STRINGSTRING
KCNV1 KCNV1 GRIK3 GRIK3 SCN3A SCN3A SCN2A SCN2A ATP6V1C1 ATP6V1C1 KCNK1 KCNK1 BEST3 BEST3 CHRNB1 CHRNB1 KCNK5 KCNK5 KCNK17 KCNK17 KCNK16 KCNK16 CACNA1I CACNA1I CHRNA6 CHRNA6 CNGA4 CNGA4 GABRR1 GABRR1 GABRE GABRE CACNG2 CACNG2 SLCO1A2 SLCO1A2 CHRNA4 CHRNA4 SLC9A6 SLC9A6 SLC4A5 SLC4A5 ATP4B ATP4B SLC4A9 SLC4A9 ATP5MC2 ATP5MC2 ATP12A ATP12A KCNK6 KCNK6 HTR3A HTR3A ASIC5 ASIC5 SLC9A9 SLC9A9 CLCN7 CLCN7 KCNK10 KCNK10 TRPV1 TRPV1 P2RX7 P2RX7 CACNA1G CACNA1G ASIC1 ASIC1 H0WQJ9_OTOGA H0WQJ9_OTOGA GRID2 GRID2 KCNH3 KCNH3 SLCO4A1 SLCO4A1 SLC4A8 SLC4A8 SCN8A SCN8A KCNA6 KCNA6 SLCO2A1 SLCO2A1 KCNJ3 KCNJ3 GLRA4 GLRA4 CHRNA9 CHRNA9 GRIN2D GRIN2D KCNJ14 KCNJ14 TRPC5 TRPC5 SLC9A7 SLC9A7 TRPV2 TRPV2 KCNH1 KCNH1 P2RX2 P2RX2 SLC4A1 SLC4A1 KCNK3 KCNK3 ATP2A1 ATP2A1 BEST4 BEST4 CHRNA10 CHRNA10 LOC100942563 LOC100942563 KCNK4 KCNK4 SLC9A8 SLC9A8 CLCN5 CLCN5 KCNK18 KCNK18 TRPV3 TRPV3 KCNJ15 KCNJ15 SLCO3A1 SLCO3A1 GLRA2 GLRA2 KCNH2 KCNH2 HCN2 HCN2 CACNG7 CACNG7 CACNG6 CACNG6 CLCN3 CLCN3 PANX3 PANX3 ATP2B1 ATP2B1 ATP1B3 ATP1B3 SLC10A7 SLC10A7 P2RX1 P2RX1 ATP2A3 ATP2A3 ATP6V1H ATP6V1H HCN1 HCN1 ATP2B3 ATP2B3 GRIA4 GRIA4 CHRND CHRND H0X016_OTOGA H0X016_OTOGA ATP6V0D2 ATP6V0D2 SCN11A SCN11A KCNG4 KCNG4 ATP2C2 ATP2C2 GABRR2 GABRR2 ATP1B2 ATP1B2 HCN3 HCN3 TRPC7 TRPC7 GRIK2 GRIK2 GRIK1 GRIK1 CHRNE CHRNE ATP6V1C2 ATP6V1C2 ATP6V1F ATP6V1F KCNJ13 KCNJ13 ATP6V0A1 ATP6V0A1 KCNQ2 KCNQ2 SLC9A3 SLC9A3 SLC4A4 SLC4A4 ATP1B1 ATP1B1 ATP6V1G1 ATP6V1G1 CACNA1F CACNA1F GRIA1 GRIA1 KCND3 KCND3 SLCO4C1 SLCO4C1 CHRNA3 CHRNA3 CHRNB4 CHRNB4 GABRA1 GABRA1 GABRG2 GABRG2 CACNA1C CACNA1C SCNN1B SCNN1B TRPC4 TRPC4 KCNC1 KCNC1 TRPA1 TRPA1 ATP1A2 ATP1A2 SLCO2B1 SLCO2B1 KCNH5 KCNH5 TMCO1 TMCO1 SCN5A SCN5A SCNN1A SCNN1A TTYH3 TTYH3 GABRR3 GABRR3 KCNK15 KCNK15 SLC4A10 SLC4A10 KCNH7 KCNH7 KCNQ4 KCNQ4 GABRG1 GABRG1 KCNQ3 KCNQ3 SCN9A SCN9A KCNJ5 KCNJ5 GABRQ GABRQ CLIC3 CLIC3 GABRA3 GABRA3 ATP2A2 ATP2A2 TRPV6 TRPV6 TRPV5 TRPV5 CLCN1 CLCN1 GABRP GABRP CACNG4 CACNG4 GRIN3B GRIN3B SLC40A1 SLC40A1 GLRB GLRB GRIA2 GRIA2 GABRA4 GABRA4 H0X9U7_OTOGA H0X9U7_OTOGA KCNK9 KCNK9 SLC9A4 SLC9A4 KCNK7 KCNK7 ATP6V0A4 ATP6V0A4 CNGA2 CNGA2 KCNH4 KCNH4 KCND2 KCND2 KCNK12 KCNK12 PANX2 PANX2 KCNJ8 KCNJ8 KCNA4 KCNA4 TCIRG1 TCIRG1 ATP5MC1 ATP5MC1 KCNA5 KCNA5 KCNH6 KCNH6 ASIC3 ASIC3 KCNA1 KCNA1 KCNC4 KCNC4 CACNG8 CACNG8 BEST1 BEST1 P2RX4 P2RX4 H0Y230_OTOGA H0Y230_OTOGA ATP1B4 ATP1B4 KCNA3 KCNA3 KCNG2 KCNG2 KCNC3 KCNC3 H0XMA0_OTOGA H0XMA0_OTOGA KCNF1 KCNF1 KCNQ5 KCNQ5 H0XMV8_OTOGA H0XMV8_OTOGA H0XN94_OTOGA H0XN94_OTOGA CLIC5 CLIC5 FXYD1 FXYD1 CLCN4 CLCN4 CLIC4 CLIC4 SCN10A SCN10A P2RX3 P2RX3 SLC4A7 SLC4A7 SCN7A SCN7A TRPV4 TRPV4 ATP5F1C ATP5F1C PANX1 PANX1 ATP6V1B1 ATP6V1B1 FXYD6 FXYD6 KCNJ6 KCNJ6 GRIK5 GRIK5 SLC9A2 SLC9A2 ASIC2 ASIC2 GLRA3 GLRA3 SLC26A1 SLC26A1 GRIN3A GRIN3A MRS2 MRS2 ATP2C1 ATP2C1 HTR3C HTR3C TRPC3 TRPC3 ATP5MG ATP5MG ATP6V1G3 ATP6V1G3 CACNA1B CACNA1B GRIN2B GRIN2B TTYH1 TTYH1 GABRD GABRD GRIN2C GRIN2C CACNA1D CACNA1D ATP2B2 ATP2B2 ATP6V0E1 ATP6V0E1 CHRNB3 CHRNB3 H0XNK0_OTOGA H0XNK0_OTOGA KCNG1 KCNG1 CLCN6 CLCN6 ATP6V0C ATP6V0C KCNJ16 KCNJ16 GABRB2 GABRB2 H0XPH7_OTOGA H0XPH7_OTOGA GABRA6 GABRA6 H0XQ52_OTOGA H0XQ52_OTOGA H0XQ59_OTOGA H0XQ59_OTOGA KCNS1 KCNS1 H0XQK1_OTOGA H0XQK1_OTOGA KCNA10 KCNA10 KCNS3 KCNS3 KCNJ2 KCNJ2 CLCN2 CLCN2 SCNM1 SCNM1 CHRNA5 CHRNA5 SCARA5 SCARA5 CNGA3 CNGA3 KCNS2 KCNS2 CNGA1 CNGA1 KCNV2 KCNV2 KCNG3 KCNG3 KCNJ9 KCNJ9 KCNJ4 KCNJ4 ATP5MC3 ATP5MC3 HCN4 HCN4 CHRNA2 CHRNA2 CHRNB2 CHRNB2 H0XUZ7_OTOGA H0XUZ7_OTOGA GABRA2 GABRA2 ASIC4 ASIC4 KCNJ11 KCNJ11 PIEZO1 PIEZO1 KCNA2 KCNA2 PIEZO2 PIEZO2 BEST2 BEST2 ATP4A ATP4A GABRB3 GABRB3 KCNB1 KCNB1 KCNJ1 KCNJ1 CACNG1 CACNG1 GRIN1 GRIN1 ATP6V1G2 ATP6V1G2 KCNK13 KCNK13 CACNG3 CACNG3 SCN4A SCN4A CLIC1 CLIC1 CLIC6 CLIC6 KCND1 KCND1 CHRNG CHRNG KCNH8 KCNH8 KCNC2 KCNC2 TRPC6 TRPC6 TRPC1 TRPC1 SCNN1G SCNN1G GABRA5 GABRA5 SLC4A3 SLC4A3 ATP6V1B2 ATP6V1B2 ATP2B4 ATP2B4 ATP1A1 ATP1A1 KCNJ12 KCNJ12 ATP6V0D1 ATP6V0D1 SLC9A5 SLC9A5 TTYH2 TTYH2 SLCO1C1 SLCO1C1 KCNJ10 KCNJ10 CHRNA1 CHRNA1 CACNA1E CACNA1E KCNA7 KCNA7 ATP6V0B ATP6V0B GRID1 GRID1 KCNQ1 KCNQ1 GRIK4 GRIK4 CACNA1A CACNA1A GLRA1 GLRA1 CFTR CFTR SLC4A2 SLC4A2 CACNA1S CACNA1S ATP5PD ATP5PD SLC9A1 SLC9A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KCNV1Potassium voltage-gated channel modifier subfamily V member 1; Belongs to the potassium channel family. (501 aa)
