STRINGSTRING
EIF4A3 EIF4A3 PRPF6 PRPF6 H0WWM8_OTOGA H0WWM8_OTOGA SNRPD1 SNRPD1 RBMX RBMX ESS2 ESS2 DHX16 DHX16 CDC40 CDC40 SNIP1 SNIP1 DHX38 DHX38 CWC25 CWC25 RBMXL2 RBMXL2 WBP4 WBP4 XAB2 XAB2 SNW1 SNW1 SNRPC-2 SNRPC-2 SNRPC SNRPC H0XX70_OTOGA H0XX70_OTOGA H0XX05_OTOGA H0XX05_OTOGA H0XWX1_OTOGA H0XWX1_OTOGA H0XWW2_OTOGA H0XWW2_OTOGA SNRPD2 SNRPD2 H0XW89_OTOGA H0XW89_OTOGA PRPF4B PRPF4B SNRPD3 SNRPD3 H0XV55_OTOGA H0XV55_OTOGA SNRNP70 SNRNP70 H0XUH9_OTOGA H0XUH9_OTOGA H0XUF6_OTOGA H0XUF6_OTOGA H0XU53_OTOGA H0XU53_OTOGA H0XTQ5_OTOGA H0XTQ5_OTOGA RNPC3 RNPC3 SRRM3 SRRM3 SF3A2 SF3A2 H0XSR3_OTOGA H0XSR3_OTOGA H0XS58_OTOGA H0XS58_OTOGA H0XS57_OTOGA H0XS57_OTOGA LOC100957263 LOC100957263 LOC100952049 LOC100952049 H0XPT1_OTOGA H0XPT1_OTOGA PRPF38B PRPF38B H0XMN3_OTOGA H0XMN3_OTOGA H0XMI7_OTOGA H0XMI7_OTOGA H0XMB9_OTOGA H0XMB9_OTOGA H0XMB5_OTOGA H0XMB5_OTOGA H0XLZ3_OTOGA H0XLZ3_OTOGA RBM5 RBM5 H0XL48_OTOGA H0XL48_OTOGA CWC15 CWC15 HNRNPM HNRNPM H0XJY8_OTOGA H0XJY8_OTOGA H0XJX1_OTOGA H0XJX1_OTOGA RALY RALY H0XIA1_OTOGA H0XIA1_OTOGA H0XI54_OTOGA H0XI54_OTOGA H0XHN1_OTOGA H0XHN1_OTOGA CCDC12 CCDC12 FMC1-LUC7L2 FMC1-LUC7L2 SART1 SART1 ZMAT5 ZMAT5 EFL1 EFL1 UHRF1BP1 UHRF1BP1 IVNS1ABP IVNS1ABP SF1 SF1 SNRPB SNRPB AQR AQR SNRPG SNRPG CWC22 CWC22 SNRPB2 SNRPB2 PRPF40A PRPF40A H0XAZ5_OTOGA H0XAZ5_OTOGA IK IK LOC100964496 LOC100964496 API5 API5 CWF19L1 CWF19L1 ZCRB1 ZCRB1 SF3A1 SF3A1 EFTUD2 EFTUD2 UPF1 UPF1 WDR83 WDR83 H0X760_OTOGA H0X760_OTOGA HNRNPH3 HNRNPH3 ALYREF ALYREF SF3B5 SF3B5 SF3A3 SF3A3 MTHFSD MTHFSD CWF19L2 CWF19L2 CRNKL1 CRNKL1 CTNNBL1 CTNNBL1 SNRNP35 SNRNP35 PPIL1 PPIL1 DDX41 DDX41 RBM22 RBM22 MYEF2 MYEF2 BUD31 BUD31 PPWD1 PPWD1 TFIP11 TFIP11 DHX8 DHX8 CACTIN CACTIN SRRM1 SRRM1 MFAP1 MFAP1 SYF2 SYF2 H0X0J6_OTOGA H0X0J6_OTOGA UBE2J1 UBE2J1 RBM41 RBM41 HNRNPR HNRNPR H0XYH4_OTOGA H0XYH4_OTOGA H0XZ99_OTOGA H0XZ99_OTOGA H0XZC7_OTOGA H0XZC7_OTOGA RNF113A RNF113A H0XZL8_OTOGA H0XZL8_OTOGA PRPF39 PRPF39 SRRM2 SRRM2 H0Y1C6_OTOGA H0Y1C6_OTOGA SNRPC-3 SNRPC-3 H0Y1K1_OTOGA H0Y1K1_OTOGA H0XY77_OTOGA H0XY77_OTOGA WDR25 WDR25 PTBP2 PTBP2 SLA2 SLA2 DHX35 DHX35 CCDC130 CCDC130 GCFC2 GCFC2 H0WJ36_OTOGA H0WJ36_OTOGA ZMAT2 ZMAT2 HNRNPDL HNRNPDL SNRNP25 SNRNP25 H0WLK5_OTOGA H0WLK5_OTOGA SNRPA SNRPA MTREX MTREX PPIE PPIE GPKOW GPKOW GPATCH1 GPATCH1 SMU1 SMU1 SF3B6 SF3B6 LUC7L3 LUC7L3 SNRNP40 SNRNP40 H0WRF0_OTOGA H0WRF0_OTOGA SNRNP48 SNRNP48 PRPF38A PRPF38A ADAR ADAR SF3B2 SF3B2 H0WTS0_OTOGA H0WTS0_OTOGA SF3B4 SF3B4 SNRNP200 SNRNP200 CWC27 CWC27 H0WVK2_OTOGA H0WVK2_OTOGA U2AF2 U2AF2 PRPF18 PRPF18 SNRPN SNRPN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EIF4A3Uncharacterized protein; Belongs to the DEAD box helicase family. (411 aa)
