STRINGSTRING
HES5 HES5 HEY1 HEY1 TBL1XR1 TBL1XR1 CDK8 CDK8 HDAC1 HDAC1 HDAC7 HDAC7 HDAC6 HDAC6 MYC MYC NBEA NBEA TLE3 TLE3 HDAC4 HDAC4 HDAC10 HDAC10 CUL1 CUL1 HIF1A HIF1A TLE2 TLE2 KAT2B KAT2B RBX1 RBX1 SKP1 SKP1 H0XPV2_OTOGA H0XPV2_OTOGA MAML1 MAML1 SNW1 SNW1 NCOR1 NCOR1 RBPJ RBPJ HDAC9 HDAC9 HEYL HEYL HEY2 HEY2 HES1 HES1 HDAC11 HDAC11 CCNC CCNC NCOR2 NCOR2 HDAC3 HDAC3 EP300 EP300 MAML2 MAML2 MAMLD1 MAMLD1 TLE1 TLE1 FBXW7 FBXW7 HDAC8 HDAC8 H0X4Q8_OTOGA H0X4Q8_OTOGA HDAC2 HDAC2 HDAC5 HDAC5 TLE4 TLE4 KAT2A KAT2A H0XAK4_OTOGA H0XAK4_OTOGA CREBBP CREBBP H0WMD7_OTOGA H0WMD7_OTOGA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HES5Hes family bHLH transcription factor 5. (159 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
TBL1XR1Transducin beta like 1 X-linked receptor 1. (509 aa)
CDK8Cyclin dependent kinase 8. (407 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (940 aa)
HDAC6Histone deacetylase 6. (1210 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (452 aa)
NBEANeurobeachin. (2799 aa)
TLE3TLE family member 3, transcriptional corepressor. (775 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1043 aa)
HDAC10Histone deacetylase 10. (663 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (827 aa)
TLE2TLE family member 2, transcriptional corepressor. (756 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (793 aa)
RBX1Ring-box 1. (108 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
H0XPV2_OTOGADUF4704 domain-containing protein. (811 aa)
MAML1Mastermind like transcriptional coactivator 1. (1012 aa)
SNW1SNW domain containing 1. (536 aa)
NCOR1Nuclear receptor corepressor 1. (2435 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (486 aa)
HDAC9Histone deacetylase 9. (733 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
HDAC11Histone deacetylase 11. (345 aa)
CCNCCyclin C; Belongs to the cyclin family. (283 aa)
NCOR2Nuclear receptor corepressor 2. (2511 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (434 aa)
EP300E1A binding protein p300. (2420 aa)
MAML2Mastermind like transcriptional coactivator 2. (1113 aa)
MAMLD1Mastermind like domain containing 1. (744 aa)
TLE1TLE family member 1, transcriptional corepressor. (780 aa)
FBXW7F-box and WD repeat domain containing 7. (379 aa)
HDAC8Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (377 aa)
H0X4Q8_OTOGAUncharacterized protein. (575 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (422 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1122 aa)
TLE4TLE family member 4, transcriptional corepressor. (774 aa)
KAT2ALysine acetyltransferase 2A. (838 aa)
H0XAK4_OTOGAUncharacterized protein. (356 aa)
CREBBPCREB binding protein. (2443 aa)
H0WMD7_OTOGAUncharacterized protein. (1504 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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