GRIK3Glutamate ionotropic receptor kainate type subunit 3. (890 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2002 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1991 aa)
ATP6V1C1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
KCNK1Potassium channel subfamily K member. (336 aa)
BEST3Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (367 aa)
CHRNB1Cholinergic receptor nicotinic beta 1 subunit. (502 aa)
KCNK5Potassium two pore domain channel subfamily K member 5; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (500 aa)
KCNK17Potassium channel subfamily K member. (332 aa)
KCNK16Potassium two pore domain channel subfamily K member 16; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (294 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2152 aa)
CHRNA6Cholinergic receptor nicotinic alpha 6 subunit. (494 aa)
CNGA4Cyclic nucleotide gated channel subunit alpha 4. (575 aa)
GABRR1Gamma-aminobutyric acid type A receptor rho1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (439 aa)
GABREGamma-aminobutyric acid type A receptor epsilon subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (400 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
SLCO1A2Solute carrier organic anion transporter family member. (671 aa)
CHRNA4Cholinergic receptor nicotinic alpha 4 subunit. (621 aa)
SLC9A6Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (703 aa)
SLC4A5Anion exchange protein. (931 aa)
ATP4BSodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (291 aa)
SLC4A9Anion exchange protein. (980 aa)
ATP5MC2ATP synthase membrane subunit c locus 2; Belongs to the ATPase C chain family. (190 aa)
ATP12ASodium/potassium-transporting ATPase subunit alpha. (1026 aa)
KCNK6Potassium channel subfamily K member. (313 aa)
HTR3A5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (489 aa)
ASIC5Acid sensing ion channel subunit family member 5; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (509 aa)
SLC9A9Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (645 aa)
CLCN7Chloride channel protein. (805 aa)
KCNK10Potassium two pore domain channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (543 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (840 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2342 aa)
ASIC1Acid sensing ion channel subunit 1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (518 aa)
H0WQJ9_OTOGASodium/potassium-transporting ATPase subunit alpha. (1022 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (706 aa)
KCNH3Potassium voltage-gated channel subfamily H member 3. (1084 aa)
SLCO4A1Solute carrier organic anion transporter family member. (726 aa)
SLC4A8Anion exchange protein. (1104 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1863 aa)
KCNA6Potassium voltage-gated channel subfamily A member 6; Belongs to the potassium channel family. (530 aa)
SLCO2A1Solute carrier organic anion transporter family member. (619 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
GLRA4Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)
CHRNA9Cholinergic receptor nicotinic alpha 9 subunit. (482 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (1332 aa)
KCNJ14Potassium voltage-gated channel subfamily J member 14. (434 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
SLC9A7Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (644 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (771 aa)
KCNH1Potassium voltage-gated channel subfamily H member 1. (962 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (484 aa)
SLC4A1Anion exchange protein. (926 aa)
KCNK3Potassium channel subfamily K member. (343 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1001 aa)
BEST4Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (467 aa)
CHRNA10Cholinergic receptor nicotinic alpha 10 subunit. (453 aa)
LOC100942563Chloride channel protein. (687 aa)
KCNK4Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (393 aa)
SLC9A8Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (581 aa)
CLCN5Chloride channel protein. (816 aa)
