STRINGSTRING
TUBA1A TUBA1A CXorf38 CXorf38 RILPL1 RILPL1 CTSC CTSC TTC19 TTC19 SEC31B SEC31B LGMN LGMN LOC100957736 LOC100957736 HLA-DRA HLA-DRA DCTN3 DCTN3 RAB7A RAB7A H0WWE9_OTOGA H0WWE9_OTOGA KIF2C KIF2C HLA-DPA1 HLA-DPA1 ACTR1B ACTR1B DYNC1H1 DYNC1H1 CTSH CTSH HLA-DMA HLA-DMA TUBA8 TUBA8 TUBB4B TUBB4B AP2B1 AP2B1 HLA-DQB1 HLA-DQB1 DCTN5 DCTN5 KIF3B KIF3B KIF5A KIF5A DCTN2 DCTN2 KIF15 KIF15 SAR1A SAR1A CST8 CST8 CST11 CST11 CSTL1 CSTL1 CTSA CTSA ACTR1A ACTR1A RACGAP1 RACGAP1 DYNC1I1 DYNC1I1 CD74 CD74 SEC23A SEC23A SEC23B SEC23B CTSK CTSK CTSO CTSO DCTN6 DCTN6 H0WMX7_OTOGA H0WMX7_OTOGA DNM1 DNM1 TUBAL3 TUBAL3 KIF20A KIF20A AP1G1 AP1G1 KLC2 KLC2 CTSF CTSF SEC31A SEC31A CTSD CTSD AP2A2 AP2A2 H0WIE5_OTOGA H0WIE5_OTOGA AP1S1 AP1S1 SEC24D SEC24D H0WGL7_OTOGA H0WGL7_OTOGA DYNC1I2 DYNC1I2 ACTR10 ACTR10 KIF22 KIF22 MIEF1 MIEF1 H0Y2E5_OTOGA H0Y2E5_OTOGA CTSE CTSE TUBB2B TUBB2B CAPZB CAPZB KIF23 KIF23 DYNLL1 DYNLL1 H0XXH4_OTOGA H0XXH4_OTOGA AP2S1 AP2S1 IFI30 IFI30 H0XWV7_OTOGA H0XWV7_OTOGA KLC3 KLC3 AP1B1 AP1B1 H0XWL3_OTOGA H0XWL3_OTOGA KIF26A KIF26A H0XV43_OTOGA H0XV43_OTOGA CPVL CPVL TUBA4A TUBA4A H0XU80_OTOGA H0XU80_OTOGA H0XTR5_OTOGA H0XTR5_OTOGA KIF3C KIF3C DYNLL2 DYNLL2 ENSOGAP00000018960 ENSOGAP00000018960 IGFLR1 IGFLR1 APPBP2 APPBP2 H0XR68_OTOGA H0XR68_OTOGA H0XR11_OTOGA H0XR11_OTOGA H0XQI6_OTOGA H0XQI6_OTOGA H0XPM2_OTOGA H0XPM2_OTOGA H0XPH8_OTOGA H0XPH8_OTOGA TUBB6 TUBB6 H0XN74_OTOGA H0XN74_OTOGA CLTA CLTA AP2M1 AP2M1 TUBB TUBB H0XK92_OTOGA H0XK92_OTOGA TUBB4A TUBB4A CFAP97 CFAP97 H0XHF1_OTOGA H0XHF1_OTOGA H0XH26_OTOGA H0XH26_OTOGA KIF18A KIF18A SEC13 SEC13 KIF5B KIF5B AP2A1 AP2A1 DYNC1LI1 DYNC1LI1 H0XEQ5_OTOGA H0XEQ5_OTOGA AP1M1 AP1M1 OSBPL1A OSBPL1A CTSB CTSB CANX CANX TUBE1 TUBE1 SPTBN2 SPTBN2 KIF3A KIF3A KLC1 KLC1 AP1S3 AP1S3 H0XCS1_OTOGA H0XCS1_OTOGA CTSS CTSS HLA-DOA HLA-DOA AP1M2 AP1M2 CAPZA1 CAPZA1 SH3GL2 SH3GL2 KIF2B KIF2B LOC100947302 LOC100947302 FNDC7 FNDC7 TUBB1 TUBB1 SEC24A SEC24A SAR1B SAR1B DYNC1LI2 DYNC1LI2 H0X8B5_OTOGA H0X8B5_OTOGA ACTRT3 ACTRT3 KLC4 KLC4 CAPZA2 CAPZA2 CLGN CLGN FAM193A FAM193A ST18 ST18 KIF4A KIF4A DNM3 DNM3 MYT1 MYT1 AP1S2 AP1S2 FAM193B FAM193B DCTN4 DCTN4 DNM2 DNM2 ARF1 ARF1 MYT1L MYT1L H0X251_OTOGA H0X251_OTOGA KIFAP3 KIFAP3 SEC24B SEC24B LOC100954785 LOC100954785 H0X155_OTOGA H0X155_OTOGA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TUBA1ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
CXorf38Chromosome X open reading frame 38. (320 aa)
RILPL1Rab interacting lysosomal protein like 1. (405 aa)
CTSCCathepsin C; Belongs to the peptidase C1 family. (463 aa)
TTC19Tetratricopeptide repeat domain 19. (495 aa)
SEC31BSEC31 homolog B, COPII coat complex component. (1179 aa)
LGMNLegumain. (433 aa)
LOC100957736Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (262 aa)
DCTN3Dynactin subunit 3. (186 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
H0WWE9_OTOGATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (721 aa)
HLA-DPA1Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (266 aa)
ACTR1BActin related protein 1B. (376 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4646 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (337 aa)
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (261 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
AP2B1Adaptor related protein complex 2 subunit beta 1. (951 aa)
HLA-DQB1Major histocompatibility complex, class II, DQ beta 1. (276 aa)
DCTN5Dynactin subunit 5. (182 aa)
KIF3BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (757 aa)
KIF5AKinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1032 aa)
DCTN2Dynactin subunit 2. (402 aa)
