STRINGSTRING
SOX3 SOX3 WNT1 WNT1 LOC100942189-2 LOC100942189-2 H0XV82_OTOGA H0XV82_OTOGA RUNX3 RUNX3 H0XVD2_OTOGA H0XVD2_OTOGA LOC100962662-2 LOC100962662-2 LOC100944801 LOC100944801 LOC100966022 LOC100966022 LOC100963051 LOC100963051 SOX4 SOX4 LOC105888222-5 LOC105888222-5 LOC100953470 LOC100953470 H0XX44_OTOGA H0XX44_OTOGA FZD8 FZD8 H0XX75_OTOGA H0XX75_OTOGA PSME1 PSME1 RSPO4 RSPO4 BTBD18 BTBD18 H0XYF5_OTOGA H0XYF5_OTOGA H0XYI8_OTOGA H0XYI8_OTOGA H0XYI9_OTOGA H0XYI9_OTOGA H2AC6 H2AC6 DVL1 DVL1 H0XZ35_OTOGA H0XZ35_OTOGA H2BC14 H2BC14 PSME2 PSME2 LOC100946065 LOC100946065 TCF7 TCF7 FRAT1 FRAT1 SLC39A13 SLC39A13 CBY1 CBY1 CXXC4 CXXC4 PSMA4 PSMA4 PSME4 PSME4 CSNK2B CSNK2B WNT4 WNT4 PSMC6 PSMC6 PSMD5 PSMD5 PPP2CA PPP2CA TLE4 TLE4 PSMB6 PSMB6 PIP5K1B PIP5K1B PSME3 PSME3 SOX30 SOX30 PPP2R5A PPP2R5A KREMEN1 KREMEN1 PSMB3 PSMB3 RSPO1 RSPO1 KREMEN2 KREMEN2 AXIN2 AXIN2 PSMA6 PSMA6 PSMC5 PSMC5 SOX15 SOX15 WIF1 WIF1 H4C8 H4C8 LOC100958063 LOC100958063 LOC105888222-2 LOC105888222-2 LOC100942189 LOC100942189 H0WXI2_OTOGA H0WXI2_OTOGA LOC100940363 LOC100940363 H2BC5 H2BC5 LOC100941637 LOC100941637 LOC100942503 LOC100942503 LOC105888222 LOC105888222 H0WXD6_OTOGA H0WXD6_OTOGA LRP6 LRP6 LRP5 LRP5 WNT5A WNT5A SOST SOST KXD1 KXD1 RBBP5 RBBP5 TNKS TNKS PSMC4 PSMC4 H0WUK3_OTOGA H0WUK3_OTOGA PSMD10 PSMD10 CTBP1 CTBP1 PPP2R5C PPP2R5C H2AC20 H2AC20 H2BC21 H2BC21 LOC100959075 LOC100959075 WNT3 WNT3 GSK3B GSK3B LOC100945040 LOC100945040 PPP2R5E PPP2R5E HDAC1 HDAC1 MYC MYC SOX6 SOX6 PSMC2 PSMC2 PSMB5 PSMB5 PSMD14 PSMD14 RNF43 RNF43 TLE3 TLE3 HMGXB3 HMGXB3 DVL2 DVL2 LEF1 LEF1 DKK1 DKK1 PSMD8 PSMD8 PSMB4 PSMB4 BCL9 BCL9 PSMB7 PSMB7 H2AZ1 H2AZ1 CSNK2A2 CSNK2A2 H0WME2_OTOGA H0WME2_OTOGA PSMD13 PSMD13 PYGO1 PYGO1 PSMD4 PSMD4 CHD8 CHD8 H0WLB6_OTOGA H0WLB6_OTOGA SOX5 SOX5 PPP2CB PPP2CB CREBBP CREBBP FZD6 FZD6 LEO1 LEO1 H0WKA6_OTOGA H0WKA6_OTOGA PSMB2 PSMB2 LGR6 LGR6 FZD2 FZD2 CSNK1E CSNK1E TCF7L1 TCF7L1 PSMA7 PSMA7 LRTM1 LRTM1 TRRAP TRRAP EP300 EP300 PSMA3 PSMA3 CDC73 CDC73 RYK RYK DKK2 DKK2 XPO1 XPO1 FZD5 FZD5 WNT8B WNT8B SOX7 SOX7 LOC105888222-6 LOC105888222-6 LY6G5B LY6G5B LOC100942503-11 LOC100942503-11 SOX2 SOX2 SOX9 SOX9 LGR5 LGR5 PSMB11 PSMB11 PSMD7 PSMD7 AXIN1 AXIN1 PPP2R5B PPP2R5B ASH2L ASH2L PSMD6 PSMD6 PSMD2 PSMD2 H0XCY9_OTOGA H0XCY9_OTOGA SMURF2 SMURF2 PSMD11 PSMD11 PSMB10 PSMB10 ZBTB44 ZBTB44 DVL3 DVL3 TLE2 TLE2 DKK4 DKK4 CTNNB1 CTNNB1 LOC100940682 LOC100940682 LOC100942503-4 LOC100942503-4 LOC100942503-5 LOC100942503-5 H0XBX0_OTOGA H0XBX0_OTOGA BTRC BTRC PSMF1 PSMF1 RSPO3 RSPO3 TCF7L2 TCF7L2 CAV1 CAV1 KAT5 KAT5 RUVBL1 RUVBL1 AKT2 AKT2 CCDC88C CCDC88C PSMB9 PSMB9 PSMB8 PSMB8 PSMA5 PSMA5 PPP2R1A PPP2R1A WNT3A WNT3A WNT9A WNT9A KMT2D KMT2D LOC105888222-3 LOC105888222-3 LOC100963968 LOC100963968 PSMA2 PSMA2 RBX1 RBX1 SOX11 SOX11 SFRP5 SFRP5 LOC100962662 LOC100962662 APC2 APC2 PYGO2 PYGO2 H0XI59_OTOGA H0XI59_OTOGA LOC100942503-6 LOC100942503-6 H0XI75_OTOGA H0XI75_OTOGA H0XI83_OTOGA H0XI83_OTOGA UBA52 UBA52 H0XIX9_OTOGA H0XIX9_OTOGA LOC100957578 LOC100957578 H0XJC9_OTOGA H0XJC9_OTOGA HMGXB4 HMGXB4 H0XJL7_OTOGA H0XJL7_OTOGA TNKS2 TNKS2 HECW1 HECW1 LGR4 LGR4 USP34 USP34 TLE1 TLE1 PPP2R5D PPP2R5D PPP2R1B PPP2R1B AMER1 AMER1 USP8 USP8 PSMD1 PSMD1 CUL3 CUL3 SFRP2 SFRP2 SOX13 SOX13 PSMA1 PSMA1 H0X541_OTOGA H0X541_OTOGA FZD4 FZD4 PSMD12 PSMD12 PSMB1 PSMB1 PSMA8 PSMA8 PSMD3 PSMD3 H0XKS4_OTOGA H0XKS4_OTOGA SOX12 SOX12 H0XL03_OTOGA H0XL03_OTOGA LOC105888222-4 LOC105888222-4 CTNNBIP1 CTNNBIP1 H0XLJ0_OTOGA H0XLJ0_OTOGA H0XLK2_OTOGA H0XLK2_OTOGA LOC100958180 LOC100958180 SOX17 