STRINGSTRING
ARHGEF40 ARHGEF40 H0WWX9_OTOGA H0WWX9_OTOGA FGD2 FGD2 KXD1 KXD1 ARHGEF39 ARHGEF39 FGD3 FGD3 MAPK8 MAPK8 NGEF NGEF ARHGEF5 ARHGEF5 ARHGEF12 ARHGEF12 ABR ABR HDAC2 HDAC2 SESTD1 SESTD1 ARHGEF26 ARHGEF26 FGD4 FGD4 ARHGEF2 ARHGEF2 TIAM2 TIAM2 PRDM4 PRDM4 RIPK2 RIPK2 NFKB1 NFKB1 CASP2 CASP2 AATF AATF RELA RELA SMPD2 SMPD2 TRIO TRIO SOS2 SOS2 ARHGEF10 ARHGEF10 ARHGEF10L ARHGEF10L BEX3 BEX3 MAPK10 MAPK10 IRAK1 IRAK1 KALRN KALRN ARHGEF3 ARHGEF3 TRAF6 TRAF6 BAD BAD MYD88 MYD88 YWHAE YWHAE CASP3 CASP3 ARHGEF4 ARHGEF4 ITSN1 ITSN1 ARHGEF15 ARHGEF15 PSEN2 PSEN2 VAV3 VAV3 MCF2L MCF2L APH1B APH1B VAV2 VAV2 H0XI83_OTOGA H0XI83_OTOGA UBA52 UBA52 MAG MAG H0XJL7_OTOGA H0XJL7_OTOGA H0XKP4_OTOGA H0XKP4_OTOGA OMG OMG ECT2L ECT2L PLEKHG5 PLEKHG5 FGD1 FGD1 H0XQ16_OTOGA H0XQ16_OTOGA MAGED1 MAGED1 RTN4R RTN4R CCDC71L CCDC71L GNA13 GNA13 H0XUE4_OTOGA H0XUE4_OTOGA BCL2L11 BCL2L11 H0XX44_OTOGA H0XX44_OTOGA LINGO2 LINGO2 H0XY59_OTOGA H0XY59_OTOGA NGF NGF ARHGEF33 ARHGEF33 H0XZG3_OTOGA H0XZG3_OTOGA LINGO1 LINGO1 H0Y1A1_OTOGA H0Y1A1_OTOGA HDAC1 HDAC1 ARHGEF1 ARHGEF1 PRKCI PRKCI IKBKB IKBKB ARHGEF38 ARHGEF38 ARHGEF19 ARHGEF19 LINGO4 LINGO4 ARHGEF16 ARHGEF16 APH1A APH1A ARHGEF9 ARHGEF9 ARHGEF6 ARHGEF6 TGM6 TGM6 PSENEN PSENEN TIAM1 TIAM1 NFKBIA NFKBIA NET1 NET1 ECT2 ECT2 ARHGEF37 ARHGEF37 H0WLC2_OTOGA H0WLC2_OTOGA RASGRF2 RASGRF2 PREX1 PREX1 H0WKN8_OTOGA H0WKN8_OTOGA SOS1 SOS1 SQSTM1 SQSTM1 VAV1 VAV1 ARHGEF7 ARHGEF7 ARHGEF11 ARHGEF11 NCSTN NCSTN MCF2 MCF2 ARHGEF17 ARHGEF17 MCF2L2 MCF2L2 HDAC3 HDAC3 ADAM17 ADAM17 NGFR NGFR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARHGEF40Rho guanine nucleotide exchange factor 40. (1517 aa)
H0WWX9_OTOGAUncharacterized protein. (1089 aa)
FGD2FYVE, RhoGEF and PH domain containing 2. (654 aa)
KXD1KxDL motif containing 1. (123 aa)
ARHGEF39Rho guanine nucleotide exchange factor 39. (323 aa)
FGD3FYVE, RhoGEF and PH domain containing 3. (737 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
NGEFNeuronal guanine nucleotide exchange factor. (620 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5. (1606 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1526 aa)
ABRABR activator of RhoGEF and GTPase. (813 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (422 aa)
SESTD1SEC14 and spectrin domain containing 1. (698 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (874 aa)
FGD4FYVE, RhoGEF and PH domain containing 4. (874 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (987 aa)
TIAM2T cell lymphoma invasion and metastasis 2. (1699 aa)
PRDM4PR domain zinc finger protein 4; May function as a transcription factor involved in cell differentiation. (796 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (539 aa)
NFKB1Nuclear factor kappa B subunit 1. (964 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (452 aa)
AATFApoptosis antagonizing transcription factor. (531 aa)
RELARELA proto-oncogene, NF-kB subunit. (429 aa)
SMPD2Sphingomyelin phosphodiesterase 2. (422 aa)
TRIOTrio Rho guanine nucleotide exchange factor. (3051 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
ARHGEF10Rho guanine nucleotide exchange factor 10. (1329 aa)
ARHGEF10LRho guanine nucleotide exchange factor 10 like. (1279 aa)
BEX3Brain expressed X-linked 3. (112 aa)
MAPK10Mitogen-activated protein kinase. (426 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (710 aa)
KALRNKalirin RhoGEF kinase. (2985 aa)
ARHGEF3Rho guanine nucleotide exchange factor 3. (534 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (535 aa)