KCNK18Potassium two pore domain channel subfamily K member 18; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (380 aa)
TRPV3Transient receptor potential cation channel subfamily V member 3; Belongs to the transient receptor (TC 1.A.4) family. (793 aa)
KCNJ15Potassium voltage-gated channel subfamily J member 15. (376 aa)
SLCO3A1Solute carrier organic anion transporter family member. (710 aa)
GLRA2Glycine receptor alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (453 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1162 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (848 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (260 aa)
CLCN3Chloride channel protein. (866 aa)
PANX3Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (392 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1259 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (243 aa)
SLC10A7Sodium/bile acid cotransporter; Does not show transport activity towards bile acids or steroid sulfates; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. (343 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1002 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (477 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (879 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (733 aa)
CHRNDCholinergic receptor nicotinic delta subunit. (517 aa)
H0X016_OTOGANeur_chan_memb domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (276 aa)
ATP6V0D2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
SCN11ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1770 aa)
KCNG4Potassium voltage-gated channel modifier subfamily G member 4; Belongs to the potassium channel family. (516 aa)
ATP2C2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (815 aa)
GABRR2Gamma-aminobutyric acid type A receptor rho2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (398 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (780 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (912 aa)
GRIK1Glutamate ionotropic receptor kainate type subunit 1. (677 aa)
CHRNECholinergic receptor nicotinic epsilon subunit. (513 aa)
ATP6V1C2V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (427 aa)
ATP6V1FV-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (145 aa)
KCNJ13Potassium voltage-gated channel subfamily J member 13. (360 aa)
ATP6V0A1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (838 aa)
KCNQ2Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family. (856 aa)
SLC9A3Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (838 aa)
SLC4A4Anion exchange protein. (1003 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
ATP6V1G1V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1976 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (867 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (655 aa)
SLCO4C1Solute carrier organic anion transporter family member. (727 aa)
CHRNA3Cholinergic receptor nicotinic alpha 3 subunit. (499 aa)
CHRNB4Cholinergic receptor nicotinic beta 4 subunit. (504 aa)
GABRA1Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
GABRG2Gamma-aminobutyric acid type A receptor gamma2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (475 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2005 aa)
SCNN1BSodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (636 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (971 aa)
KCNC1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (585 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1118 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
SLCO2B1Solute carrier organic anion transporter family member. (707 aa)
KCNH5Potassium voltage-gated channel subfamily H member 5. (988 aa)
TMCO1Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling; Belongs to the TMCO1 family. (187 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2020 aa)
SCNN1ASodium channel epithelial 1 alpha subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (687 aa)
TTYH3Protein tweety homolog; Probable chloride channel; Belongs to the tweety family. (525 aa)
GABRR3Gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene); Belongs to the ligand-gated ion channel (TC 1.A.9) family. (470 aa)