SOX17 SOX1 SOX1 BCL9L BCL9L TERT TERT H0XN06_OTOGA H0XN06_OTOGA LOC100945692 LOC100945692 APC APC SMARCA4 SMARCA4 LOC100942503-8 LOC100942503-8 H2BC1 H2BC1 LOC100961925 LOC100961925 H0XP74_OTOGA H0XP74_OTOGA SOX8 SOX8 ZNRF3 ZNRF3 AKT1 AKT1 H2BC11 H2BC11 H0XPX5_OTOGA H0XPX5_OTOGA LOC100941637-2 LOC100941637-2 WNT8A WNT8A LOC100957578-2 LOC100957578-2 H2AX H2AX LOC100942503-9 LOC100942503-9 H0XR91_OTOGA H0XR91_OTOGA DACT1 DACT1 H0XRI3_OTOGA H0XRI3_OTOGA H0XRN2_OTOGA H0XRN2_OTOGA CSNK1G2 CSNK1G2 SOX21 SOX21 FRAT2 FRAT2 H0XSF2_OTOGA H0XSF2_OTOGA H0XSP9_OTOGA H0XSP9_OTOGA H2AZ2 H2AZ2 LOC100944154 LOC100944154 RSPO2 RSPO2 H0XTG3_OTOGA H0XTG3_OTOGA LOC100945989 LOC100945989 MEN1 MEN1 LOC100944085 LOC100944085 SFRP1 SFRP1 H0XUE4_OTOGA H0XUE4_OTOGA PSMD9 PSMD9 SOX18 SOX18 DACT3 DACT3 H0XUT0_OTOGA H0XUT0_OTOGA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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SOX3SRY-box transcription factor 3. (332 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
LOC100942189-2Histone H2A type 1-B/E. (130 aa)
H0XV82_OTOGAHistone domain-containing protein. (84 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (459 aa)
H0XVD2_OTOGAANK_REP_REGION domain-containing protein. (226 aa)
LOC100962662-2Histone H3. (136 aa)
LOC100944801AAA domain-containing protein; Belongs to the AAA ATPase family. (441 aa)
LOC100966022Histone domain-containing protein; Belongs to the histone H2B family. (126 aa)
LOC100963051Protein kinase domain-containing protein. (327 aa)
SOX4Transcription factor SOX. (476 aa)
LOC105888222-5Histone H3.1. (136 aa)
LOC10095347014_3_3 domain-containing protein; Belongs to the 14-3-3 family. (247 aa)
H0XX44_OTOGAUbiquitin-like domain-containing protein. (155 aa)
FZD8Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (513 aa)
H0XX75_OTOGAPROTEASOME_ALPHA_1 domain-containing protein. (231 aa)
PSME1Proteasome activator subunit 1. (249 aa)
RSPO4R-spondin 4. (202 aa)
BTBD18BTB domain-containing protein. (711 aa)
H0XYF5_OTOGA14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (165 aa)
H0XYI8_OTOGAProteasome subunit alpha type. (234 aa)
H0XYI9_OTOGAWD_REPEATS_REGION domain-containing protein. (308 aa)
H2AC6Histone H2A; Belongs to the histone H2A family. (130 aa)
DVL1Dishevelled segment polarity protein 1. (696 aa)
H0XZ35_OTOGAHistone domain-containing protein; Belongs to the histone H2B family. (165 aa)
H2BC14Histone H2B; Belongs to the histone H2B family. (126 aa)
PSME2Uncharacterized protein. (239 aa)
LOC100946065Histone H3.3. (136 aa)
TCF7Transcription factor 7. (419 aa)
FRAT1FRAT regulator of WNT signaling pathway 1. (277 aa)
SLC39A13Solute carrier family 39 member 13. (421 aa)
CBY1Chibby family member 1, beta catenin antagonist. (127 aa)
CXXC4CXXC finger protein 4. (225 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSME4Proteasome activator subunit 4. (1840 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (333 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
PSMD5Uncharacterized protein. (504 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
TLE4TLE family member 4, transcriptional corepressor. (774 aa)
PSMB6Proteasome subunit beta. (239 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (500 aa)
PSME3Proteasome activator subunit 3. (254 aa)
SOX30SRY-box transcription factor 30. (768 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
KREMEN1Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (492 aa)
PSMB3Proteasome subunit beta. (210 aa)
RSPO1R-spondin 1. (263 aa)
