STRINGSTRING
CCNE2 CCNE2 H0Y2C4_OTOGA H0Y2C4_OTOGA LY6G5B LY6G5B RGS11 RGS11 SPHK1 SPHK1 GNG8 GNG8 GNG3 GNG3 GBA GBA GNA15 GNA15 H0XY69_OTOGA H0XY69_OTOGA H0XXA6_OTOGA H0XXA6_OTOGA H0XWL0_OTOGA H0XWL0_OTOGA H0XV70_OTOGA H0XV70_OTOGA TUBA4A TUBA4A GNB3 GNB3 FBXL3 FBXL3 HDAC3 HDAC3 LONP2 LONP2 GNB4 GNB4 XRN2 XRN2 FKBP9 FKBP9 AP3M2 AP3M2 STAT3 STAT3 PDC PDC WRAP53 WRAP53 FBXO4 FBXO4 ARFGEF2 ARFGEF2 CCT2 CCT2 H0WLB6_OTOGA H0WLB6_OTOGA CSNK2A2 CSNK2A2 PFDN1 PFDN1 TUBAL3 TUBAL3 GNG13 GNG13 CCT4 CCT4 GNG12 GNG12 GNG5 GNG5 CCT8 CCT8 NOP56 NOP56 GNB1 GNB1 GNGT1 GNGT1 GNG11 GNG11 TUBA8 TUBA8 CCNE1 CCNE1 H0WTR9_OTOGA H0WTR9_OTOGA ARFGEF1 ARFGEF1 KIFC3 KIFC3 GNG2 GNG2 PFDN2 PFDN2 DCAF7 DCAF7 FBXL5 FBXL5 TCP1 TCP1 GNG4 GNG4 USP11 USP11 H0WXG8_OTOGA H0WXG8_OTOGA GNB5 GNB5 CCT3 CCT3 CCT7 CCT7 GNA14 GNA14 GNAQ GNAQ TUBA1A TUBA1A PFDN5 PFDN5 GAPDHS GAPDHS FKBP10 FKBP10 SKIV2L SKIV2L LOC100959868 LOC100959868 FBXO6 FBXO6 FBXW2 FBXW2 CCT6B CCT6B RGS7 RGS7 LOC100954785 LOC100954785 CSNK2B CSNK2B RGS9 RGS9 FBXW7 FBXW7 PDCL PDCL FBXW9 FBXW9 FBXW5 FBXW5 TUBB1 TUBB1 RGS6 RGS6 ERMARD ERMARD KIF13A KIF13A GNB2 GNB2 GNA11 GNA11 PFDN4 PFDN4 VBP1 VBP1 AP3M1 AP3M1 TP53 TP53 H0XHF1_OTOGA H0XHF1_OTOGA FBXW4 FBXW4 H0XIR0_OTOGA H0XIR0_OTOGA CCT8L2 CCT8L2 H0XN74_OTOGA H0XN74_OTOGA TUBB6 TUBB6 GNG7 GNG7 LOC100958447 LOC100958447 H0XPI3_OTOGA H0XPI3_OTOGA H0XR11_OTOGA H0XR11_OTOGA H0XRG5_OTOGA H0XRG5_OTOGA ENSOGAP00000018960 ENSOGAP00000018960 H0XSA7_OTOGA H0XSA7_OTOGA CCT5 CCT5 H0XT67_OTOGA H0XT67_OTOGA PFDN6 PFDN6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCNE2Cyclin E2; Belongs to the cyclin family. (321 aa)
H0Y2C4_OTOGAT-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (375 aa)
LY6G5BLymphocyte antigen 6 family member G5B. (195 aa)
RGS11Regulator of G protein signaling 11. (466 aa)
SPHK1Sphingosine kinase 1. (384 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GBAGlucosylceramidase. (537 aa)
GNA15G protein subunit alpha 15. (374 aa)
H0XY69_OTOGAT-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (406 aa)
H0XXA6_OTOGAUncharacterized protein. (178 aa)
H0XWL0_OTOGAUncharacterized protein. (480 aa)
H0XV70_OTOGAT-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (415 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
GNB3G protein subunit beta 3. (340 aa)
FBXL3F-box and leucine rich repeat protein 3. (428 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (434 aa)
LONP2Lon protease homolog; Belongs to the peptidase S16 family. (818 aa)
GNB4G protein subunit beta 4. (341 aa)
XRN25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (951 aa)
FKBP9Peptidylprolyl isomerase. (574 aa)
AP3M2AP-3 complex subunit mu-2. (418 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
PDCPhosducin. (246 aa)
WRAP53WD repeat containing antisense to TP53. (540 aa)
FBXO4F-box protein 4. (387 aa)
ARFGEF2ADP ribosylation factor guanine nucleotide exchange factor 2. (1078 aa)
CCT2Chaperonin containing TCP1 subunit 2. (535 aa)
H0WLB6_OTOGAProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa)
PFDN1Uncharacterized protein. (122 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
GNG13G protein subunit gamma 13. (67 aa)
CCT4T-complex protein 1 subunit delta. (539 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CCT8Chaperonin containing TCP1 subunit 8. (547 aa)