PRPF6Pre-mRNA processing factor 6. (930 aa)
H0WWM8_OTOGAUncharacterized protein. (794 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
RBMXRRM domain-containing protein. (500 aa)
ESS2Ess-2 splicing factor homolog. (478 aa)
DHX16DEAH-box helicase 16. (1044 aa)
CDC40Cell division cycle 40. (579 aa)
SNIP1Smad nuclear interacting protein 1. (390 aa)
DHX38DEAH-box helicase 38. (1229 aa)
CWC25CWC25 spliceosome associated protein homolog. (389 aa)
RBMXL2RRM domain-containing protein. (393 aa)
WBP4WW domain binding protein 4. (383 aa)
XAB2XPA binding protein 2. (855 aa)
SNW1SNW domain containing 1. (536 aa)
SNRPC-2U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (178 aa)
SNRPCU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (152 aa)
H0XX70_OTOGAUncharacterized protein. (104 aa)
H0XX05_OTOGARRM domain-containing protein. (297 aa)
H0XWX1_OTOGARRM domain-containing protein. (294 aa)
H0XWW2_OTOGARRM domain-containing protein. (293 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (117 aa)
H0XW89_OTOGAUncharacterized protein. (360 aa)
PRPF4BPre-mRNA processing factor 4B. (1007 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (148 aa)
H0XV55_OTOGAUncharacterized protein. (217 aa)
SNRNP70Small nuclear ribonucleoprotein U1 subunit 70. (440 aa)
H0XUH9_OTOGARRM domain-containing protein. (302 aa)
H0XUF6_OTOGAUncharacterized protein. (468 aa)
H0XU53_OTOGAUncharacterized protein. (208 aa)
H0XTQ5_OTOGAUncharacterized protein. (110 aa)
RNPC3RNA binding region (RNP1, RRM) containing 3. (519 aa)
SRRM3Serine/arginine repetitive matrix 3. (654 aa)
SF3A2Splicing factor 3a subunit 2. (464 aa)
H0XSR3_OTOGAUncharacterized protein. (429 aa)
H0XS58_OTOGARRM domain-containing protein. (213 aa)
H0XS57_OTOGARRM domain-containing protein. (301 aa)
LOC100957263Sm domain-containing protein. (86 aa)
LOC100952049Uncharacterized protein. (341 aa)
H0XPT1_OTOGAUncharacterized protein. (296 aa)
PRPF38BUncharacterized protein. (547 aa)
H0XMN3_OTOGAWD_REPEATS_REGION domain-containing protein. (331 aa)
H0XMI7_OTOGARRM domain-containing protein. (211 aa)
H0XMB9_OTOGARRM domain-containing protein. (416 aa)
H0XMB5_OTOGAUncharacterized protein. (319 aa)
H0XLZ3_OTOGAUncharacterized protein. (382 aa)
RBM5RNA binding motif protein 5. (760 aa)
H0XL48_OTOGATuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (799 aa)
CWC15CWC15 spliceosome associated protein homolog. (231 aa)
HNRNPMHeterogeneous nuclear ribonucleoprotein M. (704 aa)
H0XJY8_OTOGAUncharacterized protein. (345 aa)