KREMEN2Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (461 aa)
AXIN2Axin 2. (844 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
SOX15SRY-box transcription factor 15. (229 aa)
WIF1WNT inhibitory factor 1. (381 aa)
H4C8Histone H4. (103 aa)
LOC100958063Histone H3.1. (136 aa)
LOC105888222-2Histone H3.1. (136 aa)
LOC100942189Histone H2A; Belongs to the histone H2A family. (130 aa)
H0WXI2_OTOGAHistone H2B; Belongs to the histone H2B family. (135 aa)
LOC100940363Histone H2A; Belongs to the histone H2A family. (130 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC100941637Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC100942503Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC105888222Histone H3.1. (136 aa)
H0WXD6_OTOGAHistone H3; Belongs to the histone H3 family. (136 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1615 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1595 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
SOSTSclerostin. (213 aa)
KXD1KxDL motif containing 1. (123 aa)
RBBP5RB binding protein 5, histone lysine methyltransferase complex subunit. (538 aa)
TNKSPoly [ADP-ribose] polymerase. (1326 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
H0WUK3_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (364 aa)
PSMD10ANK_REP_REGION domain-containing protein. (223 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (430 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (493 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
H2BC21Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC100959075Histone H3; Belongs to the histone H3 family. (136 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
GSK3BGlycogen synthase kinase 3 beta. (387 aa)
LOC100945040Histone H3; Belongs to the histone H3 family. (136 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (424 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (452 aa)
SOX6SRY-box transcription factor 6. (828 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (434 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (308 aa)
RNF43RING-type domain-containing protein. (782 aa)
TLE3TLE family member 3, transcriptional corepressor. (775 aa)
HMGXB3HMG-box containing 3. (1288 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
LEF1Lymphoid enhancer binding factor 1. (398 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (268 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
BCL9BCL9 transcription coactivator. (1426 aa)
PSMB7Proteasome subunit beta. (277 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa)
H0WME2_OTOGAProtein kinase domain-containing protein. (236 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
PYGO1Pygopus family PHD finger 1. (419 aa)
PSMD4Proteasome 26S non-ATPase subunit 4 (Predicted). (427 aa)
CHD8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2584 aa)
H0WLB6_OTOGAProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
SOX5SRY-box transcription factor 5. (763 aa)
PPP2CBSerine/threonine-protein phosphatase. (308 aa)
CREBBPCREB binding protein. (2443 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (667 aa)
H0WKA6_OTOGAUncharacterized protein. (354 aa)
PSMB2Proteasome subunit beta. (202 aa)
LGR6Leucine rich repeat containing G protein-coupled receptor 6. (965 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (588 aa)
CSNK1EProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa)
TCF7L1Transcription factor 7 like 1. (574 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