KIF15Kinesin family member 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1389 aa)
SAR1ASecretion associated Ras related GTPase 1A; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
CST8Cystatin 8. (142 aa)
CST11Cystatin 11. (138 aa)
CSTL1Cystatin like 1. (137 aa)
CTSACarboxypeptidase; Belongs to the peptidase S10 family. (474 aa)
ACTR1AActin related protein 1A. (376 aa)
RACGAP1Rac GTPase activating protein 1. (469 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (468 aa)
CD74CD74 molecule. (282 aa)
SEC23AProtein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (769 aa)
SEC23BProtein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (712 aa)
CTSKCathepsin K; Belongs to the peptidase C1 family. (329 aa)
CTSOCathepsin O; Belongs to the peptidase C1 family. (320 aa)
DCTN6Dynactin subunit 6. (190 aa)
H0WMX7_OTOGACAP-Gly domain-containing protein. (1281 aa)
DNM1Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (851 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
KIF20AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (888 aa)
AP1G1AP-1 complex subunit gamma. (823 aa)
KLC2Kinesin light chain 2. (618 aa)
CTSFCathepsin F; Belongs to the peptidase C1 family. (460 aa)
SEC31ASEC31 homolog A, COPII coat complex component. (1246 aa)
CTSDPeptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (405 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (930 aa)
H0WIE5_OTOGAUncharacterized protein; Belongs to the peptidase C1 family. (334 aa)
AP1S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (177 aa)
SEC24DSEC24 homolog D, COPII coat complex component. (1033 aa)
H0WGL7_OTOGAKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (725 aa)
DYNC1I2Dynein cytoplasmic 1 intermediate chain 2. (618 aa)
ACTR10Uncharacterized protein; Belongs to the actin family. (417 aa)
KIF22Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (645 aa)
MIEF1Mitochondrial elongation factor 1. (463 aa)
H0Y2E5_OTOGAIg-like domain-containing protein. (268 aa)
CTSECathepsin E; Belongs to the peptidase A1 family. (404 aa)
TUBB2BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (272 aa)
KIF23Kinesin family member 23; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (957 aa)
DYNLL1Dynein light chain. (89 aa)
H0XXH4_OTOGAUncharacterized protein. (522 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
IFI30IFI30 lysosomal thiol reductase. (244 aa)
H0XWV7_OTOGATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (352 aa)
KLC3Kinesin light chain 3. (506 aa)
AP1B1AP complex subunit beta. (947 aa)
H0XWL3_OTOGAPept_C1 domain-containing protein; Belongs to the peptidase C1 family. (241 aa)
KIF26AKinesin family member 26A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1860 aa)
H0XV43_OTOGAUncharacterized protein; Belongs to the actin family. (416 aa)
CPVLCarboxypeptidase vitellogenic like; Belongs to the peptidase S10 family. (447 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
H0XU80_OTOGATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa)
H0XTR5_OTOGATubulin domain-containing protein. (99 aa)
KIF3CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (793 aa)
DYNLL2Dynein light chain. (89 aa)
ENSOGAP00000018960annotation not available (189 aa)
IGFLR1IGF like family receptor 1. (349 aa)
APPBP2Amyloid beta precursor protein binding protein 2. (585 aa)
H0XR68_OTOGAKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (817 aa)
H0XR11_OTOGAUncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
H0XQI6_OTOGAAP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa)
H0XPM2_OTOGAUncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (181 aa)