H0XJX1_OTOGARRM domain-containing protein. (159 aa)
RALYRALY heterogeneous nuclear ribonucleoprotein. (312 aa)
H0XIA1_OTOGAUncharacterized protein. (792 aa)
H0XI54_OTOGAUncharacterized protein. (322 aa)
H0XHN1_OTOGAUncharacterized protein. (398 aa)
CCDC12Coiled-coil domain containing 12. (112 aa)
FMC1-LUC7L2FMC1-LUC7L2 readthrough. (458 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (801 aa)
ZMAT5Zinc finger matrin-type 5. (170 aa)
EFL1Elongation factor like GTPase 1. (865 aa)
UHRF1BP1UHRF1 binding protein 1. (1440 aa)
IVNS1ABPInfluenza virus NS1A binding protein. (642 aa)
SF1Splicing factor 1 isoform 2 (Predicted). (637 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (240 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1500 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (73 aa)
CWC22CWC22 spliceosome associated protein homolog. (909 aa)
SNRPB2Small nuclear ribonucleoprotein polypeptide B2. (225 aa)
PRPF40APre-mRNA processing factor 40 homolog A. (938 aa)
H0XAZ5_OTOGASm domain-containing protein. (53 aa)
IKIK cytokine. (557 aa)
LOC100964496Uncharacterized protein. (416 aa)
API5Apoptosis inhibitor 5. (526 aa)
CWF19L1CWF19 like cell cycle control factor 1. (543 aa)
ZCRB1Uncharacterized protein. (217 aa)
SF3A1Splicing factor 3a subunit 1. (793 aa)
EFTUD2Elongation factor Tu GTP binding domain containing 2. (969 aa)
UPF1UPF1 RNA helicase and ATPase. (1118 aa)
WDR83WD repeat domain 83. (315 aa)
H0X760_OTOGARRM domain-containing protein. (295 aa)
HNRNPH3Heterogeneous nuclear ribonucleoprotein H3. (346 aa)
ALYREFAly/REF export factor. (233 aa)
SF3B5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
SF3A3Splicing factor 3a subunit 3. (401 aa)
MTHFSDMethenyltetrahydrofolate synthetase domain containing. (382 aa)
CWF19L2CWF19 like cell cycle control factor 2. (856 aa)
CRNKL1Crooked neck pre-mRNA splicing factor 1. (687 aa)
CTNNBL1Catenin beta like 1. (563 aa)
SNRNP35Small nuclear ribonucleoprotein U11/U12 subunit 35. (246 aa)
PPIL1Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
DDX41Uncharacterized protein. (622 aa)
RBM22RNA binding motif protein 22. (421 aa)
MYEF2Myelin expression factor 2. (601 aa)
BUD31BUD31 homolog. (144 aa)
PPWD1Peptidylprolyl isomerase domain and WD repeat containing 1. (645 aa)
TFIP11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (837 aa)
DHX8DEAH-box helicase 8. (1220 aa)
CACTINCactin, spliceosome C complex subunit. (677 aa)
SRRM1Serine and arginine repetitive matrix 1. (916 aa)
MFAP1Microfibrillar-associated protein 1 (Predicted). (439 aa)
SYF2SYF2 pre-mRNA splicing factor. (244 aa)