LRTM1Leucine rich repeats and transmembrane domains 1. (343 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3860 aa)
EP300E1A binding protein p300. (2420 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
CDC73Cell division cycle 73. (531 aa)
RYKReceptor like tyrosine kinase. (537 aa)
DKK2Dickkopf WNT signaling pathway inhibitor 2. (258 aa)
XPO1Exportin 1. (1048 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
SOX7SRY-box transcription factor 7. (386 aa)
LOC105888222-6Histone H3.1. (136 aa)
LY6G5BLymphocyte antigen 6 family member G5B. (195 aa)
LOC100942503-11Histone H4. (103 aa)
SOX2SRY-box transcription factor 2. (319 aa)
SOX9SRY-box transcription factor 9. (568 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (764 aa)
PSMB11Proteasome subunit beta. (300 aa)
PSMD7MPN domain-containing protein. (324 aa)
AXIN1Axin 1. (867 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
ASH2LASH2 like, histone lysine methyltransferase complex subunit. (625 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
H0XCY9_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (466 aa)
SMURF2E3 ubiquitin-protein ligase. (732 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (430 aa)
PSMB10Proteasome subunit beta. (273 aa)
ZBTB44Zinc finger and BTB domain containing 44. (595 aa)
DVL3Dishevelled segment polarity protein 3. (722 aa)
TLE2TLE family member 2, transcriptional corepressor. (756 aa)
DKK4Dickkopf WNT signaling pathway inhibitor 4. (218 aa)
CTNNB1Catenin beta 1. (781 aa)
LOC100940682Histone H2B type 1. (126 aa)
LOC100942503-4Histone H4. (103 aa)
LOC100942503-5Histone H4. (103 aa)
H0XBX0_OTOGABTB domain-containing protein. (261 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (526 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
RSPO3R-spondin 3. (211 aa)
TCF7L2Transcription factor 7 like 2. (471 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (458 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
CCDC88CCoiled-coil domain containing 88C. (2024 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMB8Proteasome subunit beta. (276 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (591 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
KMT2DLysine methyltransferase 2D. (5528 aa)
LOC105888222-3Histone H3.1. (136 aa)
LOC100963968Uncharacterized protein. (244 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
RBX1Ring-box 1. (108 aa)
SOX11Transcription factor SOX. (421 aa)
SFRP5Secreted frizzled related protein 5. (315 aa)
LOC100962662Histone H3. (136 aa)
APC2APC regulator of WNT signaling pathway 2. (2292 aa)
PYGO2Pygopus family PHD finger 2. (406 aa)
H0XI59_OTOGA14_3_3 domain-containing protein. (62 aa)
LOC100942503-6Histone H4. (103 aa)
H0XI75_OTOGAJAB_MPN domain-containing protein. (295 aa)
H0XI83_OTOGAUbiquitin-like domain-containing protein. (155 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
H0XIX9_OTOGAHistone H3; Belongs to the histone H3 family. (136 aa)
LOC100957578Histone H2B type 2-E. (126 aa)
H0XJC9_OTOGAUncharacterized protein. (287 aa)
HMGXB4HMG-box containing 4. (492 aa)
H0XJL7_OTOGAUncharacterized protein. (153 aa)
TNKS2Poly [ADP-ribose] polymerase. (1169 aa)
HECW1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1573 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (1036 aa)
USP34Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family. (3532 aa)
TLE1TLE family member 1, transcriptional corepressor. (780 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (602 aa)