BADBCL2 associated agonist of cell death. (168 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (233 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
ARHGEF4Rho guanine nucleotide exchange factor 4. (547 aa)
ITSN1Intersectin 1. (1716 aa)
ARHGEF15Rho guanine nucleotide exchange factor 15. (841 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (451 aa)
VAV3Vav guanine nucleotide exchange factor 3. (624 aa)
MCF2LMCF.2 cell line derived transforming sequence like. (1179 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
VAV2Vav guanine nucleotide exchange factor 2. (713 aa)
H0XI83_OTOGAUbiquitin-like domain-containing protein. (155 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
MAGMyelin associated glycoprotein. (634 aa)
H0XJL7_OTOGAUncharacterized protein. (153 aa)
H0XKP4_OTOGAUncharacterized protein. (369 aa)
OMGOligodendrocyte myelin glycoprotein. (440 aa)
ECT2LEpithelial cell transforming 2 like. (905 aa)
PLEKHG5Pleckstrin homology and RhoGEF domain containing G5. (1078 aa)
FGD1FYVE, RhoGEF and PH domain containing 1. (959 aa)
H0XQ16_OTOGAUncharacterized protein. (816 aa)
MAGED1MAGE family member D1. (782 aa)
RTN4RReticulon 4 receptor. (473 aa)
CCDC71LCoiled-coil domain containing 71 like. (234 aa)
GNA13G protein subunit alpha 13. (379 aa)
H0XUE4_OTOGAUbiquitin-like domain-containing protein. (155 aa)
BCL2L11BCL2 like 11. (200 aa)
H0XX44_OTOGAUbiquitin-like domain-containing protein. (155 aa)
LINGO2Leucine rich repeat and Ig domain containing 2. (606 aa)
H0XY59_OTOGAUncharacterized protein. (129 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (244 aa)
ARHGEF33Rho guanine nucleotide exchange factor 33. (872 aa)
H0XZG3_OTOGAUncharacterized protein. (162 aa)
LINGO1Leucine rich repeat and Ig domain containing 1. (620 aa)
H0Y1A1_OTOGAUncharacterized protein. (195 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (941 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (609 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (729 aa)
ARHGEF38Rho guanine nucleotide exchange factor 38. (687 aa)
ARHGEF19Rho guanine nucleotide exchange factor 19. (806 aa)
LINGO4Leucine rich repeat and Ig domain containing 4. (607 aa)
ARHGEF16Rho guanine nucleotide exchange factor 16. (705 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
ARHGEF9Cdc42 guanine nucleotide exchange factor 9. (523 aa)
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (850 aa)
TGM6Transglutaminase 6. (707 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1495 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
NET1Neuroepithelial cell transforming 1. (600 aa)
ECT2Epithelial cell transforming 2. (916 aa)
ARHGEF37Rho guanine nucleotide exchange factor 37. (661 aa)
H0WLC2_OTOGAReticulon. (648 aa)
RASGRF2Ras protein specific guanine nucleotide releasing factor 2. (1239 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1654 aa)
H0WKN8_OTOGAUncharacterized protein. (1165 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1304 aa)
SQSTM1Sequestosome 1. (446 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (784 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1561 aa)
NCSTNNicastrin. (709 aa)
MCF2MCF.2 cell line derived transforming sequence. (1065 aa)
ARHGEF17Rho guanine nucleotide exchange factor 17. (2063 aa)
MCF2L2MCF.2 cell line derived transforming sequence-like 2. (1035 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (434 aa)
ADAM17ADAM metallopeptidase domain 17. (828 aa)
NGFRNerve growth factor receptor. (430 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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