H0X0J6_OTOGAUncharacterized protein. (191 aa)
UBE2J1Ubiquitin conjugating enzyme E2 J1. (311 aa)
RBM41RNA binding motif protein 41. (412 aa)
HNRNPRUncharacterized protein. (633 aa)
H0XYH4_OTOGARRM domain-containing protein. (295 aa)
H0XZ99_OTOGAUncharacterized protein. (469 aa)
H0XZC7_OTOGARRM domain-containing protein. (285 aa)
RNF113AUncharacterized protein. (344 aa)
H0XZL8_OTOGAUncharacterized protein. (227 aa)
PRPF39Pre-mRNA processing factor 39. (669 aa)
SRRM2Serine/arginine repetitive matrix 2. (2727 aa)
H0Y1C6_OTOGAUncharacterized protein; Belongs to the DEAD box helicase family. (411 aa)
SNRPC-3U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (159 aa)
H0Y1K1_OTOGAUncharacterized protein. (293 aa)
H0XY77_OTOGARRM domain-containing protein. (331 aa)
WDR25WD repeat domain 25. (534 aa)
PTBP2Polypyrimidine tract binding protein 2. (540 aa)
SLA2Src like adaptor 2. (259 aa)
DHX35DEAH-box helicase 35. (679 aa)
CCDC130Coiled-coil domain containing 130. (392 aa)
GCFC2GC-rich sequence DNA-binding factor 2. (612 aa)
H0WJ36_OTOGAUncharacterized protein. (322 aa)
ZMAT2Zinc finger matrin-type 2. (199 aa)
HNRNPDLHeterogeneous nuclear ribonucleoprotein D like. (418 aa)
SNRNP25Small nuclear ribonucleoprotein U11/U12 subunit 25. (159 aa)
H0WLK5_OTOGAUncharacterized protein. (102 aa)
SNRPASmall nuclear ribonucleoprotein polypeptide A. (282 aa)
MTREXMtr4 exosome RNA helicase. (1042 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (304 aa)
GPKOWG-patch domain and KOW motifs. (476 aa)
GPATCH1G-patch domain containing 1. (790 aa)
SMU1SMU1 DNA replication regulator and spliceosomal factor. (515 aa)
SF3B6Splicing factor 3b subunit 6. (125 aa)
LUC7L3LUC7 like 3 pre-mRNA splicing factor. (434 aa)
SNRNP40WD_REPEATS_REGION domain-containing protein. (358 aa)
H0WRF0_OTOGAUncharacterized protein. (285 aa)
SNRNP48Small nuclear ribonucleoprotein U11/U12 subunit 48. (330 aa)
PRPF38APre-mRNA processing factor 38A. (312 aa)
ADARAdenosine deaminase RNA specific. (1157 aa)
SF3B2Splicing factor 3b subunit 2. (893 aa)
H0WTS0_OTOGARRM domain-containing protein. (326 aa)
SF3B4Splicing factor 3b subunit 4. (424 aa)
SNRNP200Small nuclear ribonucleoprotein U5 subunit 200. (2136 aa)
CWC27CWC27 spliceosome associated cyclophilin. (472 aa)
H0WVK2_OTOGAPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (139 aa)
U2AF2U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (475 aa)
PRPF18SFM domain-containing protein. (342 aa)
SNRPNSmall nuclear ribonucleoprotein-associated protein. (240 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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