AMER1APC membrane recruitment protein 1. (749 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1117 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
CUL3Cullin 3; Belongs to the cullin family. (746 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
SOX13SRY-box transcription factor 13. (581 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
H0X541_OTOGAProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (426 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (467 aa)
PSMB1Proteasome subunit beta. (235 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (536 aa)
H0XKS4_OTOGAUncharacterized protein. (354 aa)
SOX12Transcription factor SOX. (314 aa)
H0XL03_OTOGAWD_REPEATS_REGION domain-containing protein. (237 aa)
LOC105888222-4Histone H3.1. (136 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
H0XLJ0_OTOGAHistone domain-containing protein; Belongs to the histone H2B family. (122 aa)
H0XLK2_OTOGAUncharacterized protein. (247 aa)
LOC100958180Histone H3; Belongs to the histone H3 family. (136 aa)
SOX17SRY-box transcription factor 17. (307 aa)
SOX1SRY-box transcription factor 1. (365 aa)
BCL9LBCL9 like. (1497 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1131 aa)
H0XN06_OTOGAProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (364 aa)
LOC100945692Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
APCAPC regulator of WNT signaling pathway. (2812 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1505 aa)
LOC100942503-8Histone H4. (103 aa)
H2BC1Histone H2B; Belongs to the histone H2B family. (136 aa)
LOC100961925Histone H2B; Belongs to the histone H2B family. (126 aa)
H0XP74_OTOGAProtein kinase domain-containing protein. (348 aa)
SOX8SRY-box transcription factor 8. (463 aa)
ZNRF3Zinc and ring finger 3. (836 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (126 aa)
H0XPX5_OTOGAHistone domain-containing protein; Belongs to the histone H2B family. (141 aa)
LOC100941637-2Histone H2B type 1. (126 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
LOC100957578-2Histone H2B type 2-E. (126 aa)
H2AXHistone H2A; Belongs to the histone H2A family. (143 aa)
LOC100942503-9Histone H4. (103 aa)
H0XR91_OTOGAHistone domain-containing protein; Belongs to the histone H2B family. (169 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (824 aa)
H0XRI3_OTOGAAAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
H0XRN2_OTOGAUncharacterized protein. (198 aa)
CSNK1G2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (417 aa)
SOX21SRY-box transcription factor 21. (275 aa)
FRAT2FRAT regulator of WNT signaling pathway 2. (226 aa)
H0XSF2_OTOGARING-type domain-containing protein. (236 aa)
H0XSP9_OTOGAHistone domain-containing protein; Belongs to the histone H2B family. (121 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (127 aa)
LOC100944154Histone H2B; Belongs to the histone H2B family. (126 aa)
RSPO2R-spondin 2. (204 aa)
H0XTG3_OTOGAHistone domain-containing protein. (135 aa)
LOC100945989Histone H2B; Belongs to the histone H2B family. (135 aa)
MEN1Menin 1. (607 aa)
LOC100944085Histone H2B; Belongs to the histone H2B family. (137 aa)
SFRP1Secreted frizzled related protein 1. (318 aa)
H0XUE4_OTOGAUbiquitin-like domain-containing protein. (155 aa)
PSMD9PDZ domain-containing protein. (223 aa)
SOX18SRY-box transcription factor 18. (387 aa)
DACT3Dishevelled binding antagonist of beta catenin 3. (632 aa)
H0XUT0_OTOGAAAA domain-containing protein. (392 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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