KCNK15Potassium channel subfamily K member. (312 aa)
SLC4A10Anion exchange protein. (1087 aa)
KCNH7Potassium voltage-gated channel subfamily H member 7. (1099 aa)
KCNQ4Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (695 aa)
GABRG1Gamma-aminobutyric acid type A receptor gamma1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
KCNQ3Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family. (754 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1986 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
GABRQGamma-aminobutyric acid type A receptor theta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (650 aa)
CLIC3Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (237 aa)
GABRA3Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (492 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1043 aa)
TRPV6Transient receptor potential cation channel subfamily V member 6; Belongs to the transient receptor (TC 1.A.4) family. (728 aa)
TRPV5Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family. (732 aa)
CLCN1Chloride channel protein. (979 aa)
GABRPGamma-aminobutyric acid type A receptor pi subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (440 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1044 aa)
SLC40A1Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (571 aa)
GLRBGlycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (458 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (836 aa)
GABRA4Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (555 aa)
H0X9U7_OTOGAUncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (312 aa)
KCNK9Potassium channel subfamily K member. (378 aa)
SLC9A4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (587 aa)
KCNK7Potassium channel subfamily K member. (307 aa)
ATP6V0A4V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (839 aa)
CNGA2Cyclic nucleotide gated channel subunit alpha 2. (664 aa)
KCNH4Potassium voltage-gated channel subfamily H member 4. (1015 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (372 aa)
KCNK12Potassium two pore domain channel subfamily K member 12; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (430 aa)
PANX2Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (664 aa)
KCNJ8Potassium voltage-gated channel subfamily J member 8. (424 aa)
KCNA4Potassium voltage-gated channel subfamily A member 4; Belongs to the potassium channel family. (654 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (831 aa)
ATP5MC1ATP synthase membrane subunit c locus 1; Belongs to the ATPase C chain family. (147 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (605 aa)
KCNH6Potassium voltage-gated channel subfamily H member 6. (989 aa)
ASIC3Acid sensing ion channel subunit 3; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (534 aa)
KCNA1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
KCNC4Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family. (626 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (388 aa)
BEST1Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (584 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (422 aa)
H0Y230_OTOGAATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (138 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (358 aa)
KCNA3Potassium voltage-gated channel subfamily A member 3; Belongs to the potassium channel family. (488 aa)
KCNG2Potassium voltage-gated channel modifier subfamily G member 2; Belongs to the potassium channel family. (477 aa)
KCNC3Potassium voltage-gated channel subfamily C member 3; Belongs to the potassium channel family. (773 aa)
H0XMA0_OTOGAFXYD domain-containing ion transport regulator; Belongs to the FXYD family. (175 aa)
KCNF1Potassium voltage-gated channel modifier subfamily F member 1; Belongs to the potassium channel family. (494 aa)
KCNQ5Potassium voltage-gated channel, KQT-like subfamily, member 5 (Predicted); Belongs to the potassium channel family. (295 aa)
H0XMV8_OTOGAFXYD domain-containing ion transport regulator; Belongs to the FXYD family. (95 aa)
H0XN94_OTOGAP2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (375 aa)
CLIC5Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (240 aa)
