(5 nodes) MHC class II, alpha chain, N-terminal network (Otolemur garnettii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100957736	Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa)
	HLA-DRA	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (262 aa)
	HLA-DOA	Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (255 aa)
	HLA-DMA	Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (261 aa)
	HLA-DPA1	Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (266 aa)

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HLA-DMA	HLA-DOA	ENSOGAP00000005388	ENSOGAP00000013157	Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family.	Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family.	0.998
HLA-DMA	HLA-DPA1	ENSOGAP00000005388	ENSOGAP00000005791	Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family.	Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family.	0.996
HLA-DMA	HLA-DRA	ENSOGAP00000005388	ENSOGAP00000007523	Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family.	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	0.998
HLA-DMA	LOC100957736	ENSOGAP00000005388	ENSOGAP00000007525	Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.971
HLA-DOA	HLA-DMA	ENSOGAP00000013157	ENSOGAP00000005388	Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family.	Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family.	0.998
HLA-DOA	HLA-DPA1	ENSOGAP00000013157	ENSOGAP00000005791	Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family.	Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family.	0.992
HLA-DOA	HLA-DRA	ENSOGAP00000013157	ENSOGAP00000007523	Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family.	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	0.920
HLA-DOA	LOC100957736	ENSOGAP00000013157	ENSOGAP00000007525	Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.951
HLA-DPA1	HLA-DMA	ENSOGAP00000005791	ENSOGAP00000005388	Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family.	Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family.	0.996
HLA-DPA1	HLA-DOA	ENSOGAP00000005791	ENSOGAP00000013157	Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family.	Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family.	0.992
HLA-DPA1	HLA-DRA	ENSOGAP00000005791	ENSOGAP00000007523	Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family.	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	0.995
HLA-DPA1	LOC100957736	ENSOGAP00000005791	ENSOGAP00000007525	Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.935
HLA-DRA	HLA-DMA	ENSOGAP00000007523	ENSOGAP00000005388	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family.	0.998
HLA-DRA	HLA-DOA	ENSOGAP00000007523	ENSOGAP00000013157	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family.	0.920
HLA-DRA	HLA-DPA1	ENSOGAP00000007523	ENSOGAP00000005791	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family.	0.995
HLA-DRA	LOC100957736	ENSOGAP00000007523	ENSOGAP00000007525	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.956
LOC100957736	HLA-DMA	ENSOGAP00000007525	ENSOGAP00000005388	Ig-like domain-containing protein; Belongs to the MHC class II family.	Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family.	0.971
LOC100957736	HLA-DOA	ENSOGAP00000007525	ENSOGAP00000013157	Ig-like domain-containing protein; Belongs to the MHC class II family.	Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family.	0.951
LOC100957736	HLA-DPA1	ENSOGAP00000007525	ENSOGAP00000005791	Ig-like domain-containing protein; Belongs to the MHC class II family.	Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family.	0.935
LOC100957736	HLA-DRA	ENSOGAP00000007525	ENSOGAP00000007523	Ig-like domain-containing protein; Belongs to the MHC class II family.	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	0.956