H0XPH8_OTOGAUncharacterized protein; Belongs to the tubulin family. (242 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
H0XN74_OTOGATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (217 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (437 aa)
TUBBTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
H0XK92_OTOGATubulin domain-containing protein; Belongs to the tubulin family. (230 aa)
TUBB4ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
CFAP97Uncharacterized protein. (520 aa)
H0XHF1_OTOGATubulin_C domain-containing protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (305 aa)
H0XH26_OTOGAUncharacterized protein. (1042 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (898 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (356 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (946 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (519 aa)
H0XEQ5_OTOGAMHC_II_beta domain-containing protein. (79 aa)
AP1M1AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (423 aa)
OSBPL1AOxysterol-binding protein; Belongs to the OSBP family. (911 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (339 aa)
CANXCalnexin. (592 aa)
TUBE1Tubulin epsilon 1; Belongs to the tubulin family. (474 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2389 aa)
KIF3AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (696 aa)
KLC1Kinesin light chain 1. (594 aa)
AP1S3AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa)
H0XCS1_OTOGAKinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1056 aa)
CTSSCathepsin S; Belongs to the peptidase C1 family. (331 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (255 aa)
AP1M2AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (423 aa)
CAPZA1F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (277 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (352 aa)
KIF2BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (668 aa)
LOC100947302Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
FNDC7Fibronectin type III domain containing 7. (733 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (453 aa)
SEC24ASEC24 homolog A, COPII coat complex component. (1093 aa)
SAR1BSecretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family. (179 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (498 aa)
H0X8B5_OTOGAMHC_II_beta domain-containing protein. (89 aa)
ACTRT3Actin related protein T3; Belongs to the actin family. (372 aa)
KLC4Kinesin light chain 4. (614 aa)
CAPZA2F-actin-capping protein subunit alpha-2; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (286 aa)
CLGNCalmegin. (527 aa)
FAM193AFamily with sequence similarity 193 member A. (1250 aa)
ST18ST18 C2H2C-type zinc finger transcription factor. (923 aa)
KIF4AKinesin family member 4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1236 aa)
DNM3Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (636 aa)
MYT1Myelin transcription factor 1. (1133 aa)
AP1S2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
FAM193BFamily with sequence similarity 193 member B. (820 aa)
DCTN4Dynactin subunit 4. (473 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (817 aa)
ARF1ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
MYT1LMyelin transcription factor 1 like. (1141 aa)
H0X251_OTOGACystatin domain-containing protein. (154 aa)
KIFAP3Kinesin associated protein 3. (773 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1218 aa)
LOC100954785Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
H0X155_OTOGAMHC_II_beta domain-containing protein. (89 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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