NOP56NOP56 ribonucleoprotein. (581 aa)
GNB1G protein subunit beta 1. (340 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (410 aa)
H0WTR9_OTOGAUncharacterized protein. (129 aa)
ARFGEF1ADP ribosylation factor guanine nucleotide exchange factor 1. (1849 aa)
KIFC3Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (846 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
PFDN2Prefoldin subunit 2. (154 aa)
DCAF7DDB1 and CUL4 associated factor 7. (342 aa)
FBXL5F-box and leucine rich repeat protein 5. (668 aa)
TCP1T-complex 1. (556 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
USP11Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (915 aa)
H0WXG8_OTOGAUncharacterized protein. (490 aa)
GNB5G protein subunit beta 5. (397 aa)
CCT3T-complex protein 1 subunit gamma. (546 aa)
CCT7T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (542 aa)
GNA14G protein subunit alpha 14. (262 aa)
GNAQG protein subunit alpha q. (359 aa)
TUBA1ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
PFDN5Uncharacterized protein. (154 aa)
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase. (428 aa)
FKBP10Peptidylprolyl isomerase. (583 aa)
SKIV2LSki2 like RNA helicase. (1246 aa)
LOC100959868Uncharacterized protein. (255 aa)
FBXO6F-box protein 6. (284 aa)
FBXW2F-box and WD repeat domain containing 2. (460 aa)
CCT6BChaperonin containing TCP1 subunit 6B; Belongs to the TCP-1 chaperonin family. (536 aa)
RGS7Regulator of G protein signaling 7. (444 aa)
LOC100954785Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
RGS9Regulator of G protein signaling 9. (677 aa)
FBXW7F-box and WD repeat domain containing 7. (379 aa)
PDCLPhosducin like. (301 aa)
FBXW9F-box and WD repeat domain containing 9. (448 aa)
FBXW5F-box and WD repeat domain containing 5. (568 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (453 aa)
RGS6Regulator of G protein signaling 6. (437 aa)
ERMARDER membrane associated RNA degradation. (618 aa)
KIF13AKinesin family member 13A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1798 aa)
GNB2G protein subunit beta 2. (340 aa)
GNA11G protein subunit alpha 11. (359 aa)
PFDN4Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family. (134 aa)
VBP1Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (176 aa)
AP3M1AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family. (418 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
H0XHF1_OTOGATubulin_C domain-containing protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (305 aa)
FBXW4F-box and WD repeat domain containing 4. (411 aa)
H0XIR0_OTOGAUncharacterized protein. (154 aa)
CCT8L2Chaperonin containing TCP1 subunit 8 like 2. (527 aa)
H0XN74_OTOGATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC100958447Uncharacterized protein. (531 aa)
H0XPI3_OTOGAUncharacterized protein. (471 aa)
H0XR11_OTOGAUncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
H0XRG5_OTOGAUncharacterized protein. (64 aa)
ENSOGAP00000018960annotation not available (189 aa)
H0XSA7_OTOGAUncharacterized protein. (118 aa)
CCT5Chaperonin containing TCP1 subunit 5. (548 aa)
H0XT67_OTOGANop domain-containing protein. (445 aa)
PFDN6Uncharacterized protein. (129 aa)
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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