. (407 aa) |
| | IYD | Iodotyrosine deiodinase. (289 aa) |
| | NOXRED1 | NADP dependent oxidoreductase domain containing 1. (349 aa) |
| | TMED8 | Transmembrane p24 trafficking protein family member 8. (264 aa) |
| | GSTZ1 | Glutathione S-transferase zeta 1; Belongs to the GST superfamily. (217 aa) |
| | PCBD1 | Pterin-4 alpha-carbinolamine dehydratase 1. (103 aa) |
| | PAH | Phenylalanine hydroxylase. (452 aa) |
| | HGD | Homogentisate 1,2-dioxygenase. (445 aa) |
| | GOT1 | Aspartate aminotransferase. (413 aa) |
| | CPS1 | Carbamoyl-phosphate synthase 1. (1505 aa) |
| | PYCR3 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (274 aa) |
| | GLUL | Glutamate-ammonia ligase; Belongs to the glutamine synthetase family. (353 aa) |
| | LOC111728545 | FTCD_N domain-containing protein. (328 aa) |
| | H0Y222_OTOGA | Aminotran_1_2 domain-containing protein. (414 aa) |
| | H0Y1R7_OTOGA | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (398 aa) |
| | LGSN | Lengsin, lens protein with glutamine synthetase domain; Belongs to the glutamine synthetase family. (572 aa) |
| | FPGS | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (587 aa) |
| | DAO | D-amino acid oxidase. (352 aa) |
| | HIBCH | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (215 aa) |
| | H0XXT0_OTOGA | Uncharacterized protein; Belongs to the arginase family. (291 aa) |
| | DDO | D-aspartate oxidase. (341 aa) |
| | THAP8 | THAP domain containing 8. (273 aa) |
| | TST | Sulfurtransferase. (298 aa) |
| | H0XW36_OTOGA | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (174 aa) |
| | PFAS | Phosphoribosylformylglycinamidine synthase. (1338 aa) |
| | H0XUV2_OTOGA | Aminotran_1_2 domain-containing protein. (425 aa) |
| | H0XUH1_OTOGA | Uncharacterized protein. (132 aa) |
| | H0XUE2_OTOGA | Uncharacterized protein. (212 aa) |
| | NAGS | N-acetylglutamate synthase. (522 aa) |
| | H0XTG5_OTOGA | PABS domain-containing protein. (332 aa) |
| | LOC100961661 | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (173 aa) |
| | ASPG | Asparaginase. (482 aa) |
| | ASS1 | Argininosuccinate synthase 1. (414 aa) |
| | GFPT1 | Glutamine--fructose-6-phosphate transaminase 1. (682 aa) |
| | DLST | Dihydrolipoamide S-succinyltransferase. (455 aa) |
| | HNF4A | Hepatocyte nuclear factor 4 alpha. (476 aa) |
| | H0XQ29_OTOGA | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa) |
| | ASL | Argininosuccinate lyase. (464 aa) |
| | THAP4 | THAP domain containing 4. (553 aa) |
| | PRODH2 | Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (460 aa) |
| | CBS | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (567 aa) |
| | PLOD3 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (744 aa) |
| | ATF4 | Activating transcription factor 4. (352 aa) |
| | NAT8L | N-acetyltransferase 8 like. (259 aa) |
| | DHFR | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa) |
| | MMUT | Methylmalonyl-CoA mutase. (755 aa) |