FXYD1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (93 aa)
CLCN4Chloride channel protein. (769 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (237 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1958 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (395 aa)
SLC4A7Anion exchange protein. (1115 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1699 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (870 aa)
ATP5F1CATP synthase subunit gamma. (298 aa)
PANX1Pannexin; Structural component of the gap junctions and the hemichannels. (427 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
FXYD6FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (102 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (428 aa)
GRIK5Glutamate ionotropic receptor kainate type subunit 5. (977 aa)
SLC9A2Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (810 aa)
ASIC2Acid sensing ion channel subunit 2; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (530 aa)
GLRA3Glycine receptor alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (400 aa)
SLC26A1Sulfate anion transporter 1; Mediates sulfate transport with high affinity. Mediates oxalate transport. Mediates bicarbonate transport. Does not accept succinate as cosubstrate; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (705 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1115 aa)
MRS2Magnesium transporter. (443 aa)
ATP2C1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (974 aa)
HTR3C5-hydroxytryptamine receptor 3C; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (848 aa)
ATP5MGATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...] (103 aa)
ATP6V1G3V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2336 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1351 aa)
TTYH1Protein tweety homolog; Probable chloride channel; Belongs to the tweety family. (450 aa)
GABRDGamma-aminobutyric acid type A receptor delta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1248 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1783 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1198 aa)
ATP6V0E1V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
CHRNB3Cholinergic receptor nicotinic beta 3 subunit. (461 aa)
H0XNK0_OTOGASolute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (545 aa)
KCNG1Potassium voltage-gated channel modifier subfamily G member 1; Belongs to the potassium channel family. (514 aa)
CLCN6Chloride voltage-gated channel 6; Belongs to the chloride channel (TC 2.A.49) family. (872 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
KCNJ16Potassium voltage-gated channel subfamily J member 16. (419 aa)
GABRB2Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (433 aa)
H0XPH7_OTOGAFXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
GABRA6Gamma-aminobutyric acid type A receptor alpha6 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (464 aa)
H0XQ52_OTOGAATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...] (103 aa)
H0XQ59_OTOGAATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (131 aa)
KCNS1Potassium voltage-gated channel subfamily S member 1; Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 and KCNB2. Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.1/KCNS1 sub-subfamily. (528 aa)
H0XQK1_OTOGANeur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (101 aa)
KCNA10Potassium voltage-gated channel subfamily A member 10; Belongs to the potassium channel family. (511 aa)
KCNS3Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family. (490 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
CLCN2Chloride channel protein. (906 aa)
SCNM1Sodium channel modifier 1 (Predicted). (230 aa)
CHRNA5Cholinergic receptor nicotinic alpha 5 subunit. (437 aa)
SCARA5Scavenger receptor class A member 5; Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non- transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the de [...] (495 aa)
CNGA3Cyclic nucleotide gated channel subunit alpha 3. (705 aa)
KCNS2Potassium voltage-gated channel modifier subfamily S member 2; Belongs to the potassium channel family. (512 aa)
CNGA1Cyclic nucleotide gated channel subunit alpha 1. (681 aa)
