STRINGSTRING
GNPTAB GNPTAB YWHAB YWHAB MOB1B MOB1B NPHP4 NPHP4 STK4 STK4 WWC1 WWC1 YWHAE YWHAE CASP3 CASP3 AMOTL2 AMOTL2 H0Y264_OTOGA H0Y264_OTOGA WWTR1 WWTR1 SAV1 SAV1 H0XZI5_OTOGA H0XZI5_OTOGA H0XV34_OTOGA H0XV34_OTOGA H0XLI4_OTOGA H0XLI4_OTOGA TJP3 TJP3 STK3 STK3 H0XBW6_OTOGA H0XBW6_OTOGA LATS1 LATS1 AMOT AMOT LATS2 LATS2 TJP1 TJP1 DVL2 DVL2 AMOTL1 AMOTL1 H0WMW6_OTOGA H0WMW6_OTOGA YAP1 YAP1 TMEM198 TMEM198
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNPTABN-acetylglucosamine-1-phosphate transferase subunits alpha and beta. (1252 aa)
YWHAB14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (246 aa)
MOB1BMOB kinase activator 1B. (221 aa)
NPHP4Nephrocystin 4. (1429 aa)
STK4Serine/threonine-protein kinase 4 18kDa subunit; Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regul [...] (487 aa)
WWC1WW and C2 domain containing 1. (1180 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (233 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
AMOTL2Angiomotin like 2. (834 aa)
H0Y264_OTOGAUncharacterized protein. (191 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
SAV1Salvador family WW domain containing protein 1. (385 aa)
H0XZI5_OTOGA14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (246 aa)
H0XV34_OTOGADUF4203 domain-containing protein. (310 aa)
H0XLI4_OTOGAUncharacterized protein. (186 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (921 aa)
STK3Serine/threonine kinase 3. (450 aa)
H0XBW6_OTOGAUncharacterized protein; Belongs to the MAGUK family. (1221 aa)
LATS1Large tumor suppressor kinase 1. (1133 aa)
AMOTAngiomotin. (1073 aa)
LATS2Non-specific serine/threonine protein kinase. (1071 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1741 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
AMOTL1Angiomotin like 1. (936 aa)
H0WMW6_OTOGAUncharacterized protein. (212 aa)
YAP1Yes associated protein 1. (501 aa)
TMEM198Transmembrane protein 198 (Predicted). (360 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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