KCNV2Potassium voltage-gated channel modifier subfamily V member 2; Belongs to the potassium channel family. (447 aa)
KCNG3Potassium voltage-gated channel modifier subfamily G member 3; Belongs to the potassium channel family. (436 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (393 aa)
KCNJ4Potassium voltage-gated channel subfamily J member 4. (444 aa)
ATP5MC3ATP synthase membrane subunit c locus 3; Belongs to the ATPase C chain family. (153 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1200 aa)
CHRNA2Cholinergic receptor nicotinic alpha 2 subunit. (531 aa)
CHRNB2Cholinergic receptor nicotinic beta 2 subunit. (502 aa)
H0XUZ7_OTOGASolute carrier organic anion transporter family member. (691 aa)
GABRA2Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (388 aa)
ASIC4Acid sensing ion channel subunit family member 4; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (491 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
PIEZO1Piezo-type mechanosensitive ion channel component. (2785 aa)
KCNA2Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa)
PIEZO2Piezo-type mechanosensitive ion channel component. (2717 aa)
BEST2Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (512 aa)
ATP4ASodium/potassium-transporting ATPase subunit alpha. (1034 aa)
GABRB3Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (434 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
KCNJ1Potassium voltage-gated channel subfamily J member 1. (391 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (222 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (943 aa)
ATP6V1G2V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (158 aa)
KCNK13Potassium two pore domain channel subfamily K member 13; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (408 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (258 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1907 aa)
CLIC1Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (241 aa)
CLIC6Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (585 aa)
KCND1Potassium voltage-gated channel subfamily D member 1; Belongs to the potassium channel family. (645 aa)
CHRNGCholinergic receptor nicotinic gamma subunit. (519 aa)
KCNH8Potassium voltage-gated channel subfamily H member 8. (1107 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (640 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (877 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (810 aa)
SCNN1GSodium channel epithelial 1 gamma subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (652 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
SLC4A3Anion exchange protein. (1007 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (515 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1203 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1023 aa)
KCNJ12Uncharacterized protein. (433 aa)
ATP6V0D1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
SLC9A5Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (897 aa)
TTYH2Protein tweety homolog; Probable chloride channel; Belongs to the tweety family. (534 aa)
SLCO1C1Solute carrier organic anion transporter family member. (729 aa)
KCNJ10Potassium voltage-gated channel subfamily J member 10. (439 aa)
CHRNA1Cholinergic receptor nicotinic alpha 1 subunit. (457 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2323 aa)
KCNA7Potassium voltage-gated channel subfamily A member 7; Belongs to the potassium channel family. (488 aa)
ATP6V0BATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (205 aa)
GRID1Glutamate ionotropic receptor delta type subunit 1. (759 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (675 aa)
GRIK4Glutamate ionotropic receptor kainate type subunit 4. (940 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2499 aa)
GLRA1Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (434 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1468 aa)
SLC4A2Anion exchange protein. (1234 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1874 aa)
ATP5PDATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (161 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
Server load: low (18%) [HD]